scholarly journals A CROSS SECTIONAL DESCRIPTIVE STUDY OF OCD IN CHILDREN AND ADOLESCENTS

2020 ◽  
pp. 1-4
Author(s):  
Chhitij Srivastava ◽  
Abhishek Pratap Singh ◽  
Zeeshan Anwar ◽  
Santosh Kumar Kesharwani
Keyword(s):  
Children And Adolescents ◽  
Rating Scale ◽  
Demographic Data ◽  
Positive Family History ◽  
Clinical Information ◽  
Obsessive Compulsive ◽  
Degree Relative ◽  
Cross Sectional ◽  
Multicentric Study ◽  
Children’S Depression

This study was a part of a bigger multicentric study to examine the socio-demographic and clinical characteristics of children and adolescents (age ≤18 years) with OCD. Our sample comprised 30 subjects with OCD. Socio-demographic data was collected on a proforma specifically designed for this study. Clinical information was obtained on Structured clinical interview for Diagnostic and Statistical Manual, 5th edition Research Version (SCID), Children’s Yale Brown Obsessive Compulsive Scale (CYBOCS), the Children’s Depression Rating Scale–Revised (CDRS) and the Family Interview for Genetic Studies (FIGS). In our sample 70% of participants were male and 67.7% had onset of symptoms before 14 years of age. Most common obsessions in our participants were of doubts about contamination and magical thinking/superstitious while the most common compulsions were those involving checking, washing and rituals involving other persons. Comorbid psychiatric disorders were seen in 63.3% patients with most common being depression, Obsessive Compulsive Related Disorders (OCRDs), intermittent explosive disorder and anxiety disorder. The associated OCD symptoms on CYBOCS including lack of insight, avoidance and indecisiveness were on a spectrum. 46.6% had positive family history of OCD in first degree relative.

Safety, Tolerability, and Efficacy of Desvenlafaxine in Children and Adolescents with Major Depressive Disorder: Results from Two Open-Label Extension Trials

CNS Spectrums ◽  
2018 ◽  
Vol 24 (5) ◽  
pp. 496-506 ◽  
Author(s):  
Sarah Atkinson ◽  
Louise Thurman ◽  
Sara Ramaker ◽  
Gina Buckley ◽  
Sarah Ruta Jones ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Children And Adolescents ◽  
Rating Scale ◽  
Transition Period ◽  
Extension Study ◽  
Open Label ◽  
Major Depressive ◽  
Children’S Depression ◽  
Flexible Dose

ObjectiveTwo similarly designed extension studies evaluated the long-term safety and tolerability of desvenlafaxine for the treatment of children and adolescents with major depressive disorder (MDD). Efficacy was evaluated as a secondary objective.MethodsBoth 6-month, open-label, flexible-dose extension studies enrolled children and adolescents who had completed one of two double-blind, placebo-controlled, lead-in studies. One lead-in study included a 1-week transition period prior to the extension study. Patients received 26-week treatment with flexible-dose desvenlafaxine (20–50 mg/d). Safety assessments included comprehensive psychiatric evaluations, vital sign assessments, laboratory evaluations, 12-lead electrocardiogram, physical examination with Tanner assessment, and Columbia-Suicide Severity Rating Scale. Adverse events (AEs) were collected throughout the studies. Efficacy was assessed using the Children’s Depression Rating Scale–Revised (CDRS-R).ResultsA total of 552 patients enrolled (completion rates: 66.4 and 69.1%). AEs were reported by 79.4 and 79.1% of patients in the two studies; 8.9 and 5.2% discontinued due to AEs. Treatment-emergent suicidal ideation or behavior was reported for 16.6 and 14.1% of patients in the two studies. Mean (SD) CDRS-R total score decreased from 33.83 (11.93) and 30.92 (10.20) at the extension study baseline to 24.31 (7.48) and 24.92 (8.45), respectively, at week 26.ConclusionDesvenlafaxine 20 to 50 mg/d was generally safe and well tolerated with no new safety signals identified in children and adolescents with MDD who received up to 6 months of treatment in these studies. Patients maintained the reduction in severity of depressive symptoms observed in all treatment groups at the end of the lead-in study.

