scholarly journals Prevalence of polycystic ovarian syndrome among selected group of Sudanese housewives with infertility disorders

2019 ◽  
Vol 2 (01) ◽  
Author(s):  
Mohammed A.Gafoor A.Gadir ◽  
Mohammed Omer Mohammed Hussein ◽  
Mosab Nouraldein Mohammed Hamad
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Clinical Symptoms ◽  
Polycystic Ovary ◽  
Pancreatic Beta Cell ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Cell Dysfunction ◽  
Increased Risk ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS), also recognized as the Stein-Leventhal syndrome, is one of the most widespread endocrinopathies between women of reproductive age. Hyperinsulinemia in mixture with pancreatic beta cell dysfunction consequences in an increased risk of numerous illnesses, counting type 2 diabetes, hypertension, dyslipidemia, endothelial dysfunction, atherosclerosis and cardiovascular diseases. Insulin also stimulates the theca cells of the ovary to create excessive testosterone, which is accountable for the clinical symptoms of hyperandrogenism

scholarly journals The effect of progressive muscle relaxation on depression in polycystic ovarian syndrome

2018 ◽  
Vol 7 (8) ◽  
pp. 3029
Author(s):  
Jyoti Parle ◽  
Aishwarya D. Savant
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Exclusion Criteria ◽  
Before And After ◽  
Muscle Groups ◽  
Ovarian Syndrome

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age. Authors explored the effects of progressive muscle relaxation (PMR) on depression in females with polycystic ovarian syndrome (PCOS).Methods: In a 4-week study duration in which the intervention was for three times a week, 30 females which were selected according to the inclusion and exclusion criteria received a PMR protocol in which subjects were taught to contract and relax 16 muscle groups. The Becks Depression Inventory (BDI) was taken before and after the intervention as a depression analysis tool.Results: After 4 weeks of intervention, the patients showed significant improvement in depression (P < 0.05).Conclusions: In conclusion, this study suggests that PMR practice is effective in improving depression, in patients with PCOS.

COMPLICATIONS OF PREGNANCY IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

2011 ◽  
Vol 22 (3) ◽  
pp. 188-206
Author(s):  
MALLIKA AZIZIA ◽  
PAUL HARDIMAN
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Polycystic Ovaries ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS) is a common hormonal disorder affecting around 5–8% of women of reproductive age. It has a variable clinical spectrum including hyperandrogenism, menstrual abnormalities, polycystic ovaries and metabolic features like diabetes mellitus, obesity and dyslipidaemia. The manifestation of PCOS and its impact especially on reproductive function and pregnancy are profoundly affected by associated features of obesity/raised body mass index and metabolic syndrome.

scholarly journals A Detailed Research on Detection of Polycystic Ovary Syndrome from Ultrasound Images of Ovaries

2019 ◽  
Vol 8 (2S11) ◽  
pp. 467-472
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Ultrasound Images ◽  
Time Analysis ◽  
Ovary Syndrome ◽  
Endocrine Disorder ◽  
Real Time Analysis ◽  
Ovarian Syndrome ◽  
Biochemical Abnormalities

A common endocrine disorder named polycystic ovarian syndrome (PCOS) usually occurs to several women’s during their reproductive age. This type of disease leads to infertility which represent with amenorrhea and hirsutism. The combination of clinical, endocrinological, and biochemical abnormalities are known to be PCOS which particularly related with the metabolism of estrogen and androgens. The periphery of ovaries is identified with the most common immature follicles which are less than 10mm. Analyzing this kind of situations in women is a major challenge which now doctors used ultrasound images which have the necessary details like number of follicles, size, and position. For real-time analysis of PCOS is a major task as follicles contains different sizes and highly connected with tissues and blood vessels which results in error prone. Several researchers have proposed different techniques for analyzing the PCOS using the ultrasound images of ovaries. In this study, we analyze the important factors and techniques used in detection of PCOS by using the ultrasound images taken from the women’s ovary and compared the results of existing works.

scholarly journals An Overview of Harmful Effects of Polycystic Ovary Syndrome

2021 ◽  
pp. 1-5
Author(s):  
Anisa Iftikhar ◽  
Keyword(s):  
Patient Management ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Metabolic Effects ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Harmful Effects ◽  
Hormone Imbalance ◽  
Ovarian Syndrome

PCOS, a hormone imbalance that causes infertility, obesity etc. Polycystic ovarian syndrome (PCOS) is the most frequent endocrinopathy among women of reproductive age. It is the most common female endocrine disorder with prevalence rates ranging from 4% to 18%. There are many associated condition with PCOS like obesity, many types of cancer, infertility, cardiac diseases etc. It is confirm that women who have this syndrome are at risk more than other women. The treatment of PCOS is determined by whether a woman wishes to become pregnant or not. If pregnancy is not a goal, then weight loss, oral contraceptives, and the diabetes medication. It should also include all metabolic effects and potential problems. More study and knowledge of the biology of PCOS will lead to better treatment outcomes and patient management.

