scholarly journals Characteristic differences of chest pain in male and female patients with acute coronary syndrome: A pilot study

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Yurike Olivia Sella ◽  
Halidah Manistamara ◽  
Sony Apriliawan ◽  
Mifetika Lukitasari ◽  
Mohammad Saifur Rohman
Keyword(s):  
Gender Differences ◽  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Moderate Pain ◽  
Cross Sectional ◽  
Male And Female ◽  
Female Patients ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
Pain Characteristics

Background: The typical sign or main symptom in acute coronary syndrome (ACS) patients is chest pain, which is an initial benchmark or early sign for diagnosis. Certain factors, such as gender differences, the presence of diabetes mellitus or other clinical conditions, may make the patient not realize they have ACS. Therefore, this study aims to identify the characteristics of chest pain symptoms in male and female patients with ACS.Design and Methods: This is a non-experimental quantitative study, namely analytical observation using a cross-sectional approach within 4 months (January-April 2019). Furthermore, the samples were 53 ACS patients (28 male and 25 female).Results: The chest pain characteristics that have a significant relationship with gender differences in ACS patients are shown based on the aspects of location, pain duration and quality. Male patients are more likely to feel pain at the left or middle chest, the duration is between <20 to >20 min with moderate pain quality, which tends to become severe, while females are more likely to feel pain at the chest which radiates to the neck and chin, the duration is usually >20 min, with mild to moderate pain quality.Conclusions: The result showed a significant difference in chest pain characteristics in male and female patients with ACS. Regarding location, duration and quality of chest pain, male ACS patients mostly have more typical symptoms, while females’ symptoms are atypical.

scholarly journals ACUTE CORONARY SYNDROME;

2017 ◽  
Vol 24 (03) ◽  
pp. 409-413
Author(s):  
Naveed Aslam Lashari ◽  
Nadia Irum Lakho ◽  
Sarfaraz Ahmed Memon ◽  
Ayaz Ahmed ◽  
Muhammad Fahad Waseem
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Study Results ◽  
Artery Obstruction ◽  
Conventional Risk Factors ◽  
Typical Chest Pain

Introduction: ACS is defined as the cluster of symptoms arising due to the rapiddrop of blood flow to the heart because of coronary artery obstruction. It is stated that worldwidearound 17 million people die due to cardiovascular diseases of which half of the deaths arereported due to ACS. Chest pain is known to be the most leading factor associated with ACS.Objectives: To determine the frequency of acute coronary syndrome, its types and commoncontributing factors in patients presenting with typical chest pain in a secondary care hospital.Study Design: Cross sectional study. Setting: Medical Unit, PAF Hospital Mushaf Sargodha.Period: October 2013 to March 2014. Methodology: A total of 280 patients of either gender,aged 20 to 80 years presented with typical chest pain with or without conventional risk factorswere included in the study. Results: Majority (68.9%) was males and 31.1% were female. Acutecoronary syndrome was observed in 131(46.8%) patients. Out of these 131 patients, 55% hadNSTEMI, 28.2% had unstable angina and 16.8% had STEMI. A higher proportion of femaleswere found to have ACS as compared to males (75.9% vs 33.7%, P-value<0.0001). Out of131 patients, 40.5% were diabetic, 29.8% were hypertensive 16% were hyperlipidemic, while13.7% were smokers. Conventional risk factors except smoking were observed more in femalesas compared to males. Conclusion: Majority of patients with acute coronary syndrome werefemales and diabetic. NSTEMI was the most common type of ACS. Prevalence of conventionalrisk factors was found more in females with ACS.

scholarly journals IMPACT OF GENDER ON THE CLINICAL FEATURES, ANGIOGRAPHIC FINDINGS, AND OUTCOMES OF YOUNG PATIENTS PRESENTED WITH ACUTE CORONARY SYNDROME

