Ozone-Induced Immobilization of Chitosan and Heparin on Polyethylene Terephthalate Films to Improve Antithrombogenic Properties

2007 ◽  
Vol 342-343 ◽  
pp. 809-812 ◽  
Author(s):  
Jian Xin Li ◽  
Jin Wang ◽  
Peng Li ◽  
Ya Jun Weng ◽  
Ling Ren ◽  
...  
Keyword(s):  
Contact Angle ◽  
Polyethylene Terephthalate ◽  
Photoelectron Spectroscopy ◽  
Platelet Rich Plasma ◽  
Static Contact Angle ◽  
Adhesion Test ◽  
Artificial Blood ◽  
X Ray ◽  
Static Contact ◽  
Pet Films

of artificial blood catheters. This paper describes the immobilization of chitosan and heparin molecules on polyethylene terephthalate (PET) films by ozonization. The concentration of peroxide groups (-OOH) was 1.72 × 10-7 mol/cm2 on the PET surface oxidized by ozonization. The results of X-ray photoelectron spectroscopy (XPS) indicate that chains of chitosan and heparin were successfully immobilized on the PET films. The static contact angle(STA) of water decreases from 83.5° to 68.3° by immobilization of chitosan and heparin, which means that the hydrophilic properties of the modified PET is improved. The antithrombogenic property of PET surface was evaluated by a platelet-rich plasma (PRP) adhesion test. The results indicate that the number of platelet adhered on the modified-PET surface incubated with PRP for 240 min decreased significantly and platelets did not aggregate and distort.

scholarly journals A Versatile Star PEG Grafting Method for the Generation of Nonfouling and Nonthrombogenic Surfaces

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Pradeep Kumar Thalla ◽  
Angel Contreras-García ◽  
Hicham Fadlallah ◽  
Jérémie Barrette ◽  
Gregory De Crescenzo ◽  
...  
Keyword(s):  
Contact Angle ◽  
Photoelectron Spectroscopy ◽  
Primary Amine ◽  
Quartz Crystal ◽  
Platelet Adhesion ◽  
Covalent Binding ◽  
Strong Reduction ◽  
X Ray ◽  
Static Contact ◽  
Biomaterial Surfaces

Polyethylene glycol (PEG) grafting has a great potential to create nonfouling and nonthrombogenic surfaces, but present techniques lack versatility and stability. The present work aimed to develop a versatile PEG grafting method applicable to most biomaterial surfaces, by taking advantage of novel primary amine-rich plasma-polymerized coatings. Star-shaped PEG covalent binding was studied using static contact angle, X-ray photoelectron spectroscopy (XPS), and quartz crystal microbalance with dissipation monitoring (QCM-D). Fluorescence and QCM-D both confirmed strong reduction of protein adsorption when compared to plasma-polymerized coatings and pristine poly(ethyleneterephthalate) (PET). Moreover, almost no platelet adhesion was observed after 15 min perfusion in whole blood. Altogether, our results suggest that primary amine-rich plasma-polymerized coatings offer a promising stable and versatile method for PEG grafting in order to create nonfouling and nonthrombogenic surfaces and micropatterns.

Structure and Properties of Regenerated Cellulose Film with Fluorocarbon Coating

2011 ◽  
Vol 84-85 ◽  
pp. 47-52
Author(s):  
Yu Hui Zhang ◽  
Quan Ji ◽  
Hong Jin Qi ◽  
Xi Quan Sun
Keyword(s):  
Contact Angle ◽  
Photoelectron Spectroscopy ◽  
Oxygen Permeability ◽  
Rf Magnetron Sputtering ◽  
Substrate Material ◽  
Static Contact Angle ◽  
Regenerated Cellulose ◽  
Cellulose Film ◽  
Regenerated Cellulose Film ◽  
Static Contact

Fluorocarbon coatings were deposited on the surface of regenerated cellulose films by RF magnetron sputtering, using polytetrafluoroethylene targets. Argon was used as the working gas. The coatings were characterized by X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, atomic force microscopy, and static contact angle and oxygen permeability measurements. It was found that the coatings were made up of the four components -CF3, -CF2-, -CF- and -C-. The [F]/[C] ratio varied with sputtering conditions. The static contact angle of the coatings was greater than 90° at lower power and higher pressure, and the substrate material was transformed from hydrophilic to hydrophobic character. The fluorocarbon coatings were porous and did not influence the oxygen permeability of the cellulose film substrates.

