EFFECT OF TRIMETAZIDINE ON HEART PARAMETERS IN PATIENTS AFTER VIRAL PNEUMONIA WITH A TEST WITH A FIXED RESPIRATORY RATE

2021 ◽  
pp. 39-43
Author(s):  
Ирина Владимировна Кочеткова ◽  
Елена Анатольевна Фурсова
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Respiratory Rate ◽  
Clinical Laboratory ◽  
Functional Class ◽  
Practical Significance ◽  
Software Systems ◽  
Antianginal Agent ◽  
Exertional Angina ◽  
Rate Test

Статья посвящена оценке динамики традиционных показателей вариабельности ритма сердца (ВРС) на фоне терапии триметазидином у больных с кардиальной патологией после перенесенной коронавирусной пневмонии при использовании методики темпа дыхания. Выполнен анализ анамнестических, клинико-лабораторных и микробиологических показателей 50 лиц мужского пола с диагнозом стабильной стенокардией напряжения II функционального класса, после перенесенной коронавирусной пневмонии с использованием аппаратно-программных комплексов. При использовании пробы с ФТД у пациентов с ИБС после перенесенной коронавирусной пневмонии на фоне терапии триметазидином было выявлено два типа реакции: первый - позитивный достоверный прирост параметров вариабельности ритма сердца, второй - U-образный вид изменения показателей ВРС: снижение при проведении методики в 6 секунд и дальнейший рост при 12 секундах. Клиническая значимость методики ФТД достаточно велика, она позволяет доктору по динамике показателей ВРС: СВВР - показатель средней взвешенной вариации ритмограммы, SDNN - показатель суммарного эффекта вегетативной регуляции кровообращения, рассуждать об адекватности восстановительного периода у постковидных пациентов с ИБС и проводить коррекцию тактики лечения. Триметазидин является эффективным антиангинальным средством в комплексной терапии пациентов со стабильной стенокардией после перенесенной коронавирусной пневмонии. На фоне лечения выявлено уменьшение числа эпизодов, а также времени ишемической депрессии, что несомненного благоприятно для пациента. При исходно низком показателе СВВР добавление триметазидина в комплексную терапию ИБС может свидетельствовать о восстановлении дисбаланса вегетативной нервной системы Purpose: to evaluate the change in heart rate variability (HRV) indicators during treatment with trimetazidine in patients with coronavirus pneumonia after coronavirus pneumonia using a fixed respiratory rate test (FTD). Material and methods. A comparative analysis of anamnestic, clinical, laboratory and microbiological indicators of 50 men with stable exertional angina of II functional class (NYHA FC) after suffering coronavirus pneumonia using hardware and software systems was carried out. Results. When using a test with PTD in patients with coronavirus pneumonia after suffering from coronavirus pneumonia during therapy with trimetazidine, two types of reaction were revealed: the first was a positive significant increase in heart rate variability parameters, the second was a U-shaped type of change in HRV parameters: a decrease in 6-second breathing and further growth with 12-second breathing. Conclusion. The practical significance of the test with FTD is quite large, it allows the doctor, by the type of change in HRV parameters: SDNN - the total effect of autonomic regulation of blood circulation, SVVR - the average weighted variation of the rhythmogram, to talk about the adequacy of the rehabilitation process of postcovid patients with IHD and to correct the treatment tactics. Trimetazidine is an effective antianginal agent in the complex treatment of patients with stable angina pectoris after suffering from coronavirus pneumonia. Against the background of therapy, there is a decrease in the number of episodes, the time of ischemic depression, which is a favorable factor. With an initially low value of SVVR, the addition of trimetazidine to the complex therapy of ischemic heart disease may indicate the restoration of a disturbed vegetative balance

scholarly journals Changes in Respiratory Rate, Blood Pressure and Heart Rate Variability in Rabbits during Orthostasis

2006 ◽  
Vol 75 (1) ◽  
pp. 3-12 ◽  
Author(s):  
J. Mokrý ◽  
T. Remeňová ◽  
K. Javorka
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Respiratory Rate ◽  
Supine Position ◽  
Spectral Power ◽  
Systemic Blood Pressure ◽  
Microcomputer System ◽  
Systemic Blood ◽  
Frequency Bands

