Stratagems of Nanotechnology Augmenting the Bioavailability and Therapeutic Efficacy of Traditional Medicine to Formulate Smart Herbal Drugs Combating

2017 ◽  
pp. 1780-1804
Author(s):  
Anita Margret
Keyword(s):  
Mental Health ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Global Burden ◽  
Emotional States ◽  
Herbal Drugs ◽  
Active Components ◽  
Scientific Analysis ◽  
Mental Abilities ◽  
Herbal Formulations

Mental illness is one of the most fundamental emotional states of conscious being which becomes unbalanced and leads to neurological disorders. It is a significant contributor to the global burden of disease and there is a strong desire to devise a remedy. Ayurveda represents a traditional medicine system of India that endorses antiquity than western medicine and relies on formulations rather than their active components. It has categorised a group of herbal medicines to improve mental abilities. Conversely, the mechanistic details of the therapy are not available in ayurvedic literature and there is a need to fortify this system with modern scientific analysis. The design of nanosystems encompasses promising characteristics in the field of drug delivery with a limited dosage thereby decreasing adverse effects. This chapter confers stratagems of devising polymeric nano herbal formulations as smart nano brain drugs to espouse mental health.

Stratagems of Nanotechnology Augmenting the Bioavailability and Therapeutic Efficacy of Traditional Medicine to Formulate Smart Herbal Drugs Combating

2017 ◽  
pp. 250-282
Author(s):  
Anita Margret
Keyword(s):  
Mental Health ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Global Burden ◽  
Emotional States ◽  
Herbal Drugs ◽  
Active Components ◽  
Scientific Analysis ◽  
Mental Abilities ◽  
Herbal Formulations

Mental illness is one of the most fundamental emotional states of conscious being which becomes unbalanced and leads to neurological disorders. It is a significant contributor to the global burden of disease and there is a strong desire to devise a remedy. Ayurveda represents a traditional medicine system of India that endorses antiquity than western medicine and relies on formulations rather than their active components. It has categorised a group of herbal medicines to improve mental abilities. Conversely, the mechanistic details of the therapy are not available in ayurvedic literature and there is a need to fortify this system with modern scientific analysis. The design of nanosystems encompasses promising characteristics in the field of drug delivery with a limited dosage thereby decreasing adverse effects. This chapter confers stratagems of devising polymeric nano herbal formulations as smart nano brain drugs to espouse mental health.

scholarly journals Stratagems of Nanotechnology Augmenting the Bioavailability and Therapeutic Efficacy of Traditional Medicine to Formulate Smart Herbal Drugs Combating

2017 ◽  
pp. 1367-1392
Author(s):  
Anita Margret
Keyword(s):  
Mental Health ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Global Burden ◽  
Emotional States ◽  
Herbal Drugs ◽  
Active Components ◽  
Scientific Analysis ◽  
Mental Abilities ◽  
Herbal Formulations

Mental illness is one of the most fundamental emotional states of conscious being which becomes unbalanced and leads to neurological disorders. It is a significant contributor to the global burden of disease and there is a strong desire to devise a remedy. Ayurveda represents a traditional medicine system of India that endorses antiquity than western medicine and relies on formulations rather than their active components. It has categorised a group of herbal medicines to improve mental abilities. Conversely, the mechanistic details of the therapy are not available in ayurvedic literature and there is a need to fortify this system with modern scientific analysis. The design of nanosystems encompasses promising characteristics in the field of drug delivery with a limited dosage thereby decreasing adverse effects. This chapter confers stratagems of devising polymeric nano herbal formulations as smart nano brain drugs to espouse mental health.

scholarly journals Recent development in novel drug delivery systems for delivery of herbal drugs: An updates

2021 ◽  
Vol 8 (2) ◽  
pp. 008-018
Author(s):  
Prajakta N. Dongare ◽  
Anuja S. Motule ◽  
Mahesh R. Dubey ◽  
Manisha P. More ◽  
Prerna A. Patinge ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Herbal Medicines ◽  
Delivery Systems ◽  
Therapeutic Effects ◽  
Herbal Drugs ◽  
Active Components ◽  
Novel Drug ◽  
Herbal Formulations

