scholarly journals Primary Nasal Tuberculosis: Resurgence or Coincidence − A Report of Four Cases with Review of Literature

2017 ◽  
Vol 9 (01) ◽  
pp. 026-030 ◽  
Author(s):  
Sabina Khan ◽  
Mukta Pujani ◽  
Sujata Jetley
Keyword(s):  
Clinical Presentation ◽  
Tertiary Care ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Female Ratio ◽  
Antituberculous Treatment ◽  
Hematoxylin And Eosin ◽  
Hematoxylin And Eosin Stain ◽  
Male To Female

ABSTRACT Background: Primary nasal tuberculosis (TB) is a rare form of TB even in areas with high TB incidence. It is timely diagnosis and proper management are often delayed due to its rarity and nonspecific clinical presentation. Aim: The aim of the study was to review histopathologically diagnosed cases of nasal TB over a period of 1 year and to describe its clinical presentation, diagnostic workup, the importance of histopathological diagnosis along with a brief review of the literature. Materials and Methods: This was a retrospective study done in the Department of Pathology of a Tertiary Care Hospital of Delhi over a period of 1 year where all the cases with histopathological diagnosis of nasal TB were reviewed. Patients’ clinical details, investigations and treatment details along with follow‑up were obtained from the medical records section. For each case, routine hematoxylin and eosin stain were studied along with Ziehl–Neelson staining. Results: A total of four patients were diagnosed with nasal TB histopathologically. Patients’ age ranged from 5 to 34 with an equal male to female ratio. All patients were immunocompetent. Primary nasal TB was seen in all of the four cases. None of the cases, it was clinically suspected, and histopathology was the mainstay of diagnosis. All the cases were treated with antituberculous treatment and showed considerable improvement. Conclusions: Although nasal TB is rare, it should be considered in the differential diagnosis of chronic nasal symptoms and granulomatous lesions of the nose. Histopathology plays an important role in the diagnosis of these clinically unsuspecting cases of nasal TB.

SACROCOCCYGEAL TERATOMA : A RARE ENTITY

2021 ◽  
pp. 71-72
Author(s):  
Manisha Albal ◽  
Shriniket Sawarkar
Keyword(s):  
Clinical Presentation ◽  
Neonatal Period ◽  
Tertiary Care ◽  
Primitive Streak ◽  
Sacrococcygeal Teratoma ◽  
Care Hospital ◽  
Female Ratio ◽  
Sacrococcygeal Region ◽  
Paediatric Age ◽  
Male To Female

Teratomas are composed of tissues derived from ectoderm, mesoderm, and endoderm. Sacrococcygeal teratomas are developed from the totipotential cells of primitive knot which is a remnant of the primitive streak in the coccygeal region. With the incidence of 1/35000–1/40000 live birth, sacrococcygeal teratoma is considered as the most common germ cell tumor in the neonatal period and infancy. Sacrococcygeal teratoma shows female preponderance with male to female ratio 1:4 . AIMS AND OBJECTIVES: To study clinical presentation and management of sacrocoocygeal teratoma in paediatric age group. CASE REPORT: A seven year old child presented to our tertiary care hospital with a swelling of size 20 x 10 cm in sacrococcygeal region Which was initially smaller in size about 6 X 3cm and have gradually progressed to the present size swelling was soft to rm in consistency, patient was subject to MRI pelvis which was suggestive of solid cystic swelling in sacrococcygeal region of size 20 X 15 cm with maintained fat planes with rectum and adjacent organs. Patients was subjected to surgery in which the teratoma was removed of size 20 x 15 cm along with coccygectomy was done intraoperatively there was no involvement of rectum or other organs or pelvic walls. Child recovered well post operatively and the histopathological report conrmed the diagnosis of sacrococcygeal teratomawith solid cytic compoments.

