scholarly journals Complete Review of Ayurvedic Management of Raktapradar w.s.r. to Brihatrayi and Laghutrayi

2021 ◽  
pp. 51-58
Author(s):  
Ashwini Karache S ◽  
Seema Mehere
Keyword(s):  
Side Effects ◽  
Hormonal Therapy ◽  
Modern Science ◽  
Modern Medicine ◽  
Menstrual Bleeding ◽  
Bleeding Disorders ◽  
Ovulatory Cycle ◽  
Antifibrinolytic Agents ◽  
Excessive Bleeding ◽  
Hormonal Therapies

Raktapradar in Ayurveda is characterized by excessive or prolonged menstruation with or without intermenstrual bleeding, which is one of the most common bleeding disorders in women. Excessive bleeding from uterus either at the time of menses or in intermenstrual time is considered as Asrigdara or Raktapradar in Ayurveda. Normal menstrual bleeding including ovulation or more specifically the organized sequence of endocrine signals that characterizes the ovulatory cycle, menses regularities, predictability & consistency. It is most basic concept that control the endometrial cycle, the volume & the duration of menstrual flow. Cyclic regular menstrual bleeding which is excessive in amount & duration considered as Menorrhagia. Raktapradar can be correlated with menorrhagia. As per modern science, menorrhagia is defined as cyclic regular bleeding which is excessive in amount (>80ml) or duration (>7 days) or both. It is considered as one of the commonest leading gynecological problem. In modern medicine haemostatic, analgesic and hormonal therapies are advised for Menorrhagia, which includes hormonal therapy, antiprostaglandins & antifibrinolytic agents. These have not proven their definitive efficacy in spite of high costs; their side effects have led to hormonal imbalances hence it is need of time to have an integrated and comprehensive therapeutic intervention in Ayurveda to prevent recurrence& would overcome the modern medicine limitations. Many herbal & herbo-mineral preparations, Shodhan & Shaman Chikits as per Rugnabal are mentioned in Ayurveda to cure Raktapradar and related symptoms which can be used as per Anubandha Dosha and Lakshana.

scholarly journals Case-based discussion on the implications of exogenous estrogens in hemostasis and thrombosis: the hematologist’s view

Hematology ◽  
2019 ◽  
Vol 2019 (1) ◽  
pp. 152-157
Author(s):  
Margaret V. Ragni
Keyword(s):  
Hormonal Therapy ◽  
Postpartum Hemorrhage ◽  
Heavy Menstrual Bleeding ◽  
Menstrual Bleeding ◽  
Current Therapy ◽  
Bleeding Disorders ◽  
Psychological Burden ◽  
Thrombosis Risk ◽  
Data Limitations ◽  
Case Based

Abstract In the childbearing years, hormonal therapy or hormonal changes in the menstrual cycle or the puerperium may be complicated by bleeding or thrombosis; however, among women with congenital disorders of hemostasis and thrombosis, the risk of bleeding or thrombosis may be increased. In women with congenital bleeding disorders, heavy menstrual bleeding is the most common bleeding symptom, and postpartum hemorrhage occurs despite treatment. Given the limitations of current therapy and the associated medical and psychological burden in women with bleeding disorders, better treatment approaches are needed to improve health outcomes and quality of life. In women with congenital thrombotic disorders, thromboembolism may complicate exogenous hormonal therapy and endogenous hormonal change during pregnancy and procedures, but risk differs by type of thrombophilia, procedure, time at risk, and thrombosis risk factors, all of which affect management. In this article, I shall consider a case-based discussion of current issues in women with congenital bleeding and clotting disorders, including heavy menstrual bleeding in a woman with VWD, postpartum hemorrhage risk in VWD, and thrombosis risk with oocyte retrieval in a woman with factor V Leiden and past thromboembolism. The goals are to review bleeding or thrombosis risk in these cases, current data, limitations of current treatment guidelines, and areas for future study.

Incidence of Hypertension Among Children Treated With Adrenocorticotropic Hormone (ACTH) or Prednisolone for Infantile Spasms

2019 ◽  
Vol 35 (3) ◽  
pp. 215-220 ◽  
Author(s):  
Laurel McGarry ◽  
Ricka Messer ◽  
Melanie Cree-Green ◽  
Krista Ray ◽  
Kelly Knupp
Keyword(s):  
Side Effects ◽  
Hormonal Therapy ◽  
Adrenocorticotropic Hormone ◽  
Retrospective Chart Review ◽  
Infantile Spasms ◽  
Common Side Effect ◽  
P 75 ◽  
Systemic Side Effects ◽  
Missed Diagnosis ◽  
Hormonal Therapies

