EFFICACY OF COMBINATION OF VITAMIN B1, B6 AND B12 IN MANAGEMENT OF DIABETIC PERIPHERAL NEUROPATHY

2021 ◽  
pp. 54-55
Author(s):  
Abhishek Raj ◽  
Awadhesh Kumar Jha ◽  
Debarshi Jana
Keyword(s):  
Peripheral Neuropathy ◽  
Diabetic Peripheral Neuropathy ◽  
Vitamin B6 ◽  
Rating Scale ◽  
Vitamin B1 ◽  
Pain Rating ◽  
Medical College ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale

Aim: To determine the efcacy of combination of vitamin B1, B6 and B12 in the management of diabetic peripheral neuropathy. Methods: Patients of diabetes mellitus with diabetic peripheral neuropathy were selected from Department of Medicine, Govt. Medical College and Hospital, Bettiah, W. Champaran, Bihar and study done at Pharmacology Department of GMC, Bettiah, W. Champaran, Bihar. The duration of study was six months from March 2019 to August 2019. Patients were prescribed Tab Neurobion (vitamin B1 100mg, vitamin B6 100mg, Vitamin B12 200mcg) twice a day for a period of 4 weeks (28 days). Follow up visit was scheduled on 28th day of the initial visit. Efcacy was judged by documenting improvement in pain of at least 2 points from the baseline as assessed by numeric pain rating scale. Mean age of the patients was observed Results: 46.7±8.6 years. Out of 310 cases, 177 patients (57.0%) were male and remaining 133 patients (43.0%) were female. Duration of diabetes as follows: 83 patients (26.8%) had duration of 0-10 year, 139 patients (44.8%) had 11-20 year, 77 patients (24.8%) had 21-30 year and 11 patients (3.6%) had >30 years of duration. Combination of vitamin B1, B6 and B12 in the management of diabetic peripheral neuropathy was found to be efcacious in 271 patients (87.4%). Treatment with combination of vitamin B1, B6 and B12 Conclusion: appeared to improve pain relief among patients with diabetic peripheral neuropathy.

scholarly journals Evaluation of full cup test and numeric pain rating scale in the assessment of orofacial pain

2021 ◽  
Vol 7 (4) ◽  
pp. 292-295
Author(s):  
Roland Prethipa P ◽  
Jimsha V K ◽  
Jonathan Daniel M
Keyword(s):  
Pain Assessment ◽  
Rating Scale ◽  
Orofacial Pain ◽  
Study Data ◽  
Self Report ◽  
P Value ◽  
Pain Rating ◽  
Cross Sectional ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale

Pain intensity is a common outcome domain assessed in pain clinical trials. The patient’s self-report is the gold standard and it appears to be embedded in everyday clinical practice. Most often pain assessment is considered to be the cornerstone for ideal treatment.The aim of this study was to assess the dental patients’ level of pain using Full Cup Test (FCT) and Numeric Pain Rating Scale (NPRS), and to compare and validate the Full Cup Test in the assessment of orofacial pain with Numeric Pain Rating Scale.A total of sixty patients presenting with various forms of orofacial pain were included in this cross-sectional study. Data collected include the patient demographic details and the diagnosis of each case was made after proper history taking, clinical examination and radiographic investigation. Pain assessment was done for each patient using both numeric pain rating scale and full cup test.All the data were analysed using inferential statistics Mann Whitney test and the analysis was carried out with SPSS 17.The comparison of mean pain scores using full cup test and numeric pain rating scale shows there was significant differences between acute and chronic pain with P- value of 0.023 and 0.005 respectively. FCT had shown 83 percent sensitivity and 94 percent specificity.Patients who presented with either acute or chronic dental conditions experienced moderate to severe level of pain. FCT is useful for both evaluating and discerning changes in pain and it can be used as a tool in pain assessment.

scholarly journals A De Quervain-féle tendinopathia kezelése konzervatív módszerekkel

2020 ◽  
Vol 161 (11) ◽  
pp. 419-424
Author(s):  
László Földvári-Nagy ◽  
Johanna Takács ◽  
Judit Réka Hetthéssy ◽  
Ágnes Andrea Mayer ◽  
Noémi Szakács ◽  
...  
Keyword(s):  
Rating Scale ◽  
Outcome Measure ◽  
Pain Rating ◽  
De Quervain ◽  
Numeric Pain Rating Scale ◽  
Microsoft Office ◽  
Pain Rating Scale