COMPARISON OF CLINICO-SOCIAL PROFILE OF PULMONARY AND EXTRA PULMONARY TUBERCULOSIS IN TERTIARY CARE HOSPITAL IN A RURALAREA: A RETROSPECTIVE STUDY

2021 ◽  
pp. 70-72
Author(s):  
Gaurav Santosh Nemade ◽  
Sumit Nitin Dhus ◽  
Arushi Ramesh Shetty ◽  
Neha Dhananjay Firake
Keyword(s):  
Tertiary Care ◽  
Care Hospital ◽  
Female Ratio ◽  
Extra Pulmonary Tuberculosis ◽  
Younger Age ◽  
Tobacco Addiction ◽  
History Of ◽  
Early Case ◽  
Male To Female ◽  
Clinical Characteristic

BACKGROUND AND OBJECTIVES: The burden of tuberculosis (TB) in India is the highest accounting for 26% of the global incidence. A total of 1.4 million people died from TB in 2019 (including 208 000 people with HIV). India accounts for a fourth of the global burden of TB and 29% of global mortality. Therefore, we carried out this study to compare demographic, lifestyle and clinical characteristic between pulmonary TB (PTB) and extrapulmonary TB (EPTB). MATERIALS AND METHODOLOGY:Aretrospective analysis was carried of 348 patients diagnosed in DOTS centre, Pravara Rural Hospital, Loni. Characteristics of demographic and clinical characteristics were obtained from medical case records. RESULTS:Among the 348 cases, 71.3% were PTB and 28.7% were EPTB including, pleural (36%), meningeal (27%) and lymphatic (20%) cases. The male to female ratio in PTB and EPTB are 1.99 and 1.22 respectively. EPTB was more common at younger age (<25 years). Tobacco addiction (10.9%), diabetes mellitus (4.03%), HIV positivity (12.1%) and history of contact with Tb patients (17.7%) were more likely to be associated with PTB. CONCLUSION:Increased awareness of the risk factors may facilitate early case nding and better management outcomes for these patients.

scholarly journals Dengue Fever : Study of 100 Cases in a Tertiary Care Hospital in Dhaka City

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 3-7
Author(s):  
A H M Karnal ◽  
K H Mollah ◽  
A Begum ◽  
K Khoda ◽  
S Tanzeem ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Tertiary Care ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Care Hospital ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Body Ache

Dengue is a rapidly spreading mosquito-borne viral disease worldwide. The endemicity in Bangladesh is also increasing gradually. The study was a prospective observational one, documented the presenting features and outcome of management. It was carried out in Department of Medicine in Holy Family Red Crescent Medical College Hospital, Dhaka from June 2013 to December 2013. Total 100 admitted cases of both sera positive and sera-negative were included in this study. Detailed history was taken, clinical examination and relevant investigations were done. Out of 100 patients 54 (54%) were male and 46 (46%) were female. So male to female ratio was 1.7:1. The age of the patients ranged from 12-75 years. Among them 20-40 years age group was highest 63%. Patients of higher socio-economic group were (69%) more affected. Out of 100 cases 54 had classical dengue fever (DF), 46 had dengue hemorrhagic fever (DHF). Antibody was positive in 81% cases. All patients presented with high fever, headache in 90%, retro-orbital pain in 45%, body ache in 56%, and backache in 48%. Leucopenia found in 60, platelet count <100x1091L was in 57, HCT- normal 17, <20% rise in 48%, ?20% rise in 28%. With proper management all patients were recovered.

scholarly journals Clinical Spectrum and Neuroimaging Changes in Neurodegenerative Disorder-Experiences in Tertiary Care Hospital of Bangladesh

2021 ◽  
Vol 2 (6) ◽  
pp. 10-14
Author(s):  
Gopen Kumar Kundu ◽  
Rumana Islam ◽  
Noor E-Sabah ◽  
ABM Mukib
Keyword(s):  
Neurodegenerative Diseases ◽  
Tertiary Care Hospital ◽  
Neurodegenerative Disorder ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Care Hospital ◽  
Female Ratio ◽  
History Of ◽  
The Mean ◽  
Male To Female

