scholarly journals COMPARATIVE ANALYSIS BETWEEN ULTRASONIC TIPS AND HAND INSTRUMENTS ON THE CLINICAL PARAMETERS OF PERIODONTAL DISEASE.

2020 ◽  
pp. 53-56
Author(s):  
Avadhesh Kumar ◽  
Jaya Dixit ◽  
Nand Lal ◽  
Shalini Kaushal
Keyword(s):  
Periodontal Disease ◽  
Post Treatment ◽  
Clinical Parameters ◽  
Treatment Change ◽  
Pocket Depth ◽  
Plaque Score ◽  
Probing Pocket Depth ◽  
Significant Difference ◽  
Pi Calculus ◽  
Pre Treatment

Aims To compare hand versus ultrasonic scaling and root planning (SRP) on the clinical parameters of periodontal disease and to assess left over calculus by open flap approach. Methods and Material The study sample consisted of random selection of 30 patients with the evidence of chronic inflammatory periodontal disease. Two groups were made in each patient by split mouth design. Pre treatment measurements recorded were plaque index (PI) , calculus index(CI) and probing pocket depth(PPD). Post treatment measurements recorded were PI , PPD and left over calculus after flap elevation Results In hand instrumentation group (HIG),, mean percentage of plaque score was slightly lesser as compared to ultrasonic but not significant.. Overall mean reduction in PPD after instrumentation in HIG was greater as compared to ultrasonic, but it was not statistically significant (p>0.05). The percentage efficiency in removal of calculus of HIG was greater compared to ultrasonic but it was also not statistically significant (p>0.05). There was no significant difference between HIG and ultrasonic for number of sites with residual calculus and moreover no. of sites increased apically. Conclusions There was significant post-treatment change in the clinical parameters taken in the present clinical study in both HIG & UIG and also slightly more favourable with HIG but not statistically significant.

scholarly journals A COMPARATIVE STUDY TO ASSES THE EFFICACY OF NANOBIO FUSION GEL AS AN ADJUNCT TO SCALING AND POLISHING IN CHRONIC PERIODONTITIS. - A CLINICAL STUDY

2020 ◽  
pp. 1-3
Author(s):  
Patil A. Veena ◽  
Ansari T. Sobia ◽  
Agarwal Priyanka ◽  
Ayesha Ayesha ◽  
Sultana Shahnaaz
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Antimicrobial Agents ◽  
Test Group ◽  
Controlled Clinical Trial ◽  
Pocket Depth ◽  
Antioxidant Power ◽  
Probing Pocket Depth ◽  
Significant Difference ◽  
And Control

Introduction: Various chemical agents such as nonsteroidal, anti-inflammatory drugs and antimicrobial agents has gained popularity in treatment of periodontal disease but simultaneously lead to condition such as drug resistance and drug allergy. Hence , the topical application of herbal agents such as propolis, aloevera, green tea extracts, Neem reduces the potency and effectiveness to prevent progression of periodontal disease. NanoBioFusion(NBF)gel contains the natural antioxidant power of propolis,vit C,vit E which allows the ultrafine antioxidant to surpase the moist intraoral environment to enter the cells and rejuvenate,revitalize,support,protect and optimize gum and soft oral tissue.Hence the present study is aimed to evaluate the clinical effect of locally delivered NBF gel as an adjunctive therapy to scaling and polishing in the treatment of Periodontitis. Materials and Methods: Chronic Periodontitis patients with 40 sites and probing pocket depth (PD) between 5 and 7 mm were selected in a randomized controlled clinical trial. SRP was performed in both control and test group followed by NBF gel application in 40 sites. The plaque index, gingival index and probing Pocket depth,were recorded at baseline, 6 weeks, and 3 months.The statistical analysis with paired t‑test was used to compare the test and control sites. Results: From baseline to a period of 3 months, a statistically significant difference was seen between both groups for Pocket probing depth and from baseline to 6 weeks the mean GI and PI score have a statistically significant result was obtained(P=0.01& 0.00). Conclusions: Locally delivered NBF gel exhibited a significant improvement compared with SRP alone in chronic periodontitis.

scholarly journals Folate-receptor 1 level in periodontal disease: a pilot study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Duygu Alkan ◽  
Berrak Guven ◽  
Cigdem Coskun Turer ◽  
Umut Balli ◽  
Murat Can
Keyword(s):  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Folate Receptor ◽  
Serum Folate ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Serum Samples ◽  
Pocket Depth ◽  
Probing Pocket Depth ◽  
Significant Difference

