scholarly journals MEDICINAL IMPORTANCE OF MOLLUGO VERTICILLATA (MOLLUGINACEAE): A REVIEW

2021 ◽  
pp. 46-50
Author(s):  
Gandepalli Pratap Kumar ◽  
Nusrathulla Shariff
Keyword(s):  
Traditional Medicine ◽  
Plant Extract ◽  
Research Work ◽  
Current Situation ◽  
Pharmacological Properties ◽  
Medicinal Compounds ◽  
The World

Over the years, the world has become common to pandemic diseases in humans with lot of ailments and untreated infectious disorders. Most of the laboratories across the globe run in with under developed vaccines and drugs for many diseases for its procurement and prevention. But the bioavailability of the drug in the market is less reached due to high cost and etc. In the current situation, plant saps and its extracts are used to counteract with the pathogens based on the information in traditional medicine. Most of the phytochemical enriched herb, weed or plants available commonly are used for treatments of various diseases. One of the herbs found is Mollugo verticillata (commonly known as ‘green carpet weed’). It is commonly used in treating fever, aches and other various ailments and it shows promising activity in pharmacological properties due to the presence of phytoconstituents like terpenoids, saponins and flavonoids. Finally, the plant extract has enormous medicinal importance. This review is a collection of overall research work on Mollugo verticillata plant and their medicinal compounds present.

Nihilistic Thinking as the Self-Will of the Mind and the Projects of Its Overcoming

2020 ◽  
Vol 63 (10) ◽  
pp. 74-87
Author(s):  
Irina N. Sidorenko
Keyword(s):  
Significant Role ◽  
Current Situation ◽  
The Self ◽  
Spatial Perspective ◽  
The World ◽  
The Will ◽  
The Mind ◽  
Radical Transformation

 The author analyzes the conceptions of ontological nihilism in the works of S. Kierkegaard, F. Nietzsche, M. Heidegger, E. Jünger. On the basis of this analysis, violence is defined as a manifestation of nihilism, of the “will to nothingness” and hypertrophy of the self-will of man. The article demonstrates the importance of the problem of nihilism. The nihilistic thinking of modern man is expressed in the attitude toward a radical transformation of the world from the position of his “absolute” righteousness. The paradox of the current situation is that there is the reverse side of this transformative activity, when there is only the appearance of action and the dilution of responsibility. Confidence in the rightness of own views and beliefs increases the risk of the violent imposition of own vision of reality. Historical and philosophical reconstruction of the conceptions of nihilism allowed to reveal the following projects of its comprehension and resolution: (1) the project of “positing of values,” which consists in the transformation of the evaluation, which is understood as another perspective of positing values, leading to the affirmation of being; (2) the project of overcoming nihilism from the space of temporality, carried out through the resoluteness to accept the historicity of own existence; (3) the project of overcoming nihilism as the oblivion of being from the spatial perspective of the “line,” allowing to realize the “glimpse” of being. The author concludes that it is impossible to solve the problem of violence and its various forms of its manifestation without overcoming “ontological nihilism.” Significant role in solving the problem of ontological violence is assigned to philosophy as a critical and responsible form of thinking, which is capable to help a person to bear the burden of the world, to provide meanings and affirm being, as well as to unite people and resist the fundamentalist claims of exclusivity and rightness.

Regenerative flow pumps, blowers and compressors – A review

2021 ◽  
pp. 095765092110181
Author(s):  
M Sreekanth ◽  
R Sivakumar ◽  
M Sai Santosh Pavan Kumar ◽  
K Karunamurthy ◽  
MB Shyam Kumar ◽  
...  
Keyword(s):  
Quantitative Data ◽  
Research Work ◽  
Future Research ◽  
Performance Parameters ◽  
The World ◽  
Working Principle ◽  
Computational Fluid Dynamics Cfd ◽  
Specific Speed ◽  
Regenerative Flow ◽  
Product Description

This paper presents a detailed and objective review of regenerative flow turbomachines, namely pumps, blowers and compressors. Several aspects of turbomachines like design and operating parameters, working principle, flow behaviour, performance parameters and analytical and Computational Fluid Dynamics (CFD) related details have been reviewed and summarized. Experimental work has been put in perspective and the most useful results for optimized performance have been presented. Consolidated plots of specific speed-specific diameter have been plotted which can be helpful in the early stages of design. Industrial outlook involving details of suppliers from various parts of the world, their product description and applications too are included. Finally, future research work to be carried out to make these machines widespread is suggested. This review is targeted at designer engineers who would need quantitative data to work with.

