scholarly journals Clinical Phenotypes Associated With Preterm Births at Jaramogi Oginga Odinga Teaching and Referral Hospital in Kisumu County, Kenya

2019 ◽  
Vol 3 (III) ◽  
pp. 175-186
Author(s):  
Edwin Omondi Juma ◽  
Margaret Keraka ◽  
Anthony Wanyoro

Preterm birth is a global health problem. It is the leading cause of child and neonatal mortality globally including Kenya. Preterm birth is the birth occurring before 37 completed weeks of gestation. In Kenya, preterm birth is the leading cause of neonatal mortality as it contributes to 35% of deaths among the neonates while Kisumu County is among the county’s leading with child under-five mortality rate at 133 deaths per 1000 live births. The main objective of this study was to identify the clinical phenotypes associated with preterm birth in JOOTRH in Kisumu County. It was a cross sectional study based on women who had a preterm birth alive or stillbirth at JOORTH in Kisumu County. Purposive sampling technique was used to select 178 respondents who met the inclusion criteria. Interviewer administered questionnaire was used to collect both qualitative and quantitative data. Data was analyzed by computer software SPSS version 23; descriptive statistics was used together with inferential statistics (Chi-square and Fisher’s Exact test) to help in the identification of the statistical significance of any association between the variables. A p value of < 0.05 was used. Bivariate analysis was utilized to measure the strength of associations. Data presented by use of frequency tables and narrative description. Ethical clearance was sought from Kenyatta University Ethics and Review Committee, permit sought from NACOSTI, consent and assent from the respondents. Results showed that maternal age (p=0.011) to be statistical significant with preterm births. Clinical phenotypes based on maternal, fetal and placental conditions; preeclampsia/eclampsia (p=0.016), extrauterine infections which includes malaria, UTI and HIV (p=0.030), severe maternal conditions that includes DM, anaemia, cardiac disease, hypertension prior to pregnancy and TB (p=0.001), multiple gestations (p=0.013), fetal anomaly (0.048), IUGR (p=0.049), antepartum stillbirth (p=0.046) and APH/early bleeding that include placenta previa and placenta abruption (p=0.025) were all significantly associated with preterm births. On bivariate analysis between clinical phenotypes and preterm births, all except multiple gestation (p=0.416) and APH (p=0.660) remained statistically significant. All clinical phenotypes (maternal, fetal and placental conditions) were significantly associated with preterm births. All clinical phenotypes except multiple gestations and APH/early bleeding remained statistically significant after bivariate analysis. The study recommends the use of Barro’s classifications system of clinical phenotypes to phenotype all preterm births in JOOTRH. Early identification of maternal, fetal and placental conditions identified in this study to be associated with preterm births by adopting Barros’ phenotyping of preterm births as a strategy to help prevent the occurrence of PTBs and eventually reduce neonatal deaths and under-five mortality.

2017 ◽  
Vol 5 (7) ◽  
pp. 1016-1020 ◽  
Author(s):  
Badriah Ali Alansi ◽  
Hytham Bahaeldin Mukhtar ◽  
Maher Ahmad Alazizi ◽  
Amjad Ahmad Zuiran ◽  
Areej Mohammed AL-Atawi ◽  
...  

AIM: To investigate risk factors for early preterm birth.METHODS AND MATERIAL: A retrospective comparative study was conducted at Tabuk, Kingdom of Saudi Arabia during the period from January to December 2010. Five hundred and ninety-five patient's files and delivery registry logbooks were reviewed, the following information was collected; demographic data, current and past obstetric histories. Then the early and late preterm births were compared for various risk factors. The Statistical Package for Social Sciences (SPSS version 22) was used. The Chi-square and t-test were used to test the statistical significance and a P-value<0.05 considered significant.RESULTS: Prevalence of early preterm birth was found to be 2.5% in our study group. Women at risk for early preterm birth were: primigravidas (33.7% vs. 26.2% for control), P-value 0.039, OR 1.429 and 95% CI 0.982 - 2.079); multiple gestations (87.7% vs. 95.1% for control, P-value 0.002, OR 0.368 and 95% CI 0.196 - 0.688); and patients with a prior history of placental abruption (3.7% vs. 1.0% for control, P-value 0.027, OR3.928 and 95% CI 1.1360 - 13.586).CONCLUSIONS: Current study indicated that early preterm births differed from preterm as a whole; primigravida, multiple gestations and a history of placental abruption are independent risk factors for them.