Children with infantile spasms are often treated with hormonal therapies including adrenocorticotropic hormone (ACTH) and prednisolone. These have numerous systemic side effects including hypertension and, rarely, fatal cardiomyopathy; however, the incidence of these side effects has not been well described. This study aims to quantify the incidence and short-term sequelae of hypertension in this population. A retrospective chart review was performed at a single institution. Children 2 months to 2 years old with newly diagnosed infantile spasms treated from 2013 to 2017 were included. Variables collected included age, sex, etiology and treatment of infantile spasms, documented or missed diagnosis of hypertension, treatment of hypertension, echocardiogram results, referrals for hypertension, and persistence of hypertension 2 to 4 months after treatment. Analyses included descriptive statistics with percentiles, means, and medians. Differences between groups were assessed using Fisher exact tests. Hypertension occurred in 34/77 children (44%) during treatment with ACTH and 4/11 children (36%) during treatment with prednisolone. No child developed hypertension during treatment with nonhormonal therapies. The incidence of hypertension between ACTH and prednisolone groups was not significantly different ( P = .75). The incidence of hypertension was significantly higher in the ACTH and prednisolone groups compared to the nonhormonal group ( P < .001 for each). Sixteen children received echocardiograms, with no cases of cardiomyopathy. Two children had persistent hypertension at 2 months after discontinuation of hormonal therapy. Hypertension is a very common side effect of hormonal therapy for infantile spasms; however, few developed long-term hypertension and none developed cardiomyopathy. Further study is needed to determine the role of antihypertensive treatment for hormone-related hypertension.

A Critical Review on Tamaka Shwasa (Bronchial Asthma) - An Ayurvedic View

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Sandip R. Baheti ◽  
Deepa Sharma ◽  
Saroj Devi ◽  
Amit Rai
Keyword(s):  
Bronchial Asthma ◽  
Inflammatory Disease ◽  
Critical Review ◽  
Modern Science ◽  
Modern Medicine ◽  
Chronic Inflammatory Disease ◽  
The Body ◽  
Natural Immunity ◽  
Shortness Of Breath ◽  
Asthma Symptoms

Difficulty in breathing or shortness of breath may be simply termed as Shwasa (Asthma), As per Ayurveda, Shwasa is mainly caused by the Vata and Kapha Doshas. Shwasa is broadly classified into five types in Maha Shwasa (Dyspnoea major), Urdhawa Shwasa (Expiratory Dyspnoea), Chinna Shwasa (Chyne-stroke respiration), Kshudra Shwasa (Dyspnoea minor), Tamaka Shwasa (Bronchial Asthma). In modern science Tamaka Shwasa can be correlated with Asthma, Asthma which is a chronic inflammatory disease of airway. In modern medicine there is no cure for Asthma, symptoms can typically be improved. In Ayurveda, Asthma can be effectively and safely manage the condition without inducing any drug dependency where Pachakarma procedures and use of internal medication detoxifies the body, provides nutrition and increases the elasticity of lung tissue it also develops natural immunity of the body thus decreasing episodic recurrence of the disease.

Use hormonal contraception in women with overweight

2017 ◽  
pp. 120-122
Author(s):  
N.V. Avramenko ◽  
◽  
I.B. Gridina ◽  
Keyword(s):  
Side Effects ◽  
Reproductive Health ◽  
Key Words ◽  
Mucous Membrane ◽  
Clinical Supervision ◽  
Hormonal Contraception ◽  
Negative Influence ◽  
Modern Medicine ◽  
Excessive Weight ◽  
Important Direction

Maintenance of reproductive health and decision of problem of safe contraception women with excessive weight have the issue of the day of present time and it is confessed by important direction of modern medicine. The objective: to define influence of hormonal contraception on the mucous membrane of neck of uterus for women with surplus mass of body. Patients and methods. In 90 women with excessive weight influence of hormonal contraception is studied on the mucous membrane of neck of uterus. Results. It is set that a modern hormonal contraception does not have a negative influence on the state of mucous membrane of neck of uterus for women with surplus mass of body. Conclusion. Women with excessive weight and can effectively and safely to use a modern hormonal contraception. But it is necessary to carry out a clinical supervision for the step of that additional elucidations are possible about the features of application of hormonal contraception for patients with excessive mass of body. Key words: contraception, overweight, side effects.

Side effects of hormonal therapy with tamoxifen

2018 ◽  
pp. 16-22
Author(s):  
E.I. Kovalenko ◽  
L.V. Manzyuk ◽  
I.B. Kononenko ◽  
O.P. Grebennikova
Keyword(s):  
Side Effects ◽  
Hormonal Therapy

scholarly journals Research, biomedicine and Ayurveda: From evidence-based medicine to evidence-informed healthcare

2021 ◽  
pp. 01-04
Author(s):  
Sarika Chaturvedi ◽  
Nandini Kumar ◽  
Girish Tillu ◽  
Bhushan Patwardhan
Keyword(s):  
Traditional Medicine ◽  
Effective Treatment ◽  
Evidence Based Medicine ◽  
Modern Science ◽  
Modern Medicine ◽  
Evidence Based ◽  
Appropriate Use ◽  
The Public ◽  
Based Medicine ◽  
Tools And Methods