scholarly journals Ovarian aromatase activity in polycystic ovarian syndrome

2014 ◽  
Vol 63 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Igor Pavlovich Nikolayenkov ◽  
Vladimir Vsevolodovich Potin ◽  
Marina Anatolyevna Tarasova ◽  
Natalya Nikolayevna Tkachenko ◽  
Maria Igorevna Yarmolinskaya ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Free Testosterone ◽  
Antral Follicle ◽  
Reproductive Age ◽  
Blood Levels ◽  
Aromatase Activity ◽  
Ovary Syndrome ◽  
Antral Follicles ◽  
Ovarian Syndrome

41 women with polycystic ovary syndrome (PCOS) and 15 healthy women of reproductive age were examined to evaluate ovarian aromatase activity. Aromatase activity was determined by the decrease of estradiol level after peroral intake of aromatase inhibitor letrosol. To examine aromatase activity of antral follicle (∆E2) was divided on the blood level of antimullerian hormone (AMH), which is corresponded to the number of antral follicles. Significant variations of aromatase activity of antral follicles in patients with PCOS were determined: in 34.1 % of women it was within physiological ranges, in 48.8 % of women it was decreased and in 17.1 % of women it was increased. Aromatase activity of antral follicles in patients with PCOS correlated with blood levels of estradiol (r = 0.67), estron (r = 0.27), free testosterone(r = 0.43), androstendion (r = 0.34) and body mass index (r = 0.30). Aromatase activity had reverse correlation with number of antral follicles. Athors suggest that the sensitivity of the ovaries to gonadotropinic stimulation is decreased in patients with PCOS and low aromatase activity.

scholarly journals Is serum amylase normal in women with polycystic ovarian syndrome?

2014 ◽  
Vol 11 (4) ◽  
pp. 1583-1591
Author(s):  
Baghdad Science Journal
Keyword(s):  
Insulin Resistance ◽  
Metabolic Disorders ◽  
Polycystic Ovarian Syndrome ◽  
Serum Amylase ◽  
Amylase Activity ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Reproductive Age Women ◽  
Ovarian Syndrome

Background : Polycystic ovary syndrome (PCOS) is the most common cause of infertility in reproductive-age women , it is an important harbinger of metabolic disorders. It has been reported that hyperamylasemia can be used as marker of ovarian cancer patients . The current study was conducted to evaluate amylase activity and to estimate the correlation of this enzyme with insulin and insulin resistance in PCOS patients. Methods: This study was conducted on forty five patients with PCOS in comparison to twenty five women as control. Fasting blood sample was taken from each subject and analyzed for amylase activity , FSH,LH, Insulin , proteins, and blood sugar , meanwhile insulin resistance was determined by HOMA-IR index. Results: The results of the study showed a significant increase (p

scholarly journals Adiponectin and Polycystic Ovary Syndrome

2010 ◽  
Vol 12 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Susan W. Groth
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Clinical Practice ◽  
Polycystic Ovary Syndrome ◽  
Disease Risk ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Increased Risk

Introduction. Polycystic ovary syndrome (PCOS) has a prevalence of 5—8% in women of reproductive age. Women with PCOS have an increased risk of metabolic syndrome and associated comorbidities. Adiponectin is a circulating protein produced by adipocytes. Circulating levels of adiponectin are inversely related to adipocyte mass. Low levels occur with insulin resistance, type 2 diabetes, metabolic syndrome, and obesity-related cardiovascular disease. This article reviews the literature on the link between adiponectin and PCOS and the potential use of adiponectin as a biomarker for PCOS. Method. Data-based studies on adiponectin and PCOS and adiponectin measurement were identified through the Medline (1950—2009) and ISI Web of Knowledge (1973—2009) databases. Results. Fifteen studies related to adiponectin and PCOS met inclusion criteria and were included in this review. These studies present evidence that adiponectin is linked to insulin resistance, insulin sensitivity, body mass index (BMI), and adiposity. In women with PCOS, lower levels, as opposed to higher levels, of adiponectin occur in the absence of adiposity. Conclusion. The relationships between adiponectin and insulin resistance and sensitivity, metabolic syndrome, and BMI in women with PCOS suggest that adiponectin potentially could serve as a marker for disease risk and provide opportunity for earlier intervention if knowledge is successfully translated from laboratory to clinical practice. However, further study of the relationship between adiponectin and PCOS is required before there can be direct application to clinical practice.

scholarly journals Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome

2017 ◽  
Vol 3 (4) ◽  
pp. 116-118
Author(s):  
CH Chandra Smitha ◽  
Mo Orkoth Prasannan Anantha Sailakshmi ◽  
Rangaiah Nagaratnamma
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Increased Risk ◽  
Management Of Complications ◽  
The Common ◽  
Ovarian Syndrome

