scholarly journals Developing DNA Based Methods for Environmental Regulation and Management- UK Insights

2021 ◽  
Vol 4 ◽  
Author(s):  
Willie Duncan

DNA assessments are revolutionising biomonitoring opportunities across the globe, including the monitoring of rare and invasive species, creating biodiversity inventories, and developing pollution diagnostic and ecosystem resilience assessment methods. To date pollution and ecosystem resilience assessments have been based on assessing the diversity of familiar taxonomic groups but the introduction of DNA based methods will significantly increase the opportunities to exploit groups not previously used for this work. Environmental regulators and managers can derive many benefits from the adoption of these methods, such as improved understanding of environmental conditions, cost effective sample processing, overcoming taxonomic bottlenecks, either through shortages in trained taxonomists or utilising biota with challenging taxonomies. In addition to creating diversity based metrics DNA monitoring also allows for the assessment of functional attributes such as those that support important ecosystem services. The UK has been an early adopter of this technology and this paper will explore how the alignment of scientific advances have coincided with operational needs to create a fertile arena for the development of DNA based assessment methods that will be used in environmental regulation and management. Development projects advanced in the UK will be examined to identify the common and specific issues associated with them that have led to early engagement and adoption.

Author(s):  
Tochukwu Moses ◽  
David Heesom ◽  
David Oloke ◽  
Martin Crouch

The UK Construction Industry through its Government Construction Strategy has recently been mandated to implement Level 2 Building Information Modelling (BIM) on public sector projects. This move, along with other initiatives is key to driving a requirement for 25% cost reduction (establishing the most cost-effective means) on. Other key deliverables within the strategy include reduction in overall project time, early contractor involvement, improved sustainability and enhanced product quality. Collaboration and integrated project delivery is central to the level 2 implementation strategy yet the key protocols or standards relative to cost within BIM processes is not well defined. As offsite construction becomes more prolific within the UK construction sector, this construction approach coupled with BIM, particularly 5D automated quantification process, and early contractor involvement provides significant opportunities for the sector to meet government targets. Early contractor involvement is supported by both the industry and the successive Governments as a credible means to avoid and manage project risks, encourage innovation and value add, making cost and project time predictable, and improving outcomes. The contractor is seen as an expert in construction and could be counter intuitive to exclude such valuable expertise from the pre-construction phase especially with the BIM intent of äóÖbuild it twiceäó», once virtually and once physically. In particular when offsite construction is used, the contractoräó»s construction expertise should be leveraged for the virtual build in BIM-designed projects to ensure a fully streamlined process. Building in a layer of automated costing through 5D BIM will bring about a more robust method of quantification and can help to deliver the 25% reduction in overall cost of a project. Using a literature review and a case study, this paper will look into the benefits of Early Contractor Involvement (ECI) and the impact of 5D BIM on the offsite construction process.


Author(s):  
Pete Dale

Numerous claims have been made by a wide range of commentators that punk is somehow “a folk music” of some kind. Doubtless there are several continuities. Indeed, both tend to encourage amateur music-making, both often have affiliations with the Left, and both emerge at least partly from a collective/anti-competitive approach to music-making. However, there are also significant tensions between punk and folk as ideas/ideals and as applied in practice. Most obviously, punk makes claims to a “year zero” creativity (despite inevitably offering re-presentation of at least some existing elements in every instance), whereas folk music is supposed to carry forward a tradition (which, thankfully, is more recognized in recent decades as a subject-to-change “living tradition” than was the case in folk’s more purist periods). Politically, meanwhile, postwar folk has tended more toward a socialist and/or Marxist orientation, both in the US and UK, whereas punk has at least rhetorically claimed to be in favor of “anarchy” (in the UK, in particular). Collective creativity and competitive tendencies also differ between the two (perceived) genre areas. Although the folk scene’s “floor singer” tradition offers a dispersal of expressive opportunity comparable in some ways to the “anyone can do it” idea that gets associated with punk, the creative expectation of the individual within the group differs between the two. Punk has some similarities to folk, then, but there are tensions, too, and these are well worth examining if one is serious about testing out the common claim, in both folk and punk, that “anyone can do it.”


Author(s):  
Isabel Hadley

BS 7910, the UK procedure for the assessment of flaws in metallic structures, was first published almost 30 years ago in the form of a fracture/fatigue assessment procedure, PD6493. It provided the basis for analysing fabrication flaws and the need for repair in a rational fashion, rather than relying on long-established (and essentially arbitrary) workmanship rules. The UK offshore industry in particular embraced this new approach to flaw assessment, which is now widely recognised by safety authorities and specifically referred to in certain design codes, including codes for pressure equipment. Since its first publication in 1980, PD6493/BS 7910 has been regularly maintained and expanded, taking in elements of other publications such as the UK power industry’s fracture assessment procedure R6 (in particular the Failure Assessment Diagram approach), the creep assessment procedure PD6539 and the gas transmission industry’s approach to assessment of locally thinned areas in pipelines. The FITNET European thematic network, run between 2002 and 2006, has further advanced the state of the art, bringing in assessment methods from SINTAP (an earlier European research project), R6, R5 and elsewhere. In particular, the FITNET fracture assessment methods represent considerable advances over the current BS 7910 methods; for example, weld strength mismatch can be explicitly analysed by using FITNET Option 2, and crack tip constraint through Option 5. Corrosion assessment methods in FITNET are also more versatile than those of BS 7910, and now include methods for vessels and elbows as well as for pipelines. In view of these recent advances, the BS 7910 committee has decided to incorporate many elements of the FITNET procedure into the next edition of BS 7910, to be published c2012. This paper summarises the history of the development of BS 7910, its relationship with other flaw assessment procedures (in particular FITNET and R6) and its future.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Emily Joanne Nixon ◽  
Ellen Brooks-Pollock ◽  
Richard Wall

