scholarly journals Antimicrobial and antioxidant activity of the leaves and flowers of Tabebuia aurea and Cordia glabrata

2020 ◽  
Vol 13 (5) ◽  
pp. 59
Author(s):  
E. C. Tomazeli ◽  
D. M. S. Valladão ◽  
C. R. Andrighetti ◽  
M. Magalhães ◽  
L. D. Battirola ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Antioxidant Potential ◽  
Moderate Activity ◽  
Mato Grosso ◽  
Antimicrobial And Antioxidant Activity ◽  
Antibacterial Potential

The search for new compounds of plant origin with antimicrobial activity has been the goal of many research groups, due to the increase in the number of microorganisms resistant to antimicrobials. The objective of this study was to evaluate the antimicrobial and antioxidant activity of two plant species, Tabebuia aurea (“paratudo”) and Cordia glabrata (“louro branco”), present in the state of Mato Grosso. The plant material (leaves and flowers) was extracted by maceration in 70% ethanol (Et) and polar hexane (Hex) (non-polar solvent). The determination of the antimicrobial activity was carried out by broth microdilution technique, and the antioxidant potential determined by the DPPH free radical method. In the evaluation of the antibacterial activity, the ethanolic extract of C. glabrata leaves presented better antibacterial potential for Staphylococcus aureus, revealing a minimum inhibitory concentration (MIC) of 125 μg / mL. However, for strains of Escherichia coli, Pseudomonas aeruginosa and Salmonella typhimurium, all extracts of C. glabrata showed MICs of 2000 μg / mL or higher. The ethanolic and hexanic extracts of T. aurea flowers and leaves did not show promising antibacterial potential for any of the tested strains. In the evaluation of antifungal activity against Candida albicans and Candida parapsilosis, the hexanic extract of C. glabrata leaves presented weak to moderate activity only for the C. albicans strain (MIC = 1000 μg / mL). The remaining extracts of C. glabrata and the extracts of T. aurea were not promising against the tested yeasts, showing inhibitory concentrations equal to or greater than 2000 μg / mL. In the determination of the antioxidant potential, the polar extracts (Et 70%) had a higher capacity to sequester the DPPH radical than the capacity obtained for the apolar extracts (Hex). The tests revealed promising antibacterial activity for Staphylococcus aureus and high antioxidant potential of the hydroethanolic extracts of leaves and flowers of C. glabrata, respectively.

scholarly journals FORMULATION, CHARACTERIZATION AND DETERMINATION OF ANTIBACTERIAL ACTIVITY OF POMEGRANATE (Punicagranatum) GEL.

2015 ◽  
Vol 7 ◽  
pp. 13
Author(s):  
Afendi Dahlan ◽  
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Antimicrobial Properties ◽  
Pathogenic Microorganisms ◽  
Wide Range ◽  
Common Skin

revious studies have shown that Punicagranatum (P. granatum) extract exhibited antimicrobial activity against a wide range of pathogenic microorganisms. Thus, the aim of study was to formulate and determine the effectiveness of antimicrobial properties of gel containing P. granatummethanol extract against selected common skin pathogens including Staphylococcus aureus, Staphylococcusepidermidis, Pseudomonas aeruginosaand Candidaalbicans.

scholarly journals Isolasi dan Uji Aktivitas Antimikroba Kapang Endofit dari Kayu Ulin (Eusideroxylon zwageri Teijsm & Binn.) (Isolation and Antimicrobial Activity of Endophytic Fungi from Ulin (Eusideroxylon zwageri Teijsm & Binn.))

2017 ◽  
Vol 9 (2) ◽  
pp. 65-74
Author(s):  
Nadra Khairiah ◽  
Rinne Nintasari
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Endophytic Fungi ◽  
Inhibition Zone ◽  
Antimicrobial Compound ◽  
Potato Dextrose Broth ◽  
E Coli ◽  
Antimicrobial And Antioxidant Activity ◽  
Eusideroxylon Zwageri

