scholarly journals PENGARUH PENERAPAN MODIFIKASI PERILAKU SEHAT TERHADAP FAKTOR RESIKO DM TIPE II

2016 ◽  
Vol 2 (1) ◽  
pp. 86
Author(s):  
Ernawaty Siagian
Keyword(s):  
Blood Glucose ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Fasting Blood Glucose ◽  
Healthy Diet ◽  
Control Group ◽  
Significant Difference ◽  
Diet And Exercise ◽  
Experimental Group

ABSTRAK Pendahuluan: Banyak penelitian mengindikasikan pengaruh modifikasi perilaku sehat terhadap faktor resiko DM tipe II. Tujuan: penelitian ini bertujuan untuk menguji pengaruh paket modifikasi perilaku sehat terhadap terhadap faktor resiko DM tipe II pada orang dewasa terlepas dari jenis kelamin (laki-laki dan perempuan sebagai subyek), usia 40-65 tahun dan bertempat tnggal di Bandar lampung. Metode: penelitian ini menggunakan desain penelitian quasi eksperimental yang menggunakan pre dan post test dengan 30 orang dewasa. 15 orang untuk control group dan 15 orang dewasa untuk eksperimen group. Penelitian ini  dibatasi hanya 10 (sepuluh) hari untuk menentukan pengaruh penerapan modifikasi perilaku sehat terhadap faktor resiko DM tipe II dengan tindak lanjut pemeriksaan gula darah puasa dan total kolesterol. Hasil: Eksperimen group dan control group menunjukkan tingkat gula darah puasa yang tinggi sebelum 10 (sepuluh) hari intervensi diet diabetic dan olah raga. Kedua group eksperimen dan kontrol group menunjukkan tingkat yang tinggi dari total kolesterol  sebelum intervensi 10 (sepuluh) hari diet diabetic dan olah raga. Adanya perbedaan yang signifikan dalam  gula darah puasa dan tingkat total kolesterol pada subyek sebelum dan sesudah pelaksanaan diet diabetic dan olah raga antara eksperimen group dimana terdapat penurunan yang nyata. Terdapat penurunan yang signifikan dalam gula darah puasa dan tingkat total kolesterol dari subyek di eksperimen group setelah pelaksanaan diet diabetic dan olah raga. Namun control group menunjukkan tidak ada perubahan sama sekali setelah 10 (sepuluh) hari dibandingkan dengan  eksperimen group. Usia sebagai variabel intervening menunjukkan tidak ada perbedaan yang signifikan dalam  gula darah puasa pada subyek. Pada tingkat total kolesterol untuk  nilai pre test dan post test control group adalah sebanding, sedangkan untuk eksperimen group menunjukkan  dengan bertambahnya usia subyek, tingkat total kolesterol mereka menurun. Jenis kelamin tidak menunjukkan perbedaan perbedaan yang signifikan dalam gula darah puasa pada subyek dan tingkat total kolesterol. Diskusi: ada penurunan nyata yang signifikan dalam gula darah puasa dan  total kolesterol pada subyek setelah  pelaksanaan 10 (sepuluh) hari diet diabetic dan olah raga diantara eksperimen group, sementara tidak ada perubahan sama sekali untuk control group. Usia dan jenis kelamin tidak membuat perbedaan yang signifikan dalam  gula darah puasa mereka, tetapi total kolesterol mereka menurun dengan meningkatnya usia mereka. ABSTRACT Introduction: Enough studies indicate the affect of healthy life behaviors on type 2 diabetes mellitus risk factors. Objective: the primary aim of the study is to determine the effect of health related behavior modification package on type 2 diabetes mellitus risk factors of at-risk adults irrespective of gender (men and women subjects) ages 40-65 years old residing in Bandar Lampung, Indonesian. Method: this study uses a quasi experimental research design that uses pre and post test with 15 adults for control group and 15 adults for experimental group. It is only limited to determine the effect of (10) ten day health related behavior modification package consisting of  healthy diet, and exercise with follow-up fasting blood glucose, and total cholesterol. The experimental and control group have shown a high level of fasting blood glucose level before the 10 (ten) days intervention of healthy diet and exercise. Result: both experimental and control group have shown a borderline high level of total cholesterol before the 10 (ten) day intervention of healthy diet and exercise. However, the control group has shown no changes at all after 10 (ten) days compared to the experimental group which is labeled as normal. There is a significant difference in the fasting blood glucose and total cholesterol level of the subjects before and after the implementation of healthy diet and exercise among the experimental group in which a decrease is markedly noted. Discussion: there is a significant decrease in the fasting blood glucose and total cholesterol level of the subjects in the experimental group after the implementation of healthy diet and exercise. Age as an intervening variable shows no significant difference in the subjects’ fasting blood glucose level. However, in the subjects’ total cholesterol level, for control group it is comparable whereas for experimental group it shows that as the age of the subject increases, their total cholesterol level decreases. Gender shows no significant difference in the subjects’ fasting blood glucose and total cholesterol level. It is concluded that there is a markedly significant decrease in the fasting blood glucose and total cholesterol level of the subjects after the 10 (ten) days implementation of healthy diet and exercise, among the experimental group, while no change at all for the control group. The subject’ age and gender makes no significant difference in their fasting blood glucose level but their total cholesterol decreases as their age increases.

