scholarly journals Intravesical prostaglandin e2 effectiveness in the prevention of urinary retention after transvaginal reconstruction of the pubo-cervical fascia and short arm sling according to Lahodny: a prospective randomized clinical trial

2010 ◽  
Vol 14 (1) ◽  
pp. 15 ◽  
Author(s):  
G. QUADRI ◽  
N. NATALE ◽  
C. SPREAFICO ◽  
C. BELLONI ◽  
D. BARISANI ◽  
...  
Keyword(s):  
Prostaglandin E2 ◽  
Urinary Retention ◽  
Study Groups ◽  
T Test ◽  
Control Group ◽  
Fisher Exact Test ◽  
Test Results ◽  
Exact Test ◽  
Student’S T ◽  
Student’S T Test

Intravesical prostaglandin E2 is effective in the recovery of spontaneous voiding after transvaginal reconstruction of the pubocervical fascia and short arm sling according to Lahodny. The aim of the study was to compare the effects of intravesical prostaglandin E2 in the prevention of urinary retention after transvaginal reconstruction of the pubocervical fascia and short arm sling according to Lahodny. STUDY DESIGN: From November 1996 to June 1999 fifty women underwent the Lahodny procedure for moderate/severe cystocele and stress urinary incontinence. Women were randomly assigned to 1 of the 2 study groups: intravesical prostaglandin E2 versus controls. Data obtained were analyzed with the Student t test and the Fisher exact test. RESULTS: Two patients of the treatment group had to be excluded from the study, one because of the wrong measurement of the post-voidal residual volume and another due to a fastidious burning sensation which appeared immediately after prostaglandin instillation and required the suspension of the treatment. No other side effects such as nausea, vomiting, diarrhea or hyperthermia were observed. Patients who underwent the prostaglandin E2 treatment showed a recovery of spontaneous voiding after 7.9±6.7 days, whereas this interval was significantly longer in the control group, being 12.9±9.7 days (p=0.04, Two tailed Unpaired Student's T test). CONCLUSION: The effectiveness and the low associated morbidity mark the treatment with intravesical prostaglandin E2 useful in the recovery of normal voiding after transvaginal pubocervical fascia reconstruction and short arm sling with the procedure according to Lahodny.

scholarly journals Study of Relationship of Anemia among Edentulous Patients

2018 ◽  
Vol 5 (2) ◽  
pp. 105-108
Author(s):  
Lijo Isaac ◽  
A. P. Nirmal Raj ◽  
Reshma Karkera ◽  
R Naveen Reddy
Keyword(s):  
Nutritional Status ◽  
T Test ◽  
Dental Status ◽  
Adult Patients ◽  
Control Group ◽  
Age Group ◽  
Edentulous Patients ◽  
Student’S T ◽  
Relationship Of ◽  
Student’S T Test

Very little studies were done on relationship of the dental status and the nutritional status. The present study was done to study relation between edentulism and the presence of anemia. The study was included of 46 adult patients with edentulism and same numbers of patients were taken as controls. The results were tabulated and analyzed with the help of IBM SPSS statistics 20 using student’s t test. The hemoglobin levels were lower in the edentulous patients that that of the control group. The present study had shown that the nutritional status were poor resulting in anemia in case of edentulous patients as compared to control group with the same age group.  

scholarly journals Air Rebusan Seledri Menurunkan Tekanan Darah

2015 ◽  
Vol 6 (2) ◽  
Author(s):  
Wiwik Afridah ◽  
Budi Setiawan
Keyword(s):  
Blood Pressure ◽  
Elderly People ◽  
Elderly Population ◽  
Fruits And Vegetables ◽  
Healthy Lifestyle ◽  
Control Group ◽  
Fisher Exact Test ◽  
Random Allocation ◽  
Test Results ◽  
Exact Test

The increasing elderly population will lead to problems such as health problems, one of which is hypertension. The purpose of this study was to determine the effect of celery stew on blood pressure in elderly people with hypertension Hulaan Village District Menganti Gresik regency. This study uses a design Case control design with the aging population in the first level of hypertension by 12 people, with a large sample of elderly with hypertension entire first level is 12 people, and how to use the total sampling sampling and divided into 6 groups of 6 cases and the control group with random allocation techniques. Celery stew independent variables and the dependent variable blood pressure. The data was collected by means of measuring the blood pressure recorded recapitulation and analyzed using the Fisher exact test with α = 0.05. The research results obtained from 6 groups of cases that were given celery stew all experienced a decrease in blood pressure, whereas in the control group of 6 people who were not given celery stew is only 1 person that declined. Fisher Exact test results obtained ρ (0.015) <α (0.05), means that the research hypothesis is accepted ie no celery stew effect on blood pressure in elderly people with hypertension Hulaan Village District Menganti Gresik Regency. The conclusions of this study are no celery stew effect on blood pressure of elderly with hypertension. Hypertensive patients are expected to maintain your diet, multiply to consume fruits and vegetables that contain potassium, as well as a healthy lifestyle change. 

