In vitro Antibacterial and Anticancer Potential of CeO2 Nanoparticles Prepared by Co-precipitation and Green Synthesis Method

2017 ◽  
Vol 02 (02) ◽  
Author(s):  
D. S Parvathya ◽  
Venkatramanb BR
Keyword(s):  
Green Synthesis ◽  
Synthesis Method ◽  
Ceo2 Nanoparticles ◽  
Co Precipitation

scholarly journals Green synthesis of silver, iron and gold nanoparticles of lycopene extracted from tomato: their characterization and cytotoxicity against COLO320DM, HT29 and Hella cell

2021 ◽  
Vol 32 (2) ◽  
Author(s):  
Kiran P. Shejawal ◽  
Dheeraj S. Randive ◽  
Somnath D. Bhinge ◽  
Mangesh A. Bhutkar ◽  
Sachin S. Todkar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Gold Nanoparticles ◽  
Green Synthesis ◽  
Color Change ◽  
Synthesis Method ◽  
Vitro Assay ◽  
Prepared Nanoparticles ◽  
Cytotoxicity Studies ◽  
Ht 29

AbstractOur study aimed at development of Silver, Iron and Gold nanoparticles of Lycopene isolated from tomato by using green synthesis technique and to evaluate its anticancer potential against colorectal and cervical cancer. Lycopene was extracted by benzene extraction method and the silver, iron and gold nanoparticles were developed by green synthesis method. 1% aqueous extract of isolated Lycopene was mixed with 1% solutions of AgNO3, FeCl3 and HAuCl4 solutions and incubated at ambient temperature for 3–4 h separately and observed for the color change which is an indicative of formation of the nanoparticles. The prepared nanoparticles were characterized by FTIR, SEM, XRD analysis and evaluated for their antimicrobial potential. The cytotoxicity studies were carried out by in vitro assay like MTT, SRB and Tryphan blue method against Colo 320 DM, HT 29, and Hella. SEM showed nanosized particles of 50–100 nm range, whereas no antimicrobial activity was exhibited by the prepared nanoparticles. In MTT assay the LyAgNP showed maximum 41.41 ± 0.4124% inhibition against COLO320DM, whereas LyGNP exhibited 41.47 ± 0.4469% inhibition against HT 29 and LyAgNP showed 40.9 ± 0.6908% inhibition against Hella cells. In SRB assay LyAgNP showed maximum 82.68 ± 1.1798% inhibition against COLO320DM, whereas LyGNP exhibited maximum 91.21 ± 0.2372% inhibition against HT29 and 87.98 ± 0.5878% inhibition against Hella cells. In tryphan blue assay against COLO320DM, HT29 and Hella cells, the maximum inhibition exhibited by the prepared nanoparticles were observed as LyGNP 83.45 ± 0.4694%, LyAgNP 88.05 ± 0.1870% and LyAgNP65.47 ± 0.4766%. We conclude that the developed nanoparticles of Lycopene exhibited potential anticancer activity against Colorectal and cervical cancer cell as compared with pure Lycopene.

Synthesis and Biological Evaluation of Amoxicillin Loaded Hybrid Material Composite Spheres Against Methicillin-Resistant Staphylococcus aureus

2020 ◽  
Vol 21 ◽  
Author(s):  
Muhammad Arfat Yameen ◽  
Amir Zeb ◽  
Raza E Mustafa ◽  
Sana Mushtaq ◽  
Nargis Aman ◽  
...  
Keyword(s):  
Mtt Assay ◽  
Hybrid Material ◽  
Ag Nanoparticles ◽  
Hybrid Composite ◽  
Synthesis Method ◽  
Biological Evaluation ◽  
Vitro Assay ◽  
Cytotoxicity Studies ◽  
Material Composite