scholarly journals Prevention of Increasing Total Cholesterol Level Using Cowpea Yoghurt

2020 ◽  
Vol 3 (1) ◽  
pp. 38
Author(s):  
Maulana Rahmat Hidayatullah
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Lipoprotein Metabolism ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
Metabolism Disorder ◽  
Significant Difference ◽  
Coa Reductase

Atherosclerosis is lipoprotein metabolism disorder which is marked by an increase of total cholesterol level in blood serum. Cowpea contains a lot of isoflavones that can inhibit the activity of the enzyme HMG-CoA reductase in the cholesterologenesis process. The aim of this study is to find out cowpea yogurt which can prevent the increasing total cholesterol level. This study used an experimental study with a post-test only control group design in 30 male rats. It was divided into 5 groups: Results showed that the total cholesterol level among the fifth group was a significant difference (Kruskal-Wallis, p = 0,000). The conclusion of this study is cowpea yogurt can prevent the increasing total cholesterol levels of Wistar rats induced by a high-fat diet.

Role of Nutrition Counseling and Lifestyle Modification in Managing Prediabetes

2021 ◽  
pp. 037957212110254
Author(s):  
Harleen Kaur ◽  
Neerja Singla ◽  
Rohini Jain
Keyword(s):  
Hemoglobin A1c ◽  
Lifestyle Modification ◽  
Fasting Blood Glucose ◽  
Nutrition Intervention ◽  
Control Group ◽  
Population Prevalence ◽  
Significant Difference ◽  
And Control ◽  
Experimental Group

Objective: India is the second country after China having the highest population prevalence of diabetes. Several research studies investigating diabetes have been done, but not much work has been done on prediabetes. The purpose of this study was to investigate the effect of nutrition and lifestyle modification on prediabetic females. Methods: A total of 120 prediabetic females from Ludhiana city were divided into 2 matched groups: control group (n = 60) and experimental group (n = 60). Impact of nutrition intervention for dietary and lifestyle modification (for 3 months) was assessed on the anthropometric, dietary, biochemical parameters, and diabetes risk score of the experimental group and control group (no intervention). Results: All the selected 120 subjects completed the study (experimental group = 60; control group = 60). There was significant difference in the changes between the 2 groups throughout the study. The fasting blood glucose and glycated hemoglobin A1c levels of the experimental group subjects reduced significantly ( P ≤ .01). However, no change was observed among the control group subjects. The lipid profile of the experimental group showed a significant improvement ( P ≤ .01). Conclusion: Nutrition counselling of the prediabetics regarding dietary and lifestyle modification is recommended so as to improve their metabolic control, thus preventing them from being diabetics.

scholarly journals The effect of oat bran consumption on gestational diabetes: a randomized controlled clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zahra Barati ◽  
Mina Iravani ◽  
Majid Karandish ◽  
Mohammad Hosein Haghighizadeh ◽  
Sara Masihi
Keyword(s):  
Clinical Trial ◽  
Blood Glucose ◽  
Gestational Diabetes ◽  
Fasting Blood Glucose ◽  
Intervention Group ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Standard Diet ◽  
Oat Bran ◽  
Significant Difference

