scholarly journals Pengaruh Pemberian Alpukat Terhadap Kadar Kolesterol Total Darah Pada Mahasiswa/i Obesitas Di Fakultas Kedokteran Universitas HKBP Nommensen Medan Tahun 2019

2021 ◽  
Vol 6 (2) ◽  
pp. 40-43
Author(s):  
Syupiarni Putri Waruwu ◽  
Joseph Partogi Sibarani ◽  
Saharnauli Janna Verawaty Simorangkir

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Putri Mira Magistri ◽  
Rismawati YaswiR ◽  
Yustini Alioes

AbstrakMasyarakat menggunakan berbagai cara pengolahan sebelum mengonsumsi telur yang dapat berpengaruh terhadap kadar zat gizi yang terkandung didalamnya, termasuk kadar kolesterol dalam telur yang juga akan mempengaruhi kadar kolesterol dalam darah. Tujuan penelitian ini adalah menentukan pengaruh pemberian berbagai olahan telur terhadap kadar kolesterol total darah mencit. Penelitian menggunakan 24 ekor mencit (Mus musculus) jantan albino umur 3 – 4 bulan dengan berat badan sekitar 30 – 40 gram. Jenis kandang yang digunakan adalah kandang kotak (box) sebanyak 24 unit dengan ukuran 28x30x20 cm. Metode yang digunakan ialah eksperimen dengan Rancangan Acak Lengkap (RAL) terdiri dari 6 unit perlakuan, yaitu unit perlakuan K (Kontrol), unit perlakuan A (telur mentah), unit perlakuan B (telur goreng), unit perlakuan C (telur rebus), unit perlakuan D (telur setengah matang) dan unit perlakuan E (telur asin). Dosis perlakuan adalah 1,56ml/20gram berat badan/mencit dan masing-masing perlakuan diulang 4 kali. Parameter yang diukur adalah kadar kolesterol total darah mencit. Hasil analisis keragaman menunjukan bahwa pemberian berbagai olahan telur memberikan pengaruh berbeda sangat nyata (P<0.01) terhadap kadar kolesterol total darah mencit. Berdasarkan hasil penelitian dapat disimpulkan bahwa rerata kadar kolesterol total darah mencit setelah diberikan berbagai olahan telur adalah telur mentah 106.96 mg/dl, telur goreng 143.53 mg/dl, telur rebus 194.50 mg/dl, telur setengah matang 180.91 mg/dl, dan telur asin 158.27 mg/dl.Kata kunci: olahan telur, kadar kolesterol total darah, mencit AbstractPeople use various methods of processing before consumption eggs which can affect the levels of nutrients contained in, including cholesterol content which can also affect the levels of total cholesterol in blood. The objective of this study was to determine the effect of giving a variety of processed egg on total cholesterol levels of mice. The experiment used 24 male albino mice (Mus nusculus) age 3 – 4 months old with 30 – 40 grams of body weight. The den used was 24 units of box with size of 28x30x20 cm. The experiment used Completely Randomized Design (CRD) consist of 6 treatment units which was K (control), A (raw egg), B (fried egg), C (boiled egg), D (soft-boiled egg), and E (salted egg). The dosage was  1.56 ml/20 grams of body weight/mice and 4 replication for each treatment units. The parameter measured was total blood cholesterol level of mice.  Results of analysis of variance showed that giving of a variety of processed egg gave highly  significant  effect (P <0.01) on total blood cholesterol levels of mice. Based on the results of this study, it can be concluded that the average total blood cholesterol levels of mice after giving of various preparations of eggs is as follows: raw eggs 106.96 mg / dl, fried eggs 143.53 mg / dl, boiled eggs 194.50 mg / dl, soft-boiled eggs 180.91 mg / dl, and salted egg 158.27 mg / dl..Keywords: processed egg, total blood cholesterol level,  mice


2014 ◽  
Vol 10 (2) ◽  
Author(s):  
Egi Supriyadi ◽  
Roslizawaty Roslizawaty ◽  
Zuhrawati Zuhrawati

