The Frequency of Normal Variations of Oral Mucosa in Patients  Referred to Qazvin School of Dentistry, Spring, 2015

Background: Oral mucosa which covers inside of the mouth is a complex structure that has been adapted for its particular function and anatomical location. Some oral conditions, despite their different physical features, are not pathological; rather, they are considered normal such as Linea Alba, Parotid Papilla, Geographic Tongue and Fissured Tongue. Materials and Methods: in this cross-sectional study 692 patients were registered through clinical examination and fulfillment of predesigned questionnaire. Diagnostic criteria in this study included the normal changes of the oral mucosa (including geographic tongue, fissured tongue, scalloped tongue, parotid papilla, palatal and mandibular torus, Lina Alba, frenal tag, leukoedema, Fordyce granules). Results: 692 people with an average age of 35years participated in this study. The overall sum of oral cavity normal variations was 806, 542 cases of which were female and 264 cases male. Conclusion: In this study 692 patients were examined by specialists; 494 cases, a sum of 71% had oral cavity normal variations. Linea Alba had the highest frequency among normal variations.

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Knowledge Assessment among the Fourth and Fifth Year Students on the Potentially Malignant Lesions of Oral Cavity

Balkan Journal of Dental Medicine ◽

10.2478/bjdm-2020-0003 ◽

2020 ◽

Vol 24 (1) ◽

pp. 14-20

Author(s):

Sanja Hadžić ◽

Mirjana Gojkov-Vukelić ◽

Enes Pašić ◽

Arma Muharemović ◽

Indira Mujić Jahić

Keyword(s):

Oral Cancer ◽

Oral Cavity ◽

Oral Mucosa ◽

Cross Sectional Study ◽

Self Assessment ◽

Cross Sectional ◽

Increased Risk ◽

Potentially Malignant ◽

Malignant Lesions ◽

The Difference

SummaryBackground/Aim: Potentially malignant oral lesions (PMOL) are lesions that have an increased risk of malignant transformation concerning healthy oral mucosa. This research aimed to assess the knowledge of students of final years of study on the potentially malignant lesions of the oral cavity.Material and Methods: 120 students of the fourth and fifth years of study participated in this research,60 respondents were fourth-year students, 60 respondents were fifth-year students. All of the respondents signed informed consent.According to the type of research, this is a cross-sectional study which was conducted by completing a 15-item questionnaire. The results were statistically analyzed and processed in the SPSS Statistics 21.0 program.Results: The results indicate that during the clinical examination the fourth and fifth-year students examine the oral mucosa as well. 61% of the students find themselves poorly informed on the PMOL. In the fourth year of study, only 5,5% of students responded that they were well informed, while in the fifth year that number totaled 28,5%. When knowledge self-assessment is concerned the difference has shown itself to be statistically significant between the fourth and fifth-year students. When asked what knowledge on the prevention of oral cancer they expect to receive during their studies, 78% of the students expected more knowledge than at that moment – 36% of which were fifth-year students, and 42% were fourth-year students.Conclusions: Even though the oral cavity is easily accessible to examination, the discovery of oral cancer occurs quite late. Ours, as well as results of other studies, impose the need for better theoretical and practical education of the students.

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Assessment of the gustatory function in patients with advanced oral cavity and oropharyngeal cancer

CoDAS ◽

10.1590/2317-1782/20202019122 ◽

2020 ◽

Vol 32 (6) ◽

Author(s):

Maria Deluana da Cunha ◽

Danielle de Sousa Terto ◽

Jacob Diniz ◽

Roberta Borba Assis

Keyword(s):