As the search for effective treatment for Covid-19 intensifies, traditional medicine systems are receiving increasing attention from researchers as well as the public. While scientific rigour is non-negotiable, there remain fundamental issues to be addressed when bringing evidence from traditional systems. Here we examine some of these issues pertaining to Ayurveda and the underlying philosophical underpinnings, and suggest potential ways to move forward. We find an ability to emerge from the cage of “biomedicalism” and its foundational reductionism essential for appropriate research in Ayurveda. We caution against pursuing research in Ayurveda by just mimicking modern medicine and highlight the need for appropriate use of modern science tools and methods to understand Ayurveda and explore its potential for healthcare. We emphasise the need and potential for transdisciplinary research in Ayurveda. A balance between evidence-based medicine and evidence-informed healthcare is required.

scholarly journals To study the role of guduchyadi kashaya on viral diseases.

2020 ◽  
Vol 8 (05) ◽  
Author(s):  
Akshay Vaidya
Keyword(s):  
Wound Healing ◽  
Side Effects ◽  
Medicinal Plants ◽  
Broad Spectrum ◽  
Viral Infections ◽  
Modern Science ◽  
Viral Diseases ◽  
Diverse Group ◽  
Herbal Extracts

Viral infections remain major “worldwide” cause of morbidity and mortality.  Herbal extracts or wholesome drugs have been in use for medicinal purposes since ancient time and are known for their antiviral properties and more tolerable side effects. Thus, naturally based pharmacotherapy is a proper alternative for treating viral diseases. Hence this article describes potential antiviral properties of medicinal plants against diverse group of viruses and suggests screening the potential of plants possessing broad spectrum anti-viral effects against viral diseases. Guduchyadi Kwath is a polyherb ayurvedic preparation useful in various diseases. It is useful in pitta vikar, shleshma vikar, Jwara, Chardi, Daha, Trushna, and Agnimandya1. According to modern science it showed anti-inflammatory, antioxidant, antibacterial, antiviral, antimalarial, hepatoprotective, wound healing and immune-modulatory action. The study is aim to the effect of “Guduchyadi kashaya” on viral diseases.

Effect Of DDAVP In Patients With Von Willebrand’s Disease And Hemophilia A

1981 ◽  
Author(s):  
A I Warrier ◽  
C Hillman ◽  
J M Lusher
Keyword(s):  
Side Effects ◽  
Factor Viii ◽  
Hemophilia A ◽  
Blood Components ◽  
Excessive Bleeding ◽  
Von Willebrand's Disease ◽  
Von Willebrand’S Disease ◽  
Crossed Immunoelectrophoresis ◽  
Transient Improvement ◽  
The U.S

European investigators have reported on the efficacy of l-deamino-9-D-arginine vasopressin (DDAVP) in von Willebrand’s disease (vWD) and mild hemophilia A. We have thus evaluated the effects of a single intranasal dose of DDAVP (200ugm of the more dilute form available in the U.S.), in 12 individuals with vWD and in 4 with moderate hemophilia A. Crossed immunoelectrophoresis of VIII: RAg demonstrated normal electrophoretic mobility in each of the vWD subjects. Components of the factor VIII system (VIII: C, VIII: RAg, VIII: R Cof.) were assayed pre - and 90 and 180 minutes post- DDAVP. Each of 11 subjects with mild or moderate vWD had an increase in VIII: C activity (avg. 2X increase), 8 of 11 had an increase in VIII: R Cof, and 9 of 11 had an increase in VIII: RAg. The twelfth vWD subject, who had severe vWD, had no rise in any of these components. Of 4 vWD subjects who had pre- and post-DDAVP template bleeding times (BT) performed, the only one who had a prolonged baseline BT showed a normal BT 90 minutes post-DDAVP. One vWD subject, in whom we had documented an increase in all F. VIII components after DDAVP, later underwent dental extractions 90 minutes after DDAVP. No excessive bleeding was noted. Four individuals with moderate hemophilia A (baseline VIII: C values of 0.02-0.10 u/ml) were also studied. Three had a rise in all components of the factor VIII system post-DDAVP while the fourth did not. No undesirable side effects were noted in any of the 16 subjects who received DDAVP. We conclude that even the more dilute form of DDAVP available in the U.S., when given intranasally, results in transient improvement in selected individuals with vWD or moderate hemophilia A. This drug thus warrants further study as an alternative to blood components in the management of vWD, as well as in mild and moderate hemophilia A.

scholarly journals Hypnosis and Hypnotherapy: Emerging of Science-Based Hypnosis

2020 ◽  
Author(s):  
Cengiz Mordeniz
Keyword(s):  
Side Effects ◽  
Modern Medicine ◽  
Holistic Medicine ◽  
Drug Injection

Hypnosis, which has been used for centuries in different forms, has to be reevaluated in the light of modern medicine and science by biological, psychological, sociological and spiritual approach. Hypnosis has been regaining its popularity in the trend of personalized and holistic medicine without any drug, injection or side effects.

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