scholarly journals Factors associated with reporting of abuse against children and adolescents by nurses within Primary Health Care

2014 ◽  
Vol 22 (6) ◽  
pp. 1048-1055 ◽  
Author(s):  
Ana Carine Arruda Rolim ◽  
Gracyelle Alves Remigio Moreira ◽  
Sarah Maria Mendes Gondim ◽  
Soraya da Silva Paz ◽  
Luiza Jane Eyre de Souza Vieira
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Children And Adolescents ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Graduate Studies ◽  
Cross Sectional ◽  
Topic Identification ◽  
Factors Associated ◽  
Primary Health

OBJECTIVE: to analyze the factors associated with the underreporting on the part of nurses within Primary Health Care of abuse against children and adolescents.METHOD: cross-sectional study with 616 nurses. A questionnaire addressed socio-demographic data, profession, instrumentation and knowledge on the topic, identification and reporting of abuse cases. Bivariate and multivariate logistic regression was used.RESULTS: female nurses, aged between 21 and 32 years old, not married, with five or more years since graduation, with graduate studies, and working for five or more years in PHC predominated. The final regression model showed that factors such as working for five or more years, having a reporting form within the PHC unit, and believing that reporting within Primary Health Care is an advantage, facilitate reporting.CONCLUSION: the study's results may, in addition to sensitizing nurses, support management professionals in establishing strategies intended to produce compliance with reporting as a legal device that ensures the rights of children and adolescents.

Citalopram in Children and Adolescents with Depression or Anxiety

2002 ◽  
Vol 36 (11) ◽  
pp. 1692-1697 ◽  
Author(s):  
Jennifer L Baumgartner ◽  
Graham J Emslie ◽  
M Lynn Crismon
Keyword(s):  
Anxiety Disorder ◽  
Adverse Effects ◽  
Children And Adolescents ◽  
Emotional Disorders ◽  
Rating Scale ◽  
Depressive Symptomatology ◽  
Care Center ◽  
Tertiary Care ◽  
Secondary Outcome ◽  
Children’S Depression

OBJECTIVE: To investigate the efficacy and tolerability of citalopram in children and adolescents. METHOD: Retrospective chart review of 17 outpatients treated with citalopram at a tertiary care center. Subjects were diagnosed with a depressive or anxiety disorder with or without comorbidities and may have received concurrent medications. The primary outcome measure was the Clinical Global Impression Improvement Scale (CGI-I). Secondary outcome measures were the Children's Depression Rating Scale—Revised (CDRS-R), Inventory of Depressive Symptomatology, and Screen for Child Anxiety-Related Emotional Disorders (SCARED). Adverse effects were assessed via chart documentation. RESULTS: Patients were treated with a mean citalopram dose of 22.4 ± 7.3 mg for 12 weeks. Thirteen patients (76%) had CGI-I scores ≤2: 8 of 12 patients with depression and 5 of 5 patients with an anxiety disorder. The mean time to response was 7.6 ± 3.6 weeks. Additionally, 6 of 8 patients had ≥50% reduction from baseline CDRS-R score, with 3 patients (38%) meeting criteria for remission. Three of 4 patients had a >50% reduction for baseline SCARED-parent score. Overall, adverse effects appeared minor and transient. One patient discontinued citalopram due to intolerable adverse effects, and 1 patient required dose reduction. CONCLUSIONS: Citalopram appears to be effective and well tolerated in this group of children and adolescents with depressive or anxiety disorders and a high degree of comorbidity. Controlled studies in this patient population are indicated.

scholarly journals Clinical Profile and Comorbidity of Obsessive-Compulsive Disorder among Children and Adolescents: A Cross-Sectional Observation in Bangladesh