Abstract Background Gestational diabetes is the most common medical complication in pregnancy, and it has many side effects for the mother and the fetus. The aim of this study was to evaluate the effect of oat bran consumption on gestational diabetes. Methods This study is a randomized clinical trial that was performed on 112 women with gestational diabetes treated with diet. Participants were randomly divided into two groups of 56. Participants in both groups were given a diet for gestational diabetes. In addition to the diet, the intervention group received 30 g of oat bran daily for 4 weeks at lunch and dinner. Tests of fasting blood glucose and two-hour postprandial (2hpp) glucose were taken from both groups: before the intervention, and 2 and 4 weeks after the start of the intervention. Data analysis was performed using SPSS statistical software (version 22) using independent t-test, as well as Chi-square and Mann-Whitney tests. P values less than 0.05 were considered statistically significant. Results There was no statistically significant difference between the two groups in terms of mean blood glucose before the intervention, while 2 and 4 weeks after the intervention, mean fasting blood glucose and two-hour postprandial (2hpp) glucose decreased significantly in the intervention group compared with the control group (P < 0.001). Conclusion Based on the results of this study, the addition of oat bran to the standard diet for pregnant women with gestational diabetes reduced fasting blood glucose and two-hour postprandial (2hpp) glucose. More detailed studies with higher sample sizes are recommended to prove the effectiveness of this valuable dietary supplement. Trial registration IRCT registration number:IRCT20191220045828N1. Registration date: 2020-04-18. Registered while recruiting.

scholarly journals UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL BUAH CABAI MERAH ( Capsicum annuum L. ) TERHADAP MENCIT PUTIH JANTAN

2019 ◽  
Vol 9 (1) ◽  
pp. 86 ◽  
Author(s):  
Zulkarni Zulkarni
Keyword(s):  
Blood Glucose ◽  
Capsicum Annuum ◽  
Fasting Blood Glucose ◽  
Ethanol Extract ◽  
Negative Control ◽  
Control Group ◽  
Glucose Levels ◽  
Capsicum Annuum L ◽  
Blood Glucose Levels ◽  
Significant Difference

This Research was conducted to determine the effect of ethanol extract from red chilli (Capsicum annuum L)in lowering blood glucose levels of hyperglycemic male white mices. This study used 30 malewhitemices and divided into 6 groups: negative control group, the positive control group, the treatmentgroup withdosage of 200 mg / kgweight, 400 mg / kgwieght, 600 mg / kg weight and a comparison group with glibenclamide with dosage of 5 mg / kgweightadministered orally for 21 days. The level of fasting blood glucose was checked 6 days after dexamethasone induced, and after the ethanol extract of red chilies on day 7th, 14th, and 21st. The data was analyzed statistically with one –way and two-way Anova by usingSPSS16 program and proceed with the test Duncan to look the significant difference between treatments. The results showed that the ethanol extract from red chilies with a dosage of 200mg / kgweight, 400mg / kgweight, 600 mg / kgweight showed the effect in lowering blood sugar levels in male white mices hyperglycemia significantly (p <0.05). The duration ethanol extract of red chili affected blood glucose levels. The most effective duration in lowering blood glucose levels is the administration of a preparation within 21 days.

scholarly journals Preliminary Results on the Effectiveness of a Nutrition Intervention in Lowering Diabetes Risk in Prediabetic People Living with HIV (PLWH) in MASH Cohort (OR36-06-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Alicia Sneij Perez ◽  
Adriana Campa ◽  
Leslie Seminario ◽  
Sabrina Martinez ◽  
Fatma Huffman ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Intervention Group ◽  
Nutrition Intervention ◽  
Control Group ◽  
Reactive Protein ◽  
Research Initiative ◽  
Significant Difference ◽  
Hs Crp

Abstract Objectives The objective of this study is to assess the effectiveness of a 6-month nutrition intervention to improve glycemic parameters and inflammation in prediabetic PLWH on stable ART with undetectable HIV viral load. Methods A 6-month randomized, controlled nutrition intervention was conducted in prediabetic PLWH. The study participants for the intervention were recruited from the Miami Adult Studies for HIV (MASH) cohort at the FIU-Borinquen Research Clinic. Upon their consent, the participants were randomized into the intervention group or the control group. Participants randomized in the intervention group met once a month for approximately 1 hour where they received medical nutrition therapy, nutrition counseling and nutrition education; participants randomized into the control group received educational material at baseline. Blood was drawn at baseline and at 6-month to measure fasting blood glucose (FBG) and high sensitivity C-reactive protein (hs-CRP). Results A total of 38 participants were recruited and randomized into either the intervention group (n = 20) or the control group (n = 18). We found that the FBG for the 6-month follow-up for the intervention group was significantly lower than the baseline FBG values of the same study group (paired t-test; P = 0.031). No significant difference was found in the control group between the baseline and 6-month fasting blood glucose values (P = 0.068). Moreover, no significant difference was found in pre/post C-reactive protein (CRP) levels in the intervention or control group (paired t-test; P = 0.404 and P = 0.117 respectively). There was a significant difference in CRP levels at baseline (P = 0.028) between the study groups but no difference at the 6-month follow up (Mann Whitney U test: P = 0.430). Conclusions The results from this intervention support the notion that a nutrition intervention is effective in prediabetic PLWH to lower diabetes risk by significantly lowering fasting blood glucose and may be implemented into larger scale interventions; however, no significant changes was seen in hs-CRP values between the 2 groups. Funding Sources National Institute of General Medical Sciences (NIGMS): Research Initiative for Scientific Enhancement (RISE), Biomedical Research Initiative (BRI) Grant, National Institute on Drug Abuse 5U01DA040381-03 and FIU-Dissertation Funding.

