Preparation and Blood Compatibility of Epoxidized Castor Oil-Based Polyurethane/Chitosan Biomedical Materials

2009 ◽  
Vol 79-82 ◽  
pp. 219-222 ◽  
Author(s):  
Guo Ming Li ◽  
Ya Xin He ◽  
Xing Liu ◽  
Juan Su ◽  
Gao Fei Qu
Keyword(s):  
Acetic Acid ◽  
Castor Oil ◽  
Blood Clotting ◽  
Blood Compatibility ◽  
Raw Materials ◽  
Optical Polarization ◽  
Isophorone Diisocyanate ◽  
Biomedical Materials ◽  
Recalcification Time ◽  
Epoxidized Castor Oil

Epoxidized castor oil-based polyurethane were synthesized with epoxidized castor oil (ECO) and isophorone diisocyanate (IPDI) as the main raw materials. Epoxidized castor oil-based polyurethane (ECOPU) films were impregnated in different concentrations of chitosan (CS) solution containing acetic acid to prepare CS/ECOPU composite film. The structure and morphologies of the film have been characterized by means of mass change test, infrared spectroscopy, and optical polarization microscope. The recalcification time and dynamic blood-clotting tests were used to characterize the blood compatibility of CS/ECOPU composition film. The result showed that CS has been grafted onto the surface of ECOPU film. The material had good blood compatibility, and can be used as biomedical materials.

scholarly journals Poly(Vinylamine) Derived N-Doped C-Dots with Antimicrobial and Antibiofilm Activities

2021 ◽  
Vol 7 (2) ◽  
pp. 40
Author(s):  
Semiha Duygu Sutekin ◽  
Mehtap Sahiner ◽  
Selin Sagbas Suner ◽  
Sahin Demirci ◽  
Olgun Güven ◽  
...  
Keyword(s):  
Blood Clotting ◽  
Minimum Bactericidal Concentration ◽  
Blood Compatibility ◽  
Weight Ratio ◽  
Gram Negative Bacteria ◽  
Biofilm Inhibition ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Doped Carbon Dots ◽  
Nitrogen Doped Carbon

Nitrogen-doped carbon dots (N-doped C-dots) was synthesized by using poly(vinyl amine) (PVAm) as a nitrogen source and citric acid (CA) as a carbon source via the hydrothermal method. Various weight ratios of CA and PVAm (CA:PVAm) were used to synthesize N-doped C-dots. The N-doped C-dots revealed emission at 440 nm with excitation at 360 nm and were found to increase the fluorescence intensity with an increase in the amount of PVAm. The blood compatibility studies revealed no significant hemolysis for N-doped C-dots that were prepared at different ratios of CA:PVAm for up to 500 μg/mL concentration with the hemolysis ratio of 1.96% and the minimum blood clotting index of 88.9%. N-doped C-dots were found to be more effective against Gram-positive bacteria than Gram-negative bacteria, with the highest potency on Bacillus subtilis (B. subtilis). The increase in the weight ratio of PVAm in feed during C-dots preparation from 1 to 3 leads to a decrease of the minimum bactericidal concentration (MBC) value from 6.25 to 0.75 mg/mL for B. subtilis. Antibiofilm ability of N-doped C-dots prepared by 1:3 ratio of CA:PVAm was found to reduce %biofilm inhibition and eradication- by more than half, at 0.78 mg/mL for E. coli and B. subtilis generated biofilms and almost destroyed at 25 mg/mL concentrations.

Synthesis, Characterization and Application of Multi-Generations Hyperbranched Polyurethane Based on Isophorone Diisocyanate

2012 ◽  
Vol 554-556 ◽  
pp. 126-129 ◽  
Author(s):  
Shun Yin ◽  
Ning Sun ◽  
Chun Yun Feng ◽  
Zhi Mou Wu ◽  
Zhao Hua Xu ◽  
...  
Keyword(s):  
Differential Scanning Calorimetry ◽  
Raw Materials ◽  
Degradation Mechanism ◽  
Resonance Spectroscopy ◽  
Gravimetric Analysis ◽  
Thermal Gravimetric ◽  
Isophorone Diisocyanate ◽  
Scanning Calorimetry ◽  
Degradation Temperature ◽  
Hyperbranched Polyurethane

