scholarly journals Formulation and Evaluation of Antimicrobial Herbal Soap

2021 ◽  
Vol 71 (2) ◽  
Author(s):  
Seetha Devi Dr.A. ◽  
Sivani D.V. ◽  
Anusha D. ◽  
Sarath G. ◽  
Syed Meraj Sultana
Keyword(s):  
Antibacterial Activity ◽  
Cost Effective ◽  
Diffusion Method ◽  
Skin Infections ◽  
Ocimum Tenuiflorum ◽  
Bacterial Skin Infections ◽  
Herbal Plant ◽  
Significant Attention ◽  
Bacterial Effect ◽  
Agar Well Diffusion Method

Bacterial skin infections are most common amongst people, requiring significant attention for treatment and also for maintaining healthy skin. Some herbal plant extracts and their oils were found to have antibacterial activity. The aim and objective of the present study are to formulate and evaluate anti-bacterial herbal soap using Azadirachta indica, Ocimum tenuiflorum oils. The antibacterial activity of the prepared formulations was tested using the agar well diffusion method against the organisms Pseudomonas aeruginosa, Staphylococcus aureus and, Escherichia coli and they exhibited a good anti-bacterial effect. The prepared formulations were evaluated for various physicochemical parameters for which good characteristics were observed. The easy availability of plants and their effectiveness helps manufacturers with cost-effective benefits and with less or no side effects.

scholarly journals Development and Evaluation of Antibacterial Polyherbal Bath Soap

2021 ◽  
Vol 6 (5) ◽  
pp. 45-52
Author(s):  
Seema U. Shinde ◽  
Nikita D. Gidde ◽  
Jamir. A. Tamboli
Keyword(s):  
Antibacterial Activity ◽  
Curcuma Longa ◽  
Antibacterial Properties ◽  
Cost Effective ◽  
Skin Infections ◽  
E Coli ◽  
Diffusion Technique ◽  
Ongoing Care ◽  
Bacterial Skin Infections ◽  
Herbal Plant

Bacterial skin infections are the most prevalent among individuals, necessitating immediate treatment as well as ongoing care to preserve healthy skin. Because some herbal plant extracts have antibacterial properties, the goal of this research is to make an antibacterial poly herbal bath soap using curcuma longa[Turmeric] and Organum Vulgare [Oregano The antibacterial activity of prepared soap was evaluated against staphylococcus aureus, E. coli, and Aspergillus Niger using the agar well diffusion technique. The developed Polyherbal formulation had a good antibacterial activity, and it was analysed for several physicochemical parameters and whether it has good characteristics. Plants are easily obtainable, and their efficacy helps manufacturers in achieving cost-effective outcomes with few or no side effects.

scholarly journals Antibacterial, antioxidant, and sun protection potential of selected ethno medicinal plants used for skin infections in Uganda

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Jane Namukobe ◽  
Peter Sekandi ◽  
Robert Byamukama ◽  
Moses Murungi ◽  
Jennifer Nambooze ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Medicinal Plants ◽  
Inhibitory Concentration ◽  
Antioxidant Properties ◽  
Sun Protection ◽  
Albino Rats ◽  
Skin Infections ◽  
Double Beam ◽  
Protection Potential ◽  
Bacterial Skin Infections

