scholarly journals RELATIONSHIP BETWEEN SERUM LEVEL OF IONIZED CALCIUM, MAGNESIUM, PHOSPHATE, VITAMIN D AND PARATHYROID HORMONE WITH STAGES OF CKD.

2020 ◽  
Vol 14 (1) ◽  
pp. 49-54
Author(s):  
A Mohammed ◽  
HM Suleiman ◽  
R Yusuf ◽  
IS Aliyu ◽  
A Ibrahim ◽  
...  
2018 ◽  
Vol 37 (5) ◽  
pp. 825-834
Author(s):  
Chang Kyun Choi ◽  
Sun-Seog Kweon ◽  
Young-Hoon Lee ◽  
Hae-Sung Nam ◽  
Kyeong-Soo Park ◽  
...  

Author(s):  
Atul K. Sharma ◽  
Sina Gallo ◽  
Catherine A. Vanstone ◽  
Sherry Agellon ◽  
Mary L’Abbé ◽  
...  

AbstractIonized calcium (iCa) is believed to be the principle determinant of parathyroid hormone concentration (PTH). However, previous studies contained few infants.This ancillary study from our vitamin DNo significant correlations were observed between iCa and PTH at individual visits (p>0.2). After accounting for repeated measures, PTH decreased with increasing iCa (slope –5.25; 95% confidence intervals (CI) –8.78 to –1.73), decreased with increasing 25(OH)D (slope –0.006; 95% CI –0.009 to –0.002, and increased with later visits (6–12 months, p<0.001),We observed a weak negative relationship between iCa and PTH and an increase with age consistent with physiologic maturation.


1993 ◽  
Vol 234 (2) ◽  
pp. 195-200 ◽  
Author(s):  
M. RUDNICKI ◽  
J. THODE ◽  
T. JØRGENSEN ◽  
B. L. HEITMANN ◽  
O. H. SØRENSEN

Author(s):  
D. M. Kvitka ◽  
V. O. Palamarchuk ◽  
S. V. Zemskov ◽  
V. A. Smoliar

Background. The postoperative hypoparathyroidism remains a specific complication in the thyroid surgery. The incidence of iatrogenic hypoparathyroidism ranges from 3.0 % to 31.5 %. The decrease in the level of parathyroid hormone leads to the launch of a cascade of the electrolyte changes. The standard methods for controlling and correcting hypoparathyroidism do not guarantee the prevention of hypocalcemiacases. The role of calcium and magnesium in the conduction of the nerve impulses along muscle fibers is well known. The study of the role of magnesium will enable further correction of the manifestations of postoperative hypoparathyroidism.Aim — to study a relationship between postoperative hypoparathyroidism, changes in calcium-magnesium metabolism and their clinical manifestations; to analyze the effects of hypomagnesemia on the clinical manifestations of hypocalcemia; to study the possibility of correcting calcium-magnesium metabolism in the postoperative period.Materials and methods. The study involved 145 patients operated for the thyroid diseases. The patients were divided into two groups. The main group (n = 73) included the patients who took magnesium medications in the preoperative period for 10—14 days at a dose of 1500—2000 mg/day. In the observation group (n = 72), the patients did not take the magnesium medications. Parameters of the parathyroid hormone, ionized calcium, and magnesium were measured in all patients in the preoperative period and on the first day of the postoperative period. The parathyroid hormones’levels on the first day of postoperative period were ranged into the “ranges”: 1) parathyroid hormone — ≤ 1 pg/ml, 2) parathyroid hormone — 1—5 pg/ml, 3) parathyroid hormone — 5—10 pg/ml, 4) parathyroid hormone — > 10 pg/ml. The clinical manifestations of hypoparathyroidism were assessed on a scale: not pronounced, poorly pronounced, pronounced, sharply pronounced.Results. The correlations were found between the levels of the postoperative magnesium, ionized calcium and parathyroid hormone. In the main group, the number of the pronounced and sharply pronounced manifestations of hypocalcemia was observed in the parathyroid hormone range — ≤ 1 pg/ml. In the observation group, the largest number of the prono­unced and sharply pronounced clinical manifestations was recorded in the parathyroid hormone range — ≤ 1 pg/ml, parathyroid hormone — 1—5 pg/ml. In the main group, in comparison with the observation group, the total number of the clinical manifestations of hypocalcemia was lower.Conclusions. There were revealed the positive cor­rela­tions in the changes in the levels of the parathyroid hormone, ionized calcium and magnesium. It has been proven that uncorrected hypomagnesemia in the early postoperative period can be a predictor of the clinical manifestations of hypoparathyroidism. The correction of the serum magnesium levels in most patients reduces the clinical manifestations of hypocalcemia.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1407-1407
Author(s):  
H. Jamilian