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Md. Hafizur Rahman Chowdhury ◽  
Mohammad S. I. Mullick ◽  
S. M. Yasir Arafat
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Large Scale ◽  
Obsessive Compulsive ◽  
Cross Sectional ◽  
Tic Disorder ◽  
Compulsive Disorder ◽  
Study Results ◽  
Mental Acts ◽  
Age Range

Obsessive compulsive disorder (OCD) is a common disorder characterised by persistent and unwanted intrusive thoughts, images, and urges and repetitive behaviours or mental acts and can cause pervasive impairments. In Bangladesh, the prevalence of OCD among children is 2% which is higher than in previous reporting. This study was aimed at looking into the type, frequency, and severity of symptoms of OCD and comorbidity among children and adolescents. A consecutive 60 OCD cases from a child mental health service with age range of 5–18 years were recruited and divided into below and above 12 years of age group. The assessment was carried out using standardized Bangla version of Development and Wellbeing Assessment and Children’s Yale-Brown Obsessive Compulsive Scale was administered. Of the obsession, contamination was the highest followed by doubt, and of the compulsion, washing/cleaning was the highest followed by checking, repeating, and ordering rituals. More than half of the subjects had severe OCD and comorbidity was present in 58% subjects. Specific phobia, social phobia, major depressive disorder, and tic disorder were more prevalent. These symptoms and comorbidity profile can serve the baseline data for a country like Bangladesh and further large scale study would better generalize the study results.

scholarly journals Dietary knowledge Among Female Diabetic Patients in Amman, Jordan

2016 ◽  
Vol 4 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Jafar El-Qudah
Keyword(s):  
Blood Sugar ◽  
Positive Family History ◽  
Education Programme ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Degree Relative ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Dietary Recall ◽  
Dietary Knowledge

The aim of this study was to assess dietary knowledge among females with diabetes in Amman, Jordan. We performed a cross-sectional study of diabetic patients attending outpatient diabetes clinics, at several hospitals in Amman . A questionnaires and 24-hour dietary recall were completed by the participants. The study used a face to face interview during which a questionnaire was filled by the investigator about knowledge and attitudes of diabetic patients. The study sample was composed of 180 females. Most of the patients have diabetes for more than two years (78.3%) and had a positive family history of diabetes as a first degree relative. About 50% suffered from diabetes related health disease and about half of the patients were overweight and 32.2% were obese. More than half of patients (56.1%) gave wrong answers for meals recommended for diabetes/day and that should be used with hypoglycemia (44.5%), food rich in protein (47.6%), number of snacks (50.6%) and their role (43.1%), drinks permitted with unlimited amounts (61.4%) and suitable time to drink juice (78.1%). Most of the patients gave correct answers for food rich in fats (48.4%), cholesterol (47.8%), and controlling blood sugar (51.7%), right and number of snacks recommended (68.7%) and food which raises blood sugar (49.1%). According to the results, the dietary knowledge of diabetic patients is inadequate and need improvement. The study recommends that there is a need to set up a health education programme on diabetes mellitus which would also include a self-monitoring programme.

Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas

Gut ◽  
2019 ◽  
Vol 69 (2) ◽  
pp. 304-310 ◽  
Author(s):  
Siew C Ng ◽  
Moe Htet Kyaw ◽  
Bing Yee Suen ◽  
Yee Kit Tse ◽  
Martin C S Wong ◽  
...  
Keyword(s):  
Family History ◽  
Colorectal Neoplasms ◽  
Colorectal Neoplasia ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Advanced Adenoma ◽  
Degree Relative ◽  
Cross Sectional ◽  
History Of ◽  
Advanced Adenomas