ABSTRACT In women of reproductive age polycystic ovary syndrome (PCOS) is the common endocrine disorder. It is one of the common causes of infertility due to anovulation. There is no single criterion for the diagnosis of this syndrome. It is crucial to diagnose PCOS early in its course since it has lifelong implications with increased risk for metabolic syndrome, type II Diabetes mellitus (DM), cardiovascular disease, endometrial hyperplasia, infertility and depression. Screening for the impaired glucose (IGT), allows for proper and timely prevention and management of complications. In this cross sectional study, we planned to detect the prevalence of impaired glucose tolerance and diabetes in women with PCOS which will facilitate prevention of long term sequelae. We also studied the extent of the risk for diabetes in patients with PCOS in relation to age, socioeconomic status, rural and urban areas, BMI, waist/hip circumference ratio, family history of PCOS and diabetes mellitus How to cite this article Smitha CHC, Sailakshmi MOPA, Nagaratnamma R. Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome. J Med Sci 2017;3(4):116-118.

scholarly journals Valproate, bipolar disorder and polycystic ovarian syndrome

2016 ◽  
Vol 69 (3-4) ◽  
pp. 121-126 ◽  
Author(s):  
Milana Okanovic ◽  
Olga Zivanovic
Keyword(s):  
Bipolar Disorder ◽  
Polycystic Ovarian Syndrome ◽  
Treatment Guidelines ◽  
Polycystic Ovary ◽  
The United States ◽  
Reproductive Age ◽  
Hormonal Changes ◽  
Polycystic Ovaries ◽  
Increased Risk ◽  
Ovarian Syndrome

Introduction. Polycystic ovarian syndrome is a syndrome of ovarian dysfunction with the principal features of hyperandrogenism and polycystic ovary morphology. A large number of studies conducted on this topic have suggested a possible role of anticonvulsants, particularly valproate, in the pathogenesis or risk factors associated with polycystic ovarian syndrome. Bipolar treatment guidelines from Canada and the United States of America recommend valproate as the first line strategy in the acute treatment of bipolar disorder. Discussion. Most persons with bipolar disorder require maintenance treatment. Long-term administration of valproate in women with bipolar disorder or epilepsy is believed to result in the increased risk of hyperandro?genism, menstrual abnormalities and polycystic ovaries. Valproate may also increase the risk of infertility and other associated symptoms of polycystic ovarian syndrome. Therefore, particular caution is indicated in the use of valproate in women of reproductive age. Conclusion. The treatment of the female patients with bipolar disorder presents various challenges for the clinician. Every woman of reproductive age needs to know the risk and benefits of her pharmacologic treatment options. Bipolar disorder should be considered chronic disorder, whose development is largely affected by hormonal changes and reproductive cycle in women. These issues should be researched more thoroughly in order to opt for the most appropriate treatment in women with bipolar disorder.

scholarly journals Complex diseases and co-morbidities: polycystic ovary syndrome and type 2 diabetes mellitus

2019 ◽  
Vol 8 (3) ◽  
pp. R71-R75 ◽  
Author(s):  
Raymond J Rodgers ◽  
Jodie C Avery ◽  
Vivienne M Moore ◽  
Michael J Davies ◽  
Ricardo Azziz ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Population Attributable Risk ◽  
Complex Diseases ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Increased Risk

Objective Many complex diseases exhibit co-morbidities often requiring management by more than one health specialist. We examined cross-speciality issues that ultimately affect the health and wellbeing of patients with polycystic ovary syndrome (PCOS). PCOS was originally described as a reproductive condition but is now recognised to also be a metabolic and psychological condition affecting 8–13% of women of reproductive age. With a four-fold increased risk of type 2 diabetes (DM2), the Population Attributable Risk of DM2 that could be avoided if PCOS were eliminated is a substantial 19–28% of women of reproductive age. To determine the extent to which PCOS is an important consideration in diabetes development, we examined publications, funding, guidelines and predictors of risk of developing DM2. Results We found that the topic of PCOS appeared in specialist diabetes journals at only 10% the rate seen in endocrinology journals – about 1 in 500 articles. We found research funding to be substantially less than for diabetes and found that diabetes guidelines and predictive tools for DM2 risk mostly ignore PCOS. This is surprising since insulin resistance in women with PCOS has a different aetiology and additionally women with PCOS are at increased risk of becoming overweight or obese – high risk factors for DM2. Conclusions We consider the causes of these concerning anomalies and discuss current activities to address the co-morbidities of PCOS, including the recent development of international guidelines, an international PCOS awareness program and potentially changing the name of PCOS to better reflect its metabolic consequences.

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