Preparation, Characterization and Applications of Enzyme-Free Glucose Sensors

2017 ◽  
Vol 730 ◽  
pp. 172-176
Author(s):  
Jing Chao Hong ◽  
Gu Qin
Keyword(s):  
Glucose Sensor ◽  
Electrochemical Biosensor ◽  
Glucose Sensors ◽  
Fourth Generation ◽  
Preparation Methods ◽  
Great Progress ◽  
Free Glucose ◽  
New Material ◽  
Application Fields

With the continuous development of science and technology, the function of the electrochemical biosensor is becoming more and more diversified. The fourth generation of enzyme-free glucose sensor because of its particular advantages has become one of research focuses in glucose sensor now. For all sorts of optimization also are not enzyme glucose as the new material was born has made great progress. Enzyme-free glucose sensors are becoming more and more an integral part of electrochemical research. This article summarizes the characteristics of all kinds of conventional materials of enzyme-free glucose sensor, the domestic and foreign general preparation methods of enzyme-free glucose sensors, the specific characterization of the electrode, its application fields, and prospects for future development.

Affinity Viscosimetry Sensor for Enzyme Free Detection of Glucose in a Micro-Bioreaction Chamber

2016 ◽  
Vol 879 ◽  
pp. 1135-1140
Author(s):  
Thilo Liebscher ◽  
Franziska Glös ◽  
Andrea Böhme ◽  
M. Birkholz ◽  
M. di Vona ◽  
...  
Keyword(s):  
Glucose Concentration ◽  
Glucose Sensor ◽  
Time Measurement ◽  
Glucose Sensors ◽  
Cell Cultivation ◽  
New Approach ◽  
Microelectromechanical System ◽  
Long Time ◽  
Free Glucose

With the growing demand of miniaturization of cell cultivation a new approach towards measuring and sensing bio-analytes needs to be made due to the problem of small volumes (less than 150μl) containing small amounts of analytes. Most of the available glucose sensors monitor the glucose concentration with the help of enzymes, which become very inaccurate in terms of long time measurement and uses (i.e. consumes) glucose during the measurement becoming not available anymore for the cells. Therefore, we focused on applying an enzyme-free glucose sensor based on a microelectromechanical system (MEMS).

scholarly journals Non-enzymatic glucose sensor with electrodeposited silver/carbon nanotubes composite electrode

2019 ◽  
Vol 39 (6) ◽  
Author(s):  
Syeda Ammara Shabbir ◽  
Sana Tariq ◽  
M. Gul Bahar Ashiq ◽  
Waqar A. Khan
Keyword(s):  
Carbon Nanotubes ◽  
Tin Oxide ◽  
Composite Electrode ◽  
Reduction Potential ◽  
Glucose Sensor ◽  
Electrochemical Process ◽  
Glucose Sensors ◽  
Functionalized Carbon Nanotubes ◽  
Good Electrocatalytic Activity ◽  
Free Glucose

Abstract Diabetes mellitus is a debilitating disease that affects each and every organ of human body. Hence it is important to continuously monitor the glucose level throughout the day and night. Glucose sensors are in great demand due to a rapid increase in diabetic community. A strategy has been implemented here to fabricate silver nanoparticles (AgNPs) with the support of functionalized carbon nanotubes (f-CNTs). Silver/carbon nanotubes (Ag/CNTs) nanocomposite electrode have been prepared by electrochemical process on Fluorine doped tin oxide (FTO) glass, by varying silver (Ag) concentrations for non-enzymatic glucose sensor. The variable Ag concentration in the morphology of Ag/CNTs nanocomposite has influenced the electrical conductivity, oxidation and reduction potential and electrochemical activity of glucose. Highest current density and good electrocatalytic activity for electrodes are obtained at 70 mM concentration of silver in Ag/CNTs composite. The present study indicates that the Ag/CNTs electrode is a possible substitute of the expensive glassy carbon electrode for enzyme-free glucose sensors.

Characterization of a monolayer graphitic structure

1994 ◽  
Vol 52 ◽  
pp. 760-761
Author(s):  
X. Lin ◽  
X. K. Wang ◽  
V. P. Dravid ◽  
J. B. Ketterson ◽  
R. P. H. Chang
Keyword(s):  
Three Dimensional ◽  
Single Layer ◽  
Synthesis Process ◽  
Graphitic Structure ◽  
Positive Gaussian Curvature ◽  
Graphitic Sheet ◽  
Structural And Electronic Properties ◽  
New Material ◽  
Hexagonal Network

For small curvatures of a graphitic sheet, carbon atoms can maintain their preferred sp2 bonding while allowing the sheet to have various three-dimensional geometries, which may have exotic structural and electronic properties. In addition the fivefold rings will lead to a positive Gaussian curvature in the hexagonal network, and the sevenfold rings cause a negative one. By combining these sevenfold and fivefold rings with sixfold rings, it is possible to construct complicated carbon sp2 networks. Because it is much easier to introduce pentagons and heptagons into the single-layer hexagonal network than into the multilayer network, the complicated morphologies would be more common in the single-layer graphite structures. In this contribution, we report the observation and characterization of a new material of monolayer graphitic structure by electron diffraction, HREM, EELS.The synthesis process used in this study is reported early. We utilized a composite anode of graphite and copper for arc evaporation in helium.

