scholarly journals SEBARAN KEBIASAAN MEROKOK PADA PASIEN STROKE ISKEMIK YANG DI RAWAT INAP DI BAGIAN NEUROLOGI RSU PROF. DR. R. D. KANDOU MANADO

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Pricyllia Tumeleng ◽  
Theresia Runtuwene ◽  
Mieke Kembuan

Abstract: Stroke is the number one cause of disability and number two cause of death in the world. This disease has now become a serious health problem and is more common in developing countries. The increasing incidence of stroke is closely related to smoking as a lifestyle for most people. Smokers increase the risk of stroke by two to four times compared with those who did not smoke. This study aims to determine the distribution of the smoking habit frequency in ischemic stroke’s patients. This is a descriptive study. The population in this study are all ischemic stroke patients hospitalized in neurology department of Prof. Dr. R. D. Kandou hospital on November to December 2014 with a total sample of 42 patients with ischemic stroke. The results showed that most patients are male which there are 25 patients ( 59.5 % ), most of the patients are aged 46-55 years and 56-65 years were 13 patients ( 31 % ) , 57.1 % of patients as active smokers and 42.9 % are passive smokers, 83.4 % of patients with smoking duration >5 years, 70.8 % of patients smoked 11-20 cigarettes per day, 66.7 % of patients taking cigarettes filters, and 97.6 % had other risk factors other than smoking . Health workers are expected to provide counseling about the dangers of smoking, especially for those at risk of stroke.Keywords: ischemic stroke, smokingAbstrak: Penyakit stroke adalah penyebab cacat nomor satu dan penyebab kematian nomor dua didunia. Penyakit ini kini telah menjadi masalah kesehatan yang serius dan lebih sering terjadi di Negara-negara berkembang. Meningkatnya angka kejadian stroke berhubungan erat dengan merokok sebagai gaya hidup pada sebagian besar orang. Perokok meningkatkan resiko terjadinya stroke hingga dua sampai empat kali dibandingkan dengan mereka yang tidak merokok. Penelitian ini bertujuan untuk mengetahui distribusi frekuensi kebiasaan merokok pasien stroke iskemik. Penelitian ini bersifat deskriptif. Populasi dalam penelitian ini adalah seluruh pasien stroke iskemik yang di rawat inap di bagian neurologi RSU Prof. Dr. R. D. Kandou periode November sampai Desember 2014 dengan jumlah sampel sebanyak 42 pasien stroke iskemik. Hasil penelitian menunjukkan jenis kelamin yang terbanyak laki-laki yaitu sebanyak 25 pasien (59,5%), umur pasien sebagian besar 46-55 tahun dan 56-65 tahun sebanyak 13 pasien (31%), sebanyak 57,1% pasien sebagai perokok aktif dan 42,9% sebagai perokok pasif, 83,4% pasien dengan lama merokok >5 tahun, 70,8% pasien merokok sebanyak 11-20 batang perhari, 66,7% pasien mengkonsumsi rokok filter, dan 97,6% memiliki faktor risiko lain selain merokok. Tenaga kesehatan diharapkan dapat memberikan konseling tentang bahaya rokok terutama bagi mereka yang berisiko terkena serangan stroke.Kata kunci: stroke iskemik, merokok

2020 ◽  
Vol 25 (45) ◽  
pp. 4827-4834 ◽  
Author(s):  
Limin Zhang ◽  
Xingang Li ◽  
Dongzhi Wang ◽  
Hong Lv ◽  
Xuezhong Si ◽  
...  