Endophytic fungi are reported to be potential as antibacterial, antifungal, antioxidant, anticancer, and antivirus. One of the source of endophytic fungus is ulin (Eusideroxylon zwageri Teijsm & Binn.) which produced the same antimicrobial compound with ulin wood itself. The purpose of this research was to isolate endophytic caps from ulin wood branch, and tested the antimicrobial and antioxidant activity. The isolates were fermented on PDB media (Potato Dextrose Broth), and then tested the antimicrobial activity on Eschericiacoli, Pseudomonas aeruginosa, and Enterococcus aerogenes). In this research, there were two endofit isolates (white/PT and greenish black/HT). HT endophytic isolate exhibited strong antibacterial activity against the two pathogens (P. aeruginosa and E. coli) shown in 12 mm inhibition zone, while PT endophytic isolate exhibited the E. coli in 11.5 mm inhibition zone. The highest antioxidant activity found in HT endophytic shell was 47.47%. Keywords : antimicrobial, endophytic, Eusideroxylon zwageri, fungi, ulin

scholarly journals Antioxidant activity and antimicrobial properties of Entada leptostachya and Prosopis juliflora extracts

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Mercy C. Ruto ◽  
Christine M. Ngugi ◽  
Patrick G. Kareru ◽  
Kipyegon Cheruiyot ◽  
Sylvester O. Rechab ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Antimicrobial Properties ◽  
Prosopis Juliflora ◽  
Aluminium Chloride ◽  
Total Phenolic ◽  
Moderate Activity ◽  
Bleaching Effect ◽  
Methanolic Extracts ◽  
Antimicrobial And Antioxidant Activity

Background: Natural phytoconstituents produced by plants for their sustenance have been reported to reduce disease.Objectives: This study determined the phytoconstituents, antioxidant and antimicrobial activity of crude methanolic extracts of Entada leptostachya and Prosopis juliflora extracts.Methodology: Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl and β-carotene assays; the total phenolic and flavonoid were estimated using Folin–Ciocalteau and aluminium chloride, whereas antimicrobial activity was determined using the zone of inhibition method.Results: Screening of the extracts revealed the presence of terpenoids, flavonoids, saponins and phenols. Fourier transform infrared spectra of the extracts revealed presence of hydrogen bonded –OH functional group. E. leptostachya barks had the highest antioxidant activity followed by P. juliflora roots, E. leptostachya roots and P. juliflora leaves [μg/mL]. Prosopis juliflora (roots) had the highest bleaching effect, whereas E. leptostachya (barks) had the lowest bleaching effect. The total flavonoids were determined to be 0.15 ± 0.02 mg/g, 1.18 ± 0.18 mg/g, 0.39 ± 0.05 mg/g and 0.64 ± 0.03 mg/g for E. leptostachya roots, E. leptostachya barks, P. juliflora leaves and P. juliflora roots extracts, respectively. The total phenols were determined to be 0.93 ± 0.18 mg/g, 2.69 ± 0.41 mg/g, 0.62 ± 0.08 mg/g and 0.62 ± 0.08 mg/g for E. leptostachya roots, E. leptostachya barks, P. juliflora roots and P. juliflora leaves extracts. All plant extracts exhibited moderate activity against the growth of selected microorganisms.Conclusion: Antimicrobial and antioxidant activity of the two plants was as a result of secondary metabolites found in the crude extracts.

scholarly journals SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES ON CERTAIN SUBSTITUTED ARYLAZO IMIDAZOLE CONTAINING OXADIAZOLES

2012 ◽  
Vol 20 (20) ◽  
pp. 11-24
Author(s):  
Sreedevi MEESRAGANDA ◽  
Raghavendra Gum Prasad ALURU ◽  
Spoorthy Yadan NARASIMBA ◽  
Ravindnmath Laxmana Rao Krishna RAO
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Dilution Method ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Antimicrobial Studies ◽  
Serial Dilution Method

A series of novel substituted l-[5-(2-methyl-5-nitro-4phenyl-imidazol-lyl methyl)-2-phenyl-(1,3,4)oxadiazol-3-yl]-ethanones have been synthesized. Formation of 1,3,4-oxadiazole ring was accomplished by the reaction of the corresponding hydrazide with acetic anhydride. The structure determination of these compounds has been made on the basis of IR, 1H NMR, and elemental analysis. All the compounds were screened for their antibacterial activity. The antimicrobial activity of title compounds were examined against two gram-negative (Staphylococcus aureus and Bacillus subtilis), two gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and antifungal activity was carried out against Candida albicans. The MIC values for the newly synthesized compounds have been assessed by serial dilution method All the compounds demonstrated potent antibacterial activity.

