scholarly journals MANAGEMENT OF GARBHODAKAVRIDDHI W.S.R. TO POLYHYDRAMNIOS THROUGH AYURVEDA - A CASE REPORT

2021 ◽  
Vol 9 (7) ◽  
pp. 1564-1570
Author(s):  
Divya Deepak Patil ◽  
Sonu Sonu ◽  
Vipin Tanwar ◽  
Mukesh Chaudhari

Introduction: Polyhydramnios is a relatively common clinical presentation in pregnancy with a varying incidence of 1-2% of cases. There is yet no data suggestive of improvement in perinatal outcome with antenatal fetal surveil- lance. Since it is associated with significant perinatal morbidity and mortality, fixing up a standard treatment pro- tocol for its management is needed. Case Description: A 28-year-old female patient consulted Prasutitantra and Streeroga OPD, NIA Hospital, Jaipur complaining of difficulty in breathing, palpitations, hyperacidity for 15 days with 8 months of amenorrhea. Diagnosis: Based on abdominal examination and radiological findings, the case was diagnosed with polyhydramnios. On the correlation of symptoms as stated by Acharya Sushruta, Ayurvedic diag- nosis of Garbhavriddhi was made. Intervention: As in the management of garbhavriddhi, practices involving appropriate samshodhana (purifying) and sanshamana (suppressive) yet kshaya-avirodhi karma (not causing loss of dosha or dhatu below optimal range) are prescribed. Hence, an intervention of Ksheerabasti with Punar- navashtaka Kwatha was done along with the oral medication in the present study. Outcome: USG done after 7 days of treatment course showed significant correction in AFI as well relief from clinical symptoms. Conclusion: This case illustrates that Polyhydramnios can be managed effectively and safely with Punarnavashtaka kwatha ksheera basti. Mutrajanana, Srotoshodhana, Kledapachana, and Shothaghna are the main actions essential in its manage- ment. Keywords: Garbhavriddhi, Polyhydramnios, Punarnavashtaka kwatha, Ksheera basti

Author(s):  
Paolo Biagi ◽  
Luigi Abate ◽  
Carmine Mellone ◽  
Stefania Salvadori ◽  
Andrea Peccetti ◽  
...  

BackgroundEosinophilic gastroenteritis (EoG) is a rare disease of unknown etiology characterized by patchy or diffuse eosinophilic infiltration of the gastrointestinal tract wall. As clinical presentation and endoscopic/ radiological findings are nonspecific, diagnosis may only be ascertained by histologic findings.Clinical case This article presents a case of EoG with associated colonic involvement but without peripheral eosinophilia. Although no allergy could be demonstrated, the clinical symptoms and histologic pattern of diffuse eosinophilic mucosal infiltration disappeared after steroid therapy, as discovered by a careful endoscopic follow-up.Discussion Current concepts of this complex disorder and a review of the literature are presented.


2020 ◽  
Vol 1 (2) ◽  
pp. 110-112
Author(s):  
Perdana Aditya Rahman ◽  
Ahmad Ahmad Bayhaqi Nasir Aslam

Chest pain is a common clinical presentation in daily practice. Musculoskeletal origin is a rare etiology of chest pain, compared to a cardiorespiratory problem and often underrecognized. Fork-rib or bifid-rib is a rare anomaly which uncommonly present with clinical symptoms since in most cases fork-rib incidentally found during cadaveric dissection. Here we report a 27 years old man presenting with chest pain and radiographic examination showing bifid rib of the fifth left rib, without any abnormalities from physical examination and electrocardiography. The patient treated with intravenous painkiller and anticonvulsants. Fork-rib should be considered as a differential diagnosis for chest pain of musculoskeletal origin especially in young adults or chest pain precede with minor trauma.


1981 ◽  
Vol 95 (5) ◽  
pp. 493-502 ◽  
Author(s):  
S. L. Sellars ◽  
J. C. De Villiers

SummaryMucocoeles, mucopyocoeles and empyemas of the sphenoid sinus are rare, but potentially dangerous. Their occurrence is accompanied by a multitude of clinical symptoms and signs, which confuse the diagnosis and may lead to its mismanagement. The treatment of this condition is surgical and in its early states essentially simple.At Groote Schuur Hospital over a 6-year period (1972–1977) 6 patients with mucocoeles, mucopyocoeles or abscesses of the sphenoid sinuses have been seen. Their clinical presentation, radiological findings and surgical treatment are described and discussed. Correctly managed this condition should completely resolve; however, there is a mortality associated with delay or misdiagnosis.


