scholarly journals UJI EFEK EKSTRAK DAUN LIDAH BUAYA (Aloe vera L.) TERHADAP PENYEMBUHAN LUKA INSISI KULIT KELINCI (Oryctolagus cuniculus)

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Christian A. Sewta ◽  
Christi Mambo ◽  
Jane Wuisan
Keyword(s):  
Wound Healing ◽  
Leaf Extract ◽  
Intestinal Tract ◽  
Aloe Vera ◽  
Rabbit Skin ◽  
Anti Oxidant ◽  
The Right ◽  
Tract Pain ◽  
Gastro Intestinal Tract ◽  
Anti Fungal

Abstract: Aloe vera has been used for thousands years to treat burns, hair loss, skin infections, sinus inflamation and gastro-intestinal tract pain. Previous researches showed that Aloe vera works effectively as anti-inflammatory, anti-pyretic, anti-fungal, anti-oxidant, anti-septic, anti-microbial, and anti-viral. This study aimed to evaluate the effect of aloe vera extract on wound healing in incised rabbit skin. This was an experimental study using 3 rabbits as test animals. The rabbits right and left backs were incised for 4 cm long and 2 mm deep. The wound on the right back was given aloe leaf extract , and the wound on the left back was not. The length of the wounds were measured everyday for 2 weeks. ResThe results showed that the wounds that were given aloe leaf extract dried and healed faster. Conclusion: Aloe vera extract accelerated wound healing in the incised rabbit skin.Keywords: aloe vera leaf extract, incision woundAbstrak: Lidah buaya digunakan sebagai bahan obat sejak beberapa ribu tahun yang lalu untuk mengobati luka bakar, rambut rontok, infeksi kulit, peradangan sinus, dan rasa nyeri pada saluran cerna. Beberapa peneliti terdahulu telah membuktikan bahwa Aloe vera berkhasiat sebagai antiinflamasi, antipiretik, antijamur, antioksidan, antiseptik, antimikroba, serta antivirus. Penelitian ini bertujuan untuk mengetahui efek pemberian ekstraksi lidah buaya terhadap penyembuhan luka insisi kulit kelinci. Penelitian ini mengunakan metode eksperimental, dengan menggunakan 3 ekor kelinci sebagai hewan uji. Punggung kanan dan kiri kelinci diinsisi sepanjang 4 cm dan kedalaman 2 mm. Luka pada punggung kanan diberi ekstrak daun lidah buaya sedangkan luka pada punggung kiri tidak diberi ekstrak daun lidah buaya. Pemberian ekstrak daun lidah buaya dan pengukuran panjang luka dilakukan setiap hari selama 2 minggu. Hasil penelitian memperlihatkan luka insisi kulit kelinci yang diberi ekstrak daun lidah buaya lebih cepat kering dan sembuh dibandingkan dengan luka insisi kulit kelinci yang tidak diberikan ekstrak daun lidah buaya. Simpulan: Pemberian ektrak daun lidah buaya memiliki efek untuk mempercepat penyembuhan luka insisi pada kulit kelinci.Kata kunci: ekstrak daun lidah buaya, luka insisi

scholarly journals Uji efektivitas ekstrak melati (Jasminum sambac) pada penyembuhan luka insisi kelinci (Oryctolagus cuniculus)

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Ni Luh G.L. Jayalandri ◽  
Edward Nangoy ◽  
Jimmy Posangi ◽  
Robert A. Bara
Keyword(s):  
Wound Healing ◽  
Oryctolagus Cuniculus ◽  
Leaf Extract ◽  
Antibacterial Effect ◽  
Chemical Substances ◽  
Incised Wound ◽  
Jasminum Sambac ◽  
The Right ◽  
Incision Wound ◽  
Sterile Gauze

