scholarly journals EVALUATION OF EFFICACY OF JALOUKAVACHARANA AND SIRAVYADHANA IN THE MANAGEMENT OF VATARAKTA: A COMPARATIVE STUDY

2020 ◽  
pp. 47-55
Author(s):  
Rajeshwari ◽  
Deenaprakash Bharadwaj ◽  
Harshavardhana K
Keyword(s):  
Dietary Habits ◽  
Alternative Hypothesis ◽  
Total Duration ◽  
Standard Technique ◽  
Signs And Symptoms ◽  
Cost Effective ◽  
Inclusion Criteria ◽  
Group A ◽  
Group B

Vatarakta is the illness that exhibits different signs and symptoms based upon the Dosha, Utthana and Gambheera Avastha. Dietary habits and life style modalities play a major role in the causation of Vatarakta. Though various remedies are there to treat it, Raktamokshana is said to be an effective, and standard technique. Hence it is claimed to be an important affective tool in the management of Vatarakta. This study is undertaken to explore and compare the efficacy of Jaloukavacharana and Siravyadhana in Vatarakta. Randomized comparative clinical trial was adopted in this study. 40 subjects fulfilling diagnostic and inclusion criteria were selected and divided into two groups. The day on which the procedure was conducted was considered as first day of the trail. Follow up was on 8th & 15th day. Total duration of Study was 15 days. In both the group there is a significant improvement of subjective and objective symptoms except on Vaivarnya. The collected data is statistically analysed Jaloukavacharana is found to be more effective in the features Daha and Shopha. Siravydhana is more effective in Shoola and Vivarnya. Both the procedure shows equal effect on Sparshaasahatva. The overall results of Group A are 82.11% and Group B is 82.76%. Both the treatments are equally effective in Vatarakta. Hence alternative hypothesis H3 is proved. This simple and cost-effective treatments are painless do not require any anaesthesia. Hence it can be easily performed in OPD level on day-care basis.

Prospective clinical trial in the management of Mutrashmari through Avapidaka Snehapana and Matra Basti

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr.Savita Metri ◽  
Dr.Prashanth A. S.
Keyword(s):  
Clinical Trial ◽  
Total Duration ◽  
Treatment Modalities ◽  
Single Subject ◽  
Study Group ◽  
Inclusion Criteria ◽  
Before And After ◽  
Group A ◽  
Group B

Background: Ashmari Roga is considered as one of the Ashta Maha Gada considered difficult to cure because of its Marma Ashrayatwa, due to the involvement of Bahu Dosha and Basti, which is one of the Tri Marma, Acharyas has specifically mentioned many treatment modalities for reducing the symptoms as well as eliminating the Ashmari from its root, in which Basti and Virechana is having prime importance. So here an attempt is made to compare and study the efficacy of Basti and Virechana in Mutrashmari. Objective: To study the effect of Avapidaka Snehapana followed by Virechana and Shamanoushadhi and Matrabasti followed by Shamanoushadhi in the management of Mutrashmari. Materials and methods: 40 patients diagnosed with Mutrashmari (urinary calculus) and fulfilling the inclusion criteria were selected and randomly divided into 2 groups. In Group A: Amapachana with Hingvastaka Churna, Avapidaka Sneha with Punarnavadi Ghrita and Virechana with Trivrut Mrudvika Rasa followed by Shuntyadi Kwatha as Shamanoushadhi, In Group B: Amapachana with Hingvastaka Churna, Varunadhya Taila Matra Basti followed by Shwadamstra Kwath as Shamanoushadhi. Pain (from loin to groin), Nausea, Dysuria, Haematuria, Burning Micturation, Number of stones, Size of stones, Site of stone, Hydroureter and Hydronephrosis were assessed before and after treatment. The total duration of the study was 60 days or up to expulsion of the stone with 45 days of follow up. Results: In this study, Group A shows statistically more significant result than Group B. Conclusion: Both Group A and Group B have shown significant outcomes in all parameters with proper diet and regimen. Reoccurrence of stone was not found in a single subject.

scholarly journals A COMPARATIVE STUDY TO EVALUATE THE EFFECT OF MATRA VASTI IN KHARA PAKA WITH MADHYAMA PAKA IN JANU SANDHIGATA VATA