Abstract Background Ovine psoroptic mange (sheep scab) is a highly pathogenic contagious infection caused by the mite Psoroptes ovis. Following 21 years in which scab was eradicated in the UK, it was inadvertently reintroduced in 1972 and, despite the implementation of a range of control methods, its prevalence increased steadily thereafter. Recent reports of resistance to macrocyclic lactone treatments may further exacerbate control problems. A better understanding of the factors that facilitate its transmission are required to allow improved management of this disease. Transmission of infection occurs within and between contiguous sheep farms via infected sheep-to-sheep or sheep–environment contact and through long-distance movements of infected sheep, such as through markets. Methods A stochastic metapopulation model was used to investigate the impact of different transmission routes on the spatial pattern of outbreaks. A range of model scenarios were considered following the initial infection of a cluster of highly connected contiguous farms. Results Scab spreads between clusters of neighbouring contiguous farms after introduction but when long-distance movements are excluded, infection then self-limits spatially at boundaries where farm connectivity is low. Inclusion of long-distance movements is required to generate the national patterns of disease spread observed. Conclusions Preventing the movement of scab infested sheep through sales and markets is essential for any national management programme. If effective movement control can be implemented, regional control in geographic areas where farm densities are high would allow more focussed cost-effective scab management. Graphical Abstract


Author(s):  
Anmol Arora ◽  
Andrew Wright ◽  
Mark Cheng ◽  
Zahra Khwaja ◽  
Matthew Seah

AbstractHealthcare as an industry is recognised as one of the most innovative. Despite heavy regulation, there is substantial scope for new technologies and care models to not only boost patient outcomes but to do so at reduced cost to healthcare systems and consumers. Promoting innovation within national health systems such as the National Health Service (NHS) in the United Kingdom (UK) has been set as a key target for health care professionals and policy makers. However, while the UK has a world-class biomedical research industry, several reports in the last twenty years have highlighted the difficulties faced by the NHS in encouraging and adopting innovations, with the journey from idea to implementation of health technology often taking years and being very expensive, with a high failure rate. This has led to the establishment of several innovation pathways within and around the NHS, to encourage the invention, development and implementation of cost-effective technologies that improve health care delivery. These pathways span local, regional and national health infrastructure. They operate at different stages of the innovation pipeline, with their scope and work defined by location, technology area or industry sector, based on the specific problem identified when they were set up. In this introductory review, we outline each of the major innovation pathways operating at local, regional and national levels across the NHS, including their history, governance, operating procedures and areas of expertise. The extent to which innovation pathways address current challenges faced by innovators is discussed, as well as areas for improvement and future study.


BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e021256 ◽  
Author(s):  
Estela Capelas Barbosa ◽  
Talitha Irene Verhoef ◽  
Steve Morris ◽  
Francesca Solmi ◽  
Medina Johnson ◽  
...  

ObjectivesTo evaluate the cost-effectiveness of the implementation of the Identification and Referral to Improve Safety (IRIS) programme using up-to-date real-world information on costs and effectiveness from routine clinical practice. A Markov model was constructed to estimate mean costs and quality-adjusted life-years (QALYs) of IRIS versus usual care per woman registered at a general practice from a societal and health service perspective with a 10-year time horizon.Design and settingCost–utility analysis in UK general practices, including data from six sites which have been running IRIS for at least 2 years across England.ParticipantsBased on the Markov model, which uses health states to represent possible outcomes of the intervention, we stipulated a hypothetical cohort of 10 000 women aged 16 years or older.InterventionsThe IRIS trial was a randomised controlled trial that tested the effectiveness of a primary care training and support intervention to improve the response to women experiencing domestic violence and abuse, and found it to be cost-effective. As a result, the IRIS programme has been implemented across the UK, generating data on costs and effectiveness outside a trial context.ResultsThe IRIS programme saved £14 per woman aged 16 years or older registered in general practice (95% uncertainty interval −£151 to £37) and produced QALY gains of 0.001 per woman (95% uncertainty interval −0.005 to 0.006). The incremental net monetary benefit was positive both from a societal and National Health Service perspective (£42 and £22, respectively) and the IRIS programme was cost-effective in 61% of simulations using real-life data when the cost-effectiveness threshold was £20 000 per QALY gained as advised by National Institute for Health and Care Excellence.ConclusionThe IRIS programme is likely to be cost-effective and cost-saving from a societal perspective in the UK and cost-effective from a health service perspective, although there is considerable uncertainty surrounding these results, reflected in the large uncertainty intervals.


Pythagoras ◽  
2009 ◽  
Vol 0 (69) ◽  
Author(s):  
Sarah Bansilal

The Common Tasks for Assessment (CTA) was a new assessment programme that was introduced in 2002 in South Africa for all Grade 9 learners. The purpose of this paper is to articulate some concerns around the use of contextualised assessment activities in the CTA. The study reported here was carried out in 2003. Data for the study was generated from lesson observations and interviews with the participant teachers and groups of learners. It is argued that although the intentions behind the design of the CTA are well meaning and noble, there are in fact some learners who may be unintentionally disadvantaged by the design of the CTA which uses an extended context as a source for all the assessment tasks. In this paper two unintended consequences of using ‘real life’ contexts are identified and the implications of these are discussed, by linking the observations to research carried out in the UK and the USA.


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