Absztrakt: Bevezetés: A De Quervain-féle tendinopathia a csukló-kéz régióját érintő betegség. A hüvelykujj mozgatása fájdalmassá válik, a kéz funkciója jelentősen romlik. A betegség a legújabb kutatások szerint inkább degeneratív, semmint gyulladásos eredetű. Első lépésként a kéz sínezése, nemszteroid gyulladáscsökkentő szerek és különböző fizikoterápiás kezelések alkalmazása javasolt. Hatástalanságuk esetén további lehetőség az ínhüvelybe fecskendezett szteroidinjekció és a műtéti úton végzett ínhüvelybemetszés. Célkitűzés: Kutatásunkban megvizsgáltuk, hogy az excentrikus tréninggel kibővített konzervatív kezelés megfelelő alternatíváját nyújthatja-e a jelenleg elfogadott kezelési lehetőségeknek. Módszer: Az excentrikus tréning 8 hétig tartott, melyet indokolt esetben 12 hetesre bővítettünk. A betegek (n = 9) a betanítást követően naponta többször végezték a tréninget, amit a heti találkozók alkalmával kontrolláltunk. Az 1., a 8., valamint a 12. heti találkozó során az inspekciót követően mértük az ízületi mozgástartományt, az izomerőt, a fájdalmas régiók számát, illetve elvégeztük a ’Numeric Pain Rating Scale’, a ’Quick Disabilities of the Arm, Shoulder and Hand’, valamint a ’Patient-Rated Wrist Evaluation’ kérdőívek felvételét. A méréseket páros mintás t-teszttel és ismételt méréses varianciaanalízissel elemeztük. Az elemzéseket IBM SPSS Statistics 25.0 és Microsoft Office Excel Professional Plus 2016 programmal végeztük; p<0,05 esetén tekintettük statisztikailag szignifikánsnak eredményeinket. Eredmények: Szignifikáns javulást mértünk a fájdalom intenzitása (’Numeric Pain Rating Scale’ p = 0,005, n = 9) és a kéz, valamint a csukló funkciója terén (’Quick Disabilities of the Arm, Shoulder and Hand Outcome Measure’ kérdőív 1. rész p<0,001, 2. rész p<0,001, ’Patient-Rated Wrist Evaluation’ kérdőív p<0,001; n = 9). Következtetés: Eredményeink alapján megfelelő betegbeválasztás mellett az excentrikus tréninggel kibővített konzervatív kezelés valós alternatívája lehet a jelenleg alkalmazott kezeléseknek. Orv Hetil. 2020; 161(11): 419–424.

scholarly journals Responsiveness of pain, functional capacity tests, and disability level in individuals with chronic nonspecific low back pain

2019 ◽  
Vol 40 (01) ◽  
pp. 11-17 ◽  
Author(s):  
Prasert Sakulsriprasert ◽  
Roongtiwa Vachalathiti ◽  
Pathaimas Kingcha
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Functional Capacity ◽  
Rating Scale ◽  
Low Back ◽  
Pain Rating ◽  
Sit To Stand ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale ◽  
Disability Level

Background: Clinical outcomes are very important in clinical assessment, and responsiveness is a component inside the outcome measures that needs to be investigated, particularly in chronic nonspecific low back pain (CNSLBP). Objective: This study aimed to investigate the responsiveness of pain, functional capacity tests, and disability in individuals with CNSLBP. Methods: Twenty subjects were assessed in pain using the following methods: visual analog scale (VAS) and numeric pain rating scale (NPRS), functional capacity tests: functional reach test (FRT), five-time sit-to-stand test (5 TSST), and two-minute step test (2 MST), and disability level: modified Oswestry Disability Questionnaire (MODQ), Thai version before and after 2-week intervention session. For interventions, the subjects received education, spinal manipulative therapy, and individual therapeutic exercise twice a week, for a total of two weeks. The statistics analyzed were change scores, effect size (ES), and standardized response mean (SRM). Results: The most responsive parameter for individuals with CNSLBP was pain as measured by numeric pain rating scale (NPRS) (ES [Formula: see text]0.986, SRM [Formula: see text]0.928) and five-time sit-to-stand test (5 TSST) (SRM [Formula: see text]0.846). Conclusion: This study found that NPRS pain and 5 TSST were responsive in individuals with CNSLBP at two weeks after the beginning of interventions.