2021 ◽  
Vol 9 (4) ◽  
pp. 713-718
Author(s):  
Thulasi T.V ◽  
Joshi George ◽  
Rahul H
Keyword(s):  
Joint Stiffness ◽  
General Rule ◽  
Signs And Symptoms ◽  
The Body ◽  
Inclusion Criteria ◽  
Group A ◽  
Total Body ◽  
Group B ◽  
Therapeutic Administration

Vasti has been told as Ardhachikitsa and is applicable in all the Vatavyadhi. As a general rule, when Rogas are caused by Vata Dosha alone, without the association of Ama, then Sneha Vasti should be given. Matra Vasti is one among the Bheda of Sneha Vasti, it can be given to any person irrespective of age and Ritu, without any strict regimen of Ahara and Vihara. SandhiVata is a Vatika disorders and Dhatukshaya is its prime factor. Vata Dosha is the regulator of other two Dosha, Dhatu and Mala and also all the body activities. Therefore, once Vata is con- trolled by Vasti, all these factors are automatically regulated, and total body equilibrium is achieved. Sandhigata Vata is characterized by symptoms like joint stiffness, joint pain, swelling and difficulty in joint movements, etc. Snehana is mentioned as one of the main treatments of Sandhigata Vata. According to therapeutic administration, Sneha Paka is mainly 3. Acharya Charaka and Vagbhata explained Sneha in Madhyama Paka for Vasti Karma, whereas Acharya Susruta opines Sneha in Khara Paka for VastiKarma. Here in this study, MatraVasti with KsheeraBala Taila prepared in two different Paka is selected. A group of 40 patients with signs and symptoms of Janu Sandhigata Vata, fulfilling the inclusion criteria and were randomly divided into two groups with number of twenty. MatraVasti with Ksheerabala Taila prepared in Khara Paka was given to Group A and Madhyama Paka was given to Group B for consecutive 9 days. Patients were evaluated thoroughly prior to the treatment, on 9th day of treatment and on 18th day of follow up period on the basis of subjective and objective parameters. Statistical analysis revealed that both groups were statistically significant in all subjective and objective criteria in after treatment results and after following up results.

A Study on Frozen Shoulder and its clinical management through Nasaapana and Nasya

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Praveenkumar H. Bagali ◽  
A. S. Prashanth
Keyword(s):  
Medical Science ◽  
Frozen Shoulder ◽  
Signs And Symptoms ◽  
Treatment Modalities ◽  
Animal Kingdom ◽  
Shoulder Joints ◽  
Group A ◽  
Group B

The unique position of man as a master mechanic of the animal kingdom is because of skilled movements of his hands and when this shoulder joints get obstructed, we call it as Apabahuka (Frozen shoulder), we do not find satisfactory management in modern medical science. Various effective treatment modalities have been mentioned which reverse the pathogenesis, Shodhana is advised initially followed by Shamana therapies. In the present study 30 patients were selected incidentally and placed randomly into two groups A and B, with 15 subjects in each group. Group A received Amapachana with Panchakola Churna, Jambeera Pinda Sweda and Nasya Karma. Group B received Amapachana with Panchakola Churna, Jambeera pinda Sweda and Nasaapana. In both the groups two months follow up was done. Both groups showed significant improvement in the signs and symptoms of Apabahuka as well as the activities of daily livings, thereby improving the quality of life of the patients. Nasya Karma and Nasaapana provided highly significant results in all the symptoms of Apabahuka. In the present study as per the clinical data, Nasaapana is found to be more effective than Nasya Karma.

scholarly journals Role of Panchamooladya Choorna in Grahani Roga (irritable bowel syndrome)-pilot study

2020 ◽  
Vol 4 (06) ◽  
Author(s):  
Akshaya Patil
Keyword(s):  
Irritable Bowel Syndrome ◽  
Dietary Habits ◽  
Modern Medicine ◽  
Disturbed Sleep ◽  
Principal Factors ◽  
Group A ◽  
Irritable Bowel ◽  
Group B

Lifestyle disorders like unhealthy dietary habits, physical habits, disturbed sleep and rest patterns are the principal factors that cause many digestion related disease. Irritable bowel syndrome (IBS) is also one such disease which occurs due to the ingestion of unwholesome diet causing disturbances in Agni. According to Ayurvedic science, this disease can be considered as a Grahani roga. So we may consider IBS as Grahani roga. Various herbal medications and panchakarma (biopurification) procedures are described in the treatment of Grahani roga though there is no reliable medical treatment for IBS in modern medicine; various efforts have been made to overcome this problem by the virtue of Ayurvedic therapy. The present study was done to assess the efficacy of Panchmooladya choorna with Takra(buttermilk) as anupan in Group A(10Patients) and Group B(10Patients)with luke warm water as anupan in management of Grahani roga in total of 20patients.The results of therapy were assessed by various parameters after 1month with follow up of 15days.The result concluded that Panchmooladya choorna with Takra as anupan reduced the symptoms of Grahani rog as compared to Group B.