Low-voltage field-emission SEM of polymeric membranes for glucose biosensors

1990 ◽  
Vol 48 (3) ◽  
pp. 860-861
Author(s):  
Lorna K. Mayo ◽  
Kenneth C. Moore ◽  
Mark A. Arnold
Keyword(s):  
Glucose Sensor ◽  
Low Voltage ◽  
Glucose Sensors ◽  
Polymeric Membranes ◽  
Artificial Endocrine Pancreas ◽  
Self Monitoring ◽  
Conducting Materials ◽  
Insulin Dependent ◽  
Living Tissues ◽  
Voltage Scanning

An implantable artificial endocrine pancreas consisting of a glucose sensor and a closed-loop insulin delivery system could potentially replace the need for glucose self-monitoring and regulation among insulin dependent diabetics. Achieving such a break through largely depends on the development of an appropriate, biocompatible membrane for the sensor. Biocompatibility is crucial since changes in the glucose sensors membrane resulting from attack by orinter action with living tissues can interfere with sensor reliability and accuracy. If such interactions can be understood, however, compensations can be made for their effects. Current polymer technology offers several possible membranes that meet the unique chemical dynamics required of a glucose sensor. Two of the most promising polymer membranes are polytetrafluoroethylene (PTFE) and silicone (Si). Low-voltage scanning electron microscopy, which is an excellent technique for characterizing a variety of polymeric and non-conducting materials, 27 was applied to the examination of experimental sensor membranes.

Physical - Chemical Issues of Cephalosporin Intercalated Nanoparticles for Life - Threatening Infections Treatment

2001 ◽  
Vol 71 (3) ◽  
pp. 342-349
Author(s):  
Lucian Eva ◽  
Letitia Doina Duceac ◽  
Liviu Stafie ◽  
Constantin Marcu ◽  
Geta Mitrea ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Advanced Characterization ◽  
Generation Cephalosporin ◽  
Fourth Generation ◽  
Exchange Method ◽  
Physico Chemical ◽  
Life Threatening ◽  
Double Hydroxide ◽  
Double Hydroxides

The fourth generation cephalosporin antibacterial agent, cefepime, was loaded into layered double hydroxides for enhancing antibiotic efficiency, reducing side effects, as well as achieving the sustained release property. The intercalation of antibiotic into the inter-gallery of ZnAl-layered double hydroxide (LDH) was carried out using ion exchange method, by this constituting a nano-sized organic-inorganic hybrid material for a controlled release novel formulation. Although cefepime is a broad spectrum antibiotic, it has various adverse effects and a significant degradation rate. Thus, the preparation and physico-chemical characterization of nanomaterials able to intercalate this drug is an important study for medical and pharmaceutical field. The antibiotic inclusion into LDHs nanostructure was confirmed by advanced characterization techniques and the release profile of cefepime was analysed with the respect to pH of the simulated media.

scholarly journals Design and Characterization of Gypsum Mortars Dosed with Polyurethane Foam Waste PFW

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1497 ◽  
Author(s):  
Isabel Santamaría Vicario ◽  
Lourdes Alameda Cuenca-Romero ◽  
Sara Gutiérrez González ◽  
Verónica Calderón Carpintero ◽  
Ángel Rodríguez Saiz
Keyword(s):  
Natural Resources ◽  
Construction Industry ◽  
Polyurethane Foam ◽  
Industrial Waste ◽  
Vapour Permeability ◽  
Polyurethane Waste ◽  
New Material ◽  
Technical Specifications ◽  
Mechanical Strengths

The properties and the behaviour of plaster mortars designed with Polyurethane Foam Waste (PFW) are studied in this investigation. A characterization of the mixtures is completed, in accordance with the technical specifications of European Norms. The incorporation of polyurethane waste foam can yield porous and lighter mortars, with better resistance to water-vapour permeability, although with weaker mechanical strength and higher levels of absorbency. Nevertheless, suitable mechanical strengths were achieved, resulting in a new material that is compliant with the requirements of the construction industry. The use of PFW in the the manufacture of gypsum mortars for construction reduces the consumption of natural resources and, at the same time, recovers an industrial waste that is otherwise difficult to recycle.

