scholarly journals MONITORING OF NATURAL FOCAL INFECTIONS ON THE SOUTHERN EUROPEAN PART OF RUSSIA IN 2016

2018 ◽  
pp. 30-32 ◽  
Author(s):  
N.F. Vasilenko ◽  
O.V. Maletskaya ◽  
E.A. Manin ◽  
D.A. Prislegina ◽  
L.I. Shaposhnikova ◽  
...  
Keyword(s):  
Viral Encephalitis ◽  
Q Fever ◽  
Hemorrhagic Fever ◽  
European Part ◽  
West Nile Fever ◽  
Hemorrhagic Fever Virus ◽  
Granulocytic Anaplasmosis ◽  
European Part Of Russia ◽  
Federal Districts ◽  
Human Monocytic Ehrlichiosis

The results of epizootological monitoring of the Southern European part of Russia (Southern and North- Caucasian Federal Districts), which has been tested for 18 nosological forms of natural focal infections are presented. There have been tested the laboratory studies of 45 615 samples of field material, the markers of pathogens of 15 nosological forms are identified. The circulation of Crimean-Congo hemorrhagic fever virus is identified in 10 subjects, the pathogen of tularemia – in eight regions, Lyme borreliosis – in seven, Q fever – in six; pathogens of hemorrhagic fever with renal syndrome, West Nile fever, leptospirosis and human granulocytic anaplasmosis – in five subjects. The markers of pathogens of human monocytic ehrlichiosis and tick-borne viral encephalitis were detected in four subjects, pseudotuberculosis and intestinal yersiniosis – in three and Arboviruses (Sindbis, Inkoо, Tahyna) – in one region.

scholarly journals Epizootiological Monitoring of Natural Focal Infections in the South of the European Part of the Russian Federation in 2017

2019 ◽  
pp. 45-49
Author(s):  
N. F. Vasilenko ◽  
O. V. Maletskaya ◽  
D. A. Prislegina ◽  
E. A. Manin ◽  
O. V. Semenko ◽  
...  
Keyword(s):  
Russian Federation ◽  
Q Fever ◽  
Hemorrhagic Fever ◽  
European Part ◽  
The South ◽  
Hemorrhagic Fever Virus ◽  
Granulocytic Anaplasmosis ◽  
Control Research ◽  
The Russian Federation ◽  
Human Monocytic Ehrlichiosis

Objective– analysis of epizootiological manifestations of natural focal infections in the territory of the south of the European part of the Russian Federation in 2017.Materials and methods. Statistical documentation data from the Rospotrebnadzor Administrations, Centers of Hygiene and Epidemiology in the constituent entities of the Russian Federation, and Plague Control Research Institutes and Stations were used. The information was processed using Microsoft Excel 2010 software.Results and discussion. Epizootiological survey for 19 nosological forms of natural focal infections in the territory of the south of the European part of the Russian Federation was conducted. The total of 70155 samples of field material was tested; markers of 14 pathogens of natural focal infections were identified. The circulation of Crimean-Congo hemorrhagic fever virus was revealed in 11 constituent entities, tularemia and Lyme borreliosis pathogens – in 8 entities, West Nile virus – in 7. Markers of leptospirosis, Q fever, human granulocytic anaplasmosis and human monocytic ehrlichiosis pathogens were detected in 6 constituent entities, markers of the agent of hemorrhagic fever with renal syndrome – in 5 entities; markers of intestinal yersiniosis pathogen – in 3 constituent entities of the Russian Federation, pathogens of tick spotted fevers group, tick-borne viral encephalitis and pseudotuberculosis – in 2. The circulation of the virus Sindbis was identified in the Rostov Region. 

scholarly journals Genetic Monitoring of Crimean-Congo Hemorrhagic Fever Virus in the South of the European Part of Russia

2012 ◽  
pp. 80-85 ◽  
Author(s):  
A. S. Volynkina ◽  
A. N. Kulichenko
Keyword(s):  
Genetic Variants ◽  
Hemorrhagic Fever ◽  
Nucleotide Sequences ◽  
European Part ◽  
Clinical Samples ◽  
Virus Variant ◽  
Hemorrhagic Fever Virus ◽  
Cchf Virus ◽  
European Part Of Russia ◽  
First Time