2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Eti Kurniawati

<p>Ascariasis incidence in children under five in the region work of Puskesmas Olak Kemang still a health problem that needs to be addressed, with a percentage of 51.0% is higher than in other wilayh. The disease is not lethal but can undermine the health of the human body so that the resulting decline in nutritional status, decreased intelligence and brain power or immune health in children.</p><p>               This research is a quantitative study using descriptive analytic method with cross sectional study design that aims to determine the relationship between the independent variables and the dependent variable. The population in this research that all children under five in the area of Puskesmas Olak Kemang, samples in this study were 75 children under five. Data were analyzed using analysis Univariate and Bivariate analysis with Chi-Square Test.</p><p>               The results showed that 78.0% of mothers of children under five who are not air personal hygiene, 60.4% of mothers of children under five unusual CTPS, 82.1% of respondents who did not state house meliliki latrine / WC. The results of the bivariate analysis showed that there was a significant relationship between personal hygiene (p-value = 0.000), customs CTPS (p-value = 0.001), latrine ownership (p-value = 0.000) with the incidence of intestinal worms in Puskesmas Olak Kemang Jambi.</p><p>               In connection with the results obtained, that the danger of de- worming is dependent on the cleanliness of his mother in serving as personal hygiene, CTPS and Owners toilets in every home. Thus the researchers suggested that the health center may be able to provide information to the public education about the dangers of de- worming to create a healthy society.</p><p> </p>Keyword                     :  Behavior, Children Events


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
H Cai ◽  
B W Mol ◽  
S Gordts ◽  
H Wang ◽  
J Shi

Abstract Study question If the elective single-blastocyst transfer (eSBT) strategy can be applied to women aged 36 or older. Summary answer In women ≥36 years old with at least two blastocysts, eSBT increased cumulative livebirth rate (LBR) while minimizing twins compared with double blastocyst transfer (DBT). What is known already: In young women with a good prognosis, eSBT policy is an accepted strategy to maintain LBR while decreasing multiple gestation. However, in many areas of the world DBT is still applied in older women. Study design, size, duration We performed a retrospective cohort study of 429 women aged ≥36 years or older who received IVF ovarian stimulation cycles between Jan 2015 and Oct 2018 and who had at least two blastocysts. Women were followed up until Oct 2020 for their fertility outcomes including cumulative live birth and multiple pregnancies. The study was performed at the Northwest Women and Children’s Hospital, Xi’an, China. Participants/materials, setting, methods Out of 429 women, 240 underwent a fresh cycle of eSBT and 189 DBT. The subsequent frozen-thawed embryo transfer cycles were a combination of single- and double- blastocyst transfers, more commonly the latter. Analysis was stratified for patients in age groups 36–37, 38–39 and ≥40 and quality of the blastocyst transferred, as graded by morphological examination. Outcomes were the LBR in the fresh cycle, cumulative LBR and multiple rate after fresh and frozen embryo transfers. Main results and the role of chance The cumulative LBR was 74.2% (178/240) for eSBT versus 63.0% (119/189) for DBT (OR = 1.69, 95%CI 1.12–2.56), irrespective of female age. The multiple rate was 9% (16/178) after eSBT versus 29.4% (35/119) after DBT (P- value &lt; .001). The total number of children born was 194 after eSBT versus 154 after DBT. Stratified by female age, the cumulative LBRs in women aged 36–37 (78.9 vs 70.5%), 38–39 (68.9 and 61.1%) and ≥ 40 years (59.3 and 47.5%), were higher after eSBT compared with DBT, however, the differences did not reach statistical significance in each subgroups. LBRs in the fresh cycles were comparable for patients with eSBT compared with DBT (52.1% vs. 52.4%, OR = 0.99, 95%CI 0.68–1.45). In women &lt; 40 years, DBT resulted in a small non-significant increase in LBR in the fresh transfer (63.2% vs. 61.2%, 95%CI=0.64–1.85, 36–37 years; 48.1% vs. 41.0%, 95%CI=0.64–2.80, 38–39 years) at the expense of a marked increase in twinning rate (0–5.4% vs. 31.7–34.6%). For women ≥40 years, no significant differences were observed in the LBR (37.0% vs 45%, 95%CI 0.47–4.07) or twinning rate (0 vs 7.7%) between eSBT and DBT group. The findings persisted with and without accounting for quality of the blastocyst transferred. Limitations, reasons for caution This study is limited by its observational character. Wider implications of the findings: In women ≥36 years with two blastocysts, eSBT should be the preferred treatment which maximizes the cumulative LBR for a decrease in the rate of multiple pregnancies. Trial registration number Not applicable