scholarly journals Effects of early unilateral mandibular first molar extraction on condylar and ramal vertical asymmetry

2014 ◽  
Vol 08 (02) ◽  
pp. 178-183 ◽  
Author(s):  
Koray Halicioglu ◽  
Mevlut Celikoglu ◽  
Suleyman K. Buyuk ◽  
Ahmet E. Sekerci ◽  
Celal Candirli
Keyword(s):  
Asymmetry Index ◽  
T Test ◽  
Control Group ◽  
Missing Teeth ◽  
Anterior Crowding ◽  
Mandibular Asymmetry ◽  
Group I ◽  
Student’S T ◽  
Mandibular First Molar ◽  
Student’S T Test

ABSTRACT Objective: The objective of the following study is to investigate the mandibular vertical asymmetry in a group of patients with early unilateral mandibular first molar extractions. Materials and Methods: Mandibular asymmetry index measurements (condylar, ramal and condylar-plus-ramal) were performed on the panoramic radiographs of a study group including 51 patients (mean age: 18.60 ± 1.11 years) and a control group of 51 patients (mean age: 18.53 ± 1.29 years). Group I included patients with a unilateral mandibular first molar extracted before the age of 12 years. Group II included patients with no extractions and had excellent Class I relationships, no missing teeth and slight or moderate anterior crowding. A paired t-test was used to determine possible statistically significant differences between the sides for the measurements. Student's t-test was used for the comparison of asymmetry index values between the groups and genders. Results: No group showed statistically significant sex-or side-specific differences for posterior vertical height measurements. Condylar asymmetry index and ramal asymmetry index measurements were not statistically different between the groups, while condylar-plus-ramal asymmetry index (CRAI) measurements were statistically different between the groups (P = 0.019). Conclusions: A slight difference for CRAI value was found in patients with early unilateral mandibular first molar extractions.

18 EMBRYO AGGREGATION IN PIG IMPROVES CLONING EFFICIENCY AND EMBRYO QUALITY

2016 ◽  
Vol 28 (2) ◽  
pp. 139
Author(s):  
C. Buemo ◽  
A. Gambini ◽  
L. Moro ◽  
R. F. Y. Martin ◽  
D. Salamone
Keyword(s):  
In Vitro Culture ◽  
Dna Fragmentation ◽  
Embryo Development ◽  
Embryo Quality ◽  
T Test ◽  
Control Group ◽  
Reconstructed Embryo ◽  
Student’S T ◽  
Student’S T Test

In this study, we analysed the effects of the cloned embryo aggregation on in vitro embryo development and embryo quality by measuring blastocyst size and cell number, DNA fragmentation levels by TUNEL assay, and the relative expression of genes associated with pluripotency, apoptosis, trophoblast markers, and DNA methylation in the porcine. Cumulus-oocyte complexes were recovered from slaughterhouse ovaries by follicular aspiration. Maturation was performed in TCM for 42 to 48 h at 39°C and 5% CO2. After denudation by treatment with hyaluronidase, mature oocytes were stripped of the zona pellucida using a protease and then enucleated by micromanipulation; staining was performed with Hoëchst 33342 to observe metaphase II. Ooplasms were placed in phytohemagglutinin to permit different membranes to adhere between each other; the ooplasm membrane was adhered to a porcine fetal fibroblast from an in vitro culture. Adhered membranes of the donor cell nucleus and enucleated oocyte cytoplasm were electrofused through the use of an electric pulse (80 V for 30 μs). All reconstituted embryos were electrically activated using an electroporator in activation medium (0.3 M mannitol, 1.0 mM CaCl2, 0.1 mM MgCl2, and 0.01% polyvinyl alcohol) by a DC pulse of 1.2 kVcm for 80 μs. Then, embryos were incubated in 2 mM 6-DMAP for 3 h. In vitro culture of zona-free embryos was achieved in a well of wells system in 100 μL of SOF medium. Two experimental groups were used, one control group with a single reconstructed embryo per microwell (1×) and the other group placing 3 reconstructed embryo per microwell (3x aggregation group). Embryos were cultivated at 39°C in 5% O2, 5% CO2 for 7 days in SOF medium with a supplement of 10% fetal bovine serum on the fifth day. At Day 7, resulting blastocysts were classified according to their morphology and diameter to determine their quality. Our results showed that aggregation of 3× embryos increased blastocyst formation rate and blastocyst size of pig cloned embryos (Fisher’s test P < 0.05 and Student’s t-test P < 0.05, respectively). The DNA fragmentation levels in 3× aggregated cloned blastocysts were significantly decreased compared to 1x blastocyst (Student’s t-test P < 0.05). Levels of Oct4, Klf4, Igf2, Bax, and Dnmt1 transcripts were significantly higher in aggregated embryos, whereas Nanog levels were not affected. Transcripts of Cdx2 and Bcl-xl were essentially nondetectable (Student’s t-test P < 0.05). Our study suggests that embryo aggregation in the porcine may be beneficial for cloned embryo development and embryo quality, through a reduction in apoptotic levels and an improvement in cell reprogramming.