Presented are the results of gene-typing of CCHF virus detected in clinical samples from CHF patients from the Stavropol, Rostov and Astrakhan Regions in 2011. For 28 samples determined are nucleotide sequences of the fragments 115–652 (S segment) and fragments 984–1469 (M segment). Philogenetic analysis of these nucleotide sequences demonstrated that typical strains circulated in 2011 in the regions under surveillance, importation of the new genetic variants of the virus did not take place. CCHF virus variant affiliated to the subgroup “Astrakhan-2” was detected in the clinical samples for the first time and characterized for its genome S- and M-segment fragments.

scholarly journals Results of Epizootiological Survey on Plague and Other Zoonotic Infections in the Northern Provinces of the Socialist Republic of Vietnam During Spring Months of 2019

2020 ◽  
pp. 133-138
Author(s):  
A. M. Porshakov ◽  
E. A. Chumachkova ◽  
Zh. A. Kas’yan ◽  
E. G. Oglodin ◽  
Luong Thi Mo ◽  
...  
Keyword(s):  
Small Mammals ◽  
Q Fever ◽  
West Nile Fever ◽  
Socialist Republic ◽  
Pathogenic Leptospira ◽  
Zoonotic Infections ◽  
Granulocytic Anaplasmosis ◽  
Tick Borne Encephalitis ◽  
Leptospira Spp ◽  
Human Monocytic Ehrlichiosis

Objective of the study is to detect circulation of plague agent and agents of other zoonotic infections (tularemia, pseudotuberculosis, leptospirosis, West Nile fever, Lassa fever, Dengue fever, Chikungunya fever, CrimeanCongo hemorrhagic fever, Q fever, Hantaviruses, tick-borne encephalitis, human monocytic ehrlichiosis, granulocytic anaplasmosis, and borreliosis) among small mammals and their ectoparasites in the territory of seven northern provinces of the Socialist Republic of Vietnam. Materials and methods. We have carried out epizootiological survey of seven northern provinces of the Socialist Republic of Vietnam (Dien Bien, Lai Chau, Lào Cai, Hà Giang, Lạng Sơn, Cao Bằng, and Quảng Ninh). Over the period of the study, 3400 trap/nights were accumulated, 179 specimens of small mammals caught, belonging to 10 species, 213 fleas of seven different species – collected, and 143 specimens of gamaside ticks falling under two species. The material gathered was investigated using enzyme immunoassay and polymerase chain reaction at the premises of mobile laboratory for monitoring and diagnostics. Results and discussion. Two-fold testing of 136 blood samples from small mammals revealed antibodies to F1 of Y. pestis in 14 (10.3 %) of them. Investigation of 158 samples of lung and kidney suspensions of small mammals showed that 22 (13.9 %) samples contained 16S rRNA of pathogenic leptospira, Leptospira spp. Analysis of 60 brain samples for the presence of Leptospira spp. revealed three (5.0 %) positive ones. 25 samples of gamaside ticks were tested for the presence of the DNA of Q fever, plague, tularemia and granulocytic anaplasmosis agents, and for the RNA of tick-borne encephalitis, human monocytic ehrlichiosis, and borreliosis agents. One sample (4 %) of gamaside ticks, Laelaps echidninus, contained RNA of Borrelia.

scholarly journals EPIZOOTOLOGIC MONITORING OF NATURAL-FOCAL INFECTIONS IN THE SOUTH OF RUSSIA IN 2015

2017 ◽  
pp. 29-35 ◽  
Author(s):  
N. F. Vasilenko ◽  
O. V. Maletskaya ◽  
E. A. Manin ◽  
D. A. Prislegina ◽  
V. M. Dubyansky ◽  
...  
Keyword(s):  
Viral Encephalitis ◽  
Viral Infections ◽  
Hemorrhagic Fever ◽  
The South ◽  
West Nile Fever ◽  
West Nile ◽  
Human Welfare ◽  
Natural Foci ◽  
Causative Agents ◽  
Federal Districts

