Biomedical researcher Laurie Locascio tapped to lead NIST

2021 ◽  
pp. 12-12
Author(s):  
Britt E. Erickson
Keyword(s):  
Biomedical Researcher

scholarly journals Gender Imbalance in the Editorial Activities of a Researcher-led Journal

2021 ◽  
Author(s):  
Tal Seidel Malkinson ◽  
Devin B. Terhune ◽  
Mathew Kollamkulam ◽  
Maria J. Guerreiro ◽  
Dani S. Bassett ◽  
...  
Keyword(s):  
Gender Disparity ◽  
Gender Disparities ◽  
Editorial Process ◽  
Gender Imbalance ◽  
Women Editors ◽  
Scientific Enterprise ◽  
Biomedical Researcher ◽  
Scientific Disciplines ◽  
Editorial Decision ◽  
Editorial Decisions

Editorial decision-making is a fundamental element of the scientific enterprise. We examined whether contributions to editorial decisions at various stages of the publication process is subject to gender disparity, based on analytics collected by the biomedical researcher-led journal eLife. Despite efforts to increase women representation, the board of reviewing editors (BRE) was men-dominant (69%). Moreover, authors suggested more men from the BRE pool, even after correcting for men's numerical over-representation. Although women editors were proportionally involved in the initial editorial process, they were under-engaged in editorial activities involving reviewers and authors. Additionally, converging evidence showed gender homophily in manuscripts assignment, such that men Senior Editors over-engaged men Reviewing Editors. This tendency was stronger in more gender-balanced scientific disciplines. Together, our findings confirm that gender disparities exist along the editorial process and suggest that merely increasing the proportion of women might not be sufficient to eliminate this bias.

scholarly journals Antisense-based therapy for the treatment of spinal muscular atrophy

2012 ◽  
Vol 199 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Frank Rigo ◽  
Yimin Hua ◽  
Adrian R. Krainer ◽  
C. Frank Bennett
Keyword(s):  
Spinal Muscular Atrophy ◽  
Neuromuscular Disease ◽  
Muscular Atrophy ◽  
Biomedical Researcher ◽  
The Past

One of the greatest thrills a biomedical researcher may experience is seeing the product of many years of dedicated effort finally make its way to the patient. As a team, we have worked for the past eight years to discover a drug that could treat a devastating childhood neuromuscular disease, spinal muscular atrophy (SMA). Here, we describe the journey that has led to a promising drug based on the biology underlying the disease.

scholarly journals A network module for the Perseus software for computational proteomics facilitates proteome interaction graph analysis

2018 ◽  
Author(s):  
Jan Rudolph ◽  
Cox Jürgen
Keyword(s):  
Data Analysis ◽  
Network Analysis ◽  
Posttranslational Modifications ◽  
Affinity Purification ◽  
Network Module ◽  
Proteomics Data ◽  
Biomedical Researcher ◽  
Large Numbers ◽  
Statistical Analysis Method ◽  
Proteomics Data Analysis

ABSTRACTProteomics data analysis strongly benefits from not studying single proteins in isolation but taking their multivariate interdependence into account. We introduce PerseusNet, the new Perseus network module for the biological analysis of proteomics data. Proteomics is commonly used to generate networks, e.g. with affinity purification experiments, but networks are also used to explore proteomics data. PerseusNet supports the biomedical researcher for both modes of data analysis with a multitude of activities. For affinity purification, a volcano plot-based statistical analysis method for network generation is featured which is scalable to large numbers of baits. For posttranslational modifications of proteins, such as phosphorylation, a collection of dedicated network analysis tools helps elucidating cellular signaling events. Co-expression network analysis of proteomics data adopts established tools from transcriptome co-expression analysis. PerseusNet is extensible through a plug-in architecture in a multi-lingual way, integrating analyses in C#, Python and R and is freely available at http://www.perseus-framework.org.

scholarly journals Basic antidepressant research: a brief assay on how to justify your alpha

Bionatura ◽  
2019 ◽  
Vol 02 (Bionatura Conference Serie) ◽  
Author(s):  
Cilene Lino de Oliveira
Keyword(s):  
Hypothesis Testing ◽  
Risk Of Bias ◽  
Biomedical Researcher ◽  
Traditional Use ◽  
P Values

Antidepressant research seems under risk of bias and poor reproducibility. Recent debates brought the use of the p values in hypothesis testing to the center of a reproducibility crisis. In basic biomedicine, the use of p values has been justified by tradition instead of reasoning. Here, a biomedical researcher commented concerns with the traditional use of the p values in basic antidepressant research and discussed the missing pieces limiting the plausible justifications to their use in the field.

scholarly journals A pocket guide to electronic laboratory notebooks in the academic life sciences

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2 ◽  
Author(s):  
Ulrich Dirnagl ◽  
Ingo Przesdzing
Keyword(s):  
Practical Knowledge ◽  
Life Sciences ◽  
Academic Research ◽  
Modern Science ◽  
Academic Life ◽  
Laboratory Notebook ◽  
Biomedical Researcher ◽  
Electronic Laboratory Notebook ◽  
Active Research

Every professional doing active research in the life sciences is required to keep a laboratory notebook. However, while science has changed dramatically over the last centuries, laboratory notebooks have remained essentially unchanged since pre-modern science. We argue that the implementation of electronic laboratory notebooks (eLN) in academic research is overdue, and we provide researchers and their institutions with the background and practical knowledge to select and initiate the implementation of an eLN in their laboratories. In addition, we present data from surveying biomedical researchers and technicians regarding which hypothetical features and functionalities they hope to see implemented in an eLN, and which ones they regard as less important. We also present data on acceptance and satisfaction of those who have recently switched from paper laboratory notebook to an eLN.  We thus provide answers to the following questions: What does an electronic laboratory notebook afford a biomedical researcher, what does it require, and how should one go about implementing it?