Abstract Background The purpose of this study was to investigate gingival crevicular fluid (GCF) and serum folate-receptor 1 (FOLR1) levels in subjects with different periodontal status. Methods The study consists of three groups: Healthy group (n = 15), gingivitis group (n = 15) and chronic periodontitis group (n = 15). Clinical periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI) and bleeding on probing (BOP) were assessed. GCF and serum samples were collected from each patient and were analyzed FOLR1 levels by enzyme-linked immunosorbent assay. Results The values of FOLR1 in GCF were higher in gingivitis and periodontitis groups than among patient in control group (p < 0.016). Serum FOLR1 levels showed no significant difference between the groups. A significant correlation was observed between FOLR1 levels of GCF and BOP (p < 0.05). Conclusions Our preliminary data suggest that FOLR1 is not useful in monitoring the periodontal disease. Further studies are necessary to clarify the role, regulation and function of folate and it’s receptors in the pathogenesis of periodontal disease.

Salivary Matrix Metalloproteinase-8 (MMP-8) in Relation to Periodontal Health Status Among a Group of Hypertensive Patients

2018 ◽  
Vol 30 (3) ◽  
pp. 48-53
Author(s):  
Iman Z AlMudaris ◽  
Nadia A AlRawi
Keyword(s):  
Periodontal Disease ◽  
Plaque Index ◽  
Control Group ◽  
Study Group ◽  
Periodontal Health ◽  
Pocket Depth ◽  
Clinical Attachment Level ◽  
Probing Pocket Depth ◽  
Significant Difference ◽  
Attachment Level

Background: Hypertension is probably the most important public health problem around the world. People with periodontal disease may be at greater risk of hypertension. The inflammatory effects of periodontal disease help to promote endothelial dysfunction in arteries which may lead to changes in blood pressure. Salivary MMP-8 has been associated with both periodontal disease and prevalent hypertension. Aim of study: This study was conducted to measure salivary matrix metalloproteinase - 8, in relation to periodontal health condition among a group of patients with hypertension in comparison with control group. Materials and methods: Ninety subjects, aged 45-50 years old were included in this study, seeking treatment for chest pain in Ibn-AlBaytar center for cardiac surgical treatments in Baghdad, Iraq. The subjects were divided into study group (45 patient) who were diagnosed to be a hypertensive patient, and a control group (45 subject), with no hypertension. Plaque status was evaluated according to the Silness and Loe, probing pocket depth and clinical attachment level. Unstimulated saliva was collected from all subjects to analyses MMP-8. Result: A high mean value of plaque index, clinical attachment level and probing pocket depth for the study group than the control group with statistically no significant difference. In addition to that, a significant positive correlation between the plaque index and the clinical attachment level among both groups. Salivary MMP-8 level showed a higher level in the study group than in the control group, with statistically significant difference between groups, and a significant positive correlation was detected between salivary MMP-8 with plaque index, among study group, Conclusions: Higher percentage of periodontal diseases was found among patients with blood hypertension. In addition, high level of salivary MMP-8 is potentially associated with periodontal status of the study group.

scholarly journals assessment of periimplant soft tissue condition with morse taper abutment connection

2021 ◽  
Vol 21 ◽  
pp. e224977
Author(s):  
Puspa Puspita Lasminingrum ◽  
Aldilla Miranda ◽  
Dyah Nindita Carolina ◽  
Prajna Metta
Keyword(s):  
Soft Tissue ◽  
Rapid Review ◽  
Clinical Parameters ◽  
Gingival Index ◽  
Literature Searching ◽  
Pocket Depth ◽  
Plaque Score ◽  
Probing Pocket Depth ◽  
Mucosal Thickness ◽  
Assessment Results