Abstract: Flowers and leaves of jasmine (Jasminum sambac) have chemical substances that contain phytoconstituents such as alkaloids, glycosides, saponins, terpenoids and flavonoids. Flavonoid, an antioxidant, plays some importnat roles in wound healing due to their antibacterial effect. This study aimed to determine the effectiveness of jasmine leaf extract on incision wound healing in rabbits. This was an experimental study using three rabbits as test subjects. Wounds of 0.3 cm depth, 5 cm length, and 0.5 cm widened at both ends of the wound were made on the right and left sides of the back. Incised wound on the left side was treated with jasmine leaf extract ointment meanwhile the wound on the right side was untreated and was covered only with sterile gauze. Wounds were observed for two weeks to evaluate the changes of macroscopical length. The results showed that wounds treated with jasmine leaf extract ointment shrank and their edges united with the surrounding tissues faster than the untreated wounds. Conclusion: Jasmine leaf extract ointment accelerated incised wound healing in rabbits. Keywords : wound healing, incision wounds, jasmine leaves Abstrak: Bunga dan daun melati (Jasminum sambac) memiliki kandungan kimia yang berpotensi farmakologi seperti alkaloid, glycosid, saponin, terpenoid dan flavonoid. Flavonoid berpotensi sebagai antioksidan dan mempunyai kerja yang dibutuhkan dalam proses penyembuhan luka seperti antibakteri. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak daun melati pada penyembuhan luka insisi kelinci. Jenis penelitian ini eksperimental menggunakan tiga ekor kelinci sebagai hewan uji. Punggung kanan dan kiri kelinci diinsisi sedalam 0,3 cm dengan panjang 5 cm yang dilebarkan 0,5 cm pada kedua ujung sisi luka. Luka punggung kiri diberi salep ekstrak daun melati, luka punggung kanan tidak diberi perlakuan hanya ditutup kasa steril. Pengamatan selama dua minggu untuk melihat perubahan panjang luka secara makroskopik. Hasil penelitian mendapatkan bahwa luka yang diberi salep ekstrak daun melati lebih cepat mengecil serta memiliki permukaan luka yang rata dan menyatu dengan kulit sekitar dibandingkan luka yang tidak diberi salep ekstrak daun melati. Simpulan: Salep ekstrak daun melati memiliki efek untuk mempercepat penyembuhan luka insisi kelinci.Kata kunci: penyembuhan luka, luka insisi, daun melati

scholarly journals Various Phytochemicals Present in Maida Lakdi Litsea glutinosa (Lour) acts in the Management of Waja ul Mafasil (Arthritis) in a Clinical Trials

2021 ◽  
Vol 9 (11) ◽  
pp. 1-8
Author(s):  
Zaibunnisa Begum ◽  
Noor Banu Noorein ◽  
Shenaz Begum Modi
Keyword(s):  
Wound Healing ◽  
Clinical Trials ◽  
Joint Pain ◽  
Classical Text ◽  
Functional Activities ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Traditional Practitioners ◽  
Litsea Glutinosa ◽  
Anti Fungal

Litsea glutinosa (Lour) Maida Lakdi is an evergreen tree belonging to family Lauraceae it is a native to India.1,2,3 Ethinomedically the bark is used by the traditional practitioners as a demulcent, emollient and in the treatment of diarrhea and dysentery. According to ancient Unani classical text books by our ancient scholars which was used for mostly bony diseaseslike Fracture (kasar), Joint pain(Hudaar), gout(Naqras), sciatica(lrqun nasa), anti inflammatory(Muhalil e Auram), spacity of nerves(Tashannunj e Asab), nervine tonic(Muqavi e Asab)etc. and now a days further activities were found by various scientific studies paving a way for multi functional activities like Anti oxidant , analgesic anti inflammatory, anti pyretic, anti microbial, anti bacterial, anti fungal anti helminthic, wound healing, hepatoprotective, nephro protective, anti infertility,anti hyperglycemic and anti hyperlipidemic.

scholarly journals PENYEMBUHAN LUKA DECUBITUS PADA TIKUS PUTIH

2012 ◽  
Vol 1 (2) ◽  
Author(s):  
Moch. Agus Krisno Budiyanto
Keyword(s):  
Wound Healing ◽  
Leaf Extract ◽  
Chronic Wounds ◽  
Pressure Ulcers ◽  
Chronic Wound ◽  
Aloe Vera ◽  
Good Effect ◽  
White Rats ◽  
The Many ◽  
Community Pressure