The purpose of the study was to evaluate the changes of respiratory rate, systemic blood pressure and heart rate variability parameters (HRV) during orthostasis in anaesthetized rabbits. Furthermore, these changes were influenced by affecting the renin-angiotensin-aldosterone (RAA) system and autonomic nervous system (ANS) to study the mechanisms participating in activity of spectral frequency bands of HRV in rabbits. Ten adult rabbits (Chinchilla) were anaesthetized by ketamine and flunitrazepam. The systemic blood pressure, tidal volume and respiratory rate were measured. HRV was evaluated by microcomputer system VariaPulse TF3E. The R-R intervals were derived from the electrocardiogram signal from subcutaneous needle electrodes. The evaluation of HRV in very low (VLF; 0.01-0.05 Hz), low (LF; 0.05-0.15 Hz) and high frequency bands (HF; 0.15-2.0 Hz) was made and parameters of frequency and time analysis were calculated. The measurements were made in horizontal (supine) position, in orthostasis (the angle of 60 °) and again in supine position before and after enalapril (0.5 mg/kg b.w.), metipranolol (0.2 mg/kg b.w.), and after subsequent bilateral cervical vagotomy. The orthostasis in anaesthetized rabbits is accompanied by depression of respiratory rate reversed only by vagotomy. Furthermore, decrease of systemic blood pressure, unchanged heart rate and increased characteristics of heart rate variability were found, with predominant increase of spectral power in LF and VLF bands. This elevation can be eliminated only by complete blockade of ANS. Although the participation of ANS or RAA system in modification of individual HRV frequency bands is not as specific as in humans, we confirmed the participation of RAA system in determination of the VLF band.

scholarly journals The Effect of Live Spontaneous Harp Music on Patients in the Intensive Care Unit

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ann Marie Chiasson ◽  
Ann Linda Baldwin ◽  
Carrol Mclaughlin ◽  
Paula Cook ◽  
Gulshan Sethi
Keyword(s):  
Blood Pressure ◽  
Intensive Care Unit ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Intensive Care ◽  
Oxygen Saturation ◽  
Respiratory Rate ◽  
Rest Period ◽  
Underlying Mechanism ◽  
To Receive

This study was performed to investigate the effect of live, spontaneous harp music on individual patients in an intensive care unit (ICU), either pre- or postoperatively. The purpose was to determine whether this intervention would serve as a relaxation or healing modality, as evidenced by the effect on patient’s pain, heart rate, respiratory rate, blood pressure, oxygen saturation, and heart rate variability. Each consenting patient was randomly assigned to receive either a live 10-minute concert of spontaneous music played by an expert harpist or a 10-minute rest period. Spontaneous harp music significantly decreased patient perception of pain by 27% but did not significantly affect heart rate, respiratory rate, oxygen saturation, blood pressure, or heart rate variability. Trends emerged, although being not statistically significant, that systolic blood pressure increased while heart rate variability decreased. These findings may invoke patient engagement, as opposed to relaxation, as the underlying mechanism of the decrease in the patients’ pain and of the healing benefit that arises from the relationship between healer, healing modality, and patient.

scholarly journals Heart Rate and Respiratory Rate Influence on Heart Rate Variability Repeatability: Effects of the Correction for the Prevailing Heart Rate

2016 ◽  
Vol 7 ◽  
Author(s):  
Jakub S. Gąsior ◽  
Jerzy Sacha ◽  
Piotr J. Jeleń ◽  
Jakub Zieliński ◽  
Jacek Przybylski
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Respiratory Rate

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

2011 ◽  
Vol 121 (5) ◽  
pp. 215-222 ◽  
Author(s):  
Matthijs Kox ◽  
Jan C. Pompe ◽  
Johannes G. van der Hoeven ◽  
Cornelia W. Hoedemaekers ◽  
Peter Pickkers
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Respiratory Rate ◽  
Spontaneous Breathing ◽  
Breathing Patterns ◽  
Paced Breathing ◽  
Cardiac Autonomic Nervous System ◽  
Wide Range ◽  
Static Conditions ◽  
The Impact

