ROLE OF VESTIBULAR EVOKED MYOGENIC POTENTIALS (VEMP) IN PREDICTING THE OUTCOME OF STAPEDOTOMY- A PROSPECTIVE OBSERVATIONAL STUDY

2021 ◽  
pp. 60-62
Author(s):  
Thirunavukarasu Palanisamy ◽  
Sathishkumar Jayagandhi ◽  
Somu Lakshmanan ◽  
Ajaykumar Prabakar ◽  
Arthi Arun ◽  
...  
Keyword(s):  
Observational Study ◽  
Pure Tone ◽  
Tertiary Care ◽  
Linear Acceleration ◽  
Vestibular Evoked Myogenic Potentials ◽  
Care Hospital ◽  
Non Invasive ◽  
Pure Tone Audiogram ◽  
The Mean

Vestibular evoked myogenic potentials (VEMP) is an objective and non-invasive measure of saccule function that primarily respond to linear acceleration in any direction. Stapedotomy is a procedure done for otosclerosis to improve hearing. The aim of this study was to correlate the VEMPresults with pure tone audiogram pre- and post- stapedotomy in otosclerotic patients. Aprospective observational study was conducted from 2017-2020 in a tertiary care hospital of south India. Patients who underwent stapedotomy for otosclerosis and satised the study criteria were included. Atotal of 22 patients were included in the study. All patients underwent pure tone audiogram (PTA) and VEMP preoperatively and postoperatively. The results were compared and analysed. The mean pre-operative and post-operative ABG were 26.32±9.36 dB and 18.10 ±8.06 dB respectively. (P=0.001). There was no signicant change in VEMP positivity rates, latency and amplitude. The results showed that there was no correlation between the PTAvalues and VEMPpositivity rate in otosclerotic patients. The VEMPpositivity rate was also not affected signicantly by stapedotomy. Based on above ndings we conclude that stapedotomy is a safe and effective procedure with no signicant inner ear trauma.

scholarly journals Role of platelet distribution width and plateletcrit in assessment of nonthrombocytopenic preeclampsia and eclampsia in a tertiary care hospital of Odisha: an observational study

2020 ◽  
Vol 9 (5) ◽  
pp. 1996
Author(s):  
Kirtirekha Mohapatra ◽  
Pranati Mohanty ◽  
Nahida Nigar Sultana
Keyword(s):  
Platelet Count ◽  
Observational Study ◽  
Severe Disease ◽  
Tertiary Care ◽  
Measurement Tool ◽  
Care Hospital ◽  
Platelet Distribution Width ◽  
Distribution Width ◽  
Platelet Indices

Background: Preeclampsia (PE) is a major cause of maternal and foetal morbidity and mortality in pregnancy. A decreased platelet count is observed during the progression of preeclampsia, and is considered a marker of the severity of preeclampsia. Considering the role of the PDW, PCT and platelet indices during the disease, the aim of this study was to evaluate the feasibility of using platelet indices as a severity marker for PE.Methods: This was a prospective, observational study, hospital-based study, from 2017-19 with 400 pregnant women being included on the basis of a predefined inclusion and exclusion criteria, through antenatal clinic, and labour room of the department of obstetrics and gynecology, S. C. B. Medical College, Cuttack, Odisha, India.Results: Study found that platelet count and plateletcrit showed a significant negative correlation with MAP whereas platelet distribution width showed a maximum positive correlation. In the preeclampsia group, subjects with PCT <0.22% were at risk of developing severe disease with a sensitivity of 53.5% and a high specificity of 85.5%. The AUC of 0.75 showed that it has a good predictability. In the eclampsia group, subjects with PCT <0.16% had a risk of developing severe disease with a sensitivity of 89.5% and specificity of 73.7%. The AUC 0.9 shows PCT to be a good predictor for assessing severity of eclampsia.Conclusions: This study suggests that platelet distribution width and plateletcrit are useful in risk evaluation of preeclampsia. These are a valid measurement tool to predict the severe progression of PE even when normal platelet counts are observed.