Aim: This study aims to evaluate the clinical assessment results of periimplant soft tissue with morse taper (internal abutment connection). Methods: The study was conducted using a rapid review by searching the articles from PubMed NCBI and Cochrane by using keywords. All articles were selected by the year, duplication, title, abstract, full-text, and finally, all selected articles were processed for final review. Following clinical parameters were included; Periimplant Probing Pocket Depth (PPD), Plaque Score (PS), modified Plaque Index (mPI), Mucosal Thickness (MTh), Gingival Height (GH), periimplant mucosal zenith, Pink Esthetic Score (PES), Bleeding On Probing (BOP), Sulcus Bleeding Index (SBI), and modified Gingival Index (mGI). Results: 9 selected articles were obtained from the initial literature searching count of 70 articles. The overall samples included 326 morse taper implants. Based on the evaluation, 3 out of 4 articles reported pocket depth < 4 mm, no bleeding was reported in 2 out of 4 articles. 4 out of 4 articles reported low plaque accumulation, low soft tissue recession was reported in 3 out of 3 articles, and 4 out of 4 articles reported acceptable PES values. Conclusion: The evaluations indicate that the morse taper (internal abutment connection) has favorable assessment results based on various clinical parameters.

Neutrophil Exodus From The Gingival Crevice - A Novel Method of Quantification Using Durapore Filter Strips: A Cross Sectional Study

2011 ◽  
Vol 1 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Sudhindra Kulkarni ◽  
Sachin Kanagotagi
Keyword(s):  
Periodontal Disease ◽  
Critical Role ◽  
Cross Sectional Study ◽  
Special Equipment ◽  
Pocket Depth ◽  
Cross Sectional ◽  
Probing Pocket Depth ◽  
Periodontal Index ◽  
Significant Difference ◽  
Group 2

Abstract Objectives Neutrophils play a critical role as a part of the innate immune response. Although neutrophils are primarily protective, they release products partly responsible for the destruction seen in periodontal disease. The techniques presently available for counting neutrophils require special equipment and are only semi-quantitative. The aim of the present investigation was to check the efficacy of a single, rapid, non-invasive assay to enable the expedient quantification of oral neutrophils, and utilize the assay to quantify the number of neutrophils in periodontal disease. Materials and Methods Forty five subjects were recruited in the study. They were put into three groups based on the Gingival Index and Russell's Periodontal Index as clinically healthy (Group 1), gingivitis (Group 2) and periodontitis (Group 3). GCF samples were collected using a durapore filter and the number of neutrophils counted using an improved Neubaeur's Chamber. Results Neutrophils were present in GCF of all the samples. There was statistically significant difference between the neutrophil numbers in all the samples with respect to severity of periodontal disease. The strength of association was the strongest between probing pocket depth and neutrophil counts. Conclusion This study demonstrates that it is possible to collect and quantify oral neutrophils by a single, rapid, noninvasive assay using durapore strips.

scholarly journals What is the best soft-tissue reference plane to quantify lip change in bimaxillary protrusion cases? A retrospective cohort study

2020 ◽  
Vol 10 ◽  
pp. 178-184
Author(s):  
Mustafa Nasar ◽  
Donald J. Ferguson ◽  
Johnny Joung-Lin Liaw ◽  
Laith Makki ◽  
Nikhilesh R. Vaid
Keyword(s):  
Soft Tissue ◽  
Post Treatment ◽  
Reference Plane ◽  
Treatment Change ◽  
Lower Lip ◽  
Soft Tissue Profile ◽  
Lateral Cephalograms ◽  
Significant Difference ◽  
Pre Treatment ◽  
Bimaxillary Protrusion

Objectives: The objective of the study was to evaluate the validity of five soft-tissue profile planes to actual horizontal lower lip changes following treatment of severe bimaxillary protrusion patients with vertical maxillary excess using extra-alveolar miniscrews. The null hypothesis was no differences in the incremental changes of horizontal lower lip changes from pre-treatment to post-treatment of the five methods compared to actual changes. Materials and Methods: Seventy adults were treated orthodontically with extractions for bimaxillary protrusion and “gummy” smile using extra-alveolar miniscrews. Lower lip horizontal position was assessed with pre- and post-treatment lateral cephalograms and five commonly used soft-tissue reference lines were used to measure horizontal lower lip treatment change. Results: Compared to actual therapeutic lower lip horizontal retraction (4.38 mm), soft-tissue references Ricketts’ E-line (3.89 mm) and Steiner’s S-line (3.88 mm) demonstrated no statistical difference (P > 0.05) from actual change. The five profile plane measures showed moderately high to high intercorrelations among themselves, but none of them were related to the actual amount of anteroposterior lip change that occurred. None of the five soft-tissue measurements showed a statistically significant difference (P > 0.05) between subgroups with least and greatest lower lip retraction. Conclusion: Under conditions of maximum lower lip retraction, Rickett’s E-line and Steiner’s S-line were fair measures of horizontal lower lip change. Although actual lower lip change and soft-tissue reference plane changes were correlated poorly, intercorrelations among the five soft-tissue references planes were moderately high. None of the five soft-tissue measurements was able to discriminate (P > 0.05) between treatments with least and greatest lower lip retraction. It may be concluded that Rickett’s E-line and Steiner’s S-line soft-tissue profile references are valid when there is considerable therapeutic retraction (4+ mm) of the lower lip.

