scholarly journals A COMPARATIVE STUDY RELATING WATER DRINKING TEST AND INTRA OCULAR PRESSURE IN DIFFERENT AGE GROUPS

2021 ◽  
pp. 6-8
Author(s):  
Thangerani Raajaseharan ◽  
S.R. Raajaseharan ◽  
Aishwarya Thanasekaran ◽  
Nihma Arif A M

AIM:To determine the behavior of IOP in different age groups among normal populations after water drinking test for a period of time. MATERIALS AND METHODS:This is a prospective study involving normal healthy individual taken from different age groups 20-50 years,with no relevant past medical and surgical history. Patients were instructed to drink 1Litre of water over a period of 5-10minutes after 8 hours of overnight fasting and the IOP was checked before drinking water and every 15minutes for 1 hour period followed by 2 hours after drinking water using schiotz tonometer.The difference in baseline IOP and IOP at 1 hour and 2 hour was evaluated among different age groups . RESULT: 100 patients from the age groups 20-50 years were studied .The mean baseline IOP was in the range of 12.4mmHg and the mean IOP after 1 hour was 15.3mmHg.A difference of 4-4.5 mmHg were noted in the age group of 40- 50 years .The IOP was gradually decreasing to 12.78mmHg over a period of 2 hours after WDT. CONCLUSION: The higher age group the more the rise in the IOP after WDT which concludes that as the age increases drinking litres of water over a few minutes will substantially increase the IOP,which might damage the optic nerve.

Author(s):  
Reza Razeghinejad ◽  
Zahra Tajbakhsh ◽  
Masoumeh Beigom Masoumpour ◽  
M. Hossein Nowroozzadeh

Purpose: To assess intraocular pressure (IOP) changes after the water drinking test (WDT) in patients with primary congenital glaucoma (PCG). Methods: In this prospective interventional study, 20 eyes of 20 patients with PCG were included. All patients had undergone trabeculotomy. Six out of twenty eyes had received a glaucoma drainage device (GDD) implantation. IOP was measured using an air-puff tonometer at baseline, and 15, 30, 45, and 60 min after WDT. The repeated-measures analysis of variance test was used to compare the mean IOPs at different time points. Results: The mean (± standard deviation) of participants’ age was 9.9 ± 2.7 years (range, 6 to 16 years), and 8 (40%) participants were male. The mean IOPs at baseline and 15, 30, 45, and 60 minutes after the WDT were 15.8 ± 3.7, 18.6 ± 3.4, 19.0 ± 3.8, 17.9 ± 3.8, and 16.9 ± 3.5 mmHg, respectively (P < 0.001). Pairwise comparisons revealed that the mean IOPs after 15 and 30 min were significantly greater than the baseline IOP (P < 0.001 and P = 0.002, respectively); however, the difference in mean IOPs after 45 and 60 min were not statistically significant from the baseline IOP. The averages of IOP peak and IOP fluctuation after the WDT were 20.0 ± 3.5 and 4.2 ± 2.9 mmHg, respectively. IOP fluctuation in those who underwent trabeculotomy alone was twice that of those with GDDs, but the difference was not statistically significant (5.0 vs 2.5 mmHg; P = 0.08). Conclusions: In patients with PCG, WDT induced significant IOP elevation 15 and 30 min after the test, which returned to pre-test values after 45 min.