Chronic wounds are still problem is one of the most frequent among the community. Pressure ulcers (decubitus) are examples of types of chronic wounds in which the maintenance costs of the injury fairly expensive. The use of plants is an appropriate alternative for the treatment of decubitus chronic wounds. One among the many plants that are known efficacious drugs for the health of Aloe vera. With the various components contained therein, aloe vera is known to affect the decubitus chronic wound healing. This study is purely experimental posttest-only design approach. The sample uses a white rats strain wistar female, weight 150-250 gr and 2,5 to 3 months of age. The variable is the concentration of the extract of Aloe vera and scores healing pressure ulcers (decubitus) degree II in white rats. The data obtained using observation, then analyzed with the assumption test (Lilliefors test and the Barlett test), one way Anova test and different test real distance of Duncan with significansy values of 0,05. The results indicate that there is the influence of various concentrations of leaf extract of Aloe vera to diameter decubitus chronic wound healing in rats and the concentration of leaf extract of Aloe vera 100% to give a good effect on the diameter of decubitus chronic wound healing on white rats (á 0.05).

scholarly journals An experimental study to test the haemostatic effect of Aloe vera

2019 ◽  
Vol 8 (4) ◽  
pp. 717
Author(s):  
Ramesh H. ◽  
Jyothi C. H.
Keyword(s):  
Wound Healing ◽  
Coming Out ◽  
Leaf Extract ◽  
Aloe Vera ◽  
Test Group ◽  
Water Bath ◽  
Control Group ◽  
Traditional System ◽  
Perennial Plant

Background: Blood clotting is a process which prevents blood loss during injuries. Blood clots even when it is coming out from the blood vessels. Aloe vera is a perennial plant found all over India. It is commonly used in traditional system of medicine for treatment of wound healing, mouth ulcers, constipation, skin wrinkles and diabetes mellitus It is also used as antioxidant and antimicrobial agent. As it is used in traditional system of medicine for wound healing, this study was under taken to test the possible haemostatic effect of aloe vera.Methods: 12 rats were divided into two groups (control and test) with 6 rats in each group. Determination of Bleeding Time (BT), rat tail was warmed for one minute in water at 40˚C and then dried. A small cut was made in the middle of the tail with a scalpel. In test group, a drop of aloe vera leaf extract was applied on the injured area immediately after making the cut in the middle of the tail, where as in the control group nothing was applied, and BT estimated. Determination of Clotting Time (CT), 12 test tubes were arranged in water bath at 37˚C. Control Group: 0.4 ml of blood was collected from each rat in the control group and added to 6 test tubes kept in the water bath. Test group: For the remaining 6 test tubes 0.1 ml of aloe vera leaf extract was added. 0.4 ml of blood collected from the test group was added to these test tubes. The CT was estimated for both control group and test group.Results: The results were statistically analyzed by using unpaired t-test. The reduction in BT and CT for test group was statistically highly significant (p<0.001) compared to control group.Conclusions: In this study aloe vera leaf extract significantly reduced both BT and CT in the test group.

scholarly journals Uji efek ekstrak daun dewa (Gyanurasegetum [Lour]. Merr) terhadap masa penyembuhan luka insisi kulit kelinci (Oryctolaguscuniculus)

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
. Aaron ◽  
Henoch Awaloei ◽  
Jane Wuisan
Keyword(s):  
Experimental Study ◽  
Wound Healing ◽  
Healing Process ◽  
Wound Healing Process ◽  
Rabbit Skin ◽  
The Public ◽  
Accelerate Wound Healing ◽  
Left And Right ◽  
The Right ◽  
Incision Wound