scholarly journals Aspergillus spp. infection as a cause of acute exacerbations of chronic obstructive pulmonary disease: a prospective observational study

2019 ◽  
Vol 7 (5) ◽  
pp. 1604
Author(s):  
Lashmipriya S. ◽  
Ravindran Chetambath ◽  
Amitha Sunny ◽  
Sanjeev Shivashankaran ◽  
Muhammed Aslam
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
Aspergillus Infection ◽  
Acute Exacerbations

Background: Majority of exacerbations of COPD (AECOPD) are due to infections. Usual agents causing AECOPD are gram negative bacteria, but rarely viruses and fungi are also implicated. However, the role of fungal infection, especially Aspergillus spp. in the clinical deterioration of COPD still remains unclear. This prospective observational study looks at the prevalence of aspergillus infection in AECOPD. The Objectives of this study were to analyse the prevalence and risk factors associated with Aspergillus infection in AECOPD, and to investigate the clinical outcomes.Methods: Patients admitted with AECOPD for a period of 3 months from 1st October 2017 to 31st December 2017 were prospectively included from ICU and general ward of Pulmonary Medicine department of a tertiary care hospital. Clinical, radiological and microbiological data were collected at admission and during the hospital stay. Clinical course and outcome are recorded.Results: There were 104 cases of AECOPD during the study period out of which 96 were males and 8 were females. 17 patients had evidence of aspergillus infection and diabetes was found to be an independent risk factor for aspergillus infection.Conclusions: Aspergillus infection is an important cause of COPD exacerbation and this is directly related to diabetes mellitus.

scholarly journals THE PREVALENCE AND CLINICAL PROFILE OF PATIENTS PRESENTED WITH POSTERIOR FOSSA EXTRA DURAL HEMATOMA IN TERTIARY CARE HOSPITAL: A RETROSPECTIVE OBSERVATIONAL STUDY.

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Deepak Karn
Keyword(s):  
Observational Study ◽  
Posterior Fossa ◽  
Early Recognition ◽  
Tertiary Care ◽  
Postoperative Outcome ◽  
Clinical Profile ◽  
Retrospective Observational Study ◽  
Care Hospital ◽  
The Mean ◽  
Admission Glasgow Coma Scale

Aim: to determine the prevalence and clinical profile of patients presented with posterior fossa extra dural hematoma. Materials and Methods: The present retrospective observational study was conducted in the Department of Neurosurgery, SKMCH, Muzaffarpur, Bihar, India.  The records were retrospectively analyzed for clinical presentation, admission Glasgow Coma Scale (GCS), mode of injury, type of intervention and postoperative outcome. Outcomes were assessed on the basis of Glasgow Outcome Score (GOS) at the time of discharge and at 3 months Results: Of these 39 patients, 28 were males and 11 females. The mean age of patients was 29.21 years. 24 patients had GCS 13-15 at admission followed by 9 with GCS 9-12 and only 5 of them had GCS <9 at admission. Mean EDH volume was 28.7 ml. 36 patients were operated, 5 patients managed conservatively. Conclusion: The posterior fossa is an uncommon site for epidural haematomas. Due to the small volume of the posterior fossa and contained important structures mortality can be high if the haematoma is missed. Clinical progress is silent and slow, but the deterioration is sudden and quick to become fatal if not promptly treated. Early recognition is extremely important. Keywords: Extradural hematoma, Posteriors fossa, GCS, Trauma

Intramedullary Nailing with Blocking Screws in the Treatment of Fractures of Proximal and Distal Ends of Tibia - A Prospective Observational Study in a Tertiary Care Hospital of Kannur, Kerala