scholarly journals MANAGEMENT OF ASRIGDARA WITH KUTAJASHTAKA AVALEHA AND YASHTIMADHU GHRITA MATRA BASTI - AN OPEN LABEL, DOUBLE ARM, RANDOMIZED CLINICAL TRIAL

2020 ◽  
Vol 8 (10) ◽  
pp. 4701-4709
Author(s):  
Stuti Sharma ◽  
Meenakshi Pandey
Keyword(s):  
Medical Therapy ◽  
Signs And Symptoms ◽  
Reproductive Age ◽  
New Delhi ◽  
Open Label ◽  
Surgical Interventions ◽  
Rectal Route ◽  
Group A ◽  
Group B

Introduction: The word Asrigdara explains about prolonged, cyclic or acyclic excessive menstrual bleed-ing in Ayurveda. 9-14% of women in their reproductive age lose 80 ml of blood in each cycle. It is the most common cause of Anemia. Traditionally, Heavy Uterine Bleeding is managed with medical therapy and surgical intervention with associated side effects. But due to limitation of medical therapy as well as surgical interventions, it becomes the necessity of time to find out a permanent, easy, effective and less side effect producing care which can be easily administered and accepted by the patient. Objective: To evaluate the clinical efficacy of Kutajashtaka Avaleha orally and combination of Kutajashtaka Avaleha and Yashtimadhu Ghrita matra basti in combating the signs and symptoms of Asrigdara. Materials and Methods: 56 patients were selected from the Stri Roga and Prasuti Tantra OPD, All India Institute of Ayur-veda, New Delhi and randomly divided into 2 groups. Group A was administered with Kutajashtaka Ava-leha orally regularly for the period of 3 months with the doses of 5gm BD after meal with water, while in Group B, Combination of Yashtimadhu Ghrita Matra Basti (60 ml for 7 days in 3 consecutive cycles after meal through rectal route after 7th day of menses) for 3 months and Kutajashtaka Avaleha was given and the follow up period of 1 month without medication was same for both the groups. Results: Kutajashtaka Avaleha orally alone and Combination of Yashtimadhu Ghrita Matra Basti & Kutajashtaka Avaleha oral both gave statistically highly Significant results (P<0.001) but with better results when the treatment was combined and Markedly Improved (51-75% relief) the signs and symptoms. Conclusion: Combination of Yashtimadhu Ghrita Matra Basti & Kutajashtaka Avaleha oral gave more statistically significant results than Kutajashtaka Avaleha orally alone. No adverse effects were reported during the entire trial period.

A Comparative Clinical Study on Phalatrikadi Kwata and Darvyadi Kwatha in the management of Kamala w.s.r. to Jaundice

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Kallanagouda H. ◽  
S. C. Sarvi
Keyword(s):  
Clinical Study ◽  
Dietary Habits ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Mucous Membranes ◽  
Comparative Clinical Study ◽  
Group A ◽  
Clinical Signs And Symptoms ◽  
Ayurvedic Treatment ◽  
Group B

Background: Jaundice (Kamala) is a yellowish pigmentation of the skin, the conjunctival membranes over the sclera (whitish of the eyes), and other mucous membranes caused by hyperbilirubinemia (increased levels of bilirubin in the blood). Today’s lifestyle with unhygienic and poor dietary habits and alcoholic habits etc. are responsible factors to promote hepatic damage which clinically reflects as Kamala Roga. The incidence of such causes resulting in Jaundice. In India it is 2.37-3.15 per 1000 population. The effect of Ayurvedic treatment was assessed in relation to improvement in overall clinical signs and symptoms. Objectives: To evaluate the effect of Phalatrikaadi Kwatha and Darvyadi Kwatha in Kamala Roga. Methodology: A comparative clinical study was conducted on Kamala for period of 15 days. The patients were divided into 2 groups. In Group A 20 patients were administered with Phalatrikadi Kwatha internally and in Group B 20 patients were administered with Darvyadi Kwatha internally. Results: Group A and Group B have shown statistically significant result. Group B treated with Darvyadi Kwatha showed better result compared with Group B treated with Phalatrikadi Kwatha.