2021 ◽  
Vol 14 (11) ◽  
pp. 1729-1734
Author(s):  
Anelisa Koh ◽  

AIM: To compare the intraocular pressure (IOP) peaks and fluctuations using water drinking tests (WDTs) and mean diurnal IOP among Filipino patients with normal eyes and glaucoma suspects METHODS: This prospective study included normal and glaucoma suspect patients. Each patient underwent both WDT and mean diurnal examination on separate visits. For mean diurnal examination, IOP was recorded every 2h for 8h while in WDT, IOP was recorded prior to WDT, and post-WDT at 5, 15, 30, 45, and 60min. IOP peak was recorded as the highest IOP for both methods, and IOP fluctuation was recorded as highest IOP minus lowest IOP. RESULTS: With the comparison of diagnostic tests, both normal eyes and glaucoma suspect groups, the peak IOP was caught at 15min. Comparative analysis of both groups also showed that the peak IOP measurements were statistically higher for the WDT compared to mean diurnal IOP (P=0.039, P=0.048 under normal group and P=0.032 and P=0.031 under glaucoma suspect group). Similarly, the WDT had a statistically higher mean IOP fluctuation score than the mean diurnal IOP method in both groups (P=0.003, P=0.011 under normal group; P=0.002 and P=0.005 under glaucoma suspect group). CONCLUSION: This study shows that WDT is a comparable diagnostic exam in predicting IOP fluctuations than mean diurnal measurement. WDT is a promising diagnostic procedure for risk assessment in glaucoma.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Eman Sayed Ahmed ◽  
Mohammed Adel Abdelshafik ◽  
Momen Mahmoud Hamdi ◽  
Noha Mohsen Mahmoud

Abstract Background Glaucoma is a chronic optic neuropathy characterized by the excavation of the optic disc due to atrophy of the retinal ganglion cells. A progression of such atrophy leads to reduction of the visual field and eventually to the loss of sight at the end-stage of the disease, Glaucoma is the second leading cause of blindness worldwide Objectives To study the correlation between intraocular pressure (IOP) fluctuation during water drinking test (WDT) and the IOP fluctuation of modified diurnal tension curve (mDTC) in glaucomatous eyes Patients and Methods Fifty participants (24 males and 26 females) were recruited in this prospective study; forty participants with known Primary Open Angle Glaucoma and the other ten participants with non- glaucomatous healthy eyes which served as control. Patients attending the outpatient clinic at Al-Demerdash Hospital and Cairo Fatemic Hospital from October 2018 to March 2019 were prospectively recruited. Four IOP measurements were taken at 8:00 am, 12:00 pm, 4:00 pm and 8:00 pm which represented the mDTC, while WDT was represented by a single measurement of IOP before ingestion of one liter of water over five minutes, followed by three IOP measurements after ingestion of this amount of water at thirty minute intervals. Results Distribution of the studied participants as regards Age and sex: 50 participants were included in the this study. 40 presented the case group (20 males and 20 females) and the mean age of the case group was 54.7 years, 10 presented the control group(4 males and 6 females) and the mean age of the control group was 51.2years. 59% of participants had a peak IOP at 8:00 am, while 10% had a peak IOP at 12:00 pm, 6% at 4:00 pm and 25% of the participants had IOP peak at 8:00 pm during the mDTC. In the WDT, 96% of the participants had a peak IOP after 30 minutes of ingesting one liter of water, while 4% had a peak IOP after 60 minutes. None of the participants had IOP peak after 90 minutes of ingesting one liter of water.. The IOP fluctuations detected during the WDT were significantly correlated to fluctuations observed during the mDTC. Conclusion The data of this study suggested that WDT can be used as a useful provocative test for the detection of the diurnal IOP peaks and fluctuation observed in the glaucoma patients.


