scholarly journals Assessment of Antibiotic use in Pregnant Women in a Tertiary care Teaching Hospital – A Cross Sectional Observational Study

2021 ◽  
Vol 9 (8) ◽  
Keyword(s):  
Urinary Tract ◽  
Observational Study ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Tract Infections

During pregnancy, most women are at risk for respiratory tract infections (RTIs), urinary tract infections (UTIs), and ear, nose, and throat infections. Antimicrobials are the most commonly given medications to treat acquired illnesses during this time. This study aimed to assess antibiotic use in pregnant women in a tertiary care teaching hospital. The present study was a cross- sectional prospective observational study and was conducted for three months in a tertiary care health centre in North Karnataka with 57 participants.All case records of pregnant women who use antibiotics admitted to Obstetrics and Gynecology department and pregnant women with more than 18 years of age were included in the study. Out of 57 participants, 40.3% of them were belonging to the age category of 19-23 years of age, followed by 33.3% in 24-28 years. Most prevalent infections which required antimicrobials prescription were UTIs (36.82%), followed by Gastroenteritis (17.54%) and Pyrexia (14.03%). Majority of the antimicrobials prescribed were from Betalactams (40.34%), followed by Nitrofuranes (29.82%). To assist in making prescribing decisions for pregnant women, health care professionals should examine the teratogenic and toxic risk profiles of antibiotics. These could be especially significant if anti- infective countermeasures are needed to safeguard the health, safety, and survival of people who have been exposed to pathogenic bacteriologic agents as a result of bioterrorism. Keywords: Antimicrobials, pregnancy, teratogenic effect, urinary tract infections

Prevalence of Urinary Tract Infections (UTI) Among Pregnant Women in University Of Benin Teaching Hospital (UBTH) Benin City, Nigeria

2015 ◽  
Vol 5 (4) ◽  
pp. 198-204
Author(s):  
Raphael M Mordi ◽  
Moghene E Burke ◽  
Emmanuel E Odjadjare ◽  
Stephen A Enabulele ◽  
Onyinye Jecinta Umeh
Keyword(s):  
Urinary Tract ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Teaching Hospital ◽  
Benin City ◽  
Tract Infections

scholarly journals A PRESCRIPTION PATTERN STUDY OF RESPIRATORY TRACT INFECTIONS IN PAEDIATRIC INDOOR PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL - A PROSPECTIVE OBSERVATIONAL STUDY

2018 ◽  
Vol 11 (7) ◽  
pp. 251 ◽  
Author(s):  
Vandana Badar ◽  
Vidisha Parulekar ◽  
Priti Garate
Keyword(s):  
Observational Study ◽  
Respiratory Tract ◽  
Teaching Hospital ◽  
Respiratory Tract Infections ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Acute Bronchiolitis ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Tract Infections

Objectives: The objectives of the study were as follows: (1) To study the prescription patterns in Respiratory tract infections (RTI) in indoor patients in pediatric wards. (2) To check the rationality of treatment according to Modified Kunin’s rationality criteria. (3)To analyze the data of RTI by Anatomical Therapeutic Chemical classification.Methods: It was a non-interventional, prospective, observational study which was conducted in indoor pediatric patients in a tertiary care teaching hospital in India. Data were analyzed and evaluated according to the WHO rational use of drugs guidelines.Study sample: The study sample was 174.Study duration: The study duration was August 15, 2016–September 15, 2016.Results: Males (63.79%) were more as compared to females (36.20%), and the highest number of cases was seen in infants (62.06%). Acute bronchiolitis (54.02%) was highest in the incidence followed by Wheeze Associated Lower Respiratory Tract Infection (WALRI) (30.45%). The average duration of patient stay in hospital was 4.71 days whereas 93.33% were polytherapy and mostly prescribed antibiotic was amoxicillin-clavulanic acid in acute bronchiolitis and WALRI. Salbutamol (40.84%) and Ipratropium Bromide (39.43%) were the commonly prescribed respiratory medicines. Oral route (42.27%) was the most common route of administration. 56.11% drugs were prescribed by generic name.Conclusion: Standard treatment guidelines for the treatment of RTI need to be urgently developed and strictly implemented.

scholarly journals Differences of heparin binding protein levels in preeclampsian and non preeclampsian women

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Nurrahma Layuk ◽  
Sitti Wahyuni ◽  
Sharvianty Arifuddin
Keyword(s):  
Urinary Tract ◽  
Pregnant Women ◽  
Urinary Tract Infections ◽  
Binding Protein ◽  
Sampling Technique ◽  
Heparin Binding ◽  
Cross Sectional ◽  
Protein Levels ◽  
Heparin Binding Protein ◽  
Tract Infections