Abstract Background Rural populations in Uganda rely heavily on medicinal plants for the treatment of bacterial skin infections. However, the efficacy of these medicinal plants for their pharmacological action is not known. The study aimed at evaluating the antibacterial, antioxidant, and sun protection potential of Spermacoce princeae, Psorospermum febrifugum, Plectranthus caespitosus, and Erlangea tomentosa extracts. Methods The plant samples were extracted by maceration sequentially using hexane, dichloromethane, ethyl acetate, methanol, and distilled water. Antibacterial activity of each extract was carried out using an agar well diffusion assay against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonie, Streptococcus pyogenes, and Salmonella typhi. Acute dermal toxicity of the aqueous extract of S. princeae and P. febrifugum, and E. tomentosa was assessed in young adult healthy Wistar albino rats at a dose of 8000 and 10,000 mg/kg body weight. The antioxidant activity of each extract was carried out using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay. The sun protection factor was determined using Shimadzu UltraViolet-Visible double beam spectrophotometer between 290 and 320 nm. Results The plant extracts showed good antibacterial activity against the tested bacterial strains with minimum inhibitory concentration (MIC) ranging between 3.12 and 12.5 mg/ml. There was no significant change in the levels of creatinine, alanine aminotransferase, and aspartate aminotransferase in the rats even at a higher dose of 10,000 mg/kg, which was related to the results of biochemical analysis of the blood samples from the treated and control groups. The aqueous and methanol extracts of S. princeae showed potential antioxidant properties, with half maximal inhibitory concentration (IC50) values of 59.82 and 61.20 μg/ml respectively. The organic and aqueous extracts of P. caespitosus showed high levels of protection against Ultraviolet light with sun protection potential values ranging between 30.67 and 37.84. Conclusions The study demonstrated that the selected medicinal plants possessed good antibacterial, antioxidant, and sun protection properties. Therefore, the plants are alternative sources of antibacterial, antioxidant, and sun protection agents in managing bacterial skin infections.

scholarly journals Antibacterial Activity of Silver Nanoparticles Synthesized by Bark Extract of Syzygium cumini

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ram Prasad ◽  
Vyshnava Satyanarayana Swamy
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Cost Effective ◽  
Diffusion Method ◽  
Bark Extract ◽  
Force Microscopy ◽  
Atomic Force ◽  
Cost Effective Method ◽  
Uv Visible ◽  
Major Attention

The unique property of the silver nanoparticles having the antimicrobial activity drags the major attention towards the present nanotechnology. The environmentally nontoxic, ecofriendly, and cost-effective method that has been developed for the synthesis of silver nanoparticles using plant extracts creates the major research interest in the field of nanobiotechnology. The synthesized silver nanoparticles have been characterized by the UV-visible spectroscopy, atomic force microscopy (AFM), and scanning electron microscopy (SEM). Further, the antibacterial activity of silver nanoparticles was evaluated by well diffusion method, and it was found that the biogenic silver nanoparticles have antibacterial activity against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 29213), Pseudomonas aeruginosa (ATCC 27853), Azotobacter chroococcum WR 9, and Bacillus licheniformis (MTCC 9555).

scholarly journals Green Synthesis of Silver Nanoparticles from the Extracts of Fruit Peel of Citrus tangerina, Citrus sinensis, and Citrus limon for Antibacterial Activities

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Moira Carmalita Dharsika Niluxsshun ◽  
Koneswaran Masilamani ◽  
Umaramani Mathiventhan
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Citrus Sinensis ◽  
Orange Peel ◽  
Cost Effective ◽  
Diffusion Method ◽  
Citrus Limon ◽  
Fruit Peel ◽  
Visible Absorption ◽  
Uv Visible

Wide application of nanoparticles motivates the need for synthesising them. Here, a nontoxic, eco-friendly, and cost-effective method has been established for the synthesis of silver nanoparticles using extracts of lemon peel (Citrus limon), green orange peel (Citrus sinensis), and orange peel (Citrus tangerina). The synthesised nanoparticles have been characterised using UV-visible absorptionspectroscopy, Fourier transform infrared spectroscopy, and transmission electron microscopy (TEM). The UV-visible absorption spectrum of these synthesised silver nanoparticles shows an absorption peak at around 440 nm. TEM images show different shaped particles with various sizes. Furthermore, the antibacterial activity of silver nanoparticles was appraised by a well-diffusion method and it was observed that the green synthesised silver nanoparticles have an effective antibacterial activity against Escherichia coli and Staphylococcus aureus. The outcome of this study could be beneficial for nanotechnology-based biomedical applications.

scholarly journals Giloy (Tinospora Cordifolia): In Vitro Evaluation of Antibacterial Properties