scholarly journals DACRYOCYSTORHINOSTOMY

2008 ◽  
Vol 15 (01) ◽  
pp. 81-86
Author(s):  
MUHAMMAD NAWAZ ◽  
MUHAMMAD SULTAN ◽  
QAISAR HANIF ◽  
Muhammad Sadiq
Keyword(s):  
Symptomatic Relief ◽  
Cost Effective ◽  
Medical College ◽  
Chronic Dacryocystitis ◽  
Department Of Ophthalmology ◽  
Silicon Tube ◽  
Group A ◽  
Group B ◽  
Study Setting

Purpose: To compare the results of standard dacryocystorhinostomy with the results ofdacryocystorhinostomy done with silicon tube stentting of the lacrimal canaliculi. Study design: This is a hospitalbased, prospective, comparative and interventional study. Setting: Department of Ophthalmology, Allied HospitalPunjab Medical College Faisalabad. Period: January 2006 to December 2006. Methods: Twenty seven patients ofchronic dacryocystitis fulfilling the inclusion criteria were selected and divided in two groups. Group A consisted of 15patients who underwent standard dacryocystorhinostomy and Group B consisted of 12 patients who underwentdacryocystorhinostomy along with intubation of the lacrimal canaliculi with silastic tubes. All the patients were followedup for at least six months post-operatively. Success of the procedure, defined as the symptomatic relief of epiphoraand infection was assessed at the end of follow-up period. Results: Of the total 27 patients of chronic dacryocystitis23 (85%) were female and 4(15%) were male. The mean age of the patients was 45 years. The success of theprocedure was recorded in 14 (93.33%) patients in group-A and in 10 (83.33%) patients in group B. Quite a few andsimple complications were recorded during the study period. Conclusions: 1. Standard externaldacryocystorhinostomy is a simple and cost effective procedure forthe management of chronic dacryocystitis. 2. Silicontube stentting of the lacrimal canaliculi does not have any extra advantage in the management of chronic dacryocystitiswithout canalicular obstruction.

scholarly journals Anti-albuminuric effects of spironolactone and its effect along with ramipril in type-2 diabetic nephropathy

2019 ◽  
Vol 6 (1) ◽  
pp. 140
Author(s):  
Richa Giri ◽  
Ashish Naresh ◽  
J. S. Kushwaha ◽  
Brijesh Kumar ◽  
R. K. Verma ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Ace Inhibitor ◽  
Total Duration ◽  
P Value ◽  
Protective Effects ◽  
Mean Values ◽  
Group A ◽  
Group B

Background: The study was conducted to evaluate and compare the protective effects of spironolactone (alone) and its effects along with ACE inhibitor (ramipril) on diabetics (30-70year) in relation to proteinuria and state of diabetic nephropathy.Methods: A comparative, prospective, non-randomized, non-blinded experimental study was conducted on 56 patients (30-70year) of diagnosed type 2 diabetes mellitus showing proteinuria. Total duration of study was about one year from October 2017 to October 2018. Patients were divided in two groups, group A (n=28, spironolactone 25mg and ramipril 5mg) and group B (n=27, spironolactone 25mg). Subjects were followed over 12weeks and baseline and 12-week urine ACR being compared.Results: Both the group after receiving respective drug were followed for 3month duration and response were assessed by measuring urine ACR value at end of 3months. Mean values of baseline and follow up urine ACR for group A and group B were 471.5±465.62, 244.66±237.54 and 474.88±438.94, 268.42±268.16 respectively, P value found to be >0.05 at 95%C.I. It was observed that percentage reduction of urine ACR were 48% and 43.47% in group A and group B respectively.Conclusions: In the study, it was concluded that spironolactone had significant effect over proteinuria reduction over follow up period in patient with diabetic nephropathy though there was no additional statistically significant advantage of addition of spironolactone and ACE inhibitor over proteinuria reduction. Significant reduction of proteinuria occurred in both group A and group B over 12weeks follow up period, 48 % reduction in group A and 43.47% in group B.  This difference proved statistically not significant after applying independent t-test.

scholarly journals OSTEOARTHRITIS;

2014 ◽  
Vol 21 (03) ◽  
pp. 471-476
Author(s):  
Malik Muhammad Yasin Awan ◽  
Ijaz Ahmad ◽  
Amer Aziz
Keyword(s):  
Case Report Form ◽  
Inclusion Criteria ◽  
Double Blind ◽  
Treatment Groups ◽  
End Of Treatment ◽  
Womac Questionnaire ◽  
Group A ◽  
Vas Scores ◽  
Group B

