scholarly journals Effect of the addition of Moringa Oleifera to fruit drinks on clinical parameters associated with iron deficiency anaemia in schoolchildren

2019 ◽  
Vol 69 (1) ◽  
pp. 2-11
Author(s):  
Karen Piedad Martínez Marciales ◽  
Javier Andrés Soto ◽  
Jhoalmis Sierra Castrillo ◽  
Jonathan Gonzalo Olivieri Moncada ◽  
Jaizul Carolina Galeano Arias ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Red Blood Cells ◽  
Low Income ◽  
Blood Cells ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Moringa Oleifera ◽  
Clinical Parameters ◽  
Economic Implications ◽  
Deficiency Anaemia

Worldwide, iron deficiency anaemia (IDA) is one the most significant nutritional maladies, especially in low and middle-income countries. This is mainly due to the associated morbidity, economic implications on the health system and the welfare state. One of the most prevalent causes of IDA in children is insufficient food intake, which has an obvious connection with the social environment. The main strategy in the management of this condition is counteracting such deficiency through the improvement of nutrition and family upbringing. Aiming to explore affordable, novel and straightforward approaches to treat this nutritional condition, we developed a descriptive study associated with the incorporation of Moringa Oleifera in homemade fruit beverages delivered to 32 children from low-income families, in order to assess the evolution of IDA, evaluating specific clinical parameters such as red blood cells volume, as well as hemoglobin, ferritin and serum iron levels, within a two months lapse. At the end of this period, we observed a significant statistical rise in the levels of all the assessed parameters, finding about a 1.3-fold increase in hemoglobin and ferritin levels and in red blood cells volume; serum iron was 1.1 times higher. These findings are demonstrative of the wide spectrum of the medicinal features of Moringa and establish a promising and accessible strategy easy to incorporate into the diet of families of children suffering this pathology. La anemia ferropénica (AF) es una de las carencias nutricionales más significativas a nivel mundial, especialmente en los países de bajos y medios ingresos, debido principalmente a la morbilidad asociada, las implicaciones en el sistema de salud y el estado de bienestar. Una de las causas más frecuentes de esta deficiencia en los niños es la ingesta insuficiente, que tiene una evidente conexión con el entorno social. La principal estrategia en el manejo de esta afección es contrarrestar esta deficiencia a través de la mejora de la nutrición y la educación familiar. Con el objetivo de explorar enfoques asequibles, novedosos y directos para el tratamiento de esta enfermedad, se desarrolló un estudio descriptivo asociado a la incorporación de la Moringa Oleifera en bebidas de frutas caseras que se suministraron a 32 niños de familias de bajos ingresos para hacerle seguimiento a la evolución de la anemia por deficiencia de hierro, evaluando parámetros clínicos específicos como el volumen de células rojas y los niveles de hemoglobina, ferritina y hierro sérico en un lapso de dos meses. Se observó un aumento estadísticamente significativo en los niveles de todos los parámetros evaluados una vez finalizado el período de intervención. Al final del ensayo, observamos un aumento estadístico significativo en los niveles de todos los parámetros evaluados, encontrando un aumento de aproximadamente 1.3 veces en los niveles de hemoglobina y ferritina y en el volumen de los glóbulos rojos; el hierro sérico fue 1.1 veces mayor. Estos hallazgos son una demostración del amplio espectro de las características medicinales de la Moringa y establecen una estrategia prometedora y accesible, fácil de incorporar a la dieta de las familias de los niños que sufren esta patología.

scholarly journals AYUVEDIYA APPROCH TOWARD IRON DEFICIENCY ANAEMIA - A CASE STUDY

2021 ◽  
Vol 9 (5) ◽  
pp. 983-986
Author(s):  
Vd. Ruksar Piparvadiya ◽  
Keyword(s):  
Iron Deficiency ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Iron Deficiency Anaemia ◽  
Common Type ◽  
Shortness Of Breath ◽  
Deficiency Anaemia