Oral Cavity ◽

Oropharyngeal Cancer ◽

Bitter Taste ◽

Cross Sectional Study ◽

Anatomical Location ◽

Cross Sectional ◽

Oncological Treatment ◽

Neck Tumors ◽

Gustatory Function ◽

Hearing Assessment

Abstract: Purpose: The changes in gustatory function resulting from oncological treatment occur mainly after radiotherapy. However, the head and neck tumors, because of the anatomical location of the lesion, can themselves trigger significant changes in the feeding-related functions - including taste. To assess the gustatory function in patients diagnosed with advanced oral cavity and oropharyngeal cancer. Method: This descriptive cross-sectional study comprised 31 individuals with advanced oral cavity and oropharyngeal cancer, referred for oncological treatment with radiotherapy, either alone or in combination with chemotherapy. The “taste strips” test was applied; it consists of inserting solutions with four different concentrations each for salty, sweet, and sour tastes, and three concentrations for the bitter taste, on the tongue. Results: Most of the individuals were diagnosed with oropharyngeal cancer. Approximately half of the sample already had taste-related complaints, and more than 80%, swallowing-related complaints. The overall frequency of hypogeusia was 38.7%, in which the bitter taste stood out in its isolated assessment. The association of change in gustatory function proved to be significant in patients in stage T4. Conclusion: The decrease in gustatory function in individuals with oral cavity and oropharyngeal cancer was evidenced in this study, especially when associated with tumors in stage T4. Regarding feeding, most of them reported complaints of dysphagia, suggesting the importance of the speech-language-hearing assessment and follow-up, even before the oncological treatment, to minimize the risks of dysphagia.

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Maxillofacial injuries among Brazilian children and adolescents victims of traffic accidents

RGO - Revista Gaúcha de Odontologia ◽

10.1590/1981-863720150001000032952 ◽

2015 ◽

Vol 63 (1) ◽

pp. 19-24 ◽

Cited By ~ 1

Author(s):

Laís Gonzaga de FARIAS ◽

Rebeca Valeska Soares PEREIRA ◽

Lorenna Mendes Temóteo BRANDT ◽

Thaliny Batista Sarmento de OLIVEIRA ◽

Alidianne Fábia Cabral XAVIER ◽

...

Keyword(s):

Oral Cavity ◽

Children And Adolescents ◽

Traffic Accidents ◽

Young Male ◽

Cross Sectional Study ◽

Body Region ◽

Maxillofacial Injuries ◽

Chi Square ◽

Cross Sectional ◽

Chi Square Test

OBJECTIVE: To analyze the prevalence of morbidity due to traffic accidents in children and adolescents and its relationship with maxillofacial injuries in the city of Campina Grande, Paraíba, Brazil. METHODS: This cross-sectional study analyzed 533 forensic reports of individuals aged 0-19 years, victims of external causes in Campina Grande, Brazil, in 2013. Data were collected through a form containing variables sex, age, day of week, time, type of traffic accident, injured body region, presence of fractures, maxillofacial and oral cavity injuries. The Statistical Package for Social Sciences software (SPSS) was used for data analysis. Prevalence ratios and confidence intervals at 95% were estimated with the chi-square test. RESULTS: There was predominance of males (75.0%) aged 15-19 years (65.0%), with association between sex and occurrence of traffic accidents (p <0.001). The afternoon shift recorded 36.7% of cases of accidents involving motorcyclists (55.0%). In 25.0% of cases, there were injuries on the head and 26.7% on the face. Head and face injuries were observed in 10.0% of patients, while maxillofacial and oral cavity injuries were present in 21.7% and 6.7%, respectively. There was an association between occurrence of accident and face injuries (p = 0.009). CONCLUSION: Traffic accidents affect mostly young male individuals, causing multiple injuries in different body areas, including maxillofacial and oral cavity injuries.

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Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens

Oral Diseases ◽

10.1111/odi.12924 ◽

2018 ◽

Vol 24 (8) ◽

pp. 1484-1491 ◽

Cited By ~ 10

Author(s):

Thalita S. Tavares ◽

Daniela P. Meirelles ◽

Maria Cássia F. de Aguiar ◽

Patrícia C. Caldeira

Keyword(s):

Oral Mucosa ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Pigmented Lesions

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High prevalent human papillomavirus infections of the oral cavity of asymptomatic HIV-positive men

BMC Infectious Diseases ◽

10.1186/s12879-019-4677-9 ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Rocío Méndez-Martínez ◽

Silvia Maldonado-Frías ◽

Salvador Vázquez-Vega ◽

Yanink Caro-Vega ◽

José Guadalupe Rendón-Maldonado ◽

...