26 Drugs that Modify Epigenetics...What do they do to Porcine Clones?

2018 ◽  
Vol 30 (1) ◽  
pp. 152
Author(s):  
C. P. Buemo ◽  
A. Gambini ◽  
L. N. Moro ◽  
N. Canel ◽  
D. F. Salamone
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Electric Pulse ◽  
Donor Cell ◽  
T Test ◽  
Control Group ◽  
Developmental Rates ◽  
Student’S T ◽  
Student’S T Test

Although somatic cell nuclear transfer (SCNT) technology was developed more than 20 years ago, cloning efficiency remains low. Failures in the reprogramming of the donor cell result in embryos with aberrant epigenetic patterns and low developmental rates. In this study, we assessed whether the use the inhibitor of DNA (cytosine 5) methyltransferase 5-azacitidine (5Aza) combined with the MEK inhibitor in the MAPK pathway PD0325901 (PD) could improve SCNT efficiency in pigs. In vitro maturation of cumulus–oocyte complexes was performed in TCM for 44 h at 39°C under 5% CO2. Cumulus cells and zona pellucida was removed from matured oocytes, followed by enucleation of the metaphase plate previously stained with Hoëchst 33342. Each enucleated oocyte was attached to a donor cell by phytohemagglutinin treatment followed by an electric pulse of 80V for 30 μs. After fusion, reconstituted embryos were activated by an electric pulse followed by an incubation in 2 mM 6-DMAP for 3 h. Cloned embryos were cultured in vitro in a modified well-of-well system in SOF medium, where 3 cloned embryos were placed per microwell (3X). The experimental group 3X + drugs was exposed for the first 3 days to 1 μM PD and 1 μM 5Aza in SOF medium. After washing, embryos were cultured until Day 7 in regular SOF medium. The control group (3X) was cultured in regular SOF medium for 7 days. In vitro embryo developmental rates, gene expression, histone acetylation, and DNA methylation status were studied. The use of epigenetic modifying drugs significantly increased blastocyst rates (40.9% v. 29%; Fisher’s test, P < 0.05) and embryo size (41.46% v. 28.56%; Student’s t-test, P < 0.05) compared with the control group. Regarding gene expression, an increase of the relative expression of genes related to cell differentiation (Igf2 and Cdx2), antiapoptotic pathways (Bcl-xl) and DNA methylation modulation (Mapk1) was observed (P < 0.05). Pluripotency genes Oct4 and Nanog did not show differences between groups. The Bax proapoptotic gene significantly decreased its expression after drug treatment, as did the Klf4 gene (P < 0.05). Results were analysed by Student’s t-test. According to Histone H3K27ac, which is associated with enhancers or gene promoters, its marker was located mainly in the nuclear periphery respect to the control group with a uniform dispersion, indicating that the treatment could be activating certain genes by locating them near the periphery. Histone H3K4me1 was more uniformly localised throughout the nucleus in both groups. The intensity of the fluorescence was measured by quantitative confocal microscopy using a histogram produced by the ImageJ program (National Institutes of Health, Bethesda, MD, USA). Regarding DNA methylation by bisulphite sequencing, the 2 genes studied (Oct4 and DNMT1) showed a higher demethylation status for the treated group. Our results indicate that the combination of 5Aza+PD during early pre-implantation development dramatically increase blastocyst rates and embryo quality. This novel combination could be used as a strategy to improve the efficiency of SCNT in pigs and potentially other animals.

scholarly journals Evaluating the Effect of Slow-Stroke Back Massage on the Anxiety of Candidates for Cataract Surgery

