Xanthan Gum-Incorporated Natural Rubber Film Casted with Solvent Evaporation

2020 ◽  
Vol 859 ◽  
pp. 68-73
Author(s):  
Napaphol Puyathorn ◽  
Thawatchai Phaechamud
Keyword(s):  
Natural Rubber ◽  
Water Sorption ◽  
Wound Dressing ◽  
Xanthan Gum ◽  
Composite Films ◽  
Area Under The Curve ◽  
High Water ◽  
Solvent Casting ◽  
Casting Method ◽  
Rubber Film

Xanthan gum (X)-incorporated natural rubber (NR) cast films were fabricated from blocked NR by solvent casting method using dichloromethane as the solvent. The rather smooth films were obtained. X markedly promoted both of water sorption and erosion in phosphate buffer pH 7.4 of these composite films. With increasing X amount also significantly enhanced the film tensile strength, Young’s modulus and area under the curve while did not affect contact angle of water/formamide and surface free energy. 30%X-loaded NR films exhibited the highest durability with apparently high water sorption and erosion for further using such as wound dressing.

scholarly journals FORMULATION AND EVALUATION OF FAST DISSOLVING FILMS OF ELETRIPTAN HYDROBROMIDE

2017 ◽  
Vol 9 (2) ◽  
pp. 59
Author(s):  
K. Pallavi ◽  
T. Pallavi
Keyword(s):  
Drug Release ◽  
Xanthan Gum ◽  
Guar Gum ◽  
Methyl Cellulose ◽  
Synthetic Polymers ◽  
Locust Bean Gum ◽  
Solvent Casting ◽  
Casting Method ◽  
Disintegration Time ◽  
Locust Bean

Objective: The main aim of the present research was to develop an oral fast dissolving polymeric film (FDF) with good mechanical properties, faster disintegration and dissolution when placed on the tongue.Methods: Eletriptan hydrobromide is prescribed for the treatment of mild to a moderate migraine. The polymers selected for preparing films were Pullulan, Maltodextrin (MDX), Acacia, Sodium alginate (SA), Locust bean gum (LBG), Guar gum (GG), Xanthan gum (XG), Polyvinyl alcohol (PVA), Polyvinyl pyrrolidine (PVP), Hydroxyl propyl methyl cellulose (HPMC) E5, and HPMC E15. Twelve sets of films FN1–FN12 were prepared by solvent casting method with Pullulan and combination of Acacia, MDX, SA, LBG, GG, XG, PVA, PVP, HPMC E5 and HPMC E15. Five sets of films FS1–FS5 were prepared using synthetic polymers like PVA, PVP, HPMC E5 and HPMC E15.Results: From all the prepared polymer formulations, FN2, FN8, and FS3 were selected based on disintegration time, and drug release and amongst this three FN2 was optimised based on its disintegration time (D. T). The percent drug release of the optimised film was compared with the percent release of the pure drug.Conclusion: The optimised formulation had a D. T of 16 s and a percent drug release of 97.5% in 10 min in pH 6.8 phosphate buffer and 100.6% drug release in 10 min in 0.1N HCl.

Fabrication, Characterization and Adsorptive of Human Fibrinogen of HA/PHBV Nano Composite Films

2010 ◽  
Vol 160-162 ◽  
pp. 1325-1330
Author(s):  
Jun Yuan ◽  
Qi Xin Zheng ◽  
Jian Cheng
Keyword(s):  
Mechanical Properties ◽  
Composite Films ◽  
Nano Particles ◽  
Solvent Casting ◽  
Casting Method ◽  
Human Fibrinogen ◽  
Nano Composite ◽  
Nano Scale

In this investigation, nano-scale hydroxyapatite (HA) particles were incorporated in poly(hydroxybutyrate-co-valerate) (PHBV) polymer to fabricate composite films using solvent casting method. The morphologies, mechanical properties and adsorptive of human fibrinogen of the composite films were investigated. The HA nano-particles were dispersed in the films and well bonded to the polymer. The strength of films could be enhanced and its adsorptive of human fibrinogen could be also improved greatly by introducing HA nano-particles into the films. The results suggested these newly developed nano-HA/PHBV composite films might serve as an effective biomedicine material.