scholarly journals Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Liza L. Ramenzoni ◽  
Deborah Hofer ◽  
Alex Solderer ◽  
Daniel Wiedemeier ◽  
Thomas Attin ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Salivary Glands ◽  
Gingival Crevicular Fluid ◽  
Clinical Parameters ◽  
Pocket Depth ◽  
Active Matrix ◽  
Probing Pocket Depth ◽  
Whole Saliva ◽  
Biomarker Testing ◽  
Crevicular Fluid

Abstract Background Pathologically elevated levels of matrix metalloproteinase-8 (MMP-8) and Lactoferrin in oral fluids have been associated with the presence of gingivitis/periodontitis. This study aimed to assess the origin of MMP-8 and Lactoferrin in periodontitis patients and to identify the degree to which conventional clinical parameters correlate with their presence. Methods A total of ten periodontitis and ten healthy patients were included in this study. Whole saliva (stimulated and unstimulated), parotid/sublingual glandular fluid and gingival crevicular fluid from pockets and sulci were tested for MMP-8 and Lactoferrin and protein concentrations were quantified using an ELISA assay. Clinical parameters were checked for potential associations with MMP-8 and Lactoferrin levels. Results Periodontal patients presented higher concentrations of MMP-8 and Lactoferrin in pockets than other sources (P = 0.03). Lactoferrin measurement was higher in the parotid compared to sublingual glandular fluid in periodontitis patients (P = 0.03). Increased probing pocket depth was positively correlated with high MMP-8 and Lactoferrin levels. Conclusions Periodontal pockets appear to be the major source of active matrix metalloproteinase and Lactoferrin, which also may also enter the oral cavity through the salivary glands. Since clinically healthy sites in periodontitis patients also had elevated biomarker levels, gingival crevicular fluid biomarker testing may be more predictive of future tissue breakdown than conventional clinical parameters.

Association of ALDH2 Genotypes with Periodontitis Progression

2009 ◽  
Vol 89 (2) ◽  
pp. 138-142 ◽  
Author(s):  
N. Nishida ◽  
M. Tanaka ◽  
S. Sekine ◽  
T. Takeshita ◽  
K. Nakayama ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Periodontal Disease ◽  
Disease Progression ◽  
Odds Ratio ◽  
Alcohol Sensitivity ◽  
Pocket Depth ◽  
Probing Pocket Depth ◽  
Significant Odds Ratio ◽  
Progression Risk ◽  
Prospective Association

The progression of periodontitis may be affected by ALDH2 genotypes with respect to the oxidation of acetaldehyde to acetate, which leads to the accumulation of acetaldehyde in plasma and potential toxic effects. We examined the prospective association of ALDH2 genotypes in terms of alcohol sensitivity between alcohol consumption and periodontal disease progression. In 2003, 224 of 256 (87.5%) individuals examined at baseline (1999) completed probing pocket depth measurements for the evaluation of periodontitis progression. Missing data on self-reported questionnaires and blood samples were excluded; therefore, 183 samples were analyzed. Individuals who consumed ≥ 33.0 g/day of alcohol exhibited high periodontal disease progression risk (OR = 3.54). ALDH2 *1/*2 individuals who consumed ≥ 33 g/day of alcohol displayed a significant odds ratio (OR = 4.28) of periodontitis progression risk, in contrast to ALDH2 *1/*1 individuals. These results suggested that alcohol consumption as well as alcohol sensitivity may be a risk factor for periodontitis progression.

scholarly journals Validating gingival surface temperature as an alternative tool in the diagnosis of periodontal disease activity: An observational clinical trial