scholarly journals PENGARUH WILLIAM FLEXION EXERCISE TERHADAP PENURUNAN INTENSITAS NYERI HAID (DYSMENORRHEA) PADA SISWI SMAN 7 KOTA MALANG

2019 ◽  
Vol 9 (1) ◽  
pp. 39
Author(s):  
Jaenal Abidin ◽  
Supriyadi Supriyadi ◽  
Mulyani Surendra
Keyword(s):  
Rating Scale ◽  
Sampling Technique ◽  
Control Group ◽  
Pain Rating ◽  
Menstrual Pain ◽  
Control Group Design ◽  
Group Design ◽  
Equivalent Control ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale

AbstrakTujuan penelitian ini untuk mengetahui pengaruh William Flexion Exerciseterhadap penurunan intensitas nyeri haid. Penelitian ini menggunakan rancanganeksperimen semu dengan desain non equivalent control group design. Populasi dalampenelitian ini adalah seluruh siswi kelas XI SMAN 7 Kota Malang yang mengalaminyeri haid yang berjumlah 143 orang. Sampel yang diambil 20 orang untuk masingmasingkelompok. Teknik pengambilan sampel menggunakan purposive sampling.Instrumen yang digunakan yaitu Numeric Pain Rating Scale (NPRS). Hasil ujiANOVA diperoleh nilai p = 0,006. Berdasarkan hasil analisis data dapat disimpulkanbahwa terdapat pengaruh William Flexion Exercise terhadap penurunan intensitasnyeri haid (Dysmenorrhea) antara kelompok eksperimen dan kelompok kontrol padasiswi SMAN 7 Kota Malang.Kata Kunci: nyeri haid, william flexion exerciseAbstractThe purpose of this study was to determine the effect of william flexion exerciseon decreasing the intensity of menstrual pain. This study used quasy experimentaldesign with a non equivalent control group design. The population in this study wereall XI of SMAN 7 Malang City who experienced 143 people. Samples were taken by 20people for each group. The sampling technique used purposive sampling instrument.Used is the Numeric Pain Rating Scale (NPRS). ANOVA test results obtained values p= 0,006. Based on the reluts of data analysis it can be concluded that there are in theinfluence of william flexion exercise on the decrease in menstrual pain intensity(Dysmenorrhea) between control group on female students of SMAN 7 Malang City.Keywords: dysmenorrhea, william flexion exercise

scholarly journals Efficacy of Vitamin B1, B6, and B12 Forte Therapy in Peripheral Neuropathy Patients

2021 ◽  
Vol 2 (1) ◽  
pp. 14-19
Author(s):  
Meyvita Silviana ◽  
Dodik Tugasworo ◽  
Maria Belladonna
Keyword(s):  
Peripheral Neuropathy ◽  
Rating Scale ◽  
Vitamin B1 ◽  
Wilcoxon Test ◽  
Nutritional Deficiencies ◽  
Once Daily ◽  
Tunnel Syndrome ◽  
Michigan Neuropathy Screening Instrument ◽  
Post Hoc ◽  
Pain Rating Scale

Background: Peripheral neuropathy can be caused by diabetes mellitus, nutritional deficiencies, entrapment or Carpal Tunnel Syndrome (CTS), and idiopathic.Objective: To determine the therapeutic efficacy of Vitamin B1, B6, and B12 forte in relieving symptoms of peripheral neuropathy.Methods: This was pre- and post-experimental study involving patients with moderate peripheral neuropathy (Toronto Clinical Neuropathy Score [TCNS] ≥6 and Michigan Neuropathy Screening Instrument [MNSI] ≥7) taken from outpatient neurological clinic of Dr. Kariadi Hospital, Semarang. The patient was prescribed Vit B1 100 mg, B6 100 mg, and B12 5000 mcg once daily for 2 months. Evaluation of the numerical pain rating scale in the form of VAS and Total Symptom Score (TSS) was conducted at the first and second month. The VAS score difference test was conducted with the Wilcoxon test and TSS with the Post Hoc test and considered significant if p <0.05.Results: There were 30 patients aged 18 - 65 years, consisted of 70% female and 30% male. The etiology of peripheral neuropathy were idiopathic (40%), CTS (26.7%), DM (23.3%), and HNP (10%). There were significant differences of the VAS scale  and TSS at every evaluations.Conclusion: Administration of VitB1, B6, and B12 forte relieved symptoms of moderate peripheral neuropathy with improvement of VAS and TSS scores