2019 ◽  
Vol 12 (2) ◽  
pp. 12-17
Author(s):  
Maryam Keramati, MD ◽  
Mohammad Sadegh Sargolzaei, MSc ◽  
Ali Moghadasi ◽  
Mohammad Hasan Basirinezhad, MSc ◽  
Reza Mohammadpourhodki
Keyword(s):  
Cataract Surgery ◽  
Intervention Group ◽  
T Test ◽  
Control Group ◽  
Paired Samples ◽  
Significant Difference ◽  
Student’S T ◽  
Dependent Samples ◽  
Student’S T Test ◽  
Back Massage

Background: The patients under cataract sur-gery often experience anxiety not only during the surgery, but also prior to the surgery.Purpose: We sought to determine the effects of slow-stroke back massage on anxiety in patients undergoing cataract surgery. Setting: The study was conducted in the Amiral-momenin Hospital of Zabol city, south-east of Iran.Participants: A total of 60 candidates of cataract surgery participated in the study.Research Design: The participants were ran-domly allocated to either control or intervention groups. The intervention group received slow-stroke back massages, while patients in control group received routine interventions.Intervention: The slow-stroke back massage was performed on the patients assigned to the interven-tion group. The intervention was performed in the morning of the surgery day at 30 minutes before the surgery. The researcher performed each mas-sage session in a sitting position. The duration of each massage session was 15 minutes. Main Outcome Measures: Anxiety was assessed in the both groups in the morning of the surgery, before and immediately after the intervention. In-dependent samples Student’s t test, paired samples Student’s t test, and chi-squared test were used to analyze the data.Results: Anxiety was not significantly different between the two groups before and after the mas-sage (p = .816). On the other hand, paired samples Student’s t test showed a significant difference comparing the anxiety scores before (49.7±5.43) and after (45.16±3.89) the massage in the interven-tion group (p < .001). Conclusions: Based on our results, slow-stroke back massage, which is a low-cost and safe method, reduced anxiety in patients who were candidates for cataract surgery.

scholarly journals Diastasis recti abdominis during pregnancy and 12 months after childbirth: prevalence, risk factors and report of lumbopelvic pain

2016 ◽  
Vol 50 (17) ◽  
pp. 1092-1096 ◽  
Author(s):  
Jorun Bakken Sperstad ◽  
Merete Kolberg Tennfjord ◽  
Gunvor Hilde ◽  
Marie Ellström-Engh ◽  
Kari Bø
Keyword(s):  
Risk Factors ◽  
Post Partum ◽  
Fisher Exact Test ◽  
Significance Level ◽  
Exact Test ◽  
Diastasis Recti ◽  
Student’S T ◽  
First Time ◽  
Diastasis Recti Abdominis ◽  
Student’S T Test

Background/aimDiastasis recti abdominis (DRA) is defined as a separation of the 2 muscle bellies of rectus abdominis. To date there is scant knowledge on prevalence, risk factors, and consequences of the condition. The present study aimed to investigate the prevalence of DRA during pregnancy and post partum, presence of possible risk factors, and the occurrence of lumbopelvic pain among women with and without DRA.MethodsThis prospective cohort study followed 300 first-time pregnant women from pregnancy till 12 months post partum. Data were collected by electronic questionnaire and clinical examinations. DRA was defined as a palpated separation of ≥2 fingerbreadths either 4.5 cm above, at or 4.5 cm below the umbilicus. Women with and without DRA were compared with independent samples Student's t-test and χ2/Fisher exact test, and OR with significance level >0.05.ResultsPrevalence of DRA was 33.1%, 60.0%, 45.4%, and 32.6% at gestation week 21, 6 weeks, 6 months and 12 months post partum, respectively. No difference in risk factors was found when comparing women with and without DRA. OR showed a greater likelihood for DRA among women reporting heavy lifting ≥20 times weekly (OR 2.18 95% CI 1.05 to 4.52). There was no difference in reported lumbopelvic pain (p=0.10) in women with and without DRA.ConclusionsPrevalence of mild DRA was high both during pregnancy and after childbirth. Women with and without DRA reported the same amount of lumbopelvic pain 12 months post partum.

scholarly journals Histological study of tendon healing in malnourished Wistar rats treated with ultrasound therapy

2006 ◽  
Vol 21 (suppl 4) ◽  
pp. 13-17 ◽  
Author(s):  
Paulo de Tarso Camillo de Carvalho ◽  
Iandara Schettert Silva ◽  
Filipe Abdalla dos Reis ◽  
Ana Carulina Guimarães Belchior ◽  
Ricardo Dutra Aydos ◽  
...  
Keyword(s):  
Histological Study ◽  
Healing Process ◽  
Statistical Treatment ◽  
Tendon Healing ◽  
Tendon Injuries ◽  
Control Group ◽  
Test Results ◽  
Leukocyte Counts ◽  
Student’S T ◽  
Student’S T Test