Preparation of Reduced Graphene Oxide/Chitosan Composite Films with Reinforced Mechanical Strength

2012 ◽  
Vol 430-432 ◽  
pp. 247-250 ◽  
Author(s):  
Yong Qiang He ◽  
Na Na Zhang ◽  
Wen Chao Wang ◽  
Si Yao He ◽  
Qiao Juan Gong ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Composite Films ◽  
Solvent Casting ◽  
Casting Method ◽  
X Ray ◽  
Reduced Graphene ◽  
Vis Spectroscopy ◽  
Membrane Rigidity ◽  
Chitosan Composite

Reduced graphene oxide (rGO)/chitosan composite films were fabricated by a solvent casting method and cross-linked using genipin. Their properties were characterized by scanning electron microscopy, X-ray powder diffraction, Raman spectroscopy, and UV-Vis spectroscopy. When rGO was added the tensile strength and membrane rigidity of the films increased, but their swelling ability in water decreased.

Electrostriction of Dielectric Elastomer Based on Natural Rubber/Graphene Composites for Actuator Applications

2018 ◽  
Vol 879 ◽  
pp. 32-40 ◽  
Author(s):  
Darika Jaaoh ◽  
Roseleena Jarawae ◽  
Maimoon Intan ◽  
Huseng Chaidana
Keyword(s):  
Electric Field ◽  
Natural Rubber ◽  
Composite Films ◽  
Interfacial Polarization ◽  
Dielectric Elastomer ◽  
Solution Casting ◽  
Electromechanical Properties ◽  
Casting Method ◽  
Solution Casting Method ◽  
Electric Field Induced Strain

The combination of elastic natural rubber (NR) and conductive graphene were assessed for such improved electromechanical properties that are promising material in an actuator applications. For this work, dielectric elastomer composite films were prepared with varied graphene contents. These films were fabricated by solution casting method. The morphology along with electrical and mechanical properties, and specifically the electrostrictive coefficient, were studied. The electrostrictive behavior was determined from electric field induced strain, observed with a photonic displacement apparatus in the film thickness direction. It is shown that the electrostrictive coefficient for the NR/Graphene composite has already raised over 3.7 times compared to the neat natural rubber by the reason of an interfacial polarization. The surface between NR matrix and graphene filler generates the larger permittivity. Meanwhile, the Young's modulus was quite invariant. Consequently, the enlarging of the electrostrictive coefficient under low electric field of the NR/Graphene composites is representing a potentially good actuation response base on the electrostriction phenomena.

scholarly journals Formulation and Evaluation of Transdermal Patch of Blonanserin

2021 ◽  
Vol 69 (2) ◽  
Author(s):  
Dhaval J. Patel ◽  
Saurav M. Patel ◽  
Sanjesh G. Rathi ◽  
Shrenik K. Shah
Keyword(s):  
Drug Release ◽  
Xanthan Gum ◽  
Stability Study ◽  
Solvent Casting ◽  
Transdermal Patch ◽  
Chemical Parameters ◽  
Casting Method ◽  
Transdermal Patches ◽  
Physico Chemical ◽  
Excipient Compatibility

The objective of the present study was to formulate and evaluate transdermal patch of Blonanserin. Blonanserin transdermal patches were prepared by solvent casting method using natural and synthetic polymer. Various plastisizer were screened along with polymers. Drug excipient compatibility studies concluded that the drug and excipient are compatible with each other. The prepared patches were evaluated for physico-chemical parameters to justify their suitability for transdermal use. Formulations containing Xanthan Gum with plasticizer propylene glycol gives best drug release in 8 hours. More than 90% drug release found after 8 hours in formulation F5. Hence F5 formulation is considered as optimized batch. F5 batch was found stable during stability study. Blonanserin transdermal patches were successfully prepared by solvent casting method using Xanthan Gum natural polymer.

Fabrication of Activated Carbon Filled Epoxidized Natural Rubber Composite Using Solvent Casting Method

2015 ◽  
Vol 761 ◽  
pp. 426-430
Author(s):  
Mohd Asyadi Azam ◽  
Aisyah Hassan ◽  
Noraiham Mohamad ◽  
Elyas Talib ◽  
Nor Syafira Abdul Manaf ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Activated Carbon ◽  
Natural Rubber ◽  
Polymer Composites ◽  
Epoxidized Natural Rubber ◽  
Solvent Casting ◽  
Casting Method ◽  
Rubber Composite

Despite the rapid increase in the utilization of reinforced nanomaterials composites, micromaterials may also have the potential to be utilized as filler in polymer composites. In this study, the activated carbon (AC) filled epoxidized natural rubber (ENR) composite was fabricated using the solvent casting method. AC was used as the filler at different filler addition in range from 0 to 7 parts per hundred rubbers (phr). The intention was to investigate the effect of AC filled ENR on mechanical properties and interaction between AC and ENR matrix. Overall, the result shows high improvement in mechanical properties. At 7 phr, the tensile strength was 7.0 MPa compared to 2.6 MPa for 0 phr, which indicates the increase by almost 2 times. The elongation also increases for all phr, which indicates the good filler effect.