The Biomedical Researcher and Subpoenas: Judicial Protection of Confidential Medical Data

1986 ◽  
Vol 12 (3-4) ◽  
pp. 405-421
Author(s):  
Angela R. Holder
Keyword(s):  
Medical Data ◽  
Expert Witnesses ◽  
Biomedical Researcher ◽  
Medical Researchers ◽  
Judicial Protection

AbstractAn increasing number of medical researchers are being subpoenaed to testify or to supply records in cases in which they have not agreed to become involved as expert witnesses. The researchers’ published works are alleged to have formed the basis of the opinions of physicians testifying as expert witnesses in these cases. Although the courts usually protect confidential medical data, the considerable burden of quashing these subpoenas is still imposed upon researchers and their universities. This Article argues that courts should protect these research records from subpoenas.

scholarly journals Study of Plantar Pressure Distribution

2018 ◽  
Vol 237 ◽  
pp. 01016
Author(s):  
Chun Kit Ang ◽  
Mahmud Iwan Solihin ◽  
Weng Jun Chan ◽  
Yien Yien Ong
Keyword(s):  
Young Adults ◽  
Pressure Distribution ◽  
Plantar Pressure ◽  
Flat Surface ◽  
Orthotic Devices ◽  
Free Standing ◽  
Inclined Plane ◽  
Biomedical Researcher ◽  
Plantar Pressure Distribution ◽  
First Time

Every region of foot is not equally divided in terms of plantar pressure distribution (PPD) during free standing. This paper is focusing on studying PPD on flat plane and inclined plane and the results obtained from this study may contribute to biomedical researcher in designing orthotic devices. 24 healthy young adults age ranging from 19 to 24 years old and weigh between 50 to 80 kg were invited for experiments purpose. Six regions of both feet were measured which were hallux, medial forefoot, central forefoot, lateral forefoot, lateral midfoot and hindfoot. Remarkable differences were seen in the result as right foot exerted more pressure generally in every region of the foot as to compared with left foot respectively. This is true especially for region such as hallux, medial forefoot and lateral forefoot. On a flat surface, PPD on the hindfoot is the highest. However, at an elevation of 25°, test subjects began to shift their PPD to forefoot regions. While studies of PPD are common, this study provides a new insight for the first time into PPD while standing on different angle of walking plane.

scholarly journals Assessing the consequences of decentralizing biomedical research

2019 ◽  
Vol 6 (1) ◽  
pp. 205395171985385
Author(s):  
Brian M Bot ◽  
John T Wilbanks ◽  
Lara M Mangravite
Keyword(s):  
Biomedical Research ◽  
Research Process ◽  
Unintended Consequences ◽  
Biomedical Data ◽  
Data Governance ◽  
Biomedical Researcher ◽  
Implementation Evaluation ◽  
Effective Implementation ◽  
Technological Advances ◽  
Types Of Information

Advancements in technology are shifting the ways that biomedical data are collected, managed, and used. The pervasiveness of connected devices is expanding the types of information that are defined as ‘health data.’ Additionally, cloud-based mechanisms for data collection and distribution are shifting biomedical research away from traditional infrastructure towards a more distributed and interconnected ecosystem. This shift provides an opportunity for us to reimagine the roles of scientists and participants in health research, with the potential to more meaningfully engage in partnership across the research process. At the same time, these emerging practices present a potential to expose research participants to unanticipated and unintended consequences. Social norms and policy can help to mitigate these risks, but their development is often slow relative to the pace of technological advances and, as such, they can become reactive rather than prospective. As an alternative, the integrated development of data governance structures within technological advancements, supports their effective implementation, evaluation and evolution in a manner that can balance the benefits and risks of biomedical researcher in a decentralized ecosystem.

Teaching Hospitals Today and the Challenge for Excellence

PEDIATRICS ◽  
1983 ◽  
Vol 71 (6) ◽  
pp. 978-979
Author(s):  
JOSEPH W. ST. GEME
Keyword(s):  
Hospital Care ◽  
Academic Medical Centers ◽  
Teaching Hospitals ◽  
Biomedical Researcher ◽  
Academic Leaders ◽  
Teaching Institution ◽  
Medical Centers ◽  
Academic Medical ◽  
Secondary Hospital ◽  
Administrative Leader

The contemporary pediatric chairman exists in an extraordinary professional milieu. The challenge for academic leaders in this deacde becomes more rigorous with each passing day. No longer will the traditional attributes of teacher, clinician, and biomedical researcher suffice. The chairman must also become a competitive academic-administrative leader with additional skills in personnel management and entrepreneurial business pursuits. At the same time, the arena in which he or she toils, the teaching hospital, has become an economic battle-ground. Competition for patient population and teaching material in our academic medical centers is intense. Can we meet it? Nonteaching community hospitals surround every teaching institution. These hospitals provide primary and secondary hospital care with much less fuss.

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