2019 ◽  
Vol 5 (2) ◽  
pp. 66-74
Author(s):  
Tutik Hidayati

The problem of malnutrition in children under five is still a major health problem in the world, including Indonesia. Indonesia is a developing country that still faces considerable problems of malnutrition. Nutritional problems nationally are under-five and under-nutrition children under five. Poor nutritional status is a condition of the body experiencing nutritional deficiencies or below standard. Based on the nutritional status monitoring (PSG) survey in Probolinggo District, there was an increase in cases of malnutrition, obtained in the prevalence of non-compliance with the weight per year in 2017 of 9.44%, an increase compared to 2016, namely 8.65% under-five children under five. Toddlers are considered the biggest nutritional risk because patterns of poor feeding have an impact on growth and development. This causes the toddler age group to increase the risk of morbidity and mortality. Based on a preliminary study in April 2018, data was obtained that Probolinggo was ranked second in the area of ​​malnutrition in East Java. In 2017 there are 130 toddlers who experience malnutrition in the Kalibuntu Coast of Probolinggo Regency. The cause of malnutrition is due to the pattern and intake of toddlers' food which contains less nutrition.The purpose of this study was to analyze the effect of nutritional support programs on feeding patterns and nutritional status of the Kalibuntu Coastal Children in Probolinggo Regency. This research is an experimental study, namely by measuring the increase / comparison of feeding patterns and nutritional status before and after the nutrition companion program. The population in this study were all toddlers with malnutrition in the Kalibuntu Coast of 130 people in Probolinggo Regency. Sampling uses Total Sampling. Samples are all mothers who have underweight and malnourished children under the age of 130 people in the Kalibuntu Coast of Probolinggo Regency. Data collection using observation sheets and interviews. Analysis of univariate data using frequency distribution, bivariate analysis using Wilcoxon match paired test and multivariate analysis using multiple linear regression then drawn conclusions. The results of the Wilcoxon match paired test between nutritional companions on feeding patterns obtained a p value of 0,000 <α 0,05, so ha was accepted so that there was an effect of nutritional companion on feeding patterns. The value of Exp (B) in the logistic regression analysis of eating parenting has a value of 85.008, which means that parenting has a chance of 85,008 times to change. While the nutritional status variable in multiple logistic regression has an Exp (B) value of 3.663, from these results it can be explained that nutritional status has an opportunity to increase 3.663 times.


2020 ◽  
Vol 11 (2) ◽  
pp. 59-70
Author(s):  
Ami Ami Oetamiati Wiharjo

Febrile convulsion (febris convulsion/stuip/step) i.e. seizures that arise at the time of fever not caused by processes in the head (brain : like meningitis or inflammation of the lining of the brain, ensifilitis or brain inflammation) but outside the head for example because of an infection in the respiratory tract, ear or infection in the digestive tract. Usually experienced by children aged 6 months to 5 years. In West Java Province in 2012 patients with febrile seizures in the Hospital amounted to 2,220 for ages 0-1 years, while there are 5,696 for ages 1-4 years. This study aims to determine the correlation between the level of knowledge of parents with first aid febrile seizures in children under five in the Aster room of Bogor Hospital in 2018. The type of research used is analitik korelatif with research design cross sectional. Sampling in this study with total sampling techniques a sample of this research is 35 respondents. Data collection was obtained through questionnaires in the form of closed questionnairestotaling 20 statements about first aid knowledge of febrile seizures and 14 questions about first aid febrile seizures. Analysis of the data used is univariat and bivariat (Chi-Square). Based on the knowledge of febrile seizures there were 21 (60.0%) respondents with good knowledge. Based on first aid febrile seizures in children under five there were 22 (62.9%) respondents with positive actions. Of the 35 respondents there were 18 (51.4%) respondents who had a good level of knowledge with positive first aid measures in febrile seizures. The results of bivariate analysis used an analysis test Chi-Square earned value p value 0,002≤0,05 (alpha), meaning Ha is accepted and H0 is rejected. Shows that is a correlation between the level of knowledge of parents and first aid in febrile seizures in children under five in the Aster of Bogor Hospital in 2018.