Abstract: Marsh fleabane (Gynurasegetum [Lour].Merr.) is one of the medicinal plants used by the public as an anti-septic to accelerate wound healing. The contents of Marsh fleabane that could accelerate wound healing are flavonoids, saponins, and atsiri oil. This study aimed to determine the effect of Marsh fleabane extract on wound healing incision of rabbit skin. This was an experimental study. This study was conducted in the Laboratory of Pharmacology and Therapeutics Faculty of Medicine, University of Sam Ratulangi. Samples were 3 rabbits. Incised wounds of 4 cm length and 2 mm depth were made on the rabbits’ left and right backs. The wounds on the left backs were given Marsh fleabane extract, meanwhile the wounds on the right backs were not treated. The results showed that the wound healing process of the incised wounds treated with Marsh fleabane extract was faster compared to the incised wounds without treatment. Conclusion: Marsh fleabane extract could accelerate the wound healing process of rabbit incised wound. Keywords: marsh fleabane, incision wound healing Abstrak: Daun dewa (Gyanurasegetum [Lour].Merr.) merupakan salah satu tanaman berkhasiat yang biasa digunakan oleh masyarakat sebagai obat anti septik dan mempercepat penyembuhan luka. Kandungan yang terkandung dalam daun dewa yang dipercaya dapat mempercepat penyembuhan luka yaitu flavonoid, saponin, dan minyak atsiri. Penelitian ini bertujuan untuk mengetahui uji efek ekstrak daun dewa terhadap penyembuhan luka insisi pada kulit kelinci. Metode penelitian yang digunakan ialah rancangan eksperimental. Penelitian ini dilaksanakan di Laboratorium Farmakologi dan Terapi Fakultas Kedokteran Universitas Sam Ratulangi. Sampel yang digunakan berjumlah 3 ekor kelinci yang masing-masing punggung kiri dan kanannya diberi luka insisi sepanjang 4 cm dan kedalaman 2 mm. Luka pada punggung sebelah kiri diberikan ekstrak daun dewa sedangkan luka pada punggung bagian kanan tidak diberikan ekstrak daun dewa. Hasil penelitian memperlihatkan bahwa masa penyembuhan luka insisi kulit kelinci yang diberikan ekstrak daun dewa lebih singkat dibandingkan dengan luka insisi kulit kelinci yang tidak diberikan ekstrak daun dewa. Simpulan: Ekstrak daun dewa berefek terhadap penyembuhan luka insisi kulit kelinci.Kata kunci: daun dewa, penyembuhan luka insisi

Aloe Vera – Nature’s Power

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Dr. Jyothsna Chowdary Kantam ◽  
Kavita Rai ◽  
Nandan N.
Keyword(s):  
Wound Healing ◽  
Dental Implants ◽  
Active Ingredient ◽  
Aloe Vera ◽  
Control Treatment ◽  
Oral Lesions ◽  
Mouth Rinse ◽  
Anti Oxidant ◽  
Plaque Control ◽  
Dental Applications

Aloe vera is a plant used in various fields like Homeopathy, Ayurveda, Allopathy, Siddha, Unani, cosmetology, dermatology and surprisingly even in dentistry. Aloe vera is richest source of health for humans with various benefits and properties like wound healing, anti-microbial, anti-inflammatory, immunomodulatory, anti-septic, anti-helmenthic and anti-oxidant. Aloe vera is used in dentistry as active ingredient in tooth pastes, tooth gels and mouth rinse for plaque control, treatment of various oral lesions, halitosis and gingivitis, as decontaminant in endodontics, in extraction sockets, dental implants and in denture care. This paper gives an overview of aloe vera plant, its ingredients, properties and various therapeutic and dental applications.

Short Report: The Moisture Balance with Aloe Vera Gel in Diabetic Wound Healing

2018 ◽  
Vol 1 (1) ◽  
pp. 21-23
Author(s):  
Fahrianto Selamet ◽  
Andi Mayasari Usman ◽  
Rian Adi Pamungkas
Keyword(s):  
Diabetes Mellitus ◽  
Wound Healing ◽  
Wound Care ◽  
Aloe Vera ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Short Report ◽  
Bacterial Reduction ◽  
Moisture Balance ◽  
Patients With Diabetes

Diabetic foot ulcer (DF) is a chronic complication of diabetes mellitus (DM), which impact on the morbidity, mortality and quality of patients’ lives.Of those patients with diabetes mellitus, approximately 15% to 25% developed to the foot ulcer. Beside has the infection and debridement of devitalized tissue downloading; the moisture imbalance becomes the factors of recalcitrant to healing. Moist wound healing is often contraindicated to the non-healable wounds. While wound care involves the debridement, bacterial reduction, and moisture balance in order to achieve the good granulation of the tissue development and adequate blood supply.

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