2022 ◽  
Vol 54 (4) ◽  
pp. 321-327
Author(s):  
Kamran Ahmed Khan ◽  
Dileep Kumar ◽  
Ayaz Hussain Shaikh ◽  
Sanam Khowaja ◽  
Mehboob Ali ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Symptom Onset ◽  
Young Patients ◽  
Cross Sectional ◽  
Men And Women ◽  
St Segment Elevation ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
Angiographic Findings

Objectives: Acute coronary syndrome (ACS) at a younger age is now becoming a crucial problem. This study determined the effect of gender on the clinical findings and outcomes of young patients (≤ 45 years) with ACS. Methodology: In this descriptive cross sectional study, young patients (≤45 years) who presented with ACS and underwent coronary angiography were recruited. The comparison of clinical profile, angiographic findings, in-hospital, and 90-days mortality between genders were made. Results: A total of 335 young patients with ACS were included, 80.6% of whom were men. A significant difference was found between men and women in terms of mean age: 38±6 vs. 40±5 (p=0.014), hypertension: 37.8% vs. 58.5% (p=0.002), diabetes: 17.4% vs. 35.4% (p=0.001), smoking: 50.4% vs. 6.2% (p≤0.001), use of smokeless tobacco: 14.1% vs. 4.6% (p=0.037), median time from symptom onset to first medical contact: 270 [420–165] minutes vs. 346 [499.5–240] minutes (p=0.047), ST-segment elevation myocardial infarction (STEMI) 89.6% vs. 78.5% (p=0.015), non-ST-elevation myocardial infarction (NSTEMI) 8.5% vs. 18.5% (p=0.019), and three-vessel disease (3VD) 10.7% vs. 21.5% (p=0.019), respectively. In-hospital and 90-day mortality rates were 0.4% vs. 3.1% (p=0.097) and 1.5% vs. 4.6% (p=0.136) for men and women, respectively. Conclusion: Women tended to have a higher age at presentation, more frequent traditional risk factors, late presentation after symptom onset, frequent NSTEMI, and 3VD, whereas men were distinct with frequent STEMI and higher tobacco use. In addition, women trended to have a higher in-hospital as well as short-term mortality than men did.

scholarly journals Acute Coronary Syndrome and patient behavior factors in overcoming the event of chest pain in pre hospital phase

2020 ◽  
Author(s):  
Cipto Susilo ◽  
Mochammad Bagus Qomaruddin ◽  
Mellani Puji Fahrera
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Complex Disease ◽  
Sampling Technique ◽  
P Value ◽  
Behavioral Factors ◽  
Cross Sectional ◽  
Over The Counter ◽  
Coronary Syndrome ◽  
Design And Methods

Background: Acute coronary syndrome (ACS) is a complex disease induced by thrombosis, which causes unstable angina (UA), acute myocardial infarction (AMI) or sudden cardiac death. It is important to rapidly detect the presence of chest pain to conduct the pre-hospital phase. This study aims to analyze the behavioral factors of patients suffering from ACS in overcoming the incidence of chest pain in the prehospital phase. Design and Methods: The consecutive sampling technique and cross-sectional method were used to obtain data from a sample of 110 outpatient respondents at the Community- Integrated Health Center.Results: After the logistic regression test, a significant relationship was found between the occurrence of chest pain (Pvalue = 0.040), with compressive behavior factors, buying over the counter drugs (P-value = 0.001), massaging and rubbing with oil (P-value = 0.046). Conclusions: In conclusion, the significant behavioral factors associated with ACS sufferers in dealing with the occurrence of chest pain in the pre-hospital phase are due to the act of buying OTC drugs and the habit of massaging or rubbing with oil.

scholarly journals Chest pain symptoms differences between diabetes mellitus and non-diabetes mellitus patients with acute coronary syndrome: A pilot study

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Halidah Manistamara ◽  
Yurike Olivia Sella ◽  
Sony Apriliawan ◽  
Mifetika Lukitasari ◽  
Mohammad Saifur Rohman
Keyword(s):  
Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Total Sample ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Adequate Knowledge ◽  
Late Treatment ◽  
Risk Patients ◽  
Pain Symptoms