PURPOSE: To investigate the effects of therapeutic ultrasound on the healing of tendon injuries in malnourished rats. METHODS: After the intended nutritional states had been attained, the animals (N=36) were distributed into three groups, named: G1(N=12), control group; G2(N=12), malnourished rats treated with 3 MHz ultrasound at an intensity of 0.5 W/cm²; and G3 (N=12), normal animals treated with 3 MHz at 0.5 W/cm². The injuries were induced by means of an operation to expose the heel tendon and crush it using Allis forceps. RESULTS: The data obtained relating to leukocyte counts, fibroblasts, vessel neoformation, fibrosis and collagen were subjected to statistical treatment using analysis of variance (ANOVA) and Student's t test. Results of p < 0.05 were obtained for fibrosis and collagen. CONCLUSION: The ultrasound was shown to be effective in repairing the tendon, even in malnourished animals whose healing process was retarded.

scholarly journals Artifact induction by endodontic materials

2019 ◽  
Author(s):  
Fernanda Cristina Sales Salineiro ◽  
Igor Publio Talamoni ◽  
Solange Kobayashi Velasco ◽  
Fabiana Mesquita Barros ◽  
Marcelo De Gusmão Paraíso Cavalcanti
Keyword(s):  
Region Of Interest ◽  
T Test ◽  
Control Group ◽  
Distribution Analysis ◽  
Subjective Analysis ◽  
Gutta Percha ◽  
Student’S T ◽  
The One ◽  
Student’S T Test

Metallic objects, such as intracanal posts and restorations, may produce severe interference, thus diminishing the quality of CBCT imaging. Objective: The purpose of this study was to analyze the influence of conventional and bioceramic gutta-percha points on the production of artifacts in CBCT images. Methods: Extracted single- -rooted premolar teeth (n=20) were instrumented and scanned with a CBCT device to create three groups: the Control group, the Gutta-Percha group and the Bioceramic Gutta-Percha group. Two types of analysis were executed: an objective one, using the Region of Interest (ROI) to measure the pixel density of each tooth, and a subjective one, to compare the groups’ images. For the statistical analysis, Student’s t-test, descriptive statistics and the frequency distribution analysis were used for both objective and subjective analyses. Results: The agreement between the observers ranged from moderate to excellent. Similar grayscale values were obtained in both the GP and BCGP groups. These results were endorsed by the p-values obtained with Student’s t test. For the subjective analysis, the observers indicated the BCGP group as the one that developed the highest number of artifacts. Conclusions: Both materials produced artifacts in the CBCT images. However, in the subjective analysis, the BCGP group showed higher levels of artifact production than the GP group, which could result in the misdiagnosis of root fracture and in a worse prognosis for that tooth.

Condylar Asymmetry Measurements in Patients with Temporomandibular Disorders

2004 ◽  
Vol 5 (3) ◽  
pp. 59-65 ◽  
Author(s):  
Ali Alp Sağlam ◽  
Gülperi Şanli
Keyword(s):  
Temporomandibular Disorders ◽  
Asymmetry Index ◽  
T Test ◽  
Control Group ◽  
The Mean ◽  
Student’S T ◽  
The Relationship ◽  
Experimental Group ◽  
Student’S T Test

Abstract Objectives The relationship between condylar asymmetry and handedness of the patients with temporomandibular disorders (TMD) and patients with no signs or symptoms of TMD was investigated. The experimental group consisted of 25 patients aged 15 to 52 years who were referred for treatment of TMD. The mean age of this group was 26.24 years. The control group consisted of 25 patients aged 14 to 52 years (mean age: 26.16 years). Methods The formula by Habets et al.14 was used to express the symmetry between the condyles and the rami on the orthopantomogram (OPG) image. Differences between bothgroups and subgroups (condyle, ramus, condyle plus ramus) regarding symmetry were calculated with the Student's t-test. Results The mean of condylar asymmetry was found to be 11.11 ± 11.03% in the TMD group. However, in the control group, the mean of condylar asymmetry was found to be 8.36 ± 6.27%. No statistically significant differences were found between condylar asymmetry in both groups (p>0.05). Conclusions No statistically significant differences were found between condylar asymmetry index in patients with TMD according to myogenous problems and in patients with no signs or symptoms of TMD. Citation Sağlam AA, Şanli G. Condylar Asymmetry Measurements in Patients with Temporomandibular Disorders. J Contemp Dent Pract 2004 August;(5)3:059-065.

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