2021 ◽  
Vol 7 (2) ◽  
pp. 36-41
Author(s):  
Ikrama Hassan ◽  
◽  
Surajudeen Bello ◽  
Michael Anazodo ◽  
Abdulmumuni Ahmed Lawal ◽  
...  

Background: Preterm birth has been on the increase globally and accounting for morbidities and mortalities. Preterm delivery referred to the birth of a newborn prior to thirty seven completed gestational weeks. There is dearth of knowledge on the burden of preterm birth in this state. This study therefore determined the burden of preterm deliveries in Nasarawa State, evaluate the risk factors and identify the outcome of such deliveries. Methods: A descriptive cross-sectional study of all preterm delivered from the 1st of January 2014 to the 31st of December 2013 at the Dalhatu Araf Specialist Hospital (DASH) Lafia, General Hospital Akwanga and Medical Centre Mararaba Gurku in the Southern, Northern and Western senatorial zones of Nasarawa State respectively. Data was analyzed using SPSS version 20. Results: The mean age of mothers of preterm in this study is 26.5±5.7 years. More than three-quarter of preterm birth in Nasarawa State were at the DASH Lafia. The prevalence of preterm birth and admissions were 1.5% and 10.8% respectively. One in four of the preterm were either late preterm or extreme preterm. Singleton gestation accounted for 82.1% of the preterm births while 75.6% of such deliveries where through the vaginal mode of deliveries. Risk factors for preterm deliveries were multiple gestation, antepartum haemorrhage (placenta previa), premature rupture of membrane and previous preterm delivery. Deaths among the preterm was 11% in this study. Conclusion: The burden of preterm births in this study is comparable to other centre in same region. Half of the preterm were either late or extreme preterm. Risk factors for preterm deliveries were placenta previa, premature rupture of membrane, multiple gestation and previous preterm child birth. Death was recorded in one out of every nine preterm


2019 ◽  
Vol 8 (1) ◽  
pp. 42
Author(s):  
Elza Nur Fitriyah

Pneumonia is the leading cause of death among children under five years of age in the world. Based on Riskesdas 2007, in Indonesia the percentages of infants and children under five years who died due to pneumonia were 23.8 percent and 15.5 percent respectively. Using a non-reactive unobstructive method, this study aimed at analyzing the relationship between nutrition and the immunization status and the incidence of pneumonia among children under two years old. This study employed secondary data of Laporan Bulanan Kesehatan Ibu dan Anak dan Laporan Gizi (monthly reports of maternal care, child wellbeings, and nutritions) at Bulak Banteng primary health center in the year of 2015. The sample in this study was 604 children under two years selected using a simple random sampling method. The data was obtained by collecting data of children under two years and the incidence of pneumonia among children under two years at Bulak Banteng health center in 2015. Using a bivariate analysis, it showed that there was relationship between variables of age, sex, immunization, and nutritional status, and the incidence of pneumonia. The p value and OR variables used respectively are 0.00 OR 3.6; 0.00 OR 1.6; 0.00 OR 3.2 and 0.00 OR 16.6. The conclusion of this study is that there was a significant relationship between the variables of age, sex, immunization, and nutritional status and the incidence of pneumonia among children under two years. The advice to primary health centers is to give PMT (additional nutritious food) to children under two years without good nutritional statuses and to monitor the health status of patients who have pneumonia with home visits to avoid recurrence.


2021 ◽  
Vol 33 (1) ◽  
pp. 102-114
Author(s):  
S.N. Esomonu ◽  
E.N. Ossai ◽  
A.T. Onajole

Background: Malaria is a life-threatening parasitic disease caused by the plasmodium parasite and women and under-five children are more prone to its adverse consequences. The use of insecticide-treated nets (ITNs) is recommended to reduce malaria burden in endemic communities. The study aimed to determine knowledge of malaria and utilization of insecticide-treated nets (ITNs) amongst mothers of under-five children in rural communities of Nigeria’s Federal Capital Territory, and the predictors.Methods: A community-based cross-sectional design was used. Multi-stage sampling method was used to select 160 mothers of under-five children in two rural communities. A structured questionnaire was used for data collection. Data analysis was done using SPSS statistical software version 22.0 and level of statistical significance was determined by a p value of < 0.05.Results: Mean age of respondents was 29.0±5.4 years, and majority 144 (90%) of the women were married. Lower proportion of respondents had good knowledge of malaria 33 (20.6%). Ninety-four (58.8%) of respondents owned ITNs, but less than half 45 (47.9%) utilized the nets. Predictors of good knowledge of malaria were having attained tertiary education [Adjusted Odds Ratio (AOR); 2.7, 95% Confidence Interval (CI):1.1–8.1], p=0.042, and being self-employed, (AOR; 3.4, 95% CI: 1.1-13.1), p=0.043). Predictor of utilization of ITNs was being aged 30 years and above (AOR; 2.5, 95% CI: 1.1-6.1, p=0.031).Conclusion: Lower proportions of respondents had good knowledge of malaria and utilization of ITNs. Health education of mothers on malaria and benefits of ITNs use should be intensified in the study area.