Author(s):  
Himang Jharaik ◽  
Bishan Dhiman ◽  
S. K. Verma ◽  
Aditi Sharma

Background: Antepartum haemorrhage, a life-threatening event, is defined as bleeding per vaginum occurring after the fetus has reached the period of viability, considered to be 20 weeks in developed countries and 28 weeks in countries with low resource settings. We evaluated the consequences of antepartum haemorrhage, their maternal and perinatal outcome so as to outline the proper management of patient in order to improve both maternal and perinatal morbidity and mortality.Methods: This one-year prospective study totaled 133 cases of APH fulfilling the inclusion criteria were studied. Data was recorded on the MS excel sheet for further analysis and processing.Results: Total 6693 deliveries were conducted out of which 133 presented as APH and incidence of APH was found out to be 1.98%. Placenta previa was most common. APH was commonly associated with multigravida and most cases were in age group of 26-30 years. Most of the PP and abruption cases were admitted at 34-37 weeks and 31-33 weeks respectively. High risk factors included previous LSCS and D and C, hypertension, multiple pregnancies and malpresentations. Most of the patients underwent preterm LSCS. Most fetal complications were due to prematurity. 58.6% patients were transfused blood. Overall perinatal mortality was 20.1% and maternal mortality was zero.Conclusions: Early diagnoses, timely referrals and transfusion facilities along with trained team of doctors with well-equipped ICU facility goes a long way in avoiding APH related maternak and fetal complications.


2003 ◽  
Vol 17 (3) ◽  
pp. 267-277 ◽  
Author(s):  
Scott Temple

“Multiple chemical sensitivities” has become an increasingly common clinical presentation to physicians, though it is infrequently seen by psychotherapists. This case report describes a 61-year-old woman who presents with a long history of chemical sensitivities, that led to a somatization disorder with debilitating agoraphobia, depression, and marital problems. Features of a variety of anxiety disorders are present, as are metacognitions that required an unusual case conceptualization. A cognitive therapy case conceptualization and treatment are described, which address the highly idiosyncratic clinical presentation of this patient.


2010 ◽  
Vol 65 (2) ◽  
pp. 167-171 ◽  
Author(s):  
S. Yanny ◽  
A.P. Toms ◽  
D. MacIver ◽  
T. Barker ◽  
A. Wilson

2021 ◽  
Vol 10 (15) ◽  
pp. 3230
Author(s):  
Jun Nishio ◽  
Shizuhide Nakayama ◽  
Kazuki Nabeshima ◽  
Takuaki Yamamoto

Dedifferentiated liposarcoma (DDL) is defined as the transition from well-differentiated liposarcoma (WDL)/atypical lipomatous tumor (ALT) to non-lipogenic sarcoma, which arises mostly in the retroperitoneum and deep soft tissue of proximal extremities. It is characterized by a supernumerary ring and giant marker chromosomes, both of which contain amplified sequences of 12q13-15 including murinedouble minute 2 (MDM2) and cyclin-dependent kinase 4 (CDK4) cell cycle oncogenes. Detection of MDM2 (and/or CDK4) amplification serves to distinguish DDL from other undifferentiated sarcomas. Recently, CTDSP1/2-DNM3OS fusion genes have been identified in a subset of DDL. However, the genetic events associated with dedifferentiation of WDL/ALT remain to be clarified. The standard treatment for localized DDL is surgery, with or without radiotherapy. In advanced disease, the standard first-line therapy is an anthracycline-based regimen, with either single-agent anthracycline or anthracycline in combination with the alkylating agent ifosfamide. Unfortunately, this regimen has not necessarily led to a satisfactory clinical outcome. Recent advances in the understanding of the pathogenesis of DDL may allow for the development of more-effective innovative therapeutic strategies. This review provides an overview of the current knowledge on the clinical presentation, pathogenesis, histopathology and treatment of DDL.


Author(s):  
Ghafar-Ali Mahmoudi ◽  
Maryam Ahadi ◽  
Ali Fouladvand ◽  
Bareza Rezaei ◽  
Zahra Bodagh ◽  
...  