IntroductionVitamin D deficiency has been associated with an increased risk of depression and schizophrenia in some studies. However, a few epidemiological studies do not show consistent results.ObjectivesComparing serum level of Vitamin D, parathyroid hormone, Calcium, and phosphorus in schizophrenic and depressed patients with healthy subjects in Iranian people.MethodsIn a cross-sectional study, 100 patients with schizophrenia and 100 major depressed ones in Arak-Iran from October 2009 to April 2010, and also 100 healthy subjects were enrolled. After informed consent, serum levels of Vitamin D, Calcium, Phosphorus, and parathyroid hormone were assessed by using routine laboratory methods.Data was analyzed by using SPSS V17, one-way ANOVA, the post-hoc test of Tukey and also in general linear models.ResultsThe three groups were different in Vitamin D (PValue < 0.001). Post-hoc analysis of Tukey showed that Vitamin D level of healthy participants was significantly higher than depressed patients (PValue < 0.001) and schizophrenics (PValue = 0.001) while there was no significant difference between Vitamin D levels in depressed and schizophrenic patients (PValue = 0.563). Serum levels of Ca, P and PTH were the same in three groups.ConclusionsOur findings suggest that Vitamin D affects the brain independent of hormonal pathways which regulate serum level of calcium. Lack of difference between the serum levels of Vitamin D in schizophrenia and depression suggests that the independent effect of Vitamin D in the brain is a general effect and is not specific for a region or pathway in the brain.


2014 ◽  
Vol 34 (2) ◽  
pp. 166-167
Author(s):  
Gurmeet Singh ◽  
Karuna Thapar ◽  
Preeti Malhotra

Pseudohypoparathyroidism is a genetic disorder that is similar to hypoparathyroidism, but which results from the body’s lack of response to parathyroid hormone rather than its decreased production. Serum level of immunoreactive Parathormone are elevated instead. We report a four month old infant in status epilepticus associated with hypocalcemia, hyperphosphatemia and raised parathyroid hormone level. Hypocalcemia was resistant to calcium therapy initially but responded to vitamin D analogue therapy leading to diagnosis of Pseudohypoparathyroidism. DOI: http://dx.doi.org/10.3126/jnps.v34i2.10602 J Nepal Paediatr Soc 2014;34(2):166-167 


2018 ◽  
Vol 47 (2) ◽  
pp. 765-771 ◽  
Author(s):  
Canser Yilmaz Demir ◽  
Muhammet Eren Ersoz

Objective To assess vitamin D, parathyroid hormone, calcitonin, calcium, phosphorus and magnesium levels in patients with versus without temporomandibular disorders (TMDs). Methods This prospective observational study included patients with TMDs and age-matched healthy controls. TMDs were diagnosed via physical and radiologic examination, and serum levels of 25 (OH) vitamin D, parathyroid hormone, calcitonin, calcium, magnesium, and phosphorus were determined. The impact of age, sex and seasonal variations in serum 25 (OH) vitamin D levels was controlled by the inclusion of age, sex and date-matched control patients. Results The study included 100 patients, comprising 50 patients with TMDs and 50 control patients. No statistically significant between-group differences were found regarding age or sex. No statistically significant between-group differences were found in terms of serum 25 (OH) vitamin D, calcitonin, calcium, magnesium or phosphorus levels. Parathyroid hormone levels were statistically significantly higher in patients with TMDs versus healthy control patients. Conclusion In patients with temporomandibular disorders, increased parathyroid hormone levels in response to vitamin D deficiency was significantly more prominent. These data suggest that, in patients with temporomandibular disorders, vitamin D deficiency should be assessed and corrected.


Author(s):  
Mahnoosh Fatemi ◽  
Maryam Allahdadian ◽  
Mehrnoosh Bahadorani

Background: Premenstrual syndrome (PMS) is a common problem among women and is identified by reversal emotional, psychological, and physical signs during the luteal phase. These signs, however, lower down in the follicular phase. The cause of PMS isn’t very well-known up to now control group and many researchers have suggested that mineral compounds and vitamins can inhibit these symptoms. Objective: The objective of this study is to compare the serum level of some trace elements and vitamin D between normal controls and patients with PMS. Materials and Methods: 300 female students (19–21 yr old) from Falavarjan County were randomly selected and asked to complete a standard questionnaire on PMS during three menstruation cycles. The students were divided into two groups: healthy persons (control) and PMS persons, and PMS was determined on the basis of the answers to the questionnaire. Thereafter, the serum concentrations of zinc, iron, calcium, magnesium, potassium, sodium, and Vitamin D3 were measured and compared between the two groups. Results: Our results showed that the PMS prevalence was about 41.5%. The level of vitamin D decreased in both the control and PMS groups, with a significantly lower range of vitamin D (p 0.05) in the PMS group. Other factors had no significant change between the two groups. Conclusion: Vitamin D deficiency was probably one of the most important causes of unpleasant symptoms of PMS between these students. Key words: Premenstrual syndrome, Trace elements, Vitamin D.


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