2021 ◽  
Vol 8 (39) ◽  
pp. 3448-3453
Author(s):  
Adnan Siddique P. ◽  
Prateek Chandak M. ◽  
Sasikumar Sasidharan
Keyword(s):  
Observational Study ◽  
Internal Fixation ◽  
Intramedullary Nailing ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Care Hospital ◽  
Distal Fragment ◽  
Intramedullary Nails ◽  
Female Ratio ◽  
The Mean

BACKGROUND Fractures of both proximal and distal metaphyses with small distal fragment of tibia are not uncommon. Internal fixation using intramedullary nails alone could lead to misalignment. Using blocking screws (Poller screws) in addition to intramedullary nails would help in narrowing the medullary cavity and decreases the degree of misalignment and chances of displacement. The present study was conducted to evaluate functional and radiological outcome of blocking screws with intramedullary nail in the treatment of proximal and distal metaphyses fractures of tibia with short distal fragment. METHODS A prospective observational study of 34 patients with proximal and distal tibial metaphyses fractures was treated with statically locked intramedullary nailing with supplementary blocking screws. The study was conducted from January 2018 to December 2020 with a maximum follow up of 18 months. Medullary canal diameter was measured at the levels of fracture and isthmus. RESULTS Among the 34 patients, 29 (85.29 %) were males and 05 (14.70 %) were females with a male to female ratio of 5.8 : 1. The mean age was 34.97 ± 3.10 years. The mean healing period was 20 ± 1.45 weeks. 25/34 (73.52 %) of the patients showed Karlstrom and Olerud functional grading score of excellent. The fracture varus/valgus alignment was 1.9 ± 0.3 degrees. The mean antecurvatum/recurvatum alignment was 0.3 degrees. CONCLUSIONS Blocking screws act as reduction tools, help in reducing the medullary lumen of distal metaphyses and prevent failures in initial reduction. They extend the indication of intramedullary nailing to the distal segment of tibia and minimize the misalignment in terms of varus /valgus and/or antecurvatum/recurvatum. KEYWORDS Tibia, Intramedullary, Blocking Screws, Internal Fixation and Misalignment

scholarly journals AUDIOMETRIC ASSESSMENT IN POST COVID-19 PATIENTS: A CROSS-SECTIONAL STUDY IN A TERTIARY CARE HOSPITAL OF KARACHI - PAKISTAN

2021 ◽  
Vol 71 (Suppl-3) ◽  
pp. S479-83
Author(s):  
Shanila Feroz ◽  
Kausar Mahmood ◽  
Iqbal Hussain Udaipurwala ◽  
Syeda Zain ◽  
Mahveen Iqbal ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Pure Tone ◽  
Tertiary Care ◽  
Sensorineural Deafness ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pure Tone Audiogram

Objective: To assess audiometry investigations in patients having complaint of tinnitus, vertigo or hearing impairment after recovery from COVID-19 disease, having no external or middle ear diseases. Study Design: Cross-sectional study. Place and Duration of Study: United Medical and Dental College, Creek General hospital, Korangi, Karachi Pakistan, from March to May 2021. Methodology: A total of 60 patients were included in this study who had recovered from the primary COVID-19 infection and reported with the complaints of tinnitus, vertigo and hearing loss. Pure tone audiogram was assessed for sensorineural deafness, its severity and frequencies affected. Pearson Chi square test was used to see the relation of symptoms with severity of hearing loss. Results: There were 42 (70%) males and 18 (30%) female patients with age range from 18-50 years with mean age of 28.4 ± 8.1 years. Tinnitus was the most common complaint (83.3%) followed by hearing loss (28.3%) and vertigo (23.3%) patients. None of the patients with complaint of hearing loss had normal pure tone audiogram in either right or left ear (p=0.000). Patients with all the three complaints had more hearing impairment where majority had moderate or severe hearing loss (p=0.000). All patients with isolated complaint of vertigo (9 patients) had normal audiogram in both ears (p=0.000). Conclusion: Auditory and vestibular system involvement in reasonably common in COVID-19 patients. Tinnitus is the most frequent symptom and it should be investigated with full audiological investigations.