Background: Chest pain is considered one of the crucial indicators in detecting acute coronary syndrome (ACS), and one of the most common complaints frequently found in hospitals. Atypical characteristics of chest pain have prevented patients from being aware of ACS. Chest pain symptoms have become ambiguous, particularly for specific parameters, such as gender, diabetes mellitus (DM), or other clinical conditions. Therefore, it is critical for high-risk patients to have adequate knowledge of specific symptoms of ACS, which is frequently associated with late treatment or prehospital delay. Therefore, this study aims to identify the particular characteristics of chest pain symptoms in DM and non-DM patients with ACS.Design and Methods: This is a quantitative and non-experimental research, with the cross-sectional approach used to carry out the analytical observation at a general hospital from January-April 2019. Data were obtained from a total sample of 61 patients, comprising 33 ACS with DM and 28 ACS non-DM patients.Results: The result showed that the characteristic of patients with chest pain symptoms has a significant relation to DM and ACS. Therefore, non-DM patients with ACS are more likely to feel chest pain at moderate to a severe level, while ACS-DM patients are more likely to have low to moderate chest pain levels.Conclusion: The significant differences in the characteristics of chest pain in DM and non-DM patients suffering from acute coronary syndrome are the points of location of chest pain radiating to the neck and quality of pain.

scholarly journals PLATELET DISTRIBUTION WIDTH VALUE AS A DIAGNOSTIC AND PROGNOSTIC MARKER IN ACUTE CORONARY SYNDROME

2018 ◽  
Vol 24 (2) ◽  
pp. 112
Author(s):  
Rahmi Rifany Latif ◽  
Liong Boy Kurniawan ◽  
Darmawati Rauf
Keyword(s):  
Acute Coronary Syndrome ◽  
Length Of Stay ◽  
Cross Sectional Study ◽  
Large Sample Size ◽  
Platelet Distribution Width ◽  
Cross Sectional ◽  
Distribution Width ◽  
Coronary Syndrome ◽  
Significant Difference ◽  
And Control

An acute coronary syndrome is a form of clinical manifestation of coronary heart disease with atherosclerosis, and thrombosis processes. Platelets play an essential role in thrombosis. High PDW shows a variation of the morphology, and size of a platelet. This was a retrospective cross-sectional study comparing PDW, length of stay, and patient outcome in STEMI, NSTEMI, UAP, and control patients at the Dr.Wahidin Sudirohusodo Hospital Makassar during the period of January 2014 – December 2015. Data were analyzed using statistical software. One hundred, and seventy-two ACS patients were included; 65 patients had UAP, 48 patients had STEMI and 59 patients had NSTEMI. Sixty normal patients were included as a control. Kruskal-Wallis test showed a statistical difference in PDW between patients with STEMI, NSTEMI, UAP, and control (p=0.000). Post hoc test showed a significant difference between ACS, and control, STEMI, and control (p=0.000), NSTEMI and control (p=0.000), UAP, and control (p=0.000), but there no significant difference     between STEMI, and NSTEMI (p=0.320), STEMI, and UAP (p=0.980), NSTEMI and UAP (p=0.435). There was no significant difference in PDW between patients who survived, and died (p=0.298), and also patients with a length of stay of ≤ 7 days, and > 7 days (p=0.293). Platelet distribution width was higher in ACS patients compared with control patients, but could not be used to predict the outcome, and length of stay of patients with ACS. It is advisable to do further research with a large sample size to avoid bias.

scholarly journals GENDER DIFFERENCES IN MYOCARDIAL REVASCULARIZATION IN INDIVIDUALS WITH ACUTE CORONARY SYNDROME AFTER CORONARY ARTERY BYPASS SURGERY

2021 ◽  
Vol 1 (6(70)) ◽  
pp. 22-29
Author(s):  
F. Ibrahimov
Keyword(s):  
Risk Factors ◽  
Gender Differences ◽  
Acute Coronary Syndrome ◽  
Artery Bypass ◽  
Myocardial Revascularization ◽  
Female Patients ◽  
Coronary Syndrome ◽  
Cerebrovascular Events ◽  
Male Patients ◽  
The Difference