ObjectiveThe risk associated with a family history of non-advanced adenoma (non-AA) is unknown. We determined the prevalence of colorectal neoplasms in subjects who have a first-degree relative (FDR) with non-AA compared with subjects who do not have an FDR with adenomas.DesignIn a blinded, cross-sectional study, consecutive subjects with newly diagnosed non-AA were identified from our colonoscopy database. 414 FDRs of subjects with non-AA (known as exposed FDRs; mean age 55.0±8.1 years) and 414 age and sex-matched FDRs of subjects with normal findings from colonoscopy (known as unexposed FDRs; mean age 55.2±7.8 years) underwent a colonoscopy from November 2015 to June 2018. One FDR per family was recruited. FDRs with a family history of colorectal cancer were excluded. The primary outcome was prevalence of advanced adenoma (AA). Secondary outcomes included prevalence of all adenomas and cancer.ResultsThe prevalence of AA was 3.9% in exposed FDRs and 2.4% in unexposed FDRs (matched OR (mOR)=1.67; 95% CI 0.72 to 3.91; p=0.238 adjusted for proband sex and proband age). Exposed FDRs had a higher prevalence of any adenomas (29.2% vs 18.6%; mOR=1.87; 95% CI 1.32 to 2.66; p<0.001) and non-AA (25.4% vs 16.2%; mOR=1.91; 95% CI 1.32 to 2.76; p=0.001). A higher proportion of exposed FDRs than unexposed FDRs (4.3% vs 2.2%; adjusted mOR=2.44; 95% CI 1.01 to 5.86; p=0.047) had multiple adenomas. No cancer was detected in both groups.ConclusionA positive family history of non-AA does not significantly increase the risk of clinically important colorectal neoplasia. The data support current guidelines which do not advocate earlier screening in individuals with a family history of non-AA.Trial registration numberNCT0252172.

Nocturnal enuresis among children in Morogoro region in Tanzania: A cross-sectional survey

2020 ◽  
Vol 31 (1) ◽  
pp. 16-29
Author(s):  
Nehemia Kilongo ◽  
Francis F. Furia
Keyword(s):  
Family History ◽  
Demographic Data ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
African Region ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Childhood Disorders ◽  
Factors Affecting ◽  
History Of

Background: Enuresis is common childhood disorders which affecting quality of life of children and causing significant psychosocial disturbances to children and their families. This condition has been widely reported globally with increasing data from sub-Saharan African region. In Tanzania there is no reports on its magnitude and therefore this study was carried out with the aim of determine the prevalence of this condition among children in Tanzania.Methods: This was a community based cross-sectional study conducted among children aged between 5 and 14 years recruited from 12 streets in Morogoro Municipality in Tanzania. Standardized Swahili questionnaire was used to collect data including socio-demographic details of parents,  children and presence of enuresis. Socio-demographic data included age of the child, sex, level of education of the parents, education of the child, presence of bed wetting, history of enuresis in the family.Results: Five hundred and ten children were recruited into this study out of which 271 (53.1%) were females and mean age of study participants was 9±2.8 years. Enuresis was noted in 19% (97/510) of children, 68% (66/97) and 32% (31/97) had primary and secondary enuresis respectively. Significantly higher prevalence rates of enuresis were noted for children aged below 8 years 26.4% (43/162) and those with family history of enuresis 47% (18/38) with p values of 0.01 and < 0.001 respectively. Forty-one (42.3%) out of 97 respondents whose children had enuresis reported to have punished their children and only 21.4% (20/97) reported to have sought treatment for their children.Conclusions: Enuresis is common among children in Tanzania particularly those with positive family history. Punishment to children with enuresis was noted in this study and only one in five parents/guardians sought treatment for their affected children. Therefore, there is a need for initiatives for raising community awareness about enuresis in Tanzania Key words: Enuresis in children, prevalence of enuresis in Tanzania, factors affecting enuresis in children.

scholarly journals The Epidemiological Assessment of Lifestyle Impact on Childhood and Adolescence Psychiatric Disorders in Kohgiloyeh and Boyer-Ahmad Province, Iran