HRV (heart rate variability) analysis is a widely employed method to assess cardiac autonomic nervous system activity. Accurate HRV measurement is critical to its value as a diagnostic and prognostic tool. Different breathing patterns may affect HRV, but results obtained under static conditions are conflicting. HRV indices decrease considerably during systemic inflammation evoked by experimental endotoxaemia, enabling the determination of the effects of different breathing patterns on HRV in a dynamic setting. We investigated the impact of different breathing patterns on short-term HRV measurements during experimental endotoxaemia. Furthermore, we assessed whether paced breathing improved HRV reproducibility. Twelve healthy male volunteers received an intravenous bolus (2 ng/kg of body weight) of endotoxin [LPS (lipopolysaccharide), derived from Escherichia coli O:113] on two occasions with an interval of 2 weeks. Five-minute HRV recordings were performed just prior to LPS administration and hourly thereafter until 8 h post-LPS. Three breathing protocols were employed every hour: (i) spontaneous breathing, (ii) metronome-guided breathing at the subject's normal respiratory rate (‘paced’) and (iii) metronome-guided breathing at 150% of the subject's normal respiratory rate (‘mild hyperventilation’). LPS administration resulted in a sharp decrease in all of the HRV indices measured, which was similar during both LPS administrations. Neither paced breathing nor mild hyperventilation influenced HRV indices compared with spontaneous breathing. Paced breathing did not improve reproducibility as it did not exert a significant effect on intra-subject coefficients of variation and intra-class correlation coefficients (calculated between both visits). In conclusion, over a wide range of HRV magnitudes during experimental endotoxaemia, neither paced breathing nor mild hyperventilation affected HRV indices. Moreover, paced breathing did not result in a significant improvement in reproducibility. Therefore employing a paced breathing protocol is not required to obtain valid HRV data during endotoxaemia.

scholarly journals Psychophysiology of slow breathing exercises using heart rate variability measurements for stress reduction

2016 ◽  
Vol 3 (2) ◽  
Author(s):  
Dante Jr. Guanlao Simbulan
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Respiratory Rate ◽  
Stress Reduction ◽  
Tai Chi ◽  
Chronically Ill ◽  
Positive Sign ◽  
Breathing Exercises ◽  
Skin Response ◽  
Slow Breathing

Slow breathing exercises, associated with meditation and other eastern style modalities like tai chi and hatha yoga, are now increasingly employed in mainstream medicine to reduce stress, attenuate moderate hypertension, and alleviate symptoms of lifestyle-related illnesses. The clinical literature on slow breathing exercises includes studies employing various physiological measurements, including heart rate variability (HRV), galvanic skin response, and changes in skin temperature. HRV has been increasingly used to measure the activity of the autonomic nervous system in various human studies employing healthy and chronically ill subjects. 1. Objective: To understand the effects of slow breathing exercises on heart rate variability as a complementary intervention for stress reduction. 2. Method: Four subjects, through repetitive trials, were instructed to slow down their breathing following a metronome at 10 breaths per minute or 6 breaths per minute or spontaneously relax to slow down their respiratory rate. The ECG, heart rate, and respiratory rate were recorded using a Powerlab set-up (ADI). 3. Key Results:  Results showed an increase in amplitude of heart rate variability during these slow breathing exercises, either through the metronome-guided or spontaneous slow-breathing exercises, especially around a breathing frequency of 6 breaths per minute. The increased amplitude of heart rate variability can be seen as a positive sign, a marker for sympathovagal balance. 4. Conclusion: HRV measurements have shown that slow breathing exercises can increase heart rate variability.  Future protocols for clinical trials are being projected using the HRV technique and other physiological measurements for studying effects of yoga-based complementary interventions for stress reduction.

scholarly journals Effects of Mentha Piperita Essential Oil Uptake or Inhalation on Heart Rate Variability and Cardiopulmonary Regulation during Exercise