Iron deficiency anaemia is a common type of anaemia – a condition in which blood lacks adequate healthy red blood cells. Anaemia symptoms like leave tired and shortness of breath. In Ayurveda, this can considered under the heading Pandu roga. A case of Iron deficiency anaemia with Ayurveda treatment was discussed here.

scholarly journals Implementation of a red blood cell-optical (RBO) channel for detection of latent iron deficiency anaemia by automated measurement of autofluorescence-emitting red blood cells

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Takahiro Tougan ◽  
Sawako Itagaki ◽  
Yuji Toya ◽  
Kinya Uchihashi ◽  
Toshihiro Horii
Keyword(s):  
Iron Deficiency ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Iron Deficiency Anaemia ◽  
Aminolevulinic Acid ◽  
Nutritional Disorder ◽  
Deficiency Anaemia ◽  
Iron Deficient ◽  
Latent Iron Deficiency

Abstract Iron deficiency is the most common and widespread nutritional disorder worldwide. The automated haematology analyser XN-30 (Sysmex, Kobe, Japan) was developed to detect malaria-infected red blood cells (RBCs) in human blood samples using flow cytometry. The optical system of the analyser detects autofluorescence (AF)-emitting RBCs containing iron-deficient haem groups and would aid in the diagnosis of anaemia resulting from iron deficiency. Here, an RBC-optical (RBO) channel was devised and implemented on the analyser. In vitro analyses showed that the analyser detected AF-emitting RBCs treated with 5-aminolevulinic acid. Furthermore, the analyser detected AF-emitting RBCs in mice fed a low iron diet and infected with a rodent malaria parasite; it could also be effectively used in humans. This study demonstrates that the analyser can quantitatively and reproducibly detect AF-emitting RBCs and measure other haematological parameters, suggesting its usefulness for the initial evaluation of latent iron deficiency anaemia in conjunction with the diagnosis of malaria.

scholarly journals A study to assess the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia

2020 ◽  
Vol 11 (2) ◽  
pp. 2288-2293
Author(s):  
Bhuvaneswari G.
Keyword(s):  
Iron Deficiency ◽  
Adolescent Girls ◽  
Biochemical Markers ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Control Group ◽  
Deficiency Anaemia ◽  
Post Test ◽  
And Control ◽  
Experimental Group

WHO Global Database on Anaemia for 1993-2005, covering almost half of the world’s population, estimated the prevalence of anaemia worldwide at 25 per cent.The aim of the study is to determine the effectiveness of honey dates amla mix on biochemical markers among adolescent girls with Iron deficiency anaemia. Quantitative experimental and control group pre and post-test design was used in this study. The study was conducted among adolescent girls in two different residential homes. Total study population is 170 adolescent girls were selected by simple random sampling technique. 85 adolescents girls were assigned to the experimental group and 85 participants in control group. For experimental group honey dates amla mix was given for 3 months whereas in  the control group iron and folic acid supplementation were provided. The study results shows that pre and post-test intervention scores of control and experimental group were compared by Wilcoxon scores rank test. Comparison of pre-test and post-test scores of severity of anemia, clinical variables, and level of fatigue and level of satisfaction, bio chemical parameters (reticulocytes, MCV, haematocrite, serum iron, serum ferritin, TIBC) were assessed in both experimental and control group. Between the experimental and control group (unpaired‘t’ test) reticulocytes, mcv, heamatocrite, serum iron serum ferritin showed significant changes in the pre test and post-test but there is no changes in TIBC. The study concluded that alternative nutritional therapy was effective for enhancing the blood heamoglobin & biochemical paramteres level, decreased the clinical variables and fatigue level among the adolescent girls with iron deficiency anemia.

scholarly journals Reducing iron deficiency anaemia due to heavy menstural blood loss in Nigerian rural adolescents. Reprinted from Public Health Nutrition Volume 1 (4), 249–257, 1998