Grafting Biomimetic Phospholipid Zwitterionic Brushes onto Polycarbonateurethane for Improving Hemocompatibility

2011 ◽  
Vol 306-307 ◽  
pp. 3-6
Author(s):  
Hai Yang Zhao ◽  
Ya Kai Feng ◽  
Da Zhi Yang ◽  
Jin Tang Guo ◽  
Qing Liang Chen ◽  
...  
Keyword(s):  
Contact Angle ◽  
Fourier Transform ◽  
Water Contact Angle ◽  
Photoelectron Spectroscopy ◽  
Potential Application ◽  
Platelet Adhesion ◽  
Material Surface ◽  
Adhesion Test ◽  
Water Contact ◽  
X Ray

In order to improve the hemocompatibility of polycarbonateurethane (PCU), the biomimetic phosphorylcholine (PC) group was introduced onto material surface. Brush structure having PC groups was formed by ultraviolet (UV) initiated polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) to improve the hydrophilicity and hemocompatibility of PCU surfaces. Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electrical microscopy (SEM) and water contact angle were used to characterize the chemical and physical properties of the modified PCU surfaces. Compared with original PCU, the PC-grafted PCU surfaces showed significantly high hydrophilicity as indicating by low water contact angle. The hemocompatibility of the PC-grafted PCU surfaces was evaluated by platelet adhesion test. The PCU surfaces modified with phosphorylcholine zwitterionic brushes showed effective resistance to platelet adhesion and high hemocompatibility. These PC-grafted PCU materials will have potential application as blood-contacting materials or devices due to their good mechanical and hemocompatible properties.

The Effects of Contents of Oxygen in Argon-Oxygen Mixed Gas on Polyethylene Terephthalate (PET) Films by CCP Discharge

2013 ◽  
Vol 651 ◽  
pp. 257-262
Author(s):  
Yan Feng Xie ◽  
Hong Ying Zhou ◽  
Di Zhang ◽  
Han Wen Zhang ◽  
Yun Cheng Shi ◽  
...  
Keyword(s):  
Contact Angle ◽  
Chemical Composition ◽  
Polyethylene Terephthalate ◽  
Photoelectron Spectroscopy ◽  
Surface Composition ◽  
Optical Emission ◽  
Active Species ◽  
Mixed Gas ◽  
Adhesion Properties ◽  
Pet Films

In the present work, Polyethylene terephthalate (PET) films have been exposed to capacitive coupled plasma (CCP) to improve their surface properties for fabricated devices. Contact angle measurements and atomic force microscopy (AFM) showed an increase in surface roughness resulting in the decrease of contact angle. Surface composition and morphology of the films were analyzed by X-ray photoelectron spectroscopy (XPS) and AFM. It was found that the plasma treatment modified the surfaces both in chemical composition and morphology. Change of chemical composition made the polymer surfaces to be highly hydrophilic, which mainly depends on the increase in oxygen-containing groups. And the results of optical emission spectroscopy (OES) proved that appropriate content of oxygen in mixture gas can create the greatest number of active species to form O*-C causes groups on surface which can easily form C-O-metal bonds, lead to improve adhesion properties.

scholarly journals Anti-Icing Performance of a Coating Based on Nano/Microsilica Particle-Filled Amino-Terminated PDMS-Modified Epoxy

Coatings ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 771 ◽  
Author(s):  
Qiang Xie ◽  
Tianhui Hao ◽  
Jifeng Zhang ◽  
Chao Wang ◽  
Rongkui Zhang ◽  
...  
Keyword(s):  
Contact Angle ◽  
Adhesion Strength ◽  
Photoelectron Spectroscopy ◽  
Contact Angle Hysteresis ◽  
Ice Formation ◽  
Adhesion Test ◽  
X Ray ◽  
Modified Epoxy ◽  
Scanning Electron ◽  
Ice Adhesion

Coatings with anti-icing performance possess hydrophobicity and low ice adhesion strength, which delay ice formation and make ice removal easier. In this paper, the anti-icing performance of nano/microsilica particle-filled amino-terminated PDMS (A-PDMS)-modified epoxy coatings was investigated. In the process, the influence of the addition of A-PDMS on the hydrophobicity and ice adhesion strength was investigated. Furthermore, the influences of various weight ratios of nanosilica/microsilica (Rn/m) on the hydrophobicity and ice adhesion strength of the coating were investigated. Hydrophobicity was evaluated by contact angle (CA) and contact angle hysteresis (CAH) tests. Ice adhesion strength was measured by a centrifugal adhesion test. The addition of A-PDMS markedly increased hydrophobicity and decreased ice adhesion. The size combination of particles obviously affects hydrophobicity but has little effect on ice adhesion. Finally, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) were used to reveal the anti-icing mechanism of the coatings.

Hydrophobic Modification on Surface of Silicone Rubber by Tetrafluoromethane Radio Frequency Inductively Coupled Plasma

2014 ◽  
Vol 1003 ◽  
pp. 69-73
Author(s):  
Song Hua Gao ◽  
Li Hua Gao
Keyword(s):  
Contact Angle ◽  
Radio Frequency ◽  
Silicone Rubber ◽  
Photoelectron Spectroscopy ◽  
Inductively Coupled Plasma ◽  
Hydrophobic Modification ◽  
Hydrophobic Property ◽  
X Ray ◽  
Inductively Coupled ◽  
Static Contact

Hydrophobic modification on surface of silicone rubber by CF4 radio frequency inductively coupled plasma is discussed. Static contact angle and X-ray photoelectron spectroscopy were used in characterizing the hydrophobic property and chemical composition of the modified silicone rubber. The results show that the improvement of surface hydrophobic property on modified silicone rubber is put down to the introduction of fluorocarbon functional groups (C-CFn, n=1, 2,3) and fluosilicic structures (Si-F and Si-F2) during the treatment.

Sign in / Sign up

Export Citation Format

Share Document