scholarly journals Dermatosis of scalp and hair disorder: an observational study in a hilly state of North-East India

2021 ◽  
Vol 7 (5) ◽  
pp. 720
Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das
Keyword(s):  
Observational Study ◽  
Seborrheic Dermatitis ◽  
Critical Role ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
North East India ◽  
North East ◽  
Inflammatory Conditions

<p class="abstract"><strong>Background:</strong> The skin of the scalp has several unique features that aid in its critical role of protecting the head. These unique features of the scalp make it susceptible to superficial mycotic conditions, parasitic infestation and inflammatory conditions. These disease processes of the scalp can have significant overlap in clinical symptomatology. The aim was to observe the clinical profile of scalp dermatosis and hair disorder at a tertiary care hospital.</p><p class="abstract"><strong>Methods:</strong> This was a cross sectional observational study which was carried over a period of 1 year 5 months from August 2019 to November 2020. A total of 76 patients were included in the study, who visited dermatology OPD of SMIMS, Sikkim.<strong></strong></p><p class="abstract"><strong>Results:</strong> This study included 76 patients of clinically and histopathologically diagnosed cases of scalp dermatosis and hair disorder, 47 males and 29 females. A total of 18 different dermatoses were observed in this study. The most common disorder was seborrheic dermatitis, which accounted for 18.4 %, followed by androgenetic alopecia in 17% and alopecia areata in 15% cases in the present study.</p><p class="abstract"><strong>Conclusions:</strong> The article provides an overview of the most common scalp disorders, which we have observed in our study.</p>

scholarly journals FETO-MATERNAL OUTCOME OF CAESAREAN SECTION DURING SECOND STAGE OF LABOR IN A TERTIARY CARE HOSPITAL: AN OBSERVATIONAL STUDY

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Ruby Kumari
Keyword(s):  
Caesarean Section ◽  
Observational Study ◽  
Tertiary Care ◽  
Neonatal Morbidity ◽  
Cervical Dilatation ◽  
Care Hospital ◽  
Maternal Complications ◽  
Second Stage ◽  
Second Stage Of Labour ◽  
The Mean

Aim: To highlights the maternal and neonatal outcome of caesarean section in second stage of labour. Methods: This prospective observational study was carried out in the Department of Obstetrics and Gynecology at Government Medical College and Hospital Bettiah, Bihar, India from December 2017 to December  2018. total of 24600 women delivered by caesarean section, 16800 emergency and 7800 elective cases. Of these 400 were at full cervical dilatation, >37 weeks gestation with a singleton fetus in cephalic presentation. All caesarean sections performed at full cervical dilatation over the time period of 1 year at a government hospital were included. Results: Among the 400 patient’s majority of them were in the age group of 20-30 years (72.5%). about 75.5% of the patients were primigravidae and only the remaining 24.5% were multigravida. The commonest indications for doing caesarean section in the second stage of labour were cephalo pelvic disproportion, fetal distress and obstructed labour. Incidence of PPH is 48 out of 400 cases (12%). Post-operative wound infection was seen in 23(5.75%) and Post-operative fever was seen in 70(17.5%) out of 400 cases. There were no cases of maternal deaths reported. The mean operative time was 52.9 min .The mean length of hospital stays was 6.6 days. Mean weight of the babies of the second stage caesarean section was 3.2 kg. Conclusions: Caesarean sections done in second stage of labour are associated with several intra-operative maternal complications and neonatal morbidity. Keywords: Caesarean complications; emergency caesarean section; maternal morbidity; neonatal morbidity

TO DETERMINE THE ROLE OF CA125 IN THE DIAGNOSIS OF ACUTE APPENDICITIS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta
Keyword(s):  
Acute Appendicitis ◽  
Clinical Diagnosis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Ca 125 ◽  
Care Hospital ◽  
Serum Samples ◽  
Roc Curve Analysis ◽  
Surgery Department

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.

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