Pharmaceutical Forms with Basil and Propolis to the Benefit of the Oral Cavity. Formulation, preparation and microbiological analysis

2019 ◽  
Vol 70 (1) ◽  
pp. 343-349
Author(s):  
Olimpia Dumitriu Buzia ◽  
Nela Mardare ◽  
Ramona Dragomir ◽  
Magdalena Miulescu ◽  
Alin Laurentiu Tatu
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Oral Cavity ◽  
Ocimum Basilicum ◽  
Microbiological Analysis ◽  
Gram Negative ◽  
Pharmaceutical Form

The present paper aims at formulating, preparing, following the antibacterial activity of pharmaceutical forms with oral cavity applicability. Two pharmaceutical forms were prepared, a tincture and a toothpaste based on basil and propolis, being subsequently compared to the mix of basil and propolis tinctures that are commercially available; each pharmaceutical form was analyzed organoleptically and microbiologically. As a result of the measurements the conclusion was drawn that the tinctures prepared, the propolis tincture and the basil tincture show a strong sensitivity Staphylococcus aureus, Pseudomonas aeruginosa; and Enterococcus hormaechei.Candida albicans reacted more strongly to the propolis tincture, and less to the basil tincture. The scientific novelty of the paper consists in the formulation and determination of the antimicrobial activity of the toothpaste prepared in the laboratory of the Pharmacy Faculty of Galati. The results obtained were favorable on microorganisms acting on the oral cavity, i.e. gram positive germs, gram negative germs and fungi. Keyworlds:basil(Ocimum basilicum)propolis, lemon basil, tincture

scholarly journals Chemical composition, antimicrobial and antioxidant activity of the essential oil of leaves of Eugenia involucrata DC.

2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Adrieli Gorlin Toledo ◽  
Juliete Gomes de Lara de Souza ◽  
Jéssica Patrícia Borges da Silva ◽  
Wagner Alex Jann Favreto ◽  
Willian Ferreira da Costa ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Antioxidant Potential ◽  
Gram Positive Bacteria ◽  
Dpph Method ◽  
Germacrene D ◽  
Antimicrobial And Antioxidant Activity ◽  
Reduction Capacity

In the Myrtaceae family, the species Eugenia involucrata DC., popularly known as "cerejeira-do-mato", is traditionally used for the antidiarrheal and digestive action of its leaves. However, no studies were found in the literature regarding its antimicrobial and antioxidant potential. In this context, the objective of the present study was to determine the chemical composition by gas chromatography coupled to mass spectrometry (GC-MS) to evaluate the antimicrobial activity by the broth microdilution technique and the antioxidant activity by the 2,2-diphenyl-1-picryl-hydrazila (DPPH) method of the essential oil of E. involucrata leaves. GC-MS identified 28 compounds, all sesquiterpenes, corresponding to 89.41% of the essential oil. The antimicrobial activity of the essential oil was observed for all Gram-positive bacteria tested (Staplylococcus epidermidis, Enterococcus faecalis, Bacillus subtilis and Staplylococcus aureus) and for yeast Candida albicans. The essential oil presented a reduction capacity of DPPH up to 66.81%, evidencing its antioxidant potential. It is suggested that the antimicrobial and antioxidant action of E. involucrata essential oil is related to the presence of the major compounds, elixene (26.53%), β-caryophyllene (13.16%), α-copaene (8.41%) and germacrene D (7.17%).

Complexes of Cu (II) with a-Ketoglutaric Acid and 1- (o-tolyl) Biguanide Synthesis, characterization and biological Activity

2019 ◽  
Vol 70 (10) ◽  
pp. 3603-3610
Author(s):  
Madalina Mihalache ◽  
Cornelia Guran ◽  
Aurelia Meghea ◽  
Vasile Bercu ◽  
Ludmila Motelica ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Biological Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Copper Complexes ◽  
Substrate Adhesion ◽  
Inert Substrate

The three copper complexes having a-ketoglutaric acid (H2A) and 1- (o-tolyl) biguanide (TB) ligands have been synthesized and characterized. The proposed formulas for these complexes are: [Cu(TB)(HA)]Cl (C1), [Cu(TB)(HA)CH3COO]�H2O (C2) and [Cu(TB)(HA)](NO3) (C3) where HA represents deprotonated H2A. The complexes obtained were tested for antibacterial activity against Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853, antifungal activity on Candida albicans ATCC 10231 and antitumor activity on HeLa tumor cells. Due to the antitumor, antifungal, antimicrobial activity and inhibition of inert substrate adhesion, complexes synthesized could be used for potential therapeutic applications.