Background: Incoherent use of antibiotics has led toward resistance in MRSA, which is becoming multidrugresistant with high rate of virulence in the community and hospital settings. Objective: Synergistic anti-MRSA activity was investigated in this study for hybrid material composite spheres of amoxicillin, Ag nanoparticles and chitosan which were prepared by one-step synthesis method and various characterizations were performed. Methods: Antimicrobial-susceptibility assay on MRSA was achieved by disc diffusion and agar dilution techniques while agar well diffusion was used for hybrid composite spheres. The in vitro and cytotoxicity studies was done by skin abrasion mouse model and MTT assay on RD cell respectively. Results: All isolates were resistant with the tested antibiotics except vancomycin. MIC against MRSA showed high resistance with amoxicillin from 4 to 128 mg L-1. The mean diameter of chitosan spheres and Ag nanoparticles was 02 mm and 277 nm respectively. Morphology of spheres was uneven, varied, porous and irregular in SEM and Ag nanoparticles presence and formation was also seen in micrograph. No substantial interface among drug, nanoparticles and polymer was found in XRD and IR showed characteristic peaks of all compound in the formulation. The in vitro assay showed augmented anti-MRSA activity with amoxicillin loaded hybrid composite spheres (22-29 mm). A significant reduction in microbial burden (~6.5 log10 CFU ml-1) was seen in vivo with loaded hybrid composite spheres formulation. The MTT assay indicated no potential cytotoxicity with hybrid composite spheres. Conclusion: Synergistic effect, amoxicillin, new hybrid formulation, anti-MRSA activity, composite spheres. nanoparticles.

New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies

2018 ◽  
Vol 14 (5) ◽  
pp. 536-548
Author(s):  
Sahar Yousuf ◽  
Khalid M. Khan ◽  
Uzma Salar ◽  
Almas Jabeen ◽  
Shakil Ahmed ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Structural Characterization ◽  
In Vitro Studies ◽  
Environment Friendly

Recent Advances and Need of Green Synthesis in Two-Dimensional Materials for Energy Conversion and Storage Applications

2021 ◽  
Vol 16 ◽  
Author(s):  
Joice Sophia Ponraj ◽  
Muniraj Vignesh Narayanan ◽  
Ranjith Kumar Dharman ◽  
Valanarasu Santiyagu ◽  
Ramalingam Gopal ◽  
...  
Keyword(s):  
Energy Storage ◽  
Green Synthesis ◽  
2D Materials ◽  
Synthesis Method ◽  
Energy Storage And Conversion ◽  
Two Dimensional ◽  
Severe Problem ◽  
Energy Conversion And Storage ◽  
Energy Application ◽  
The Impact

: Increasing energy crisis across the globe requires immediate solutions. Two-dimensional (2D) materials are in great significance because of its application in energy storage and conversion devices but the production process significantly impacts the environment thereby posing a severe problem in the field of pollution control. Green synthesis method provides an eminent way of reduction in pollutants. This article reviews the importance of green synthesis in the energy application sector. The focus of 2D materials like graphene, MoS2, VS2 in energy storage and conversion devices are emphasized based on supporting recent reports. The emerging Li-ion batteries are widely reviewed along with their promising alternatives like Zn, Na, Mg batteries and are featured in detail. The impact of green methods in the energy application field are outlined. Moreover, future outlook in the energy sector is envisioned by proposing an increase in 2D elemental materials research.

scholarly journals Green Synthesis of CeO2 Nanoparticles from the Abelmoschus esculentus Extract: Evaluation of Antioxidant, Anticancer, Antibacterial, and Wound-Healing Activities

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4659
Author(s):  
Hafiz Ejaz Ahmed ◽  
Yasir Iqbal ◽  
Muhammad Hammad Aziz ◽  
Muhammad Atif ◽  
Zahida Batool ◽  
...  
Keyword(s):  
Wound Healing ◽  
Metal Oxide Nanoparticles ◽  
In Vitro Cytotoxicity ◽  
Ceo2 Nanoparticles ◽  
Abelmoschus Esculentus ◽  
Oxide Nanoparticles ◽  
Dependent Manner ◽  
Hydrogel Membrane ◽  
Cancerous Cells