scholarly journals Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus)

2014 ◽  
Vol 3 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Indrawati Wurdianing ◽  
SA Nugraheni ◽  
Zen Rahfiludin
Keyword(s):  
Treatment Group ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Ldl Cholesterol ◽  
Total Cholesterol Level ◽  
Wilcoxon Test ◽  
Control Group ◽  
Annona Muricata ◽  
The Mean

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.

scholarly journals Profile of Blood Glucose and Insulin after Vitamin C and Vitamin E Supplementation on Active Teenagers

2018 ◽  
Vol 7 (4.26) ◽  
pp. 136
Author(s):  
Irfiansyah Irwadi ◽  
Hayuris Kinandita ◽  
Jamaluddin Mahmud ◽  
Lilik Herawati
Keyword(s):  
Blood Glucose ◽  
Vitamin E ◽  
Vitamin C ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Combination Group ◽  
Control Group ◽  
High Dose ◽  
Moderate Dose ◽  
Significant Difference

Aim: Antioxidants, such as vitamin C and vitamin E, is widely used as supplements. The aim of this study is to analyze the profile of blood glucose, serum insulin, and  HOMA in active teenagers after vitamin C and vitamin E supplementation.Methods: Subjects (14-16 y.o) consisted of 12 boys and 5 girls, divided into 3 groups: control (4 boys, 2 girls), ‘moderate dose’ of vitamin C and vitamin E combination group (5 boys, 1 girls), and ‘high dose’ of vitamin C and vitamin E combination group (3 boys, 2 girls). The treatment was given for 5 days. Vitamin C and vitamin E for ‘moderate dose’ was 500mg;  200IU, and for ‘high dose’ was 1000mg; 400IU. Fasting Blood Glucose (FGB) and 1 hour BG (1hr_BG), fasting serum insulin (FSI) and 1 hour SI (1hr_SI) was collected after treatment. We also calculated the HOMA-IR and HOMA-β.Result: There was no significant difference on FBG, 1hr_BG, FSI, 1hr_SI, HOMA-IR, and HOMA-β (p≥ 0.05). However, mean FBG and 1hr_BG tended to be higher on the treatment groups. The control group had the lowest HOMA-IR and the highest HOMA-β.Conclusions: We suggest that the supplementation of vitamin C and vitamin E in active teenagers is not essential on glucose homeostasis.  

Effect of feeding synbiotic products on the serum cholesterol, HDL cholesterol and non- HDL cholesterol level of albino rats

2018 ◽  
Author(s):  
Rakesh Kumar ◽  
Binita Rani ◽  
Sonia Kumari ◽  
A K Jha
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol ◽  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
Blood Cholesterol ◽  
Control Group ◽  
Albino Rats ◽  
Therapeutic Benefits ◽  
Effect Of Feeding

Considering the excellent bio-therapeutic benefits of Lactobacillus and Bifidobacterium, this study exploited the probiotic characteristics of Lactobacillus acidophilus-015, Lactobacillus casei-297 and Bifidobacterium bifidum-229 strains with natural prebiotic substances viz. banana powder, malto-dextrin and honey to produce synbiotic food formulations and to study the effect of feeding their on the cholesterol level (mg/dl) of albino rats. On the basis of the preliminary investigation, synbiotic products with 2% banana powder, with 2% malto-dextrin, with 3% honey and synbiotic product with 2% each of, banana powder and malto-dextrin and 1% of honey were selected for the investigation of the total cholesterol, HDL-cholesterol and non-HDL cholesterol. The products showed a significant decrease in total cholesterol level, however the control group receiving the cholesterol rich laboratory diet showed a significant increase (P LESS THEN 0.01) in the total cholesterol after 45 days of feeding. There was 25.81 to 45.05% reduction of serum cholesterol was observed in case of feeding synbiotic formulations. Increase in the HDL-cholesterol and decrease in the non-HDL cholesterol were also significant. Therefore, synbiotic formulation with all these three natural prebiotic have enhanced ability to decreased down the blood cholesterol level.