Keyword(s):

Human Papillomavirus ◽

Oral Cavity ◽

Anal Canal ◽

Cross Sectional Study ◽

Cross Sectional ◽

Oral Infections ◽

Immunodeficiency Virus ◽

High Prevalence ◽

Sex With Men ◽

High Risk Hpv

Abstract Background Incidence of anal and oral infections with Human Papillomavirus (HPV) is increasing, particularly among Human Immunodeficiency Virus-positive (HIV+) men. HPV type 16 has exhibited the highest incidence and only limited data is available on other prevalent types, variants of HPV16, as well as associated factors. We were interested in identifying prevalent HPV types, variants of type 16, as well as factors associated with HPV16 infections in the oral cavity of HIV+ men who have sex with men (MSM). Methods A cross-sectional study of oral cavity samples from HIV+ MSM, that in a previous study were identified as positive for HPV16 in the anal canal. Cells from the oral cavity (102 samples, paired with 102 from the anal canal of same patient) were used to extract DNA and detect HPV infections using INNO-LiPA HPV Genotyping Extra II, and PCR. From these, 80 samples (paired, 40 anal and 40 oral) were used to identify variants of type 16 by sequencing. Statistical differences were estimated by the X2 test, and p values equal to or less than 0.05 were considered significant. SPSS ver. Twenty-four statistical software (IBM Corp) was used. Results We found a high prevalence of High-Risk HPV (HR-HPV) and Low-Risk HPV (LR-HPV). Patients were positive in the oral cavity for HR types; 16, 39 and 18 (80.4, 61.8 and 52.9% respectively) and LR types 11 and 6 (53.9 and 34.3% respectively). Surprisingly, only European variants of type 16 were found in the oral cavity, although American Asian (22.5%) and African (2.5%) variants were identified in the anal canal. The analysis showed that CD4 counts could be the most important risk factor associated with HR-HPV infections in the oral cavity, anal canal or both anatomical regions. The risk of infection of the oral cavity with type 18 increased in men diagnosed with HIV for more than 6 years. Conclusions Prevalence of both HR and LR HPV’s in the oral cavity of Mexican HIV+ MSM is very high. The fact that only European variants of HPV16 were found in the oral cavity suggest a possible tropism not previously described.

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Argyrophilic nucleolar organizer regions in oral mucosa cells of crack and cocaine users: a cross-sectional study

Environmental Science and Pollution Research ◽

10.1007/s11356-020-09892-w ◽

2020 ◽

Vol 27 (30) ◽

pp. 37920-37926

Author(s):

Rosângela Góes Rabelo ◽

Arthur Pias Salgueiro ◽

Fernanda Visioli ◽

Viviane Palmeira da Silva ◽

Maria das Graças Alonso Oliveira ◽

...

Keyword(s):

Oral Mucosa ◽

Nucleolar Organizer ◽

Cross Sectional Study ◽

Nucleolar Organizer Regions ◽

Sectional Study ◽

Cross Sectional ◽

Cocaine Users ◽

Argyrophilic Nucleolar Organizer Regions

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Possible association between craniofacial dimensions and genetic markers in ESR1 and ESR2

Journal of Orthodontics ◽

10.1177/1465312520901725 ◽

2020 ◽

Vol 47 (1) ◽

pp. 65-71 ◽

Cited By ~ 1

Author(s):

Marjorie Ayumi Omori ◽

Jennifer Tsi Gerber ◽

Guido Artemio Marañón-Vásquez ◽

Mirian Aiko Nakane Matsumoto ◽

Suyany Gabriely Weiss ◽

...