Evaluation of antioxidant and antimicrobial activity of Ziziphora ‎clinopodiodes essential oil eluted at different times

2020 ◽  
Vol 16 ◽  
Author(s):  
Mojgan Alizadeh ◽  
Akram Arianfar ◽  
Ameneh Mohammadi
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Positive Control ◽  
Essential Oil Composition ◽  
Oil Composition ◽  
Citronellic Acid ◽  
Antimicrobial And Antioxidant Activity

Objective: Ziziphora clinopodioides is an edible medicinal plant belongs to the Labiatae family that widespread all over Iran. It used as culinary and also in cold and cough treatments in Iran. The aim of present work was to evaluate the effect of different timeframes during the hydrodistillation on essential oil composition, antimicrobial and antioxidant activity. Materials and Methods: The essential oil of Z. clinopodiodes was extracted via hydrodistillation with Clevenger apparatus. The fractions of essential oil were captured at 6 times from the beginning of the distillation: (10, 20, 60, 120, 180 and 240 min). The fractions of essential oil were analyzed by GC/MS and their antibacterial, antifungal and antioxidant activities were studied by Disk - well diffusion and DPPH methods respectively. Results: Six distillation times and whole essential oil were captured during the hydrodistillation. Essential oil yield dropped off significantly during distillation progressed (1.0% for 10 min and 0.025 for 240 min). 1,8 Cineol, Isomenthone, Pulegone, Piperitenone and Citronellic acid were major compounds in fractions and they were affected by distillation times. Pulegone was major compound in all of essential oils. In antioxidant activity assay, whole essential oil was stronger than was stronger than positive control and fractions of essential oil, because of higher levels of Isomenthone, Piperitenone and Citronellic acid. Strongest antimicrobial activity against S. aureus, E. coli and C. albicans was observed from 10 min fraction. Conclusion: Our results indicated that distillation time can create essential oils with specific properties and we can achieve to more efficient essential oil in short times.

scholarly journals ANTIMICROBIAL AND ANTIOXIDANT EFFECT OF NATURAL EXTRACTS FROM LEAVES, ROOT, STEM AND FLOWERS OF BACCHARIS LATIFOLIA FROM ECUADOR

2020 ◽  
pp. 78-84
Author(s):  
FAVIAN BAYAS-MOREJON ◽  
ANGELICA TIGRE ◽  
RIVELINO RAMON ◽  
DANILO YANEZ
Keyword(s):  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Potassium Phosphate ◽  
Natural Antioxidants ◽  
Butylated Hydroxytoluene ◽  
Penicillin G ◽  
Diffusion Method ◽  
E Coli ◽  
Antibacterial And Antioxidant Activity

Objective: The increase in chronic and degenerative diseases and the use of synthetic antioxidants such as (butylated hydroxyanisole (BHA) or butylated hydroxytoluene (BHT)) are being restricted because they can be considered carcinogenic. Therefore, there is a growing interest in the search for natural antioxidants, especially from plants, due to their content in different bioactive compounds, such as antioxidants and antimicrobials. To evaluate the antibacterial and antioxidant activity of Baccharislatifolia extracts. Methods: For the determination of the antimicrobial activity of extracts of leaves, root, stem and flowers of Baccharislatifolia (Bl), the disk plate diffusion method was used, the strains of Listeria, Salmonella and E. coli were studied; antibiotics Penicillin G and Ciprofloxacin were the controls. For the antioxidant activity, a solution of H2O2 (Abs at 230 nm) was prepared in Potassium Phosphate Monobasic-Sodium Hydroxide buffer. Results: The antimicrobial activity against Listeria and Salmonella, showed that the extracts of leaves and flowers were more effective with inhibition zones>15 mm and>20 mm respectively. In front of E. coli, the extracts of flowers and stem were the best with zones>7.0 mm. Antibiotics studied inhibited the development of Listeria and Salmonella. However, E. coli isolates were resistant. In the antioxidant activity, the flower extract of Bl in 60 mg/ml presents a higher effect with 47.25%. Conclusion: Bl extracts from leaves and flowers were more efficient both in their antimicrobial and antioxidant capacity.

Antimicrobial Activity of Isopteropodine

2005 ◽  
Vol 60 (5-6) ◽  
pp. 385-388 ◽  
Author(s):  
Rubén García ◽  
Cesia Cayunao ◽  
Ronny Bocic ◽  
Nadine Backhouse ◽  
Carla Delporte ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Gram Positive ◽  
Uncaria Tomentosa ◽  
Gram Positive Bacteria

Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial activity against Gram positive bacteria.

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