Background: A considerable proportion of acute noncardiogenic ischemic stroke patients continue to experience recurrent ischemic events after standard therapy. Aim: We aimed to identify risk factors for recurrent ischemic event prediction at an early stage. Methods : 286 non-cardioembolic ischemic stroke patients with the onset of symptoms within 24 hours were enrolled. Vascular risk factors, routine laboratory data on admission, thromboelastography test seven days after clopidogrel therapy and any recurrent events within one year were assessed. Patients were divided into case group (patients with clinical adverse events, including ischemic stokes, transient ischemic attack, myocardial infarction and vascular related mortality) and control group (events-free patients). The risk of the recurrent ischemic events was determined by the receiver operating characteristic curve and multivariable logistic regression analysis. Results: Clinical adverse events were observed in 43 patients (case group). The mean levels of Mean Platelet Volume (MPV), Platelet/Lymphocyte Ratio (PLR), Lymphocyte Count (LY) and Fibrinogen (Fib) on admission were significantly higher in the case group as compared to the control group (P<0.001). Seven days after clopidogrel therapy, the ADP-induced platelet inhibition rate (ADP%) level was lower in the case group, while the Maximum Amplitude (MA) level was higher in the case group as compared to the control group (P<0.01). The Area Under the Curve (AUC) of receiver operating characteristic(ROC) curve of LY, PLR, , Fib, MA, ADP% and MPV were 0.602, 0.614, 0.629, 0.770, 0.800 and 0.808, respectively. The logistic regression analysis showed that MPV, ADP% and MA were indeed predictive factors. Conclusion: MPV, ADP% and MA were risk factors of recurrent ischemic events after acute noncardiogenic ischemic stroke. Urgent assessment and individual drug therapy should be offered to these patients as soon as possible.


2014 ◽  
Vol 42 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Heléne Starby ◽  
Hossein Delavaran ◽  
Gunnar Andsberg ◽  
Håkan Lövkvist ◽  
Bo Norrving ◽  
...  

2019 ◽  
Author(s):  
Nicolas Poupore ◽  
Dan Strat ◽  
Tristan Mackey ◽  
Ashley Snell ◽  
Thomas Nathaniel

Abstract Background Acute ischemic stroke attack with and without a recent TIA within or less than 24 hours may differ in clinical risk factors, and this may affect treatment outcomes following thrombolytic therapy. We examined whether the odds of exclusion or inclusion for thrombolytic therapy are greater in ischemic stroke with TIA less than 24 hours preceding ischemic stroke(TIA-24hr-ischemic stroke patients) as compared to those without recent TIA or non-TIA <24 hours.Methods A retrospective hospital-based analysis was conducted on 6,315 ischemic stroke patients, of whom 846 had proven brain diffusion-weighted magnetic resonance imaging (DW-MRI) of an antecedent TIA within 24 hours prior to ischemic stroke. The logistic regression model was developed to generate odds ratios (OR) to determine clinical factors that may increase the likelihood of exclusion or inclusion for thrombolytic therapy. The validity of the model was tested using a Hosmer-Lemeshow test, while the Receiver Operating Curve (ROC) was used to test the sensitivity of our model.Results In TIA-24hr-ischemic stroke population, patients with a history of alcohol abuse (OR = 5.525, 95% CI, 1.003-30.434, p = 0.05), migraine (OR=4.277, 95% CI, 1.095-16.703, p=0.037), and increasing NIHSS score (OR=1.156, 95% CI, 1.058-1.263, p = 0.001) were associated with the increasing odds of receiving rtPA, while older patients (OR = 0.965, 95% CI, 0.934‐0.997, P = 0.033) were associated with the increasing odds of not receiving rtPA.Conclusion In TIA-24hr-ischemic stroke patients, older patients with higher INR values are associated with increasing odds of exclusion from thrombolytic therapy. Our findings demonstrate clinical risks factors that can be targeted to improve the use and eligibility for rtPA in in TIA-24hr-ischemic stroke patients.