Neurodegenerative diseases (NDD) are a heterogeneous group of disorders characterized by progressive loss of previously acquired skills that are of varied etiology, clinical manifestations, and natural course. There is a paucity of data on clinical profile of neurodegenerative diseases in our population. We conducted a retrospective study with 68 diagnosed cases of NDD at a tertiary care hospital in Bangladesh. Among them, more than one-third of children were in 1-5 years age group. The mean age was 10.2±3.1 year and male to female ratio was 2:1. Fifty percent of cases had a history of consanguineous parents. Leukodystrophy was most common (30.88%) among NDDs, followed by Wilson disease (26.47), SSPE (22.1%), and Degenerative Ataxia (20.59%). Motor skill regression was the most common presentation (97%), followed by speech regression in 91% and Gait disorder in 83% of children. Seizure was presenting features in 24% of children. Neuroimaging abnormalities were found in 80.88% NDD cases. Among them white matter hyper intensity in 29.41%, cerabeller atrophy in 13.25 %, and cerebral atropy in 11.76% of children. Eye changes were found in about two-thirds (69.12%) of cases of NDD. Among them, optic atrophy was found in 29.41%, and KF rings in 25.00% of cases.

CLINICO-MYCOLOGICAL PROFILE OF DERMATOPHYTOSIS AND DERMATOMYCOSIS AMONG PATIENTS ATTENDING OUTPATIENT DEPARTMENT IN A TERTIARY CARE HOSPITAL.

2021 ◽  
pp. 1-3
Author(s):  
Kapaganty V Chakradhar ◽  
Dilruba Begum ◽  
Ruby Devi N ◽  
Raya Roja
Keyword(s):  
Tertiary Care ◽  
Fungal Growth ◽  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Microsporum Gypseum ◽  
Care Hospital ◽  
Female Ratio ◽  
Hair Samples ◽  
Mycological Examination ◽  
Male To Female

This study was conducted to determine the common isolates causing dermatophytosis and other fungi causing dermatomycosis in patients presenting with skin lesions with or without involvement of hair and nails. A total of 75 patients were included in the study with 86 distinctive clinical lesions, of which Tinea corporis (46.7%,) was the most predominant followed by T. cruris (22.7%), T. unguium (14.7%) with a male to female ratio of 1.3:1. KOH mounts were made from samples and examined for fungal elements and samples were sent to Microbiology laboratory for culture, and identication among them 77.3% were skin scrapings alone and 14.7% were nail clippings along with skin scrapings and 8% were hair samples along with skin scrapings. Most common isolate was Trichophyton rubrum (40%) followed by Trichophyton mentagrophytes (17.3%), Trichophyton tonsurans (9.3%), Microsporum gypseum (4%) and no fungal growth was found in 17.3% of the samples. The study signies the importance of mycological examination in the diagnosis of dermatophytosis.

scholarly journals An Observational Study of Stroke and its Outcomes in a Tertiary Care Hospital

2020 ◽  
Author(s):  
Amruth Gujjar ◽  
Rekha Walwekar ◽  
AN Dattatri
Keyword(s):  
Drug Therapy ◽  
Clinical Presentation ◽  
Tertiary Care ◽  
Clinical History ◽  
Haemorrhagic Stroke ◽  
Developed Countries ◽  
P Value ◽  
Care Hospital ◽  
Case Record

Introduction: Incidence of stroke is higher in developing countries than in developed countries. India shows prevalence of Cerebrovascular Disease (CVD) in the range of 52 to 843/100,000 population. Stroke causes 9% deaths around the world. The basic principle of managing stroke includes making an accurate diagnosis, choosing the effective drugs and dose for the stroke type. Aim: To analyse the outcomes of pharmacotherapy of stroke based on characteristics and clinical presentation of patients admitted to hospital and to know the adverse effect of drugs used. Materials and Methods: This cohort study was conducted with Department of Medicine and Neurology at Karnataka Institute of Medical Sciences, Hubballi from January 2015 to December 2015. After clearance from Institutional Ethics Committee, 162 cases were selected based on the inclusion and exclusion criteria. The clinical history, in examination modified Rankin score (mRS) at admission, discharge and on follow-up were recorded. The criteria for selecting the drugs, frequency, dosing, duration and change in drug therapy were recorded. The efficacy of drug therapy was assessed by clinical improvement. The adverse events were assessed and recorded. The patients were followed-up at three and six months. The data were entered after defining the variables in SPSS (version 16) from case record form. Descriptive statistics were used to summarise baseline data. Results: Of the 162 patients, 155 completed the six months follow-up. The median age of patients was 60 years for ischaemic and 55 years for haemorrhagic stroke. More males were admitted with strokes {108 (69.67%)} compared to females {47 (30.32%)}; 130 (83.87%) patients had ischaemic strokes, 16 (10.30%) haemorrhagic stroke {15 (9.67%) were intracerebral haemorrhage + 1 (0.63 %) patient had a subarachnoid haemorrhage}, 9 (5.8%) had Transient Ischaemic Attack (TIA). The modified Rankin score calculated for the patients was statistically significant between admission and discharge (1.29, p-value 0.0035), and that between three months and six months (0.9, p-value 0.003) of follow-up.Total 93% of 121 patients with ischaemic stroke received antiplatelet therapy. Amlodipine was the most commonly prescribed antihypertensive. Conclusion: Pharmacotherapy of stroke in the study was evidence-based and satisfactory. However, patients showed reduced compliance to all medications. Clinical presentation and type of stroke were important predictors of morbidity and mortality at the end of six months.