Thermal and Mechanical Properties of PLA/BN/BR Ternary Composite Films

2016 ◽  
Vol 707 ◽  
pp. 3-7
Author(s):  
Arper Baethu ◽  
Jantrawan Pumchusak
Keyword(s):  
Thin Film ◽  
Electron Microscopy ◽  
Mechanical Properties ◽  
Thermal Properties ◽  
Composite Films ◽  
Solvent Casting ◽  
Thermal And Mechanical Properties ◽  
Casting Method ◽  
Ternary Composite ◽  
Scanning Electron

In this research, the effects of boron nitride (BN) and polybutadiene (BR) on thermal and mechanical properties of polylactic acid (PLA) composite films were studied. PLA thin film in the thickness of less than 0.2 mm was fabricated using the solvent casting method. The loadings of BN and BR of 0-7 wt% were applied to the PLA matrix. The morphologies of composite films were characterized by scanning electron microscopy (SEM). The thermal and mechanical properties were also investigated. It was found that the addition of BN and BR can improve the thermal properties of PLA composite films. PLA/BN3%/BR5% ternary composite films provided the higher thermal properties, tensile strength and Young’s modulus, compared to PLA/BN1%/BR5% ternary composite films.

Film Properties of Poly(lactic Acid) Comprising N-Methyl-2-Pyrrolidone

2012 ◽  
Vol 528 ◽  
pp. 140-143 ◽  
Author(s):  
Sasiprapa Chitrattha ◽  
Thawatchai Phaechamud
Keyword(s):  
Lactic Acid ◽  
Water Sorption ◽  
Poly Lactic Acid ◽  
Solvent Casting ◽  
Casting Method ◽  
Film Properties ◽  
Elongation At Break ◽  
Bone Fixation ◽  
The Poor ◽  
Dose Dependent

Poly (lactic acid) (PLA) has many potential uses, for example as packaging, textiles, biomedical fields, including suture, bone fixation material, drug delivery microsphere, and tissue engineering. However, PLA shows the poor toughness, slow degradation rate and relatively hydrophobic. The aim of this study was to investigate the ability of N-methyl-2-pyrrolidone (NMP) to improve the characteristics of PLA film. PLA films were prepared using a solvent casting method and their various properties were investigated. From tensile strength (TS), elongation at break (E) and young’s modulus (ε) determinations, the incorporated PLA films exhibited the softer behavior than plain PLA film. On the other hand, from the contact angle and surface free energy values, the PLA films incorporated with NMP could improve the wettability of solvents and also increased % water sorption (WS) and % weight loss (WL) than PLA films with NMP dose dependent. However SEM photographs revealed the more rather rough and cracked surface as the higher amount of NMP was incorporated in PLA film.

Design, fabrication and characterization of xanthan gum/liquid-loaded porous natural rubber film

2018 ◽  
Vol 49 (1) ◽  
pp. 149-160 ◽  
Author(s):  
Thawatchai Phaechamud ◽  
Nutdanai Lertsuphotvanit ◽  
Pongsathorn Issarayungyuen ◽  
Takron Chantadee
Keyword(s):  
Natural Rubber ◽  
Xanthan Gum ◽  
Fabrication And Characterization ◽  
Rubber Film

APPLICATIONS OF CHITOSAN-SULFATHIAZOLE AS ANTIMICROBIAL AGENT

2018 ◽  
Vol 28 (2) ◽  
pp. 429-432
Author(s):  
Dilyana Zvezdova
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Antimicrobial Agent ◽  
Defense Mechanisms ◽  
Solvent Casting ◽  
Casting Method ◽  
Gram Negative ◽  
Positively Charged

Chitosan, a hydrophilic biopolymer industrially obtained by N-deacetylation of chitin, can be applied as an antimicrobial agent. It highlights the applications of chitosan as an antimicrobial agent against fungi, bacteria, and viruses and as an elicitor of plant defense mechanisms. A series of novel chitosan-sulfathiazole nanocomposite (CSFZ) films were prepared by using solvent casting method for wound healing application. Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the interaction between negatively charged sulfathiazole and positively charged chitosan. Moreover, the antibacterial activity of the films was investigated against gram positive and gram negative microorganisms. It was found that all CSFZ films showed good inhibitory activity against all the tested bacteria as compared to control. The above analysis suggested that the CSFZ films could be used as potential candidates for wound healing application.

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