scholarly journals Isolation, Structure Elucidation, and Biological Activity of a New Alkaloid from Zanthoxylum rhetsa

2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601
Author(s):  
Karsten Krohn ◽  
Stephan Cludius-Brandt ◽  
Barbara Schulz ◽  
Mambatta Sreelekha ◽  
Pottachola Mohamed Shafi
Keyword(s):  
Biological Activity ◽  
Carboxylic Acid ◽  
Medicinal Plant ◽  
Plant Extract ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Reduction Product ◽  
Pharmacological Properties ◽  
Evergreen Tree

Several biologically active alkaloids (1-4, 6), including a new quinazoline-6-carboxylic acid (1), were isolated from the medicinal plant Zanthoxylum rhetsa, an evergreen tree, native to subtropical areas. Whereas the pharmacological properties of the plant extract and single constituents have been widely tested, we now show that all of the metabolites have antialgal activities, all but 6 are antibacterial, and 6 and the reduction product 5 (derived from 4) are also antifungal.

Cornus mas: a review on traditional uses and pharmacological properties

2017 ◽  
Vol 14 (3) ◽  
Author(s):  
Fatemeh Hosseinpour-Jaghdani ◽  
Tahoora Shomali ◽  
Sajedeh Gholipour-Shahraki ◽  
Mohammad Rahimi-Madiseh ◽  
Mahmoud Rafieian-Kopaei
Keyword(s):  
Medicinal Plants ◽  
Pharmacological Properties ◽  
Traditional Uses ◽  
Cornus Mas ◽  
The World ◽  
Medicinal Properties

AbstractMedicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties.

The physicochemical and DNA binding studies of some medicinal compounds in solutions

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Abbas Khan ◽  
Naila ◽  
Muhammad Humayun ◽  
Muhammad Sufaid Khan ◽  
Luqman Ali Shah ◽  
...  
Keyword(s):  
Flow Behavior ◽  
Aqueous Media ◽  
Research Work ◽  
Binding Constants ◽  
Physicochemical Study ◽  
Solution Temperature ◽  
Binding Studies ◽  
Experimental Conditions ◽  
Medicinal Compounds ◽  
Association Behavior

Abstract To understand the expected mode of action, the physicochemical study on the solution properties of medicinal compounds and their interaction with deoxyribonucleic acid (DNA), under varying experimental conditions, is of prime importance. The present research work illustrates the physicochemical study and interaction of certain medicinal compounds such as; Levofloxacin, Ciprofloxacin, and Ibuprofen with DNA. Density, viscosity and surface tension measurements have been performed in order to determine, in a systematic manner, the physicochemical, volumetric and thermodynamic properties of these compounds; and most of these parameters have shown different behavior with varying concentration of solution, temperature of the medium and chemical nature/structure of the compound. In addition, these drugs showed a spontaneous surface-active and association behavior in aqueous solutions. The flow behavior, surface properties, volumetric behavior and solute–solvent interaction of these drugs were prominently influenced by experimental variables and addition of DNA to their solutions. UV–Visible spectroscopy was also used to examine the interaction of these drugs with DNA in aqueous media in detail. Calculated values of binding constants (Kb) for all complexes of drug-DNA are positive, indicating a fruitful binding process. It is seen that a smaller Kb value reflects weaker binding of the drug with DNA and vise versa. Due to the difference in the chemical structure of drugs the values of binding constant are different for various drug-DNA complexes and follow the order Kb(Levofloxacin-DNA) > Kb(Ciprofloxacin-DNA) > Kb(Ibuprofen-DNA). On the basis of spectral changes and Kb it can be said that the binding of all these drugs with DNA may be of physicochemical nature and the dominating binding force be of hydrogen bonding between oxygen of drugs and hydrogen of DNA units and the drug having more oxygen atoms showed stronger binding ability. The data further suggest a limited possibility of chemical type attachment of these drugs with DNA.