scholarly journals Red dragon fruit (Hylocereus spp.) peel marmalade effectively improve blood glucose and lipid profile of hypercholesterolemic wistar rats

2020 ◽  
Vol 9 (1) ◽  
pp. 61-67
Author(s):  
Natalia Desy Putriningtyas ◽  
Intan Permatasari ◽  
Dita Oktaviani ◽  
Anastasia Servia Raha ◽  
Siti Wahyuningsih
Keyword(s):  
Blood Glucose ◽  
Functional Food ◽  
Wistar Rats ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Fruit Peel ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Dragon Fruit ◽  
Significant Difference

Background: Polyphenols, antioxidants, dietary fiber, and vitamin contained in the red dragon fruit peel. Red dragon fruit peel can be processed into marmalade. Red dragon fruit peel marmalade has the potential to be a functional food. Functional food is food that has a physiological function based on scientific studies.Objectives: The objective of this study is to analyze the effect of red dragon fruit peel marmalade on fasting blood glucose levels, HDL, LDL, and triglycerides levels of hypercholesterolemic Wistar rats.Methods: This study used a pre-&post-test control group design. Hypercholesterolemic male Wistar rats were randomly assigned into five groups. Hypercholesterolemia was induced by 1% cholesterol powder and 0.5% cholic acid for two weeks. All groups received standard chow. Samples were grouped into five groups: K-; K+; K1 (0.94 g/kg b.wt/day); K2 (1.41 g/kg b.wt/day); K3 (1.88 g/kg b.wt/day). The intervention was carried out for 28 days. GDP level was measured using the GOD-PAP. HDL, LDL, and triglyceride were analyzed with spectrophotometry. GDP, HDL, LDL, and triglyceride levels were measured twice before fasting. A paired t-test and one-way ANOVA were used to analyze the data.Results: The result showed that K-; K1; K2; K3 had a significant difference between groups before and after the intervention (p<0.05). Red dragon fruit peel Marmalade was able to reduce the levels of GDP, LDL, triglycerides, and increase HDL (p <0.05).Conclusion: Red dragon fruit peel marmalade reduced fasting blood glucose levels, LDL, triglyceride levels, and increased HDL levels of hypercholesterolemic Wistar rats.

scholarly journals Promoting non-communicable disease risks in rural area: a Community and Family Health Care - inter professional education (CFHC-IPE) activity

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Dea Aryas Nugrahani ◽  
Diannisa Ikarumi Enisar Sangun ◽  
Khansa Anindya ◽  
Niken Kuntolowati
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Health Status ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Professional Education ◽  
Total Cholesterol Level ◽  
Family Health ◽  
Health Examination ◽  
Random Blood Glucose

Health is an aspect that could be viewed from various age groups and factors. Risk factors found during Community and Family Health Care-Inter Professional Education visits in Pondok 2, Widodomartani, Ngemplak are the habits of people who still lacking in controlling excessive consumption of sugar, salt, and oily foods. These may lead to  many problems such as hypertension, diabetes mellitus and hypercholesterolemia. Based on the problem, our group held the community service activities focusing on health screening, particularly on the measurement of blood pressure, random blood glucose, and total cholesterol level.  This activity aims  to screen the community health condition and to raise health awareness and understanding. Therefore, people may start to take action improving their lifestyle in order to maintain their long term health status. This research is a retrospective study using secondary data obtained from health examination records at the time of community service. The health check-up was conducted on May 4, 2019. We utilize mannual mercury sphygmomanometer for blood pressure measurement and automatic skin prick test device for random blood glucose and total cholesterol level. During the health examination, we also counsel the subjects about healthy lifestyle. Sixteen people from the targeted community attended the activity. Half of the people had normal blood pressure;  1 person pre-hypertension; 4 persons stage I hypertension, and 3 persons stage II hypertension.  For random blood glucose measurement, only 1 resulted in high random blood glucose whilst others were within normal limit.  Total cholesterol level was examined to 9 people with history of hypercholesterolemia with the following results; 2 people had high level, 2 people had borderline-high level ,and the rest had normal level. Most of the people within the community had good health status. This kind of activity can be routinely conducted not only to screen community health status but also to promote health awareness.

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