In the recent years, herbal medicines have gained worldwide attention of peoples and researchers due to their esthetic value, more patient’s compliance and prominent therapeutic effects. Novel drug delivery systems for delivery of herbal drugs possesses several advantages over conventional formulations. It includes enhancement of solubility, bioavailability, and protection from toxicity, etc. The herbal drugs can be used in a more upright course with enhanced efficacy by incorporating them into suitable dosage forms. This can be achieved by designing novel drug delivery systems for such drugs. Such systems are polymeric nanoparticles, nanocapsules, phytosomes, animations, microsphere, etc. The present article highlights the current condition of the development of novel herbal formulations and summarizes their type of active components, biological activity, and applications of novel formulations.

Nano Phytomedicine Based Delivery System for CNS Disease

2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Low Cost ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Widespread Acceptance ◽  
The Central Nervous System ◽  
Low Toxicity ◽  
Ancient Times ◽  
Plant Sources ◽  
Herbal Formulations

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.

scholarly journals Standardization of Herbal Drugs – A Overview

2021 ◽  
Vol 68 (1) ◽  
Author(s):  
D. Umamaheswari ◽  
R. Muthuraja ◽  
M. Kumar ◽  
B.S. Venkateswarlu
Keyword(s):  
Medicinal Plants ◽  
Raw Materials ◽  
Herbal Medicines ◽  
Therapeutic Agents ◽  
Pharmaceutical Manufacturing ◽  
Quality Assurance Program ◽  
Herbal Drugs ◽  
Quantitative Analyses ◽  
Herbal Formulations ◽  
Dosage Formulation

The medicinal plants are important source for pharmaceutical manufacturing. Medicinal plants & herbal medicines account for a significant percentage of the pharmaceutical market. As the side effects of Synthetic medicine have started getting more apparent, majority of formulation are prepared from herbs. The herbal medicines however, suffer from lack of standardization parameters. The main limitation is the lack of standardization of raw materials, of processing methods and of the final products, dosage formulation, and the non existence of criteria for quality control. Herbal formulations have reached extensive acceptability as therapeutic agents for several diseases. The development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analyses of marker/bioactive compounds and other major constituents, is a major challenge to scientists. Standardization is an important step for the establishment of a consistent biological activity, a consistent chemical profile, or simply a quality assurance program for production and manufacturing of herbal drugs.

Nanotechnology based herbal formulations: A survey of recent patents, advancements and transformative headways

2021 ◽  
Vol 15 ◽  
Author(s):  
Anureet Kaur ◽  
Lakhvir Kaur ◽  
Gurjeet Singh ◽  
RK Dhawan ◽  
Ayushi Mahajan
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Adverse Effects ◽  
Traditional Medicine ◽  
Synergistic Effects ◽  
Complete Information ◽  
Review Article ◽  
Innovative Technology ◽  
Herbal Drugs ◽  
Herbal Formulations

: Nanotechnology in association with the herbal medicine can lead to enhanced therapeutic and diminished adverse effects of medication. In turn, it can lead to synergistic effects of administered compound overcoming its demerits. Now-a-days, the trend of herbal compounds to treat even a small illness is gaining momentum. Gone are the days when the ineffectiveness of a compound was impossible to be dealt with. Nevertheless, in this competitive era of science and innovative technology, it has become possible to maximize the usefulness of ineffective yet potent herbal compounds. The demand of herbal compounds is getting amplified because of their ability to treat myriad of diseases including COVID-19, showing less side effects. The merger of nanotechnology with traditional medicine augments the potential of herbal drugs for devastating dangerous and chronic diseases like cancer. In this review article, we have tried to assimilate the complete information regarding the use of different nanocarriers to overcome the drawbacks of herbal compounds. In addition, all the recent advancements in the herbal field as well as the future exploration to be emphasized have been discussed.

scholarly journals Saraswati Panchak – A Novel Herbal Combination for Mental Health

2021 ◽  
Vol 3 (2) ◽  
pp. 09-18
Author(s):  
Ruchi Singh
Keyword(s):  
Mental Health ◽  
Quality Control ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Complete Analysis ◽  
Herbal Drugs ◽  
Active Constituent ◽  
Coarse Powder ◽  
Physico Chemical ◽  
History Of