Aim. Analyze epizootologic manifestations of natural-focal infections (NFI) in the south of Russia in 2015. Materials and methods. Reports provided by administrations of Federal Service of Surveillance for Protection of Consumers Rights and Human Welfare, Centers of Hygiene and Epidemiology, Research Institutes for Plague Control and Station for Plague Control were used. Data processing was carried out using Excel program. Results. A total of 37 738 samples of field material were studied, most of those - for tularemia (8268), Crimea hemorrhagic fever (6894) and West Nile fever (4875). Causative agents of 15 nosologic forms of NFI were detected during epizootologic examination of the territory of south of Russia, predominating amount of positive samples was obtained during study of material for tick-borne borreliosis (612), Crimea hemorrhagic fever (279) and tularemia (237). Conclusion. Analysis of epizootologic situation on natural-focal infections in the south of Russia gives evidence on the increase of activity of natural foci of bacterial (tularemia, tick-borne borreliosis), rickettsia (tick-borne spotted fevers) and viral infections (Crimea hemorrhagic fever, West Nile fever, tick-borne viral encephalitis), and thus problems of prophylaxis of natural-focal infectious diseases and constant monitoring of natural foci in subjects of Southern, North-Caucasian and Crimea federal districts are of particular importance.

scholarly journals Peculiarities of the Epidemic Situation on West Nile Fever in the Territory of the Russian Federation in 2018 and Forecast of its Development in 2019

2019 ◽  
pp. 17-25 ◽  
Author(s):  
I. O. Alekseychik ◽  
E. V. Putintseva ◽  
V. P. Smelyansky ◽  
N. V. Boroday ◽  
A. K. Alieva ◽  
...  
Keyword(s):  
Russian Federation ◽  
Incidence Rates ◽  
The European Union ◽  
West Nile Fever ◽  
West Nile ◽  
European Part Of Russia ◽  
Virus Genotypes ◽  
Federal Districts ◽  
The Usa ◽  
The Russian Federation

The epidemic rise in the incidence of West Nile fever (WNF) in the season of 2018 was observed in the countries of the European Union (EU) and bordering states and exceeded the values of all previously recorded epidemic rises of 2010–2012. An increase in the incidence rate was registered in the USA and Canada, however, it did not exceed the indicators of epidemic rises of 2007–2012. In the territory of the Russian Federation, the WNF epidemiological process became more intense mainly in the territory of the Southern and North Caucasian Federal Districts. In general, in Russia, the incidence rates were 2 times lower than the average annual rates, but significantly exceeded those of 2017. The epidemic process had a number of peculiarities in the seasonality, the structure of morbidity and the clinical manifestation of WNF. Genotyping of the isolated WNV RNA fragments from clinical and biological material showed that I, II and IV West Nile virus genotypes were circulating in the European part of Russia. Forecast of epidemic situation development in 2019 reveals further increase in the incidence and does not exclude the possibility of a significant localincrease of WNF incidence in certain regions of Russia. 

scholarly journals Detection of the RNA for new multicomponent virus in patients with Crimean-Congo hemorrhagic fever in southern Russia

2020 ◽  
Author(s):  
Vladimir Ternovoi ◽  
Anastasia Gladysheva ◽  
Alexandra Sementsova ◽  
Anna Zaykovskaya ◽  
Anna Volynkina ◽  
...  
Keyword(s):  
Phylogenetic Analyses ◽  
Hemorrhagic Fever ◽  
European Part ◽  
Viral Rna ◽  
Crimean Congo Hemorrhagic Fever ◽  
Viral Genomes ◽  
Cchf Virus ◽  
European Part Of Russia ◽  
Human Sera ◽  
Southern Russia