scholarly journals EFFECTIVENESS OF CERVICAL MANUAL MOBILIZATION TECHNIQUES VERSUS STRETCHING EXERCISES FOR PAIN RELIEF IN THE MANAGEMENT OF NECK PAIN

2021 ◽  
Vol 12 (3) ◽  
pp. 261-264
Author(s):  
Nida Waheed ◽  
Muhammad Amir ◽  
Rabia Noureen ◽  
Sumaira Nawaz ◽  
Raza Zaidi Syeda Wajeeha
Keyword(s):  
Neck Pain ◽  
Rating Scale ◽  
Pain Rating ◽  
Pain Disability Index ◽  
Pain Disability ◽  
Strengthening Exercises ◽  
History Of ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale ◽  
Stretching Exercises

Introduction. A huge literature is available regarding the efficacy of various physiotherapy techniques for neck pain (NP), however, comparative study is still in scarcity. Therefore, this study aimed to compare effectiveness of stretching exercises versus manual mobilization techniques in the management of NP. Material and method. A randomized controlled trial parallel-group design study was conducted on the patients suffering from NP. Participants with the history of NP, aged between 19 to 60 years, NP without radiculopathy, and no history of trauma were included in the study. Two outcome measures were used i.e., Numeric pain rating scale (NPRS) and neck pain disability index (NDI) questionnaire. Two groups were equally divided had twenty-five patients each. Group A received cervical stretching with strengthening exercises as home-treatment program and group B received manual mobilization with strengthening exercises as home-treatment program. Six sessions were given on alternate basis and assessed pre- and post-treatment information of all patients. Results and discussions. Independent sample t-test was run to compare the post difference between stretching exercises and manual mobilization at 95% confidence interval (p<0.05). The Post NPRS difference between the groups shows no significant improvement (p=0.32). Similarly no significant difference was found in post NDI Disability (p=0.57). Therefore, both the treatment strategies are equally effective in improving NP and disability. Conclusions. This clinical trial concluded that stretching or manual mobilization is equally effective to reduce pain and disability. Hence, improve the quality of life in neck pain survivors. Keywords: Manual Mobilization Technique, Neck Pain, , Neck Pain Disability Index Questionnaire, Numeric Pain Rating Scale, Range of Motion, Stretching Exercises,

Platelet-rich plasma for treatment of chronic proximal hamstring tendinopathy

2020 ◽  
Vol 15 (4) ◽  
pp. 1509-1518
Author(s):  
Michael J Auriemma ◽  
Adam S Tenforde ◽  
Adam Harris ◽  
Kelly C McInnis
Keyword(s):  
Functional Outcomes ◽  
Rating Scale ◽  
Platelet Rich Plasma ◽  
Symptom Duration ◽  
Post Intervention ◽  
Reduction Of Pain ◽  
Numeric Pain Rating Scale ◽  
Pain Rating Scale ◽  
Proximal Hamstring

Aim: To determine whether platelet-rich plasma (PRP) can successfully treat symptoms associated with proximal hamstring tendinopathy. Materials & methods: Charts were retrospectively reviewed of patients with a diagnosis of chronic proximal hamstring tendinopathy who underwent an ultrasound-guided leukocyte-rich PRP injection to assess reported outcomes at baseline and final follow-up post-intervention. Results: In 22 patients with a mean age of 48.7 years and mean symptom duration of 26.5 months, mean Numeric Pain Rating Scale and Victorian Institute of Sport Assessment Scale for Proximal Hamstring Tendinopathy subscores demonstrated statistically significant improvements (p < 0.05) at a mean of 7.91 months follow-up. Sixty-eight percent of patients demonstrated ≥50% reduction of pain. Conclusion: Pain and functional outcomes improved following injection of PRP.

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