Herbal medicines have a history of long therapeutic use and are still serving a lot of the health needs of a big population of the world. However, the quality control still remains a challenge because of the variation of chemical constituents involved. There are numerous compounds in herbal drugs that are in complex matrices in which no single active constituent is responsible for the overall efficacy. This creates a challenge in establishing quality control standards and standardization of finished herbal drugs. Saraswati Panchak is a novel combination given by Pandit Shri Ram Sharma Acharya for mental health. In this study, components of this novel herbal combination were explained for its potential utility in mental illness. In addition, the study also detailed how Saraswati Panchak Churna was converted into tablet form to increase the shelf life, make it easy to dispense, for dose fixation, etc. The tablet was subjected to organoleptic analysis and physico-chemical analysis to establish its efficacy. After performing complete analysis it was found that all the parameters are within the range. The coarse powder of these herbs may be used as havan samagri in brain related disorders because of the presence of nootropic herbs.

scholarly journals Whether Herbal Medicines Play an Important Role in the COVID-19 Therapeutics and Boosting Immune as One of the Preventive Solutions: A Science Opinion

2020 ◽  
Vol 6 (1) ◽  
pp. 1-3
Author(s):  
Quang Ung Le ◽  
◽  
Horng Liang Lay ◽  
Keyword(s):  
Quality Of Life ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Health Related Quality ◽  
Practical Application ◽  
Related Quality ◽  
Health Related

The coronavirus disease 2019 (COVID-19) epidemic affects people’s health and health-related quality of life. Based on our knowledge on traditional medicine, we discussed the topic: whether herbal medicines play an important role in the COVID-19 therapeutics and immune enhancing as a preventive solution. The new studies on efficacy and practical application of herbs in the COVID-19 therapeutics and producing immediate herbal drugs are encouraged.

Comparative Study of the Biologically Active Substances Composition and Content in Meadowsweet (Filipendula ulmaria (L.) Maxim) Crude Herbal Drugs (Herb, Leafs, Flowers) of Russian Origin

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Dmitry Olegovich Bokov ◽  
Tatyana Yuryevna Kovaleva ◽  
Valentina Alekseevna Ermakova ◽  
Daria Aleksandrovna Trashchenkova ◽  
Ekaterina Anatolievna Dorovskih ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Neurotropic Activity ◽  
Comparative Investigation ◽  
Biologically Active ◽  
Total Flavonoids ◽  
Herbal Drugs ◽  
Filipendula Ulmaria ◽  
Pharmacopoeial Monograph ◽  
Total Extractives ◽  
Layer Chromatography

Filipendula ulmaria (L.) Maxim. (Meadowsweet) is known in traditional medicine as anti-inflammatory, wound-healing,astringent and antibacterial remedy. However recent studies show that it also has neurotropic activity. In Russia meadowsweet flowers are used as crude herbal drugs (temporary pharmacopoeial monograph 42-1777-87), also leafs and herb are used in the traditional medicine. Objective of the study was to carry out comparative investigation of composition and content of major biologically active compounds (BAC) in Filipendula ulmaria herb, flowers and leafs by thin-layer chromatography, differential spectrophotometry with aluminum chloride reagent (total flavonoids in terms of rutoside), gravimetry (total extractives, extracted by water), permanganatometric titration (total tannins in terms of tannin). Rutoside, tannin, gallic acid and salicylic acid were identified in Filipendula ulmaria herb, flowers and leafs by TLC. Also we analyzed content of substances extracted by water, flavonoids and tannins. Total extractives, extracted by water in F. ulmaria herb is 13.12±0.10%, in leafs – 13.98±0.37%, in flowers – 18.09±0.17%. Total tannins in F. ulmaria herb is 11.87±0.47%, in leafs – 12.06±0.18%, in flowers – 12.26±0.29%. Total flavonoids in F. ulmaria herb 4.34±0.17%, in leafs – 6.98±0.23%, in flowers – 11.75±0.57%. The obtained data will be used for development of a pharmacopoeial monograph project "Filipendula ulmaria (L.) Maxim., herba" for inclusion in the State Pharmacopoeia of the Russian Federation.

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