Background: Recently, a new multicomponent RNA-containing virus was described and called as Jingmen tick virus (JMTV) supposedly belonging to flaviviruses. A virus consists of four viral particles and JMTV was firstly isolated from ticks in China and South America. Aims: Detection viral RNA specific for JMTV complex, sequencing genome fragments and taxonomy identification novel virus from JMTV complex in patients with Crimean-Congo hemorrhagic fever (CCHF) from southern European part of Russia. Materials and methods: Panel of 20 randomly selected sera from patients with confirmed Crimean-Congo hemorrhagic fever was collected in 2016 and was used for detection JMTV and CCHF viral RNA by PCR with experimental primers. Subsequent sequencing of isolated fragments of viral genomes was used for identification JMTV and CCHF virus genetic materials and phylogenetic analyses. Results: The viral RNAs of the CCHF virus and JMTV were detected in blood of four patients. Sequencing of the isolated PCR fragment of S segment CCHF virus allowed identifying these RNA isolates as Europe 1 lineage, subgroups Va and Vb of the CCHF virus that is a typical for the southern European part of the Russia. The nucleotide sequences of segment 2 (GP glycoprotein) of the JMTV were also detected by RP PCR and sequencing in these human sera. The new JMTV isolates were clustered together by phylogenetic analysis. The level of nucleotide identity for newly discovered JMTV isolates was only about 81-82% with comparison to the previously described European variants (Kosovo) of the JMTV. Conclusions: The results suggest that viral genomic RNA for new multicomponent flavivirus named as Manych virus and related to the JMTV complex was discovered in sera of CCHF patients in Russia.

scholarly journals EPIDEMIOLOGIC SITUATION BY NATURAL-FOCI INFECTIONS IN THE CRIMEA FEDERAL DISTRICT IN 2014 - 2015

2016 ◽  
pp. 62-69
Author(s):  
A. Yu. Popova ◽  
A. N. Kulichenko ◽  
O. V. Maletskaya ◽  
N. F. Vasilenko ◽  
L. I. Shaposhnikova ◽  
...  
Keyword(s):  
Lyme Borreliosis ◽  
Q Fever ◽  
Spotted Fever ◽  
Hemorrhagic Fever ◽  
Federal District ◽  
West Nile Fever ◽  
Aim Analysis ◽  
The Crimea ◽  
Natural Foci ◽  
Causative Agents

Aim. Analysis of epidemic manifestations of natural-foci infections (NFI), clarification of spectrum of their causative agents, determination of epizootic activity of natural foci in the Crimea Federal District (KFD). Materials and methods. Epizootologic examination of 10 administrative districts of KDF was carried out. 291 pools (2705 specimens) of ixodes ticks and 283 samples of organs of small mammals were studied by PCR method for the presence of DNA/RNA of causative agents of a number of NFI. Results. Morbidity by NFI in KFD was registered by 6 nosologies: Lyme borreliosis, Marseilles fever, leptospirosis, tularemia, intestine yersiniosis and tick-borne viral encephalitis, wherein, transmissive infections made up 91.6%. Circulation of causative agents of Crimea hemorrhagic fever, Q fever, group of tick-borne spotted fever, Lyme borreliosis, human granulocytic anaplasmosis, human monocytic ehrlichiosis, hemorrhagic fever with renal syndrome, West Nile fever, tularemia and leptospirosis was established. Conclusion. Due to activity of natural foci of NFI further monitoring of epidemiologic and epizootologic manifestations of these infections in the Crimea, including using genetic methods of analysis, is necessary for ensuring sanitary-epidemiologic welfare of KFD population.

scholarly journals THEORETICAL ASPECTS OF CREATION OF SPECIFIC PREPARATIONS FOR ETIOTROPIC THERAPY AND PROPHYLAXIS OF WEST NILE FEVER AND CRIMEAN HAEMORRHAGIC FEVER

2016 ◽  
pp. 85-93
Author(s):  
V. I. Efremenko ◽  
A. A. Efremenko ◽  
D. V. Efremenko
Keyword(s):  
Theoretical Basis ◽  
Hemorrhagic Fever ◽  
Raw Material ◽  
West Nile Fever ◽  
West Nile ◽  
Healthy Donors ◽  
Central Regions ◽  
Natural Foci ◽  
Federal Districts ◽  
Regions Of Russia

Problematic issues on creation and practical introduction of specific immune biologic preparations for therapy and prophylaxis of natural-foci arbovirus infections - West Nile fever (WNF) and Crimean hemorrhagic fever (CHF), that are not available until now, are examined. Persistent natural foci of WNF and CHF with epidemic manifestations have formed in Southern and North Caucasian Federal Districts of Russia. Markers of Wfest Nile virus are being detected in central regions of Russia and Siberia, and the presence of fraction of population immune to this infection is also detected. Analysis of literature sources that has been carried out forms a theoretical basis for creation of novel specific preparations for etiotropic therapy and prophylaxis ofWNF and CHF. Use of blood from healthy donors with sufficiently high titers of class G immunoglobulins residing in certain subjects of Russian Federation in natural foci territories with the most intensive epidemic process is possible as raw material.