Text Writing Using Air Gestures for People With Limited Hand Motor Skills

2020 ◽  
Author(s):  
Michele Ermidoro ◽  
Andrea Vitali ◽  
Fabio Previdi ◽  
Caterina Rizzi
Keyword(s):  
Mobile Devices ◽  
Motor Skills ◽  
Specific Interaction ◽  
Research Work ◽  
Interaction Style ◽  
The World ◽  
Software Modules ◽  
Ict Tools ◽  
Brain Stroke ◽  
Text Writing

Abstract Mobile devices and laptops are the main ICT tools to exchange information among people in the world. All the applications are designed by following a specific interaction style based either touchscreen or mouse and keyboard, which can be performed only with detailed movements of hands and fingers. Traditional interaction becomes difficult for elderly who have diseases limiting the hand motor skills, such as arthritis and brain stroke. The use of simple air gestures can be adopted as alternative interaction style to interact with smartphones, tablets and laptops. The aim of this research work is the development of an application that allows text writing using air gestures for people with limited hand motor skills. The application embeds several computer vision algorithms and convolutional neural networks software modules to detect and drawn alphanumeric characters and recognizing them using both mobile devices and laptops. The preliminary results obtained show that the approach is robust, and it can easily detect the alphanumeric characters written with the movement of the wrist.

Dehumanizing to Demonizing: Critical Discourse Analysis of George Bush’s Speeches for Exploring the Influence of Dehumanizing Metaphor in Political Discourse

2021 ◽  
pp. 154-168
Keyword(s):  
Discourse Analysis ◽  
Critical Discourse Analysis ◽  
Postcolonial Theory ◽  
Research Work ◽  
Critical Discourse ◽  
George Bush ◽  
Sense Of Security ◽  
The Us ◽  
The World ◽  
Sense Of Justice

To legitimize US invasion of Iraq, Bush fabricated fake intelligence reports, and depended solely on propaganda; he manipulated language in a well-calculated manner; most particularly, the metaphors chosen and devised for his speeches were such that convinced the US citizens about the legitimacy of the invasion, elicited financial support of the European allies and moral support of the majority of the world community. This research work used discourse analysis to study the metaphors that were used by George Bush in the speeches he made on 8 different occasions, and the theoretical framework used in it is the combination of critical discourse analysis CDA with postcolonial theory concept of orientalism.It utilized both qualitative and quantitative data collection tools.It found that most of the task was accomplished through the linguistic manipulation in the shape of metaphor used to dehumanize the enemy, which first made the US citizens feel as victims to the jealousy of rogue Muslim states for intending to completely annihilate them; then, it made appeal to their sense of justice, sense of security, and right to self-defense. By grouping the world citizens into Us and Them groups, the innocent, peace-loving and the war-mongers, the angels and the devils, and then by placing themselves and the rest of the world among the first group and placing the powerfulMuslims states among the second group, the US exploited the feelings and thoughts of all. Despite the UN and the rest of the world having come to know the sheer lies of the US now, the US still has managed to flog a dead horse and blind-fold majority of the world through this linguistic manipulation in the form of using dehumanizing metaphors

Gymnanthemum coloratum: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties -

2020 ◽  
Vol 10 (5) ◽  
pp. 196-204
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Skin Diseases ◽  
Pharmacological Properties ◽  
Sources Of Information ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Plant Parts ◽  
Aerial Parts ◽  
Cytotoxicity Activities

Gymnanthemum coloratum is a shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. The current study is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of G. coloratum. Literature on pharmacological properties, phytochemistry and medicinal uses of G. coloratum was obtained from numerous internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. The current study showed that G. coloratum is used as an anthelmintic, and traditional medicine for reproductive problems, schistosomiasis, liver diseases, sexually transmitted infections, diabetes, sores and wounds, respiratory problems, malaria, skin diseases, fever and gastro-intestinal problems. Ethnopharmacological research identified glaucolides, lactones, amino acids, essential oils, alkaloids, anthocyanins, cardenolids, coumarins, flavonoids, glycosides, leucoanthocyanins, phenols, quinones, reducing sugars, saponins, steroids, tannins, terpenoids and triterpenes from the aerial parts, leaves, roots and stems of G. coloratum. The aerial parts, leaves, roots and whole plant parts of G. coloratum and compounds isolated from the species exhibited anthelmintic, antimicrobial, anti-Blastocystis, anti-inflammatory, anti-sickling, insecticidal and larvicidal, antiplasmodial, antimalarial, antioxidant, antiproliferative, anti-Toxoplasma, hypoglycaemic and antidiabetic and cytotoxicity activities. Gymnanthemum coloratum should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

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