This study aimed to determine the effect of bandotan (Ageratum conyzoides L) leaf extract on total blood cholesterol level of broiler. This study used 15 broiler aged of 25 days. This study was an experimental study using completely randomized design (CRD) unidirectional pattern with 3 treatment groups and 5replications each. Group 0 (P0) was not given bandotan leaf extract, group 1 (P1) was given 3 ml bandotan leaf extract, and group 2 (P 2) was given 5 ml bandotan leaf extract. The administration of Bandotan leaf extract was carried out once a day for 5 consecutive days. On day 6 after treatment, the blood was collected then examined for total blood cholesterol level by precipitation method. Data was analyzed using analysis of variance. The result showed that the average of total cholesterol level on group P0, P1, and P2 was 134.20+10.50, 125.15+8.20, and 113.34+7.50 mg/dl, respectively. In conclusion, bandotan leaf extract decrease blood cholesterol levels of broiler.Key words: broiler, bandotan leaf extract, total cholesterol level


2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Zuhrawati N. A.

This study aims to know the effect of pineapple juice on blood cholesterol level of male hypercholesterolemic rabbits. A total of 12 local male rabbits aged 1-2 years with body weight ranging from 0.9-1.6 kg were used as sampel. Sample were divided randomly into 4 treatmentgroups, each group consisting of 3 replications. All rabbits were initially examined for the total cholesterol levels, before fed with a diet to makehypercholesterolemic. The rabbits were then fed with a mixture of 90% sugar solution as much as 6 gr/kg body weight and egg yolks as much as3 gr/kg body weight for 7 consecutive days using a stomach sonde, followed with re-examination of total cholesterol. Samples were thenadministered with pineapple juice on KI (10 g /kg BW), KII (20 g/kg BW), and KIII (30 g/kg), while the K0 as controls were not given pineapplejuice. After 10 days of administration of pineapple juice, rabbit blood was collected through the auricular vein for total cholesterol examinationusing the Chod-PAP. Data were analyzed by ANOVA completely randomized design (CRD) one way, and the difference between the treatmentgroup was examined using Duncan's multiple test. Results showed that the mean (±SD) of total blood cholesterol levels of rabbits (mg/dl) groupsK0, KI, KII, and KIII after the administration of pineapple juice in a row was 176.60 ± 57.10; 66.60±12.50; 63±17.70; and 57.60±24.80.Statistical analysis showed that treatment affect significantly (P0.05) to decrease total blood cholesterol levels of rabbits. In conclusion, theadministration of pineapple juice (Ananas comosus) for ten consecutive days can decrease blood total cholesterol of hypercholesterolemiarabbits.____________________________________________________________________________________________________________________Key words: diet cholesterol, pineapple juice, total cholesterol levels, rabbit


2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Magdalena Talumewo ◽  
Murniati Tiho ◽  
Michaela E. Paruntu

Abstract: Unhealthy eating habit could lead to obesity. Obesity is always associated with the increase of blood cholesterol level (hypercholesterolemia). Increased cholesterol level is a risk factor of the death in young adult. This study was aimed to obtain the profile of total blood cholesterol levels among students of Faculty of Medicine Sam Ratulang University with body mass index (BMI) ≥23 kg/m2. This was a descriptive study. Samples were obtained by using total sampling method. There were 53 students involved in this study consisted of 22 males and 31 females. The results showed that 23 students (43.4%) had normal total cholesterol levels and 30 students (56.6 %) had low total cholesterol levels. Conclusion: More than half of the students of Faculty of Medicine Sam Ratulangi University with BMI ≥23 kg/m2 had low total cholesterol level.Keywords: total cholesterol, BMI ≥23 kg/m2. Abstrak: Kebiasaan makan yang tidak sesuai dengan kaidah sehat dapat mengakibatkan obesitas. Kondisi obesitas selalu dikaitkan dengan peningkatan kadar kolesterol dalam darah atau hiperkolesterolemia. Peningkatan kadar kolesterol merupakan factor risiko penyebab kematian di usia dewasa muda. Penelitian ini bertujuan untuk mengetahui gambaran kadar kolesterol total darah pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi dengan indeks massa tubuh (IMT) ≥23 kg/m2. Jenis penelitian ialah deskriptif. Sampel diperoleh dengan metode total sampling. Penelitian ini diikuti oleh 53 orang subyek penelitian yang terdiri dari 22 orang laki-laki dan 31 orang perempuan. Hasil penelitian mendapatkan 23 orang (43,4%) memiliki kadar kolesterol total normal dan 30 orang (56,6%) memiliki kadar kolesterol total rendah. Simpulan: Lebih dari setengah mahasiwa Fakultas Kedokteran Universitas Sam Ratulangi dengan IMT ≥23 kg/m2 memiliki kadar kolesterol total rendah.Kata kunci: kolesterol total, IMT ≥23 kg/m2