scholarly journals Clinico-pathological and demographic profile of patients with carcinoma stomach: a tertiary care experience

2019 ◽  
Vol 6 (6) ◽  
pp. 2145
Author(s):  
Shabir Ahmad Mir ◽  
Mir Intikhab ◽  
Hanief Mohamed Dar ◽  
Mumtazdin Wani
Keyword(s):  
Gastric Cancer ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Female Ratio ◽  
Demographic Profile ◽  
History Of ◽  
Carcinoma Stomach ◽  
Gastric Malignancy

Background: Gastric cancer is a common malignancy all over the world, and our valley is not an exception. Under this background, we conducted the present study at our tertiary care hospital to look into the clinico-demographic profile of this disease.  Aim was to determine the clinico-pathological and demographic profile of patients with carcinoma stomach attending to our tertiary care hospital.Methods: This prospective study was conducted in unit-II of department of general surgery in Shri Maharaja Harisingh hospital Srinagar, over a period of 5.5 years from July 2012 to December 2017. All patients with histopathological diagnosis of gastric malignancy were included and analysed.Results: Male to female ratio was 1.4:1 with mean age of 63.23 years. The most common histopathological type of gastric malignancy was adenocarcinoma (85.84%) followed by lymphoma. The most common location of the gastric cancer was distal third of the stomach. Fifty-seven patients (50.4%) were offered definitive surgery and 21(18.58%) were managed by palliative surgery. Out of 113 patients, 87 patients (76.9%) had present or past history of smoking. The most common presentation in our study was dyspepsia.Conclusions: Profile of gastric carcinoma in our institution is not in wide variance with that of other studies. A significant proportion of patients presented with an advanced or unresectable disease because of the delay in proper screening. All patients with history of dyspepsia (age >50 years) and anemia should undergo screening upper gastrointestinal (UGI) endoscopy at the earliest, so that we can detect the lesion at the initial stage.

scholarly journals Spectrum of Different Spinal Disorders Presenting to Neurosurgical Department of Public Sector Tertiary Care Hospitals of Peshawar

2019 ◽  
Vol 23 (4) ◽  
Author(s):  
ADNAN AHMED ◽  
MOHAMMAD ISHAQ ◽  
MUMTAZ ALI ◽  
MUSAWER KHAN ◽  
SOHAIL AHMAD ◽  
...  
Keyword(s):  
Public Sector ◽  
Tertiary Care ◽  
Neurosurgical Department ◽  
Female Ratio ◽  
Spinal Disorders ◽  
And Gender ◽  
Age Range ◽  
Tertiary Care Hospitals ◽  
Male To Female