Background: Antivenom is a gold-standard treatment for snakebite envenoming. However, adverse reactions to snake antivenom are common in many parts. Objective: The aim of this study was to evaluate the allergic reactions following intravenous administration of antivenom sera. Methods: This was retrospective study, conducted snakebites patients referred to the Rahimi Hospital in Khorramabad. The files of these patients were accessed for demographic data, snakebite-related data, treatment provided, clinical presentation and allergic reaction status as a result of antivenom treatment. Results: 141 cases were investigated including 73.8% male and 26.2% female patients. The mean age of the patients was 38.1±17.1years. Age group 30-39 years accounted for highest number of snakebite cases (24.1%). A majority of victims (89.4%) were from the rural areas. Most of the patients (51.8%) were bitten in the spring and highest number of snakebite were reported in May (39.1%). The most common site of snakebite was lower extremities (50.4%) and upper extremities (44.7%). Among clinical feature of snakebite, pain was the most prevalent in 135 cases (95.7%) followed by swelling (83.7%). The mean antivenom vials used were 6.5±3.7 vials. Allergic reactions occurred in 6 patients (4.26%); reactions were mild in 5 patients and sever in 1patient. The commonest presentation was maculopapular rash (1.4%) and the least common were headache (0.71%), nausea (0.71%), fever (0.71) and hypotension (0.71%). Conclusion: Snakebite is one of the significantlife-threatening environmental events.Immediate antivenom treatment can reduce mortality however, patients should be carefully monitored for adverse allergic reactions.


2020 ◽  
Author(s):  
Jae Hyoung Im ◽  
Moon-Hyun Chung ◽  
Hye-Jin Lee ◽  
Hea Yoon Kwon ◽  
JiHyeon Baek ◽  
...  

Abstract Background The spleen contains immune cells and exhibits a pattern of infarction different from other organs; as such, splenic infarction (SI) may provide important clues to infection. However, the nature of the relationship between SI and infectious disease(s) is not well understood. Accordingly, this retrospective study investigated the relationship between SI and infection. Methods Hospital records of patients with SI, who visited Inha University Hospital (Incheon, Republic of Korea) between January 2008 and December 2018, were reviewed. Patient data regarding clinical presentation, causative pathogens, risk factors, and radiological findings were collected and analyzed.Results Of 353 patients with SI, 101 with infectious conditions were enrolled in this study, and their data were analyzed to identify associations between SI and infection. Ten patients were diagnosed with infective endocarditis (IE), and 26 exhibited bacteremia without IE. Twenty-seven patients experienced systemic infection due to miscellaneous causes (negative result on conventional automated blood culture), including the following intracellular organisms: parasites (malaria [n =12], babesiosis [n =1]); bacteria (scrub typhus [n =5]); viruses (Epstein–Barr [n =1], cytomegalovirus [n =1]); and unidentified pathogen[s] (n =7). Splenomegaly was more common among patients with miscellaneous systemic infection; infarction involving other organs was rare. Thirty-eight patients had localized infections (e.g., respiratory, intra-abdominal, or skin and soft tissue infection), and most (35 of 38) had other risk factors for SI. Conclusions In this study, various infectious conditions were found to be associated with SI, and intracellular organisms were the most common causative pathogens. Further studies are needed to examine other possible etiologies and the underlying pathophysiological mechanisms.


2013 ◽  
Vol 5 (1) ◽  
pp. 19-21 ◽  
Author(s):  
Sulabha Joshi ◽  
Sunita Ghike ◽  
Anuja Bhalerao ◽  
Anjali Kawthalkar ◽  
Sayali Kulkarni

ABSTRACT Eclampsia is the leading cause of maternal and perinatal mortality as well as morbidity. This prospective study was carried out at a tertiary institute from Jan 2008 to Dec 2010. Aim and objectives (1) To evaluate the rate of eclampsia in antenatal women attending our hospital, (2) to evaluate the epidemiological factors and clinical presentation in women with eclampsia, (3) to analyze the maternal and perinatal outcome in women with eclampsia, and (4) to formulate strategies to improve the maternal and perinatal outcome. Materials and methods Fifty-five women with eclampsia were evaluated over a period of 3 years. Results During the above period, total number of deliveries were 6,100 out of which 55 were eclampsia giving incidence of —0.9%. The women with eclampsia were treated with magnesium sulfate. Around 70.91% of women had antenatal eclampsia, 18.18% of women had intrapartum eclampsia and 10.91% of women had postpartum eclampsia. Out of 55 women, maternal mortality was 5.45% and perinatal mortality was 25.45%. Conclusion Incidence of eclampsia is higher in developing countries, like India. Magnesium sulfate is an effective anticonvulsant drug leading to cessation of convulsions in 100% cases. Magnesium sulfate toxicity was not observed in any case, indicating effectivity of clinical monitoring during magnesium sulfate therapy. How to cite this article Bhalerao A, Kulkarni S, Ghike S, Kawthalkar A, Joshi S, Somalwar S. Eclampsia: Maternal and Fetal Outcome. J South Asian Feder Obst Gynae 2013;5(1): 19-21.


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