scholarly journals Prevalence of metabolic syndrome in south indian patients with psoriasis vulgaris and the relation between disease severity and metabolic syndrome: A hospital-based case-control study or cross-sectional study?

2013 ◽  
Vol 58 (4) ◽  
pp. 315
Author(s):  
DevinderMohan Thappa ◽  
Divya Gupta
Keyword(s):  
Metabolic Syndrome ◽  
Disease Severity ◽  
Psoriasis Vulgaris ◽  
Case Control Study ◽  
Cross Sectional Study ◽  
Case Control ◽  
Sectional Study ◽  
Cross Sectional ◽  
South Indian ◽  
Control Study

scholarly journals Leukoedema pada Perokok

e-GIGI ◽  
2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Priska T. Mambu ◽  
Pieter L. Suling ◽  
Aurelia S. R. Supit
Keyword(s):  
Case Control Study ◽  
Cross Sectional Study ◽  
Case Control ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cigarette Smokers ◽  
Review Study ◽  
Cross Sectional Studies ◽  
Almost All ◽  
Control Study

Abstract: Smokers can be found in almost all groups of people worldwide since cigarettes can be obtained easily anywhere and have been addicted by adult smokers. Leukoedema is one of the lesions in oral cavity that most often appears in smokers. This study was aimed to obtain the description of leukoedema cases among smokers. This was a literature review study. This study used previous studies or reports related to leukoedema in smokers. There were 13 literatures in this study consisting of 9 cross-sectional studies, 3 cohort studies, and 1 case control study. The results showed that leukoedema lesions were more common in smokers than in those who consumed tobacco. Leukoedema was closely related to the duration of smoking and the frequency of smoking in a day. Leukoedema was also more common in men than in women, and was often found bilaterally on the buccal mucosa. In conclusion, leucoedema was most common in cigarette smokers and was related to duration of smoking, frequency of smoking per day, and sex. It was often found bilaterally on the buccal mucosa.Keywords: smokers, leukoedema Abstrak: Perokok ditemukan pada hampir semua kelompok masyarakat di dunia. Leukoedema merupakan salah satu lesi dalam rongga mulut yang paling sering muncul pada perokok. Penelitian ini bertujuan untuk mengetahui gambaran leukoedema pada perokok. Jenis penelitian ialah studi pustaka. Penelitian ini menggunakan topik terkait leukoedema pada perokok dari penelitian-penelitian sebelumnya. Pustaka yang diulas dan dipelajari dalam penelitian ini sebanyak 13 pustaka, terdiri dari 9 cross-sectional study, 3 cohort study, dan 1 case control study. Hasil penelitian ini memperlihatkan bahwa lesi leukoedema lebih sering ditemukan pada perokok dibandingkan yang tidak merokok meskipun mengonsumsi tembakau. Leukoedema erat hubungannya dengan lama kebiasaan merokok dan frekuensi merokok yang dilakukan dalam sehari. Leukoedema juga lebih sering ditemukan pada laki-laki dibandingkan perempuan, dan sering ditemukan pada mukosa bukal secara bilateral. Simpulan penelitian ini ialah leukoedema sering didapatkan pada perokok dan berhubungan erat dengan kebiasaan merokok, frekuensi merokok, jenis kelamin, dengan lokasi mukosa bukal bilateral.Kata kunci: perokok, leukoedema

scholarly journals Faktor-Faktor Yang Mempengaruhi Tuberculosis Multidrug Resistance (TB MDR)

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Trivianto G. Bawonte ◽  
Christi D. Mambo ◽  
Angelina S. R. Masengi
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Multidrug Resistance ◽  
Literature Review ◽  
Case Control Study ◽  
Cross Sectional Study ◽  
Case Control ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mdr Tb ◽  
Control Study