Author(s):  
Reza Razeghinejad ◽  
M. Hossein Nowroozzadeh

Purpose: To compare the water-drinking test (WDT) and pharmacologic mydriasis as provocative tests in patients with primary angle closure suspect (PACS). Methods: This observational non-randomized comparative study evaluated changes in intraocular pressure (IOP) in 21 patients with PACS who underwent pharmacologic mydriasis and compared it with IOP changes in 26 patients given the WDT. Ocular biometric and anterior chamber parameters were also assessed. Tests were repeated on the same patient two weeks after performing laser peripheral iridotomy (LPI). Results: The mean age ± standard deviation was 60 ± 7 and 57 ± 9 years in the mydriasis and WDT groups, respectively (P = 0.201). Before LPI, both provocative tests were associated with a significant increase in IOP (mydriasis: 15.1 ± 3.1 to 16.6 ± 3.5 mmHg, P = 0.025; WDT: 16.2 ± 2.8 to 18.5 ± 3.3 mmHg, P < 0.001). However, the IOP changes were not statistically different between groups (P = 0.102). After LPI, only the WDT group showed a continued significant IOP elevation after the test (mydriasis: 16.4 ± 3.3 to 16.7 ± 3.5 mmHg, P = 0.569; WDT: 14.9 ± 3.0 to 17.8 ± 4.1 mmHg, P < 0.001). The post-test IOP change was significantly greater in the WDT than in the mydriasis group (3.0 versus 0.3 mmHg, respectively; P = 0.002). Step-wise multiple regression analysis verified the type of provocative test as the only independent factor affecting the post-test IOP change after LPI (regression coefficient: 2.664; P = 0.002). Conclusion: Pharmacologic mydriasis and the WDT had similar IOP elevation before LPI, but after LPI, IOP elevation was much greater in the WDT group.


2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Ahmed Ayuna ◽  
Ayyaz Sultan

Abstract Background Early diagnosis and treatment of ACS can reduce the risk of complications and death. Delay calling for help can increase morbidity and mortality. It is unclear which age group among patients with acute coronary syndrome tend to delay their call for help. Results Our observational retrospective study showed that men and women in their 50s and 40s respectively tend to delay their call for help from symptoms onset. For the former, the mean time delays (590 ± 71.1 min), whereas for the latter it was (1084 ± 120.1 min). Moreover, these groups tend to have a longer time delay between symptoms onset and arrival at the hospital. Among deaths, we observed that the death rate was proportional to the time delay, which is not unexpected. Next step, we plan to perform a qualitative study in the form of questionnaires to target the individuals with a high risk of CVD within these age groups. Conclusion Middle age group of both genders tend to delay their call for help when they experience symptoms of ACS; moreover, regardless of the age, the longer the delay, the higher the mortality rate. The results of this study gave us a better understanding of our local population and will pave the road for a well-structured teaching programme for them to minimise the time delay for calling for help.


2016 ◽  
Vol 46 (8) ◽  
pp. 1466-1471 ◽  
Author(s):  
Flor Diana Yokoay Claros Chacaltana ◽  
João Antonio Tadeu Pigatto ◽  
Ione Terezinha Denardin

ABSTRACT: The aim of this research was to measure the intraocular pressure (IOP) of normal chinchilla eyes using the rebound tonometer. A further aim was to assess whether there were differences in the values of intraocular pressure in relation to animals age, gender and time of day. Thirty-six chinchillas were divided into three groups of 12 chinchillas each, by age: Group I (2-6-month-old), Group II (20 and 34 months) and Group III (37 and 135 months). Ophthalmic examination was performed previously by Schirmer tear test, slit lamp biomicroscopy, indirect ophthalmoscopy and fluorescein test in all chinchillas. Three measurements of intraocular pressure were assessed on the same day (7, 12 and 19h). Tonometry was performed on both eyes using the rebound tonometer after calibration in "p" mode. Statistical analysis was performed with SigmaPlot for Windows. The mean IOP for groups I, II and III were 2.47±0.581mmHg, 2.47±0.581mmHg and 2.51±0.531mmHg, respectively. No significant differences were reported between age and IOP and no significant differences were reported between the time of day and IOP. The IOP in chinchillas did not differ significantly between genders or ages of the animals, and did not change with time of day.


Clinics ◽  
2010 ◽  
Vol 65 (10) ◽  
pp. 967-970 ◽  
Author(s):  
Rafael Lacerda Furlanetto ◽  
Antonio Carlos Facio Jr ◽  
Marcelo Hatanaka ◽  
Remo Susanna Junior

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