Metal oxide nanoparticles synthesized by the biological method represent the most recent research in nanotechnology. This study reports the rapid and ecofriendly approach for the synthesis of CeO2 nanoparticles mediated using the Abelmoschus esculentus extract. The medicinal plant extract acts as both a reducing and stabilizing agent. The characterization of CeO2 NPs was performed by scanning electron microscopy (SEM), X-ray diffraction (XRD), ultraviolet-visible spectroscopy (UV-Vis), and Fourier transform infrared spectroscopy (FTIR). The in vitro cytotoxicity of green synthesized CeO2 was assessed against cervical cancerous cells (HeLa). The exposure of CeO2 to HeLa cells at 10–125 µg/mL caused a loss in cellular viability against cervical cancerous cells in a dose-dependent manner. The antibacterial activity of the CeO2 was assessed against S. aureus and K. pneumonia. A significant improvement in wound-healing progression was observed when cerium oxide nanoparticles were incorporated into the chitosan hydrogel membrane as a wound dressing.

scholarly journals Green Synthesis of Copper Nanoparticles Using Cotton

Polymers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 1906
Author(s):  
Marissa Pérez-Alvarez ◽  
Gregorio Cadenas-Pliego ◽  
Odilia Pérez-Camacho ◽  
Víctor E. Comparán-Padilla ◽  
Christian J. Cabello-Alvarado ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Copper Nanoparticles ◽  
Uv Spectroscopy ◽  
Synthesis Method ◽  
Crystallinity Index ◽  
Reaction Conditions ◽  
New Synthesis ◽  
Water As Solvent ◽  
Characterization Studies ◽  
Xrd Patterns

Copper nanoparticles (CuNP) were obtained by a green synthesis method using cotton textile fibers and water as solvent, avoiding the use of toxic reducing agents. The new synthesis method is environmentally friendly, inexpensive, and can be implemented on a larger scale. This method showed the cellulose capacity as a reducing and stabilizing agent for synthetizing Cellulose–Copper nanoparticles (CCuNP). Nanocomposites based on CCuNP were characterized by XRD, TGA, FTIR and DSC. Functional groups present in the CCuNP were identified by FTIR analysis, and XRD patterns disclosed that nanoparticles correspond to pure metallic Cu°, and their sizes are at a range of 13–35 nm. Results demonstrated that CuNPs produced by the new method were homogeneously distributed on the entire surface of the textile fiber, obtaining CCuNP nanocomposites with different copper wt%. Thus, CuNPs obtained by this method are very stable to oxidation and can be stored for months. Characterization studies disclose that the cellulose crystallinity index (CI) is modified in relation to the reaction conditions, and its chemical structure is destroyed when nanocomposites with high copper contents are synthesized. The formation of CuO nanoparticles was confirmed as a by-product, through UV spectroscopy, in the absorbance range of 300–350 nm.

scholarly journals Green synthesis and characterization of hexaferrite strontium-perovskite strontium photocatalyst nanocomposites

2020 ◽  
Vol 43 (1) ◽  
pp. 26-42 ◽  
Author(s):  
Zahra Hajian Karahroudi ◽  
Kambiz Hedayati ◽  
Mojtaba Goodarzi
Keyword(s):  
Magnetic Properties ◽  
Green Synthesis ◽  
Sol Gel ◽  
Synthesis Method ◽  
Combustion Method ◽  
Lemon Juice ◽  
X Ray Diffraction ◽  
X Ray ◽  
Auto Combustion

AbstractThis study presents a preparation of SrFe12O19– SrTiO3 nanocomposite synthesis via the green auto-combustion method. At first, SrFe12O19 nanoparticles were synthesized as a core and then, SrTiO3 nanoparticles were prepared as a shell for it to manufacture SrFe12O19–SrTiO3 nanocomposite. A novel sol-gel auto-combustion green synthesis method has been used with lemon juice as a capping agent. The prepared SrFe12O19–SrTiO3 nanocomposites were characterized by using several techniques to characterize their structural, morphological and magnetic properties. The crystal structures of the nanocomposite were investigated via X-ray diffraction (XRD). The morphology of SrFe12O19– SrTiO3 nanocomposite was studied by using a scanning electron microscope (SEM). The elemental composition of the materials was analyzed by an energy-dispersive X-ray (EDX). Magnetic properties and hysteresis loop of nanopowder were characterized via vibrating sample magnetometer (VSM) in the room temperature. Fourier transform infrared spectroscopy (FTIR) spectra of the samples showed the molecular bands of nanoparticles. Also, the photocatalytic behavior of nanocomposites has been checked by the degradation of azo dyes under irradiation of ultraviolet light.

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