THE EFFECT OF DISPLACEMENT RATE ON VISCOELASTIC PROPERTIES OF RAT CERVIX
Determining the viscoelastic response of cervix at different displacement rates can provide sufficient information for the normal mechanical behavior of the tissue in assessment of cervical insufficiency. The objective of this study was to investigate the effect of displacement rate on viscoelastic properties of rat cervix. Different displacement rates were employed to measure the tensile and load-relaxation properties of cervices from virgin and 16 days post-conception pregnant rats. After preconditioning, the displacement of 2[Formula: see text]mm was applied to the distal halves of five pregnant rat’s cervices and 1 millimeter to the five virgin samples circumferentially. Uniaxial tension tests were employed at the displacement rates of 0.01, 0.1 and 1 mm/s randomly and were held for 10 min while the tissues were relaxed. Tensile and load-relaxation curves were well described by a quasi-linear viscoelastic model. Statistical analysis revealed significant correlation between the change in displacement rate and the elastic response, as well as the viscous response of the virgin samples. For pregnant samples, though, the correlation was found significant between the displacement rate and the elastic response of the tissue. Virgin tissue is strongly viscoelastic. Quantitative measurements of cervical mechanical properties will lead to a more accurate assessment of cervical insufficiency and prediction of preterm birth.