2018 ◽  
Vol 3 (2) ◽  
pp. 55
Author(s):  
Arif Iskandar ◽  
Suharyo Hadisaputro ◽  
Dwi Pudjonarko ◽  
Suhartono Suhartono ◽  
Dodik Tugasworo Pramukarso

Background: Ischemic stroke that occurs at the age of less than 45 years accounts for about 5 until 10 percent of the total stroke. This is influenced by changes in the life-style of modern society, such as changes in the pattern of food consumption, lazy to move, and smoking habits. This study aims to examine the effect of life-style on ischemic stroke at less than 45 years old people.Method: This study uses observational method with design of cases and controls. The samples are 86 observations consisting of 43 cases and 43 controls. Cases are patients with ischemic stroke less than 45 years of age and controls are non-stroke patients of neurology who are less than 45 years old.Results: The results show that the habit of consuming food containing high fat (p=0,032, OR=3,744, 95% CI=1,124-12,468) and smoking habit (p=0,019, OR=3.859, 95% CI=1,250-11,911) affect the occurrence of ischemic stroke at age less than 45 years. However, the habit of consuming red meat, consuming foods containing high salt, consuming drugs, and lack of physical activity do not affect the occurrence of ischemic stroke at age less than 45 years.Conclusion: The habits of consuming food containing high fat and smoking affect theoccurrence of ischemic stroke at age less than 45 years after hypertension, heart disease, and diabetes mellitus are controlled.


2020 ◽  
Vol 1 (2) ◽  
pp. 49
Author(s):  
Hijriyah Putri Tarmizi Hasibuan ◽  
Isra Thristy

Background: Stroke is the second largest cause of death in the world. Stroke is classified based on its etiology as ischemic stroke and hemorrhagic stroke. Most large-scale studies on the risk of total cholesterol and triglyceride levels in stroke are not distinguished between ischemic and hemorrhagic strokes. Purposes: The purpose of this study was to determine the comparison of triglyceride and total cholesterol levels in ischemic stroke patients with hemorrhagic stroke. Method: Descriptive analytic study using medical records of patients at Medan Haji General Hospital in 2018-2019. The number of ischemic stroke patients is 28 patients and hemorrhagic stroke 28 patients with a total sample of 56 patients. Results: In ischemic stroke patients, the average value of triglyceride levels was 144.75 mg/dL and the average value of total cholesterol was 250.93 mg/dL. In hemorrhagic stroke patients, the average value of triglyceride levels is 126.93 mg/dL and the average total cholesterol level is 174.25 mg/dL. Conclusion: From this study we found a significant difference in total cholesterol between ischemic and hemorrhagic strokes. No significant difference was found in triglycerides between ischemic and hemorrhagic strokes.


2019 ◽  
Author(s):  
Leah Wormack ◽  
Brice Blum ◽  
Benjamin Bailes ◽  
Thomas Nathaniel

Abstract Background. Specific clinical risk factors that may be associated with ambulatory outcome following thrombolysis therapy in ischemic stroke patients with pre-stroke depression is not fully understood. This was investigated. Methods. Multivariate analyses were performed to identify predictors of functional ambulatory outcomes. Patient demographics and clinical risk factors served as predictive variables, while improvement or no improvement in ambulatory outcome was considered as the primary outcome. Results. A total of 595 of these patients received rtPA of which 310 patients presented with pre-stroke depression, 217 had no improvement in functional outcome, while 93 patients presented with an improvement in functional outcome. Carotid artery stenosis (OR= 11.577, 95% CI, 1.281 – 104.636, P=0.029) and peripheral vascular disease (OR= 18.040, 95% CI, 2.956-110.086, P=0.002) were more likely to be associated with an improvement in ambulation. Antihypertensive medications (OR= 7.810, 95% CI, 1.401 –43.529, P=0.019),previous TIA (OR= 0.444, 95% CI, 0.517 –0.971, P=0.012), and congestive heart failure (OR= 0.217, 95% CI, 0.318 –0.402, P=0.030) were associated with a no improvement in ambulation. Conclusion. After adjustment for covariates, more clinical risk factors were associated with no improvement when compared with improvement in functional outcome following thrombolysis therapy in an acute ischemic stroke population with pre-stroke depression.


2016 ◽  
Vol 10 (2) ◽  
pp. 86-90 ◽  
Author(s):  
Cheung-Ter Ong ◽  
Sheng-Feng Sung ◽  
Yi-Sin Wong ◽  
Chi-Shun Wu ◽  
Yung-Chu Hsu ◽  
...  

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