Objectives: To assess the spectrum of different spinal disorders presenting to the Neurosurgical department of public sector tertiary care hospitals of Peshawar.Materials and Methods: This was a retrospective study carried out in the Neurosurgery departments of two public sector tertiary care hospitals in district Peshawar from January 2012 to December 2018. Our inclusion criteria comprised of all those patients who were having spinal abnormalities irrespective of age and gender, admitted either via emergency or OPD. We excluded those patients who were dead on arrival or whose data was lacking including those who did not do their follow up and those who were not given consent for the study.Results: Out of total 5,579 patients, male to female ratio was 1:1.7. The age range was from 6 days to 78 years. Elective cases were 63.61% (n = 3,549) and emergency were 36.37% (n = 2,030). TSCI were 35.01% (n = 1,953) and NTSCI were 3,626 (n = 64.99%). Out of all patients, 91.03% (n = 5,079) were treated surgically. About 79% (n = 4,406) had a good outcome.Conclusion: We collected data and made a survey of the spectrum of different spinal abnormalities resulting from various etiologies focused over the last 6 years. We found a variety of cases presenting to our departments of neurosurgery. Non traumatic spinal injuries are more frequent as compared to traumatic ones.

DIFFERENTIAL DIAGNOSIS OF NASAL MASS IN A TERTIARY CARE HOSPITAL OF JHARKHAND

2021 ◽  
pp. 6-7
Author(s):  
Md Raihan ◽  
Suraj Sinha ◽  
Sona Pathak ◽  
Sunil Kumar Mahto
Keyword(s):  
Differential Diagnosis ◽  
Tertiary Care ◽  
Age Groups ◽  
Nasal Discharge ◽  
Care Hospital ◽  
Elderly Age ◽  
Female Ratio ◽  
Nasal Mass ◽  
Abnormal Growth ◽  
Male To Female

Background: Nasal mass is abnormal growth in the nose, which may be benign or malignant and may be unilateral or bilateral. Nasal masses in most patients present with complaints of nasal obstruction. It may cause nasal discharge, epistaxis and anosmia. A nasal mass can have various differential diagnosis which this study aims to explore. Material and Methods: A retrospective study of histopathologically diagnosed cases of nasal masses for a period 3 years from January 2017 to December 2019. Results: Out of 95 patients 55 (57.89%) male and 40 (42.10%) female, male to female ratio is 1.37:1 with a mean age of 23 years (range= 2-63 years). Most of the cases 94(98.95%) were non-malignant and only 1(1.05%) was malignant (Adenoid cystic carcinoma). Malignancy of sinonasal tract is rare. Conclusion: With this study we can say that nasal masses are more common in males than females, adults age groups affected more than elderly age groups. It is also inferred that most of the nasal masses are benign in nature and very few cases are malignant in nature.

scholarly journals Spectrum of Haematological Abnormalities in Patients of Multiple Myeloma

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kiran Aamir ◽  
Muhammad Hanif ◽  
Hina Abbas ◽  
Aamir Ramzan
Keyword(s):  
Multiple Myeloma ◽  
Plasma Cells ◽  
Tertiary Care ◽  
Biological Behavior ◽  
Plasma Cell Dyscrasia ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Female Ratio ◽  
Lytic Lesions ◽  
Male To Female

Background: Multiple myeloma is plasma cell dyscrasia characterized by uncontrolled proliferation of plasma cells and adistinctive biological behavior. It is an uncommon hematological malignancy which primarily affects older individuals.Objective: To determine clinico-hematological profile of Multiple Myeloma patients.Material and Methods: It is a retrospective study conducted at a tertiary care hospital for a period of 6 month in which 55 patientsdiagnosed as Multiple myeloma were enrolled. Data of 55 cases of multiple myeloma was analyzed.Results: Fifty five confirmed cases of MM were identified. There were 44 male and 11 female with a male to female ratio of 2:1. Thefrequency of multiple myeloma was high in patients with age 60-69 years. The median age of all patients was 56yrs (range 34-75).Anemia was present in 96.3% of patients 51% showed thrombocytopenia and 15% showed leucopenia. 91% of patients had ESRvalues above 80mm/hr. Serum of 93% patients showed M.band in SPE. Bone marrow of 45.4% patients had 11-20% plasma cells,marrow of 20% of patients contain 21-60% cells while that of 34.5% patients contain > 60% plasma cells. It was observed thatsome of those patients with plasma cells >60% showed severe anemia, severe thrombocytopenia and severe leucopenia.Radiographic examination showed lytic lesions in all patientsConclusions: Our analysis shows that clinico-pathological features of multiple myeloma patients in Pakistan are comparable topublished data.

Sign in / Sign up

Export Citation Format

Share Document