Objective: To assess the efficacy and safety of aceclofenac in the treatment ofosteoarthritis. Study design: Randomized double blind Phase IV trial. Place and Duration ofstudy: This study was conducted in the department of Orthopaedics & Spine Surgery, GhurkiTrust Teaching Hospital, Lahore. The duration was eight weeks. Methodology: A total of 90subjects, fulfilling the inclusion criteria and willing to give free informed consent were enrolled inthis trial. All these subjects were randomized into two treatment groups (A & B). Subjects eitherreceived Aceclofenac 100 mg twice daily or Diclofenac 75 mg twice daily for 08 weeks. During thescreening visit, information on their demographic characteristics, medical history and previousand current medications were collected. A thorough physical examination and necessarylaboratory investigations were carried out before drug administration and after the completion oftreatment (end of week 8). Clinical examination was done at baseline visit, randomization and 2, 4and 8 weeks. Gastrointestinal (GI) safety was assessed using adverse drug reaction (ADR)reports. WOMAC questionnaire was used to see improvement in activities of daily living and painwas assessed using visual analogue scale (VAS). All data was collected in the case report form(CRF). Statistical evaluation was performed at the end of the trial and results were analyzed usingSPSS. Results: 70 subjects completed the study while 20 were lost in follow-up. There were 28males and 34 females in the study with mean age of 56 years. There was a significant decrease inWOMAC and VAS scores in both groups. In group A (Diclofenac group) VAS decreased from7.107 to 2.538 (p= 0.000) and WOMAC decreased from 32.75 to 7.38 (p=0.000). In group B(Aceclofenac group), VAS decreased from 7.912 to 6.0 (p=0.001) while WOMAC decreased from37.29 to 21.50 (p=0.000) showing the efficacy of both drugs. There was also significant decreasein the disease severity in both groups at the end of treatment. But the safety profile of (Diclofenac)group A was not significant (p=0.767) as compared to (Aceclofenac) group B (p=0.022).Conclusions: Aceclofenac is efficacious and safe drug for the treatment of osteoarthritis in adultsas compared to Diclofenac.

Clinical utility of determining tumor markers in patients with signs and symptoms of cancer

2015 ◽  
Vol 53 (3) ◽  
Author(s):  
Jaume Trapé ◽  
Maria Sala ◽  
Fina Franquesa ◽  
Josep M. Ordeig ◽  
Josep M. Soler-Bel ◽  
...  
Keyword(s):  
Tumor Markers ◽  
Clinical Utility ◽  
Hepatic Dysfunction ◽  
Total Bilirubin ◽  
Signs And Symptoms ◽  
Final Diagnosis ◽  
Wasting Syndrome ◽  
Group A ◽  
Group B

AbstractDiagnosing patients with signs or symptoms suggestive of cancer is difficult. Serum tumor markers (TM) may be useful, but it is known that a range of pathologies other than cancer can increase their concentrations and so TM data must be interpreted with caution. The aim of this study is to determine the diagnostic accuracy of TMs in patients with signs or symptoms of cancer.We prospectively studied 234 patients seen at rapid diagnostic units who presented signs or symptoms suggestive of cancer. Ninety patients had wasting syndrome, 74 had pulmonary symptoms and 70 other presentations. CYFRA21-1, CEA, CA19-9, total bilirubin and creatinine were determined. The final diagnosis was obtained after 6 months’ follow-up. Patients were classified according to the absence (group A) or presence (group B) of abnormal bilirubin or creatinine.Of the 234 patients studied, 103 (44.0%) had tumors diagnosed. Cut-off points for each TM were calculated for a specificity of 100%. For the total group, the values were CYFRA21-1, 15 μg/L, CEA, 43.8 μg/L and CA19-9, 7428 KU/L, with an overall sensitivity of 46.6%. For group A (n=142), the following cut-off points were established: CYFRA21-1, 7.8 μg/L, CEA, 13.8 μg/L and CA19-9, 101 KU/L, obtaining a sensitivity of 68.6%. For group B (n=92), the values were the same as for the whole group, and a sensitivity of 42.4% was achieved.We conclude that TMs can aid diagnosis in these patients with signs or symptoms suggestive of cancer. Their sensitivity can be improved by using different cut-off points in the presence and absence of renal and hepatic dysfunction.

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