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Regina Wahjoeni ◽  
Yanti M. Mewo ◽  
Michaela E. Paruntu

Abstract: High level of total cholesterol in blood or known as hypercholesterolemia causes atherosclerosis or constriction of the blood vessels. Aterosclerosis is considering as an important factor in coronary heart disease event. Consuming food with high cholesterol plays an important role on elevating total blood cholesterol. Vegetarian has better health quality than meat-eaters. This group has lower total blood cholesterol, triglicerid and LDL compared to meat eaters. The pourpose of this study was to find out the description about total blood cholesterol level in vegetarian lacto-ovo students. This descriptive study was followed by 25 respondents total that consist of 14 male respondents (56%) and 11 female respondents (44%). The result of this study shown that 23 respondents (92%) have normal total blood cholesterol level and 2 respondets (8%) have borderline high blood total cholesterol level. According to the results, it can be concluded that the description of total cholesterol blood level in vegetarian lacto-ovo students mostly are in normal level.Keywords: total cholesterol, vegetarian lacto-ovo studentsAbstrak: Kadar kolesterol yang tinggi dalam darah atau hiperkolesterolemia menyebabkan aterosklerosis atau penyempitan pembuluh darah. Aterosklerosis adalah faktor penting pendukung terjadinya penyakit jantung koroner. Mengonsumsi makanan dengan kandungan kolesterol tinggi berperan dalam terjadinya peningkatan kolesterol darah. Vegetarian memiliki mutu kesehatan yang baik. Kelompok ini memiliki kadar kolesterol total, trigliserol, dan LDL yang lebih rendah dibandingkan pemakan daging. Tujuan penelitian ini adalah untuk mengetahui gambaran kolesterol total darah pada mahasiswa vegetarian lacto-ovo. Penelitian ini bersifat deskriptif. Pengambilan sampel diambil dengan menggunakan metode total sampling. Penelitian ini diikuti oleh 25 orang responden yang terdiri dari 14 responden laki-laki (56%) dan 11 responden perempuan (44%). Hasil penelitian ditemukan 23 orang (92%) dengan kadar kolesterol total normal dan 2 orang (8%) dengan kadar kolesterol total pada ambang batas tinggi. Dari hasil penelitian ini dapat disimpulkan bahwa gambaran kadar kolesterol total darah pada mahasiswa vegetarian sebagaian besar memiliki kadar kolesterol total normal.Kata kunci: kolesterol total, mahasiswa vegetarian lacto-ovo


2016 ◽  
Vol 15 (9) ◽  
pp. 873-877
Author(s):  
Saeid Reza Doustjalal ◽  
Hlaing Thaw Dar ◽  
Khin Thant Zin ◽  
Kumar Raghav Gujjar ◽  
Ratika Sharma ◽  
...  

2010 ◽  
Vol 9 (3) ◽  
pp. 312-318 ◽  
Author(s):  
I. Nyoman Pugeg Arya ◽  
Suswini Kusmaninga ◽  
Afifah Bambang Sutjiatmo ◽  
Yuli Sumartini ◽  
Aida Nursidah ◽  
...  

2019 ◽  
Vol 7 (2) ◽  
pp. 120-124
Author(s):  
Adelina Ayu Nugraheni ◽  
Mohammad Jaelani ◽  
Arintina Rahayuni ◽  
Pujo Semedi

Background : Women are two times have hypercholesterolemia 14.5% after menopause due to blood cholesterol levels increase because of the hormone estrogen is not formed. Drugs can be used to reduce cholesterol levels, but using drugs to reduce cholesterol levels have side effects. An alternative way that can be used in preventing a long-term increase in blood cholesterol levels and to reduce the dosage of drugs use is by using natural ingredients such as red guava fruit and tomatoes.Objective : This research aim to know the effectiveness of tomato juice and red guava juice on total cholesterol in overweight women.Method : This research was a clinical nutrition research. Type of research was true experiment research and study design was randomized pre-and post-test control group design. The tomato and red guava juice consist of  300 grams of tomatoes and red guavas, was given for 21 days to 22 respondents (11 treatments and 11 controls).In the treatment group there was lowering in total blood cholesterol and the control group with an increase in blood cholesterol levels.Result : Total Blood Cholesterol influenced by the lycopene intake and a decrease in total blood cholesterol levels in the treatment and control groups (p 0.05).Conclusion : 250 ml of tomato juice and red guava juice was given everyday within 3 weeks could reduce total cholesterol 3,01 mg/dl clinically, but not significant statistically.