A series of different generation hyperbranched polyurethane(HBPU) was synthesized based on the raw materials of isophorone diisocyanate(IPDI) and diethanolamine(DEOA). Their structure, thermal degradation mechanism and glass transition temperature(Tg) were characterized by fourier transform infrared spectroscopy(FTIR), nuclear magnetic resonance spectroscopy(NMR), thermal gravimetric analysis(TGA) and differential scanning calorimetry(DSC). The results showed that: the yield of each generation HBPU was up to 90%, different generation HBPU had almost the same initial degradation temperature(about at 200°C) and they all had two decomposition platforms; with the increase of generation, Tg increased from 107.2°C to 132.1°C. The gloss and hardness of the HBPU coatings were significantly improved.

scholarly journals Synthesis and Biological Application of Polylactic Acid

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5023
Author(s):  
Ge Li ◽  
Menghui Zhao ◽  
Fei Xu ◽  
Bo Yang ◽  
Xiangyu Li ◽  
...  
Keyword(s):  
Physical Properties ◽  
Polylactic Acid ◽  
Biomedical Applications ◽  
Raw Materials ◽  
Raw Material ◽  
Biomedical Materials ◽  
Biomedical Material ◽  
Sugar Fermentation ◽  
Low Toxicity ◽  
Good Biocompatibility

Over the past few decades, with the development of science and technology, the field of biomedicine has rapidly developed, especially with respect to biomedical materials. Low toxicity and good biocompatibility have always been key targets in the development and application of biomedical materials. As a degradable and environmentally friendly polymer, polylactic acid, also known as polylactide, is favored by researchers and has been used as a commercial material in various studies. Lactic acid, as a synthetic raw material of polylactic acid, can only be obtained by sugar fermentation. Good biocompatibility and biodegradability have led it to be approved by the U.S. Food and Drug Administration (FDA) as a biomedical material. Polylactic acid has good physical properties, and its modification can optimize its properties to a certain extent. Polylactic acid blocks and blends play significant roles in drug delivery, implants, and tissue engineering to great effect. This article describes the synthesis of polylactic acid (PLA) and its raw materials, physical properties, degradation, modification, and applications in the field of biomedicine. It aims to contribute to the important knowledge and development of PLA in biomedical applications.

scholarly journals Synthesis of Pectiniform Polyurethane-Modified Polycarboxylate and Its Preliminary Application in Ultrahigh-Performance Concrete

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Shuncheng Xiang ◽  
Yingli Gao
Keyword(s):  
Silica Fume ◽  
Negative Impact ◽  
Raw Materials ◽  
Synthesis Method ◽  
Autogenous Shrinkage ◽  
Drying Shrinkage ◽  
Isophorone Diisocyanate ◽  
Initiation System ◽  
Dry Shrinkage ◽  
Preliminary Application

In this paper, modified polyurethane prepolymer was synthesized by the segmental synthesis method using isophorone diisocyanate (IPDI), hydroxyl-terminated silicone, and polyether glycol dimethylolpropionic acid as raw materials. After that, pectiniform polycarboxylate, of which side chains were in roughly the same polymerization degree and main chains were in different lengths, was synthesized at normal temperature in the complex initiation system of H2O2, APS, sodium bisulfite, and Vc. Then, compared with commercial Sika polycarboxylate, their applications in ultrahigh-performance concrete (HUPC), including flowability, strength, drying shrinkage, and autogenous shrinkage, were investigated. The results showed that, due to the molecular structure of polyorganosiloxane, the synthesized polycarboxylate could be better dispersed. Dosage of silica fume could effectively improve the compressive strength of UHPC, while slag had a certain negative impact on its strength. Incorporation of slag and silica fume could effectively reduce the dry shrinkage of UHPC.

Characterization of Medium Density Particleborads Using Agricultural Residues

2015 ◽  
Vol 1088 ◽  
pp. 656-659
Author(s):  
Ivaldo D. Valarelli ◽  
Rosane A.G. Battistelle ◽  
Barbara Stolte Bezerra ◽  
Luiz A. Melgaço N. Branco ◽  
Eduardo Chahud ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Castor Oil ◽  
Mechanical Characteristics ◽  
Mechanical Characterization ◽  
Raw Materials ◽  
Construction Materials ◽  
Agricultural Residues ◽  
Medium Density ◽  
Polyurethane Resin