2020 ◽  
Vol 21 (9) ◽  
Author(s):  
Rahim Ostovar ◽  
Nourrollah Yadegari ◽  
Mohammad Reza Mohammadi ◽  
Ali Khaleghi ◽  
Seyed-Ali Mostafav ◽  
...  
Keyword(s):  
Mental Health ◽  
Children And Adolescents ◽  
Psychiatric Disorders ◽  
Weight Control ◽  
Demographic Data ◽  
Well Being ◽  
P Value ◽  
Childhood And Adolescence ◽  
Cross Sectional ◽  
Children And Adolescent

Background: Children and adolescents are potentially at risk of different psychiatric disorders, and it is important to consider their health, especially their mental health. Objectives: We aimed to design a cross-sectional study to investigate the association between lifestyle-related components with the psychiatric disorders in children and adolescents in Kohgiloyeh and Boyer-Ahmad province (Iran) and to determine its association with different lifestyle-related variables. Methods: In this study, about 1000 children and adolescents aged 6 to 18 years in Kohgiloyeh and Boyer-Ahmad province were selected using stratified cluster random sampling. The reliable Persian version of Kiddie-Sads-Present and Lifetime Version (K-SADS-PL) and the Life Style Questionnaire (LSQ) were instructed using interviewing with participants by our clinical psychologists or, if they were under 14 years, with their parents. Besides, demographic data (i.e., gender, age, location, race, nation, and religion) of participants were also collected. Results: The results showed that, except for the physical activity and well-being, other remaining factors have a significant correlation with psychiatric disorders (P < 0.05). The exact p-value for each factor was as follow: physical health (P = 0.007), sports and well-being (P = 0.057), weight control and nutrition (P = 0.001), prevention of diseases (P = 0.04), mental health-cognitive (P = 0.05), spiritual health (P = 0.008), social health (P = 0.05), drug avoidance (P = 0.001), accident prevention (P = 0.02), and environmental health (P = 0.001). Also, we found that the overall effect of lifestyle was significantly associated with children and adolescent mental disorders (P < 0.05). Conclusions: Our findings show a significant role for lifestyle in the children and adolescents psychiatric disorders. So it should be considered in more detail in future studies.

scholarly journals Frequency of Obsessive-Compulsive Disorder and Its Patterns in Families of Children with OCD in Rafsanjan, 2016

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Parvin Agha Mohammad Hasani ◽  
Mohammadreza Mokhtaree ◽  
Mohammad Nazer ◽  
Mohammad Reza Mirzaei
Keyword(s):  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Cross Sectional Study ◽  
Obsessive Compulsive ◽  
Chi Square ◽  
Cross Sectional ◽  
Compulsive Disorder ◽  
Chi Square Test ◽  
Genetic And Environmental Factors ◽  
Level Of Significance

Background: Obsessive-compulsive disorder (OCD) is one of the common psychiatric disorders among children and adolescents that can be created by both genetic and environmental factors. Objective: The present study aimed to evaluate the frequency of OCD and its patterns in families with OCD children. Methods: In this cross-sectional study, 95 children and adolescents with OCD who were referred to the Psychology Clinic of Rafsanjan, Iran, in 2016 were enrolled by a convenience sampling method. The research tool was an obsessive-compulsive questionnaire (children form), and interviews were also carried out with the patients to find the deterioration of the symptoms in them and/or their families. Data were presented and analyzed by mean ± SD, frequency, and Chi-square test. The level of significance was 0.05. Results: The highest frequency of OCD patterns was washing, Checking, and doubt. 36.7% of fathers and 56.1% of mothers had one of obsessive-compulsive disorder patterns. Meanwhile, the most common pattern observed in the parents was cleaning. In total, 79.6% of the paternal families and 87.7% of the maternal families of the patients had OCD. Moreover, a significant relationship was observed in the levels of OCD between children and mothers (P = 0.027), whereas no significant association was detected between the OCD of children and that of their parents. Conclusions: Family history (especially maternal family) plays a significant role in OCD development, which is indicative of the transmission pattern of multifactorial traits, while the heritability of OCD is still not determined.

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