scholarly journals Arbovirus infections incidence in the south of the European part of the Russian Federation

2021 ◽  
Vol 98 (1) ◽  
pp. 84-90
Author(s):  
N. F. Vasilenko ◽  
D. A. Prislegina ◽  
O. V. Maletskaya ◽  
T. V. Taran ◽  
A. E. Platonov ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Russian Federation ◽  
Viral Encephalitis ◽  
Clinical Manifestations ◽  
European Part ◽  
Epidemiological Surveillance ◽  
The South ◽  
West Nile Fever ◽  
West Nile ◽  
The Russian Federation

Purpose: analysis of the arbovirus infections incidence in the south of the European part of the Russian Federation in 2015–2019.Materials and methods. Data from statistical documentation (epidemiological examination of the infectious disease cases, reports on the arbovirus infections incidence) reported by Departments of Rospotrebnadzor to Scientific and Methodological Center for monitoring pathogens of infectious and parasitic diseases of 1–3 risk groups for subjects of the North Caucasian and Southern Federal Districts were analyzed. The obtained data were processed using Microsoft Excel 2010 program.Results. In the south of the European part of the Russian Federation Crimean-Congo hemorrhagic fever (CCHF), West Nile fever (WNF), tick-borne viral encephalitis and dengue fever cases are registered annually.An expansion of the territory with registered epidemic manifestations of CCHF and WNF was noted, reflecting an increase in the area of circulation of their pathogens. An expansion of CCHF and WNF epidemic season with the involvement into the epidemic process of people from all age groups including young children was observed. Significant increase in number of imported cases of dengue fever was documented. Markers of tick-borne viral encephalitis, Batai, Inko, Sindbis, and Tyaginya fevers were detected in residents of a number of territories. A high levels of population humoral immunity to West Nile, Batai, Inko, Sindbis Tyaginya, Ukuniemi, Bhanja, Dkhori viruses were identified in the Astrakhan region.Conclusion. The data obtained indicate the need for epidemiological surveillance both for arbovirus infections with a pronounced epidemiological and clinical manifestations, and for infections, the proportion of which in the structure of infectious pathology in southern Russia has not been sufficiently studied, but carrying a potential risk of spreading.

scholarly journals Assessment of Epizootiological-Epidemiological Situation on Natural Focal Infections in Aleksandrovsk-Sakhalin Territory of the Sakhalin Region

2014 ◽  
pp. 11-15
Author(s):  
E. I. Andaev ◽  
M. V. Chesnokova ◽  
T. I. Borisova ◽  
E. A. Vershinin ◽  
S. A. Tatarnikov ◽  
...  
Keyword(s):  
Molecular Genetic ◽  
Genetic Material ◽  
West Nile Fever ◽  
Granulocytic Anaplasmosis ◽  
Current State ◽  
Tick Borne Encephalitis ◽  
Natural Foci ◽  
Tick Borne Encephalitis Virus ◽  
Human Monocytic Ehrlichiosis ◽  
Epidemiological Significance

Objective of the work was to carry out complex assessment of the current state of epizootic activity and epidemiological significance of the infectious disease natural foci in the Aleksandrovsk-Sakhalin territory of the Sakhalin Region. Trapped were 56 samples of small mammals in July, 2010; collected were 180 specimens of taiga tick imago, caught were 1000 specimens of mosquitoes. 223 samples of blood sera were taken from residents of the region. All the field data were tested to detect specific antibodies, antigens and genetic material of agents. Based on the results of epizootiological investigations, serological and molecular-genetic assays, demonstrated was the occurence of natural foci of leptospirosis, tularemia, tick-borne encephalitis, borreliosis, rickettsiosis, human granulocytic anaplasmosis, human monocytic ehrlichiosis, West Nile fever, Inco fever, Batai and Geto fevers, as well as HFRS with varying degree of activity manifestation in the territory of the region. Isolated was tick-borne encephalitis virus from mosquitoes.

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