This study aims to the incidence of preeclampsia and determine differences in heparin-binding protein levels in preeclamptic and non-preeclamptic mothers and determine the relationship between urinary tract infections in pregnancy. The research design was cross-sectional on 65 respondents with an accidental sampling technique. The research data were obtained from a questionnaire containing a list of questions given to respondents, measurement of middle urine samples to measure nitrite, leukocytes urine using dipstick method, and to determine heparin binding protein (HBP) levels using the ELISA method in the Hasanuddin University RSP Research Laboratory. The results of the study found there was a difference in the levels of heparin-binding protein in pregnant women without preeclampsia, namely 1.90±0.22 Ng/ml and HBP levels in pregnant women preeclampsia ie 2.39±0.3 Ng/ml. That there was no significant relationship between urinary tract infections (UTI) and the incidence of preeclampsia with p= 0.074. The conclusion in this study is that the levels of heparin-binding protein differ in preeclamptic and non-preeclamptic mothers, the increase in HBP levels in preeclampsia is due to inflammation, the cause is not through UTI. There is no association between urinary tract infections in pregnant women and the incidence of preeclampsia.

scholarly journals Bacteriological Profile and Antibiotic Sensitivity Pattern in Patients with Urinary Tract Infection in Janakpurdham, Nepal

2021 ◽  
Vol 8 (10) ◽  
pp. 5692-5697
Author(s):  
Dr. Digbijay Kumar Thakur ◽  
Dr. Rameshwar Mahaseth ◽  
Dr. Shambhu Kumar Sah
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Urine Culture ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Cross Sectional ◽  
Bacteriological Culture ◽  
Sensitivity Pattern ◽  
Culture And Sensitivity ◽  
Tract Infections

Background: Urinary tract infections are most common bacterial infection in routine clinical practice. It is also most common nosocomial infection in many hospitals. Antibiotics are usually given empirically before urine culture reports available and treatment failure rate used to be significantly high. Study of causative agents and their antimicrobial sensitivity pattern are important factors helping formulating antibiotic policy. Generally, most common uropathogene is Escherichia Coli. Tertiary care hospitals, catering of already partially treated or mal treated patients as major chunk, may have varying etiologies and different sensitivity patterns. Objective: To study the culture and sensitivity patterns of urinary tract infections in patients presenting with urinary symptoms in local hospitals. Study design: A cross sectional study Materials and methods: Study was conducted at Madanta Research Clinic Private Limited from 12th march 021 to 12th September 021. Urine from cases suspected to have symptoms suggestive of UTI were send for bacteriological culture and sensitivity. Demographic profiles of each participant along with pathogen isolated, culture sensitivity pattern was documented. Data analysis was done in IBM spss 25. Results: A total 200 samples were selected for bacteriological culture and sensitivity out of which 32% were male and 68% were female. Around 50% of participants were in age group 20-40. There was no growth in 64% sample. Among positive samples (36%), E. coli (most common) was detected in 91.66%, Klebsiella was detected in 6.94%. Gentamicin, Amikacin and Nitrofurantoin were most common antibiotics sensitive to organisms in culture and Cephalosporins group of antibiotics are commonly resistant. Conclusions: coli is the most common organism isolated in urine culture in our region Janakpur. Cephalosporins are resistant in majority of cases where as Aminoglycosides like Amikacin, Gentamicin and Nitrofurantoin are found to be highly sensitive in most of positive cases.

scholarly journals Antibiotic resistance in isolates recovered from women with community-acquired urinary tract infections presenting to a tertiary care emergency department

CJEM ◽  
2012 ◽  
Vol 14 (05) ◽  
pp. 295-305 ◽  
Author(s):  
Lyne Filiatrault ◽  
Rachel M. McKay ◽  
David M. Patrick ◽  
Diane L. Roscoe ◽  
Grahame Quan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Emergency Department ◽  
Antibiotic Resistance ◽  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Adult Females ◽  
Tract Infections

ABSTRACTIntroduction:We sought to determine the antibiotic susceptibility of organisms causing community-acquired urinary tract infections (UTIs) in adult females attending an urban emergency department (ED) and to identify risk factors for antibiotic resistance.Methods:We reviewed the ED charts of all nonpregnant, nonlactating adult females with positive urine cultures for 2008 and recorded demographics, diagnosis, complicating factors, organism susceptibility, and risk factors for antibiotic resistance. Odds ratios (ORs) and 95% confidence intervals (CIs) for potential risk factors were calculated.Results:Our final sample comprised 327 UTIs: 218 were cystitis, of which 22 were complicated cases and 109 were pyelonephritis, including 22 complicated cases.Escherichia coliaccounted for 82.3% of all UTIs, whereasStaphylococcus saprophyticusaccounted for 5.2%. In uncomplicated cystitis, 9.5% of all isolates were resistant to ciprofloxacin and 24.0% to trimethoprim-sulfamethoxazole (TMP-SMX). In uncomplicated pyelonephritis, 19.5% of isolates were resistant to ciprofloxacin and 36.8% to TMP-SMX. In UTI (all types combined), any antibiotic use within the previous 3 months was a significant risk factor for resistance to both ciprofloxacin (OR 3.34, 95% CI 1.16–9.62) and TMP-SMX (OR 4.02, 95% CI 1.48–10.92). Being 65 years of age or older and having had a history of UTI in the previous year were risk factors only for ciprofloxacin resistance.Conclusions:E. coliwas the predominant urinary pathogen in this series. Resistance to ciprofloxacin and TMP-SMX was high, highlighting the importance of relevant, local antibiograms. Any recent antibiotic use was a risk factor for both ciprofloxacin and TMP-SMX resistance in UTI. Our findings should be confirmed with a larger prospective study.

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