Jurnal Kimia ◽  
2016 ◽  
Author(s):  
Sri Wahjuni ◽  
Ni Luh Rustini ◽  
Putu Yuliantari

Excessive fat consumption can increase blood cholesterol level. Phytosterol composition in the plant can decrease blood cholesterol level. One of the plants that contain phytosterol is beans. This study was to prove the effect of antihypercholesterol the ethanol extract of the beans (Phaseolus vulgaris L.) with variety of doses of 50 mg/Kg BW; 100 mg/Kg BW and 150 mg/Kg BW in male Wistar rats with high fat level condition. Subjects of this study were 24 Wistar rats divided into 6 groups randomly with posttest control group study design. First group as negative control, second group as positive control, and the third (high cholesterol diet and ethanol extract in dose of 50 mg/kg,bw), fourth ( high cholesterol diet and ethanol extractin dose of 100 mg/kg,bw), fifth ( high cholesterol diet and ethanol extract in dose of 150 mg/kg,bw),  sixth (high cholesterol diet and simvastatin drug). The data was analyzed with ANOVA Tukey test. The result of this study shows total cholesterol levels decrease 23,88%; 30,14%; 35,82%. Cholesterol LDL levels decrease 38,09%; 52,38%; 61,35%. Cholesterol HDL levels increase 21,86%; 56,56%; 63,84%. Dose variant on this study giving the best result to decrease total cholesterol levels and LDL was 150 mg/Kg BW. Furthermore, 100 mg/Kg BW dose gave the best result to increase HDL cholesterol level. Based on the results it can be suggested that beans ethanol extract is able to decrease total cholesterol level, LDL and increase HDL cholesterol levels.  


Author(s):  
Dedi Rahmat Dudi Sayu Putu Yuni Paryati

Abstrak Penelitian dilakukan untuk mengetahui pengaruh keragaman gen DGAT1 pada domba Padjadjaran terhadap kandungan kolesterol dan trigiserida darah. Ternak domba yang digunakan dalam penelitian ini merupakan domba Padjadjaran umur 1,5 tahun, yang telah diidentifikasi memiliki genotipe tertentu berdasarkan gen DGAT1. Total sampel domba yang digunakan sebanyak 15 ekor. Sampel yang digunakan terdistribusi dalam tiga genotipe (5 CC, 5 CT dan 5 TT). Penilaian komponen lemak meliputi: (1) Kandungan kolesterol total dan Kandungan Trigeliserida. Pemeriksaan kolesterol menggunakan metode: CHOD-PAP (Cholesterol Oxidase-Peroxidase Aminoantipyrine Phenol). Hasil penelitian menunjukkan bahwa kadar kolesterol total darah domba Padjajaran berada pada kisaran normal dan keragaman gen DGAT1 tidak berpengaruh nyata terhadap kadar kolesterol darah. Dari ketiga genotype DGAT, menunjukkan kelompok CC memiliki kadar kolesterol total paling rendah, dibandingkan kelompok lainnya, sedangkan kadar trigliserida terendah didapatkan pada genotype TT, namun tidak berbeda nyata dibandingkan dengan genotype CC dan CT. Kata-kata kunci: domba Padjadjaran, gen DGAT1, kolesterol Abstract The study was conducted to determine the effect of DGAT1 gene diversity on Padjadjaran sheep to cholesterol and triglyceride levels. The sheep used in this study is a 1.5-year-old Padjadjaran sheep, which has a specific genotype based on the DGAT1 gene. Total sample of sheep that used as many as 15 tail. The samples used were distributed in three genotypes (5 CC, 5 CT and 5 TT). Assessment of fat content are total cholesterol and Trigeliserida.,using cholesterol method: CHOD-PAP (Cholesterol Oxidase-Peroxidase Aminoantipyrine Phenol). The results showed that total DGAT1 did not significantly affect to blood cholesterol level. Of the three DGAT genotypes, the CC group had the lowest total cholesterol levels, compared to the other groups, while the triglyceride levels were low in the TT genotype, but not significantly different from the CC and CT genotypes. Keywords : Padjadjaran sheep, DGAT1, Choleseterol


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