2021 ◽  
Vol 10 (2) ◽  
pp. 65-72
Author(s):  
Tso-Yen Mao ◽  
◽  
Chun-Feng Huang ◽  
De-Yen Liu ◽  
Chien-Ting Chen ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Oil ◽  
Respiratory Rate ◽  
Low Frequency ◽  
Carbon Dioxide Production ◽  
Mentha Piperita ◽  
Control Group ◽  
Frequency Area

This study compares the effects of the uptake or inhalation of 50uL Mentha piperita (MP) essential oil for 10 days on heart rate variability (HRV) and cardiopulmonary regulation during various exercise intensities. Forty-eight healthy male subjects were randomly assigned to MP uptake (MPU; n=16), MP inhalation (MPI; n=16), and control group (C; n=16). All participants were measured resting HRV, respiratory, cardiovascular, and metabolic parameters during aerobic, anaero- bic, and graded exercise tests (GXT) before and after treatment. There were significant increases in the low-frequency area (LFa; 1.8±0.1 vs 2.2±0.2 ms²), the ratio of low frequency to respiration frequency area (LFa/RFa; 0.9±0.1 vs 1.3±0.1) at resting and carbon dioxide production (VCO 2 ; 41.2±4.0 vs 49.2±6.8 mL/min -1 /kg -1 ), ventilation per minute (V E ; 80.2±4.3 vs 97.5±5.5 L/min -1 ), and respiratory rate (RR; 38.2±1.9 to 44.3±2.1 breath/min -1 ) in an anaerobic test following MPU inter- vention. In GXT, maximal carbon dioxide production (VCO 2max; 51.9±3.5 to 59.1±6.4 mL/min -1 /kg -1 ), maximal ventilation per minute (V Emax ; 126.4±6.5 to 138.4±5.4 L/min -1 ) and maximal respiratory rate (RR max ; 52.7±3.6 to 60.1±2.3 breath/min -1 ) significantly increased in MPU. The correlations of ΔLFa with ΔVCO 2max , ΔV Emax , and ΔRR max in the MPU group were signifi- cant. Continuous uptake or inhalation of 50uL MP oil for 10 days does not improve aerobic capacity and maximal exercise performance, but 10 days’ uptake of MP essential oil increased sympathetic activity at rest and may relate to respiratory regulation under high-intensity exercise.

scholarly journals Heart rate variability and emotional state dynamics in zumba class

2021 ◽  
Vol 7 (3B) ◽  
pp. 239-249
Author(s):  
Valeriia A. Demareva ◽  
Tatiana V. Mayasova ◽  
Svetlana A. Zaitseva ◽  
Elena G. Gutsu ◽  
Nadezhda N. Demeneva ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Research Methods ◽  
Emotional State ◽  
Research Question ◽  
Practical Significance ◽  
Empirical Research Methods ◽  
Fitness Training ◽  
Diagnostic Technologies ◽  
Control Functional

The relevance of the research question arises from the need to assess the safety and benefits of Zumba®Fitness classes as well as from the lack of diagnostic and methodological tools to plan the training and predict fitness outcomes. The aim of this article was to examine heart rate variability (HRV) and emotional disadaptation (ED) during Zumba®Fitness classes. Wireless cardiointervalography as well as the LED (level of emotional disadaptation) test were used as empirical research methods. The paper showed the effect of Zumba®Fitness on HRV, as well as on LED. Practical significance: The current study proves the necessity to control functional stateduring fitness training, which is an important factor in planning the training process and predicting its results. At the same time, good results of fitness training require the use of modern diagnostic technologies based on objective research methods.

The effect of carbon dioxide, respiratory rate and tidal volume on human heart rate variability

2003 ◽  
Vol 48 (1) ◽  
pp. 93-101 ◽  
Author(s):  
M. Pöyhönen ◽  
S. Syväoja ◽  
J. Hartikainen ◽  
E. Ruokonen ◽  
J. Takala
Keyword(s):  
Carbon Dioxide ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Tidal Volume ◽  
Respiratory Rate ◽  
Human Heart
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