The purpose of this study was to study the gender differences in the frequency of major cardiovascular and cerebrovascular events (MACCE), cardiac mortality, mortality from all other causes, and to study the relationship between these conditions and risk factors in patients after CABS. Materials and methods. The study included 717 patients after the CABS, of whom 596 were male and 121 female. Patients admitted to hospital with acute coronary syndrome (ACS) and only those undergoing CABS surgery participated in the study. All clinical data on demographic characteristics, risk factors, and complications were selected and the survival and mortality analysis was performed retrospectively. The results. In assessing the age indicator, it was found that females (59.9±7.3 years) were significantly older than males (56.3±8.2 years) (p=0.00012). In the estimation of the 30-day mortality rate, it was shown that this indicator was 3.4% for women and 0.5% for men, the differences were statistically significant (p=0.004). Identical differences were also observed for 1-year mortality, as this indicator was 3.5% for women, while for men it was 0.7% and significantly lower (p=0.012). The 5-year MACCE percentage was 19% for women and 16.9% for men, i.e. the difference was not statistically significant (p=0.585). Conclusion. The main finding of this study was the difference between the profiles of female and male populations of preoperative patients after CABS. As in other studies in this area, and in this study, female patients were older, more likely to have AH, DM, obesity and anaemia than male patients.

scholarly journals Association of mean platelet volume and acute coronary syndrome

2017 ◽  
Vol 5 (4) ◽  
pp. 1217 ◽  
Author(s):  
Hasim Ahamed ◽  
Renoy A. Henry ◽  
Rema Pai
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Mean Platelet Volume ◽  
Coronary Thrombosis ◽  
Platelet Volume ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
Significant Difference ◽  
St Elevation ◽  
The Mean

Background: Acute coronary syndrome (ACS) is a set of signs and symptoms due to rupture of a plaque and are a consequence of platelet rich coronary thrombus formation. Larger platelets are haemostatically more active and and hence carry risk for developing coronary thrombosis leading to ACS. Platelet parameters especially mean platelet volume (MPV) could be used as an important and reliable marker in early detection of ACS when the patients come to emergency department with chest pain. The primary objective is to study the association between mean platelet volume and acute coronary syndrome. The secondary objectives are to analyse if there is a statistically significant difference in mean platelet volume between Non-ST elevation (NSTEMI) and ST-elevation Myocardial Infarction (STEMI) and between double vessel disease (DVD) and triple vessel disease (TVD).Methods: A total of 260 patients were included in the study depending on the inclusion and exclusion criteria. After dividing the patients with chest pain into control (Non-cardiac chest pain) and study group (ACS) which contained 130 each, venous blood was drawn and taken to haematology laboratory for analysis of MPV within 2 hrs. The statistical analysis used were mean, median, test of significance in difference (t-test) and chi-square test.Results: Mean platelet volume (MPV) was found to be higher among ACS patients (9.4868±0.85270) as compared to control (7.430±0.72172) and it was significant with a P value <0.05. It was also noticed that MPV was higher among patients with STEMI when compared to NSTEMI, 10.32±0.77932 and 9.22±0.52743 and it was statistically significant (P<0.05). Similarly, MPV between patients with triple and double vessel disease were compared and the mean MPV of 10.04±0.88738 of TVD was greater than the mean MPV of 9.22±0.67438 in DVD and was statistically significant (P<0.05).Conclusions: In this study the MPV was higher in patients with ACS than those in control group. The study also showed that there was significant difference in MPV values between people with STEMI and NSTEMI and between people with DVD and TVD. Hence it might be useful as an additional cost efficient test in conjunction with other markers in the early prediction of ACS in the emergency room. Larger platelets are haemostatically more active and hence carry risk for developing coronary thrombosis leading to ACS. Patients with increased MPV could be easily identified during routine haematological analysis and hence could play an important role in early detection of acute coronary syndrome (ACS).

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