Author(s):  
Shahnawaz Hasnain Warsi ◽  
Kripa Nath Mishra

Background: Monochorionic twins showed increased incidence of discordant growth as compared to dichorionic twins. Studies have reported fivefold mortality of twins in comparison with singleton pregnancy. In this a prospective study is done to assess the perinatal, neonatal mortality and morbidity in multiple gestations. Zygosity determines the degree of risk of chromosomal abnormalities in each fetus of a multiple gestation. The risk for aneuploidy in each fetus of an MZ pregnancy is the same as a singleton pregnancy, and except for rare cases of genetic discordancy, both fetuses are affected. In a DZ pregnancy, each twin has an independent risk for aneuploidy, and therefore has twice the risk of having a chromosomal abnormality compared with a singleton. Material and methods: This prospective observational study was conducted in the Department of Paediatrics Darbhanga Medical College and Hospital, Darbhanga Bihar India. The time period of the study from May 2019 to feb 2020. The total number of multiple gestation 160 include in this study. Results: Total 160 twins were studied, out of which preterm deliveries constituted 80.6% of all deliveries. Most of the mothers were between 24 to 30 year age group 70(43.8 %) followed by 18 to 24 year 55 (34.4 %) and most of them were primi 97(60.6%) and followed by gravid 2 was 54 (33.8%). Out of 160 patients 29 patient s was family history of twining in 18.1% of the study group. Assisted reproductive techniques such as clomiphene cirate,IUI and IVF  were used by 19.4% of couples. Dichorinic diamniotic twins accounted for 84.4% and Dichorinic triamniotic 2.4 %  of the  total  multiple deliveries. Normal Vaginal delivery was done for 65.6% of twins and LSCS for 34.4%. Conclusion: Most common type of delivery was vaginal delivery (65.6%) followed by LSCS (34.4%).Out of the variables studied, significant influence on neonatal mortality was seen only with discordant twins


Author(s):  
Sugiarto Sugiarto ◽  
Subakir Pitriyani ◽  
Pitriyani Pitriyani

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p align="center"><strong><em>Abstract</em></strong></p><p><em>Problems with diarrhea are still a relatively large problem. In 2017 the number of diarrhea among toddlers in Indonesia was 40.07% and there were 21 times diarrhea outbreaks in 12 provinces, 17 districts / cities. Jambi Province in 2017 the prevalence of diarrhea in infants is 43.79%. In the city of Jambi the prevalence of diarrhea in children under five was 6.5%. This study aims to look at the risk factors for diarrhea in infants. This research is a quantitative research with case control research design. Case samples were 30 people and control samples were 60 people, the comparison of the number of cases and controls was 1: 2, then the number of samples in the study were 90 toddlers. Data collection was done by filling out questionnaires with univariate and bivariate analysis using the chi square test. The analysis showed that there was a relationship between hand washing with soap and running water (p - value = 0.013 &amp; OR = 3,824), exclusive breastfeeding (p - value = 0,000 &amp; OR = 5,902), nutritional status (p - value = 0,001 &amp; OR = 6,625), Latrine Quality (p - value = 0.001 &amp; OR = 5,035) and source of clean water (p - value = 0,009 &amp; OR = 4,333) on the incidence of diarrhea in children under five. Variables that are at risk for the incidence of diarrhea in infants are hand washing with soap and running water, exclusive breastfeeding, nutritional status, latrine quality and clean water sources</em><em></em></p><p><strong><em>Keywords:</em></strong><em> <strong>risk factor</strong></em><strong><em>s; </em></strong><strong><em>diarrhea</em></strong><strong><em>; Children</em></strong><strong></strong></p></td></tr></tbody></table></div>


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