Keyword(s):

Genetic Markers ◽

Cross Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Lateral Cephalograms ◽

Mandibular Body ◽

Chi Square Test ◽

Hardy Weinberg Equilibrium ◽

Polymerase Chain ◽

School Of Dentistry

Objective: To investigate the association of genetic markers in ESR1 and ESR2 with craniofacial measurements. Design: Cross-sectional study. Setting: School of Dentistry of Ribeirão Preto, University of São Paulo. Participants: A total of 146 biologically unrelated, self-reported Caucasian Brazilians with no syndromic conditions were included. Methods: Sagittal and vertical measurements (ANB, S-N, Ptm’-A’, Co-Gn, Go-Pg, N-Me, ANS-Me, S-Go and Co-Go) from lateral cephalograms were examined for craniofacial evaluation. DNA was extracted from saliva and genetic markers in ESR1 (rs2234693 and rs9340799) and in ESR2 (rs1256049 and rs4986938) were analysed by real-time polymerase chain reaction. Hardy–Weinberg equilibrium was evaluated using the Chi-square test within each marker. The associations between craniofacial dimensions and genotypes were analysed by linear regression and adjusted by sex and age. The established alpha was 5%. Results: Individuals carrying CC in ESR1 rs2234693 had a decrease of –3.146 mm in ANS-Me ( P = 0.044). In addition, rs4986938 in ESR2 was associated with S-N measurement ( P = 0.009/ ß = –3.465). This marker was also associated with Go-Pg measurement, in which the CC genotype had a decrease of –3.925 mm in the length of the mandibular body ( P = 0.043). Conclusion: The present study suggests that in ESR1 and ESR2 are markers for variations in the craniofacial dimensions. However, further research should confirm the results.

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Effects of Diabetes and Hypertension on Oral Mucosa and TGFβ1 Salivary Levels

Brazilian Dental Journal ◽

10.1590/0103-644020181868 ◽

2018 ◽

Vol 29 (3) ◽

pp. 309-315

Author(s):

Lisiane Bernardi ◽

Bárbara Capitanio de Souza ◽

Nicole Canalli Sonda ◽

Fernanda Visioli ◽

Pantelis Varvaki Rados ◽

...

Keyword(s):

Oral Mucosa ◽

Salivary Flow ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Post Test ◽

Healthy Control ◽

History Of ◽

Spearman Test ◽

Test Correlation

Abstract The aim of this study was to investigate salivary levels of TGFβ1 and proliferation/ maturation of epithelial mucosa cells in diabetic and hypertensive patients. Design: in this cross-sectional study, whole stimulated saliva and oral mucosa exfoliative cytology specimens were collected from 39 patients that were healthy (control, n=10) or presented history of arterial hypertension (HAS, n=9), diabetes mellitus (DM, n=10) or both (DM+HAS, n=10). Salivary flow rate (SFR), TGFβ1 level in saliva, AgNORs and the epithelial maturation were evaluated. Non-parametric Kruskal-Wallis test, followed by Dunn’s multiple comparison post-test and the Spearman test correlation analysis were used. SFR showed a significant decreased in DM and DM+HAS (0.47±0.11 and 0.64±0.43 mL/min) when compared to control (1.4±0.38 mL/min). DM+HAS presented the highest value of TGFβ1 concentration (24.72±5.89 pg/mL). It was observed a positive correlation between TGFβ1 and glycaemia (R=0.6371; p<0.001) and a negative correlation between TGFβ1 and saliva (R=-0.6162; p<0.001) and glycaemia and SFR (R=-0.5654; P=0.001). AgNORs number and status of maturation of mucosa cells were similar for all conditions. DM and DM+HAS presented the lowest SFR, which correlated with increased TGFβ1 levels. Despite the higher TGFβ1 secretion it was not observed changes in the morphology or proliferation of epithelial cells when diabetes or hypertension was present.

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