2005 ◽  
Vol 8 (5) ◽  
pp. 451-460
Author(s):  
Fiona Barr ◽  
Loretta Brabin ◽  
Shola Agbaje ◽  
Feikumo Buseri ◽  
John Ikimalo ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Cultural Barriers ◽  
Menstrual Disorders ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Deficiency Anaemia

AbstractObjectiveMenstrual disorders are common in young women, and heavy menstrual blood losses (MBL) are an important cause of anaemia. Menstrual morbidity normally goes untreated in developing countries where cultural barriers also serve to make the problems. We investigated the prevelance of menstrual morbidity, and measured MBL and its relationship to iron deficiency in a rural adolescent population. The rationale was to assess whether or not reducing heavy MBL could be part of a strategy to reduce iron deficiency anaemia.SettingRural village in south-east Nigeria.DesignCross-sectional survey.SubjectsThe studdy included all non-pregnant, unmarried nulliparous girls (< 20 years) who had menstruated, and who lived in K'Dere village.MethodsA field worker allocated to each girl completed a questionnaire, and supervised recovery and collection of soiled pads and ensured blood sampling. MBL was measured using the standard alkaline haematin method. Haemoglobin (HB), serum iron, transferin saturation and protoporphyrin levels (ZPP) were also measured.Results307 girls completed MBL measurements; 11.9% refused to participate. 12.1% had menorrhagia (> 80 ml);. median MBL was 33.1 ml. Menorrhagia was more frequent in girls who had menstruated for > 2 years (p = 0.048), and had longer duration of meneses (p < 0.001). Iron status as measured by haematocrit, serum iron, transferrin saturation and ZPP values was inversely related to MBL. Neither height nor body mass index for age was associated with current iron status.ConclusionsThe level of menorrhagia detected (12%) may be an ‘expected’ level for a condition which often has no underlying pathology. Heavy MBL is one of the most important factors contributing to iron deficiency anaemia. Measures are needed to alleviate menstrual disorders and improve iron status. Oral contraceptives can be part of a strategy to reduce anaemia, particularly for adolescents at high risk of unwanted pregnancies.

PREVALENCE OF IRON-DEFICIENCY ANAEMIA IN BRAZILIAN CHILDREN UNDER FIVE YEARS OF AGE: A SYSTEMATIC REVIEW AND META-ANALYSIS

2020 ◽  
pp. 1-29
Author(s):  
Victor N.C. Silveira ◽  
Carolina A. Carvalho ◽  
Poliana C.A.F. Viola ◽  
Elma I.S. Magalhães ◽  
Luana L. Padilha ◽  
...  
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Low Income ◽  
Iron Deficiency Anaemia ◽  
Meta Analysis ◽  
Deficiency Anaemia ◽  
Children Under Five ◽  
Under Five ◽  
Pooled Prevalence ◽  
Brazilian Children

Abstract Iron-deficiency anaemia is considered an important public health problem both in wealthier countries and in those of medium and low income, especially in children under five years of age. The shortage of studies with national representativity in medium income countries, such as Brazil, prevents the knowledge of the current situation and its associated factors. We conducted a systematic review and meta-analysis to estimate the pooled prevalence of iron-deficiency anaemia in Brazilian children under five years of age and determined the factors involved in the variability of the estimates of prevalence. We collected 57 studies from the databases MEDLINE, LILACS, and Web of Science, along with the reference lists of included articles. We contacted authors for unpublished data. We did not restrict publication timespan and language. This systematic review and meta-analysis were reported according to the guidelines by PRISMA. The pooled prevalence of anaemia in children under five years of age in Brazil was 40.2% (CI95%: 36.0-44.8). The age range of the child and the period of data collection were associated with the anaemia prevalence. The pooled prevalence of anaemia was higher in children under 24 month of age (53.5% vs 30.7%; p<0.001) and in studies with data collected before 2004 (51.8% vs 32.6%; p=0.001). The efforts made by Brazilian government were successful in the reduction of anaemia in children under five years old in Brazil in the evaluated period. However, prevalence remains beyond acceptable levels for this populational group.

