scholarly journals Antiaging Activity of Gel Preparation Containing Three Varieties of Passion Fruit Peel Ethanolic Extract

2020 ◽  
Vol 8 (A) ◽  
pp. 170-174
Author(s):  
Nazliniwaty Nazliniwaty ◽  
Fathur Rahman Harun ◽  
Effendy De Lux Putra ◽  
Nerdy Nerdy

BACKGROUND: Antiaging cosmetics are cosmetics that can prevent or correct the signs of premature aging. Passion fruit (Passiflora sp.) peel is an agricultural waste contains polyphenol compounds and flavonoids which are a source of natural antioxidants to prevent premature aging. The passion fruit peel extract formulated into gel preparations which can increase the economic value of the passion fruit peel waste. OBJECTIVE: The objective of the study was to test the antiaging activity of gel preparations containing ethanolic extracts of purple, red, and yellow passion fruit on experimental animal skins with several parameters (wrinkle, melanin, pore, moisture, and elasticity). METHODS: Gel was made by adding passion fruit peel extract with several concentrations (0.05%, 0.10%, 0.15%, 0.20%, and 0.25%) in gel base. The blank used is a gel base without extracts. Measurement of wrinkle, black pigment (melanin), pore size, moisture content, and elasticity was performed using a skin analyzer. The use of gel is done 2 times a day for 28 days. RESULTS: Gel with purple, red, and yellow passion fruit peel extract can be formulated into gel preparations. The higher concentration of passion fruit peel extract shows a higher antiaging activity. Gel preparations with purple, red, and yellow passion fruit peel extract, respectively, show the recovery of wrinkle 16.16%, 8.73%, and 6.49%; recovery of melanin 20.11%, 10.75%, and 8.06%; recovery of pore 18.78%, 10.15%, and 7.69%; recovery of moisture 32.74%, 17.70%, and 13.04%; and recovery of elasticity 30.08%, 16.13%, and 12.30%. CONCLUSIONS: The highest antiaging activity was given by gel preparations containing purple passion fruit peel extract and the lowest antiaging activity was given by gel preparations with yellow passion fruit peel extracts.

2019 ◽  
Vol 7 (4) ◽  
pp. 536-542 ◽  
Author(s):  
Nerdy Nerdy ◽  
Kiking Ritarwan

BACKGROUND: The Passion Fruit (Passiflora sp.) that grows in the Indonesian region generally has three varieties, namely purple passion fruit (Passiflora edulis Sims.), red passion fruit (Passiflora ligularis Juss.), and yellow passion fruit (Passiflora verrucifera Lindl.). The passion fruit peel is an economic waste that has not been utilised optimally, but has many efficacious phytochemical contents. AIM: The objectives of this research are to examine scientifically hepatoprotective activity (with paracetamol-induced hepatotoxic) and nephroprotective activity (with gentamicin-induced nephrotoxic) from three varieties of the passion fruit (purple passion fruit peel extract, red passion fruit peel extract and yellow passion fruit peel extract) in the albino rat (Rattus norvegicus). METHODS: Three varieties of passion fruit peels were extracted by maceration method. The experimental animals used were the albino rat (Rattus norvegicus). Hepatoprotective activity was done by the liver biochemical (alanine transaminase and aspartate transaminase) analysis with paracetamol (hepatotoxic compound) induced after 10 days of treatment with extract. Nephroprotective activity was done by the kidney biochemical (urea and creatinine) analysis with gentamicin (nephrotoxic compound) induced after 10 days of treatment with extract. RESULTS: The hepatoprotective activity for positive control was similar to the 250 mg of purple passion fruit peel extract per kg of body weight, 250 mg of red passion fruit peel extract per kg of body weight, and 500 mg of yellow passion fruit peel extract per kg of body weight. The nephroprotective activity for positive control (50 mg of silymarin per kg of body weight) was similar to the 250 mg of purple passion fruit peel extract per kg of body weight, 500 mg of red passion fruit peel extract per kg of body weight, and 500 mg of yellow passion fruit peel extract per kg of body weight. CONCLUSIONS: The extracts were shown hepatoprotective activity and nephroprotective activity with a dose-dependent activity. The hepatoprotective activity and nephroprotective activity of purple passion fruit peel extract were the best compared to red passion fruit peel extract and yellow passion fruit peel extract.