In recent years the production of products derived from wood and bamboo are increasing, due to the search for a more rational exploitation of these raw materials. Amongst these products, the particleboards production combine sustainability and rationality in the use of these materials. In this context, this work has the objective to study the application of alternative raw materials in the manufacture of Medium Density Particleboards (MDP), using residues from industrial processimg of coffee and bamboo. MDP had been produced with particles of giganteus bamboo of the Dendrocalamus species and particle of coffee rind in the intermediate layer of the particleboard, bonded with polyurethane resin based on castor oil. The physical and mechanical characterization was carried out accordingly to NBR 14810-3 (2006). The physical properties evaluated were: of water absorption for 2h and 24h; thickness swallowing for 2h and 24h; density, humidity content. The mechanical properties evaluated were: Tensile strength, static bending (MOR and MOE). The results were compared with NBR 14810-2 (2006) and also with the ANSI A208-1 (1993). The physical performance of these particleboards was below the values recommend by the Brazilian norm. Also the mechanical characteristics are not improve, demonstrating that the inclusion of coffee rind did not benefit the physical characteristics and nor the mechanical ones. However it can be used as construction materials for partitions and ceiling panels.

scholarly journals Analgesic and Antidiarrheal Activities of Leaf of Podocarpus neriifolius D. Don

2016 ◽  
Vol 19 (2) ◽  
pp. 215-218
Author(s):  
Md Rahatullah Razan ◽  
Muhammed Mahfuzur Rahman ◽  
Faiza Tahia ◽  
Md Khalid Hossain ◽  
Mohammad A Rashid
Keyword(s):  
Body Weight ◽  
Acetic Acid ◽  
Analgesic Activity ◽  
Castor Oil ◽  
Methanol Extract ◽  
Methanolic Extract ◽  
Pharmaceutical Journal ◽  
Activity Assay ◽  
Swiss Albino Mice

The methanol extract of leaf of Podocarpus neriifolius D. Don exhibited in vivo peripheral analgesic and antidiarrheal activities in Swiss Albino mice. In the peripheral analgesic activity assay, the methanolic extract showed 50.00 ± 8.57% and 70.25 ± 1.18% inhibition of acetic acid-induced writhing at 200 and 400 mg/kg body weight, respectively. In addition, the extract also revealed a dose dependant inhibition of castor oil- induced diarrhea with 43.77 ± 3.13% and 56.23 ± 6.49% inhibition of feces at 200 and 400 mg/kg body weight, respectivelyBangladesh Pharmaceutical Journal 19(2): 215-218, 2016

Preparation of functionalized castor oil derivatives with tunable physical properties using heterogeneous acid and base catalysts

RSC Advances ◽  
2015 ◽  
Vol 5 (62) ◽  
pp. 50289-50297 ◽  
Author(s):  
Sivashunmugam Sankaranarayanan ◽  
Kannan Srinivasan
Keyword(s):  
Physical Properties ◽  
Castor Oil ◽  
Ring Opening ◽  
Heterogeneous Catalysts ◽  
Base Catalysts ◽  
Acid And Base ◽  
Oil Derivatives ◽  
Epoxidized Castor Oil

Functionalized castor oil derivatives are achieved from epoxidized castor oil through ring opening and transesterification reactions using heterogeneous catalysts.

Temperature Dependence of LiMn2O4 Prepared by a Solution Combustion Synthesis in the System of Acetate Salts and Acetic Acid

2012 ◽  
Vol 485 ◽  
pp. 465-468
Author(s):  
Li Li Zhang ◽  
Gui Yang Liu ◽  
Jun Ming Guo ◽  
Bao Sen Wang ◽  
Ying He
Keyword(s):  
Acetic Acid ◽  
Combustion Synthesis ◽  
Raw Materials ◽  
Synthesis Method ◽  
Solution Combustion Synthesis ◽  
Electrochemical Performances ◽  
Metal Foil ◽  
X Ray Diffraction ◽  
Solution Combustion ◽  
Acid Ratio

Spinel LiMn2O4 have been prepared by the solution combustion synthesis method using acetate salts as raw materials and acetic acid as fuel. The phase compositions of the as-prepared products were determined by X-ray diffraction (XRD). The electrochemical performance of the products was tested by using a coin-type half battery versus lithium metal foil as anode material. XRD results suggested that the purities of the products prepared at 500oC are higher than these of the products prepared at 600oC. For the products prepared at 500oC, the purities of the products increase with increasing acetic acid ratios. But for the products prepared at 600oC, the purities of the products decrease with increasing acetic acid ratios. The performance tests indicated that the electrochemical performances of the products prepared at 500oC are better than these of the products prepared at 600oC. The product prepared at 500oC with the acetic acid ratio of 1.0 gets the best performance. The initial capacity of it reaches to 124.8mAh/g at the current density of 75mA/g, and after 50 cycles, the capacity retention is 93.7%.

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