Abstract: Multidrug Resistance Tuberculosis (MDR TB) is Mycobacterium tuberculosis resistance to the first line of antituberculosis drugs are rifampicin and isoniazid. Globally, in 2017 there were around 558.000 new cases (range, 483.000-639.000) resistant TB rifampicin (TB RR), nearly half of which were in three counties, India (24%), China (13%), and Rusia (10%). WHO estimates that there are 23.000 cases of MDR/RR in Indonesia. In 2017, there were 442.000 TB cases recorded in the program, of which an estimated 8.600-15.000 MDR/RR TB cases. The research to determine the factors that influence Multidrug Resistance Tuberculosis (MDR TB).this type of research is in the form of literature review with design of case control study and cross sectional study. The results showed that the risk factors were proven to influence the occurrence (MDR TB). The conclusion from 15 articles reviewed, it shows that age, gender, treatment irregularity and medication adherence are the most influencing factors for TB MDR.Keywords: Factors, TB MDR, multidrug resistance tuberculosis  Abstrak: Tuberculosis Multidrug Resistance (TB MDR) merupakan resistensi Mycobacterium tuberculosis terhadap jenis Obat Anti Tuberkulosis (OAT) lini pertama yaitu rifampisin dan isoniazid. Di tingkat global, di tahun 2017 terdapat sekitar 558.000 kasus baru (rentang, 483.000 - 639.000) TB rifampisin (TB RR) resistan di mana hampir separuhnya ada di tiga negara yaitu India (24%), China (13%), dan Rusia (10%). WHO memperkirakan ada 23.000 kasus MDR/RR di Indonesia. Pada tahun 2017 kasus TB yang tercatat di program ada sejumlah 442.000 kasus yang mana dari kasus tersebut diperkirakan ada 8.600-15.000 MDR/RR TB. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi Tuberculosis Multidrug Resistance (TB MDR). Jenis penelitian ini berbentuk literature Review dengan rancangan case control study dan cross sectional study. Hasil penelitian ini menunjukkan bahwa faktor risiko terbukti mempengaruhi terjadinya (TB MDR). simpulan dari 15 artikel yang di review, menunjukkan bahwa usia, jenis kelamin, ketidakteraturan berobat, dan kepatuhan minum obat merupakan faktor yang paling mempengaruhi terjadinyaTB MDR.Kata Kunci : Faktor – faktor, TB MDR, factors, multidrug tuberculosis

scholarly journals Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study

2011 ◽  
Vol 164 (3) ◽  
pp. 381-388 ◽  
Author(s):  
Chloe Y Y Cheung ◽  
Annette W K Tso ◽  
Bernard M Y Cheung ◽  
Aimin Xu ◽  
K L Ong ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Genetic Risk ◽  
Chinese Population ◽  
Central Obesity ◽  
Case Control Study ◽  
Case Control ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Control Study

ObjectiveCentral obesity predisposes to various cardiometabolic diseases and is a key component of the metabolic syndrome (MetS). We have previously demonstrated that three obesity-susceptible single nucleotide polymorphisms (SNPs), rs10938397 (GNPDA2), rs8050136 (FTO) and rs17782313 (MC4R), were associated with obesity and waist circumference in cross-sectional studies in the Chinese population. In this study, we investigate whether these SNPs could also predict the persistence of central obesity and MetS in subjects from the Hong Kong Cardiovascular Risk Factors Prevalence Study (CRISPS) cohort.Design and methodsWe genotyped these SNPs in i) 354 subjects with and 994 subjects without central obesity at both baseline and a 12-year follow-up, ii) 2214 subjects (816 cases and 1398 controls) in an MetS cross-sectional case–control study and iii) 225 subjects with and 1221 subjects without MetS at both baseline and the 12-year follow-up.ResultsBoth FTO rs8050136 (Page, sex-adjusted=0.019; odds ratio (OR) (95% confidence intervals (CI)): 1.35 (1.05, 1.73)) and GNPDA2 rs10938397 (Page, sex-adjusted=3×10−3; OR (95% CI): 1.34 (1.11, 1.63)) were significantly associated with persistent central obesity. GNPDA2 rs10938397 was also significantly associated with MetS (Page, sex-adjusted=0.011, OR (95% CI): 1.20 (1.04, 1.38)) in the case–control study. However, none of these SNPs showed an individual association with persistent MetS. In the combined genetic risk analyses for persistent central obesity and persistent MetS, the combined genetic risk score of the three SNPs showed an OR of 1.25 (95% CI: 1.10, 1.42; Page, sex-adjusted=4.92×10−3) and 1.19 (95% CI: 1.03, 1.38; Page, sex-adjusted=0.019) for each additional risk allele respectively.ConclusionThis study demonstrated that FTO and GNPDA2 variants predicted persistent central obesity in the Chinese population, further supporting their importance as obesity-susceptible genes.

scholarly journals Psoriasis and metabolic syndrome: hospital based cross sectional study of prevalence and correlation in a rural south Indian population