scholarly journals Association between iron deficiency anaemia and simple febrile seizure in South Indian rural population

2020 ◽  
Vol 7 (12) ◽  
pp. 2355
Author(s):  
Gayathri Durai ◽  
Syamily Parambath ◽  
Rajendiran Ramachari Ramayi
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Febrile Seizure ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Febrile Seizures ◽  
Iron Level ◽  
Serum Iron Level ◽  
Deficiency Anaemia ◽  
South Indian

Background: Simple febrile seizure is a common problem worldwide, many studies have investigated the etiology and natural history of febrile seizures and evaluated various management strategies, but very little information is available about iron deficiency as a risk factor. Hence, we aimed to determine the association between iron deficiency anaemia and simple febrile seizures in south Indian rural population. Methods: It is an observational study done in paediatrics department at Sri Venkateshwaraa medical college hospital and research centre. A total 120 (60 cases and 60 control) were included in the study. Children with febrile seizures and controls were included fever without seizures. Informed consent was taken from parents of each child. Children were divided into two groups, cases and controls. Serum ferritin level, Hb, HCT and MCV levels were assessed.Results: Mean Hb level in cases and controls were 9.1±1.2 and 12.7±1.7 mg/dl respectively. Mean MCV value in cases and controls was 78.1±6.2 and 81.4±6.9 respectively. Mean serum iron level in cases was 29.9±4.9 and in controls mean serum iron level was 42.8±7.4. Conclusions: Iron deficiency anaemia is considered as a risk factor for febrile seizures in children.

scholarly journals Anaemia prevalence and its associated factors in children under 5 years in Western China: a systematic review

2022 ◽  
Vol 6 (1) ◽  
pp. e001185
Author(s):  
Yefan Du ◽  
Ying Liao ◽  
Fangqun Leng ◽  
Linhua Li ◽  
Ruixue Ye ◽  
...  
Keyword(s):  
Systematic Review ◽  
Iron Deficiency ◽  
Low Income ◽  
Associated Factors ◽  
Iron Deficiency Anaemia ◽  
Linear Trend ◽  
Western China ◽  
Cross Sectional ◽  
Deficiency Anaemia ◽  
Children Under 5

BackgroundIron-deficiency anaemia disproportionately affects children in low-income and middle-income areas; Western China is a prime example. Given the health risks associated with childhood anaemia and the large heterogeneity of published studies on this subject, we conducted a systematic review of the evidence regarding anaemia prevalence and associated factors in children under 5 years in Western China.MethodsWe searched for all relevant studies on the prevalence of iron deficiency anaemia in children under 5 years in Western China, obtaining research between 1 January 2011 and 30 June 2021, in English and Chinese from Medline, Embase, PubMed, Web of Science, CNKI, WanFang Data and VIP. Two reviewers independently screened titles and abstracts; three reviewed full texts of relevant articles for data extraction and performed quality assessments. The median prevalence was calculated on unweighted pooling, stratified by region, sex, age and ethnic group. Associated factors and a linear trend chart were conducted to identify trends and research highlights.ResultsAmong the 55 articles included, most were cross-sectional studies (39, 70.91%). The prevalence of anaemia in children under 5 years in Western China ranged from 3.69% to 75.74% (median 42.54% (IQR 25.62%–52.56%)); the highest levels were in Qinghai province: 59.10%–75.74% (median 67.80% (IQR 64.70%–72.75%)); the highest levels were reported in the subgroup of children aged 6–12 months (median 50.09% (IQR 34.35%–59.04%)). Regional contexts, individual sociodemographic characteristics and feeding behaviours, and nutritional programme interventions were factors associated with anaemia prevalence.ConclusionThe prevalence of anaemia in children under 5 years in Western China is concerningly high. For this multiethnic and economically underdeveloped region, more high-quality and prospective studies are needed to inform evidence based and targeted preventive strategies to decrease the high prevalence of anaemia among young children.

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