2019 ◽  
Vol 13 (2) ◽  
pp. 123-127
Author(s):  
Sumanth Gunupati ◽  
Hasya Sappiti ◽  
Sreenivas Nagarakanti ◽  
BV Ramesh Reddy ◽  
Vijay Kumar Chava
Keyword(s):  
Pilot Study ◽  
Periodontal Disease ◽  
Surface Temperature ◽  
Disease Activity ◽  
Diagnostic Tool ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Cross Sectional ◽  
Probing Pocket Depth ◽  
Pilot Clinical Study

Background. Elevated temperature has been recognized as an inflammatory sign. It is the only indication that can be both objectively and quantitatively evaluated and is considered as a potential indicator of periodontal disease. Assessing gingival surface temperature (GST) could be a diagnostic parameter to determine periodontal health. This pilot clinical study aimed to validate gingival surface temperature (GST) as a clinical diagnostic tool to measure periodontal disease activity by correlating with the periodontal inflamed surface area (PISA). Methods. A cross-sectional mono-center pilot study was conducted with a convenient sample of 50 participants with a mean age of 34.14±13.7 years. Clinical parameters such as probing pocket depth (PPD) clinical attachment loss (CAL) and bleeding on probing (BOP) were measured. GST was recorded with a single lead of the bedside patient monitor and correlated with PISA. Results. The results showed a positive correlation between PISA and GST (P=0.46). Conclusion. This study showed a rise in GST of inflamed sites, but the results did not support the hypothesis that increased GST is an indicator of periodontal disease. As this is a pilot study, further studies with more larger sample sizes need to be undertaken to confirm its use as a diagnostic tool in clinical trials.

scholarly journals The Contribution of Cognitive Impulsivity to Criminal Risk

2021 ◽  
Author(s):  
◽  
Rebecca K. Bell
Keyword(s):  
Impulse Control ◽  
Post Treatment ◽  
Trait Anger ◽  
Special Treatment ◽  
Treatment Programme ◽  
Treatment Change ◽  
Anger Control ◽  
Treatment Unit ◽  
Cognitive Behavioural ◽  
Pre Treatment

<p>Impulsivity increases risk for general, violent and sexual offending. Accordingly, helping offenders to become better regulators of their impulses is one goal of offender rehabilitation. In a correctional setting, the assessment of impulsivity focuses on personality and behaviour, but not cognition; cognitive impulse control impairments are inferred from personality styles and behavioural patterns suggestive of acting before thinking. However, empirical findings challenge the validity of inferring cognition from personality and behavioural measures. Additionally, without assessing cognition, practitioners are limited in their ability to isolate which cognitive processes are most impaired and therefore worthy of intervention for individual offenders.  To establish the contribution of cognitive impulse control to criminal risk, a theoretically derived, empirically supported neurocognitive assessment framework was adopted. The framework is based on the notion that impulsive behaviour arises from three, potentially dissociable skill domains that support impulse control: decisionmaking, perceptual and motor impulse control. A cohort of 77 men attending intensive cognitive-behavioural rehabilitation was recruited from four of New Zealand’s prison-based Special Treatment Unit Rehabilitation Programmes (STURPs). A neurocognitive battery of five tasks collectively representing each cognitive impulse control domain was administered before and after the 8-month treatment programme.  Study One explored pre-treatment clinically impaired performance within and across each cognitive impulse control domain. Compared to normative data, performance was typically in the average to below average range, but it was not clinically impaired overall. When performance was clinically impaired, it was most pronounced on tasks requiring cognitive flexibility.  Study Two explored treatment change in cognitive impulse control. The study also compared pre-treatment cognitive impulse control between offenders who went on to complete the treatment programme and those who were prematurely removed for responsivity or conduct-related issues. No pre-treatment cognitive impulse control differences were found between treatment completers and non-completers. Treatment completers displayed small pre-post treatment improvements in some areas of cognitive impulse control, but not others.  Study Three explored cross-sectional and predictive relationships between cognitive impulse control, dynamic criminal risk, trait anger and anger control. Although there was little association between these variables before treatment, some cognitive impulse control outcomes predicted post-treatment dynamic criminal risk, trait anger and anger control. Thus, the evidence suggested that certain aspects of cognitive impulse control might function as facilitators of treatment change.  Together, the findings highlighted the importance of evaluating cognitive impulse control as part of the risk assessment, and clinical formulation process. The findings also suggested that interventions designed to develop cognitive impulse control abilities either before, or as a complement to traditional cognitive-behavioural interventions, have the potential to maximise treatment response.</p>

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