2016 ◽  
Vol 2 (3) ◽  
pp. 49
Author(s):  
Dhanalakshmi Kathirvel ◽  
Vaishnavi Dhandapani ◽  
Baskaran R. ◽  
Gladius Jennifer H.
Keyword(s):  
Metabolic Syndrome ◽  
Lifestyle Modification ◽  
Normal Population ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
South Indian ◽  
Chi Square Test

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic inflammatory skin disease that affects 1-3% of the population. Recent studies have reported that psoriasis is associated with metabolic disorders, including obesity, dyslipidaemia and diabetes. The aim of the present study was to investigate the prevalence of metabolic syndrome (MS) in psoriasis and to evaluate the association with severity and duration of psoriasis</p><p class="abstract"><strong>Methods:</strong> This was a hospital based cross sectional study that involved 60 patients with psoriasis evaluated for MS. Statistical analysis was done by SPSS version 16.0 software. Percentages, mean, standard deviation, correlation, chi-square test, t test were calculated at 5% level of significance.<strong></strong></p><p class="abstract"><strong>Results:</strong> 20% of patients had MS which is comparable to the normal population. 60% of the patients in our study are obese which is directly correlating with MS. There is significant increase in MS as age (p =0.01), duration of psoriasis (p =0.03), BMI (p =0.0001), waist circumference (p =0.0001) increases.</p><p><strong>Conclusions:</strong> There is 20% association of psoriasis with MS. There is no gender predisposition and no association between the severity of psoriasis and metabolic syndrome. There is minimal relationship between the duration of psoriasis and metabolic syndrome. Obesity is the commonest factor related to psoriasis, diabetes and MS which should be taken care of by diet, exercise and lifestyle modification. </p>

scholarly journals Assessment of the Effect of Metabolic Syndrome on the Autophagy Marker LC3 in Psoriasis Vulgaris Patients: A Cross-Sectional Study

2020 ◽  
Vol Volume 13 ◽  
pp. 1005-1013
Author(s):  
Essam A Nada ◽  
Eman MS Muhammad ◽  
Sheren FM Ahmed ◽  
Asmaa MS Tamam ◽  
Amr Abdelhamed
Keyword(s):  
Metabolic Syndrome ◽  
Psoriasis Vulgaris ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Awareness of the use of hyponatraemia-inducing medications in older adults with hyponatraemia: a study of their prevalent use and association with recurrent symptomatic or severe hyponatraemia

2020 ◽  
Author(s):  
Kwanghee Jun ◽  
Yujin Kim ◽  
Young-Mi Ah ◽  
Ju-Yeun Lee
Keyword(s):  
Older Patients ◽  
Case Control Study ◽  
Cross Sectional Study ◽  
Case Control ◽  
Thiazide Diuretics ◽  
Cross Sectional ◽  
Severe Hyponatraemia ◽  
Prescription Rates ◽  
The Impact ◽  
Control Study

Abstract Background Cautious use or avoidance of hyponatraemia-inducing medications (HIMs) is recommended in older patients with hyponatraemia. Objective To evaluate the use of HIMs after treatment for symptomatic or severe hyponatraemia and to investigate the impact of HIMs on the recurrence of symptomatic or severe hyponatraemia in older patients. Design and settings A cross-sectional and nested case–control study using data obtained from national insurance claims databases. Methods The rate of prescribing HIMs during the 3 months before and after the established index date was analysed in a cross-sectional analysis. Multivariable logistic regression was performed to investigate the association between HIM use and recurrence of symptomatic or severe hyponatraemia after adjusting for covariates in a case–control study. Results The cross-sectional study included 1,072 patients treated for symptomatic or severe hyponatraemia. The proportion of patients prescribed any HIMs after hyponatraemia treatment decreased from 76.9 to 70.1%. The prescription rates significantly decreased for thiazide diuretics (from 41.9 to 20.8%) and desmopressin (from 8.6 to 4.0%), but the proportion of patients prescribed antipsychotics increased from 9.2 to 17.1%. Of 32,717 patients diagnosed with hyponatraemia, 913 (2.8%) showed recurrent hyponatraemia. After adjusting for comorbid conditions, the use of any HIMs including proton pump inhibitors [adjusted odds ratio (aOR) 1.34, 95% confidence interval (CI) 1.15–1.57] and two or more HIMs (aOR 1.48, 95% CI 1.22–1.78) especially in combination with thiazide diuretics increased the likelihood of severe hyponatraemia recurrence. Conclusions Prevalent use of HIMs after treatment for symptomatic or severe hyponatraemia and multiple HIM use increase the risk of recurrent hyponatraemia in geriatric patients.

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