scholarly journals Waste eggshell membrane-templated synthesis of functional Cu2+–Cu+/biochar for an ultrasensitive electrochemical enzyme-free glucose sensor

RSC Advances ◽  
2021 ◽  
Vol 11 (31) ◽  
pp. 18994-18999
Author(s):  
Linzhi Li ◽  
Tianzeng Huang ◽  
Saijun He ◽  
Xing Liu ◽  
Qi Chen ◽  
...  
Keyword(s):  
Glucose Sensor ◽  
Glucose Sensing ◽  
Fabrication Process ◽  
Eggshell Membrane ◽  
Templated Synthesis ◽  
Free Glucose

The fabrication process of the nonenzyme glucose sensing based Cu2+–Cu+/biochar.

scholarly journals Facile Synthesis and Characterization of Palm CNF-ZnO Nanocomposites with Antibacterial and Reinforcing Properties

2021 ◽  
Vol 22 (11) ◽  
pp. 5781
Author(s):  
Janarthanan Supramaniam ◽  
Darren Yi Sern Low ◽  
See Kiat Wong ◽  
Loh Teng Hern Tan ◽  
Bey Fen Leo ◽  
...  
Keyword(s):  
Plant Biomass ◽  
Cellulose Nanofibers ◽  
High Strength ◽  
Salmonella Typhi ◽  
Particle Sizes ◽  
Mechanical Reinforcement ◽  
Uniform Size ◽  
Preparation Methods ◽  
Potential Applications

Cellulose nanofibers (CNF) isolated from plant biomass have attracted considerable interests in polymer engineering. The limitations associated with CNF-based nanocomposites are often linked to the time-consuming preparation methods and lack of desired surface functionalities. Herein, we demonstrate the feasibility of preparing a multifunctional CNF-zinc oxide (CNF-ZnO) nanocomposite with dual antibacterial and reinforcing properties via a facile and efficient ultrasound route. We characterized and examined the antibacterial and mechanical reinforcement performances of our ultrasonically induced nanocomposite. Based on our electron microscopy analyses, the ZnO deposited onto the nanofibrous network had a flake-like morphology with particle sizes ranging between 21 to 34 nm. pH levels between 8–10 led to the formation of ultrafine ZnO particles with a uniform size distribution. The resultant CNF-ZnO composite showed improved thermal stability compared to pure CNF. The composite showed potent inhibitory activities against Gram-positive (methicillin-resistant Staphylococcus aureus (MRSA)) and Gram-negative Salmonella typhi (S. typhi) bacteria. A CNF-ZnO-reinforced natural rubber (NR/CNF-ZnO) composite film, which was produced via latex mixing and casting methods, exhibited up to 42% improvement in tensile strength compared with the neat NR. The findings of this study suggest that ultrasonically-synthesized palm CNF-ZnO nanocomposites could find potential applications in the biomedical field and in the development of high strength rubber composites.

Mixed Ni–Cu-oxide nanowire array on conductive substrate and its application as enzyme-free glucose sensor

2012 ◽  
Vol 4 (12) ◽  
pp. 4003 ◽  
Author(s):  
Ruimin Ding ◽  
Jinping Liu ◽  
Jian Jiang ◽  
JianHui Zhu ◽  
Xintang Huang
Keyword(s):  
Glucose Sensor ◽  
Nanowire Array ◽  
Conductive Substrate ◽  
Free Glucose

Highly Selective Separation and Enrichment of Phosphopeptides by Uranyl-Salophen Immobilized Silica Gel Material

2015 ◽  
Vol 1095 ◽  
pp. 341-344 ◽  
Author(s):  
Can Hui Xu ◽  
Guang Liang Zhang ◽  
Xin Zhou ◽  
Xi Lin Xiao ◽  
Chang Ming Nie ◽  
...  
Keyword(s):  
Silica Gel ◽  
Metal Ion ◽  
High Selectivity ◽  
Separation Efficiency ◽  
Solid Phase ◽  
Tetradentate Ligand ◽  
Peptide Mixtures ◽  
New Material ◽  
Solid Phase Material

The characterization of phosphoproteins requires highly specific methods for the separation and enrichment of phosphopeptides. Here we report a novel metal ion-immobilized solid phase material for the separation and enrichment of phosphopeptides. The material is uranyl-salophen-silica gel (USSG) particles in which salophen is a tetradentate ligand of uranyl ion. In USSG salophen is connected on the surface of silica gel and uranyl is bound on the surface through its coordination with salophen. Phosphopeptides can be selectively retained by USSG because uranyl-salophen can bind phosphate moiety with strong affinity and high selectivity. The new material USSG has been successfully used for the separation of phosphopeptides from peptide mixtures with the separation efficiency of 97.0% to 97.4%.

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