2008 ◽  
Vol 121 (2) ◽  
pp. S221-S221
Author(s):  
R FARID ◽  
S ZIBADI ◽  
H RAFATPANAH ◽  
F JABBARI ◽  
R GHASEMI ◽  
...  

Author(s):  
Dhuha Itsnanisa Adi

<p>ABSTRAK</p><p>Latar Belakang: Rasio LDL terhadap HDL menggambarkan profil kolesterol LDL dan HDL dalam darah dan merupakan salah satu komponen penting sebagai indikator risiko penyakit kardiovaskular. Kandungan serat yang tinggi terutama pektin (serat larut air) pada kulit markisa kuning dapat mencegah penyerapan karbohidrat, menurunkan absorpsi lemak dan kolesterol darah sehingga dapat mengontrol kadar lipid dalam darah.</p><p>Tujuan: Penelitian ini bertujuan menilai pengaruh jus kulit markisa kuning terhadap rasio kolesterol LDL:HDL pada pasien diabetes mellitus sebagai prediktor penyakit kardiovaskuler di wilayah kerja puskesmas Teppo Kabupaten Pinrang.</p><p>Metode: Jenis penelitian ini adalah quasi eksperimen dengan rancangan non-randomized pre-test dan post-test with control group. Cara pemilihan sampel dengan metode purposive sampling sebanyak 40 orang yang dibagi dalam 2 kelompok. Kelompok perlakuan diberikan jus kulit markisa kuning sebanyak 250 ml/hari dan edukasi selama 15 hari sedangkan kelompok kontrol hanya diberikan edukasi.</p><p>Hasil: Hasil penelitian ini menunjukkan bahwa rasio kolesterol LDL: HDL pada kelompok intervensi mengalami penurunan dengan rerata penurunan sebesar 0,56 sedangkan pada kelompok kontrol mengalami peningkatan dengan rerata peningkatan sebesar 0,25. Secara statistik menunjukkan adanya perbedaan antara kelompok intervensi dan kelompok control (p&lt; 0,05).</p><p>Kesimpulan: Dengan demikian terdapat perbedaan yang signifikan rerata selisih rasio kolesterol LDL:HDL antara kelompok intervensi dan kelompok kontrol setelah pemberian jus kulit markisa kuning pada penderita diabetes mellitus.</p><p>KATA KUNCI: kulit markisa kuning; rasio LDL:HDL; prediktor penyakit kardiovaskuler</p><p>ABSTRACT</p><p>Background: The ratio of LDL to HDL illustrates the profile of LDL and HDL cholesterol in the blood and it is one of the important components as an indicator of risk for cardiovascular disease. High fiber content, especially pectin (water-soluble fiber) on the skin of yellow passion fruit can prevent the absorption of carbohydrates, reduce the absorption of fat and blood cholesterol so that it can control blood lipid levels.</p><p>Objectives: To assess the effect of fruit peel juice on LDL to HDL cholesterol ratio in patients with diabetes mellitus as predictors of cardiovascular disease in the working area of Teppo Health Center, Pinrang Regency.</p><p>Methods: This study was a quasi-experimental design with a non-randomized pre-test and post-test with the control group. The method of selecting samples with a purposive sampling method of 40 people divided into 2 groups. The treatment group was given 250 ml of yellow passion fruit peel juice /day and education for 15 days while the control group was given education only.</p><p>Results: The result showed that LDL to HDL cholesterol ratio in the intervention group decreased about 0.56 while in contrast LDL to HDL cholesterol ratio in the control group increased about 0.25 and statistically, the change was the difference (p&gt; 0.05).</p><p>Conclussion: Thus there is a significant difference in the mean LDL to HDL cholesterol ratio between the intervention group and the control group after administration of yellow passion fruit skin juice in people with diabetes mellitus.</p><p>KEYWORDS: Yellow passion fruit peel juice; LDL to HDL cholesterol ratio; predictor of cardiovascular disease</p>


2008 ◽  
Vol 28 (3) ◽  
pp. 166-171 ◽  
Author(s):  
Ronald Ross Watson ◽  
Sherma Zibadi ◽  
Houshang Rafatpanah ◽  
Farahzad Jabbari ◽  
Ramin Ghasemi ◽  
...  

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