2021 ◽  
Vol 07 (06) ◽  
Author(s):  
Tulsa Devi ◽  
Keyword(s):  
Antibacterial Activity ◽  
Methanolic Extract ◽  
Water Extract ◽  
Hot Water ◽  
Tinospora Cordifolia ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Hot Water Extract ◽  
Agar Well Diffusion Method

Antibiotic resistance has become a global concern and hence, the search for other source of antimicrobials initiated to find a way to control infections in future. The main objective of this paper is to screen Giloy (Tinospora cordifolia) for its antibacterial activity. The stem of Tinospora cordifolia is used to prepare extract for determining it’s in vitro antibacterial activity as per the agar well diffusion method. In the agar well diffusion method 100μl of 24 hr broth culture of bacteria was aseptically and evenly swabbed on Mueller Hinton agar plates. Wells of about 8 mm diameter were aseptically cut using sterile cork-borer. 100 μl of plant extracts of different concentrations were then placed into the separate wells. The plates were incubated at 37 oC for 24hr. Antimicrobial activity of the giloy was determined by measuring the diameter of zone of inhibition. The methanolic extract of Tinospora cordifolia showed 13, 11, 9 and 5 mm zone of inhibition in S. aureus cultures by using 100, 75, 50 and 25 mg/ml concentration, respectively while hot water extract of Tinospora cordifolia showed 14, 12, 10 and 8 mm zone of inhibition for S. aureus by using 100, 75, 50 and 25 mg/ml concentration, respectively and the cold extract of Tinospora cordifolia showed 10, 8, 5 and 0 mm zone of inhibition for S. aureus by using 100, 75, 50 and 25mg/ml concentration, respectively. The methanolic extract of Tinospora cordifolia indicated 12, 10, 6 and 4 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25 mg/ml concentration, respectively and the hot water extract of Tinospora cordifolia showed 16, 14, 12 and 10 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25mg/ml concentration, respectively. The cold water extract of Tinospora cordifolia showed 13, 10, 8, and 5 mm zone of inhibition in cultures of E.coli by using 100, 75, 50 and 25 mg/ml concentration, respectively. It has been observed that Tinospora cordifolia showed very promising results as indicated by the zone of inhibition of bacterial culture through agar well diffusion method that varies from few mm to few cm. This study indicates the in-vitro antibacterial effect of Giloy which needs further validation through in-vivo studies.

scholarly journals Antibacterial activity of graphene oxide nanosheet against multidrug resistant superbugs isolated from infected patients

2020 ◽  
Vol 7 (7) ◽  
pp. 200640 ◽  
Author(s):  
Md. Toasin Hossain Aunkor ◽  
Topu Raihan ◽  
Shamsul H. Prodhan ◽  
H. S. C. Metselaar ◽  
Syeda Umme Fahmida Malik ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Graphene Oxide ◽  
Antimicrobial Property ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Drug Resistant ◽  
Graphene Nanosheet ◽  
Solid Agar ◽  
Good Biocompatibility ◽  
Agar Well Diffusion Method

Graphene oxide (GO) is a derivative of graphene nanosheet which is the most promising material of the decade in biomedical research. In particular, it has been known as an antimicrobial nanomaterial with good biocompatibility. In this study, we have synthesized and characterize GO and checked its antimicrobial property against different Gram-negative and Gram-positive multidrug drug resistant (MDR) hospital superbugs grown in solid agar-based nutrient plates with and without human serum through the utilization of agar well diffusion method, live/dead fluorescent staining and genotoxicity analysis. No significant changes in antibacterial activity were found in these two different conditions. We also compare the bactericidal capability of GO with some commonly administered antibiotics and in all cases the degree of inhibition is found to be higher. The data presented here are novel and show that GO is an effective bactericidal agent against different superbugs and can be used as a future antibacterial agent.

Antibacterial Activity of Alimentary Plants Against Staphylococcus aureus Growth

1994 ◽  
Vol 22 (02) ◽  
pp. 169-174 ◽  
Author(s):  
Cristina Pérez ◽  
Claudia Anesini
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Theobroma Cacao ◽  
Plant Material ◽  
Penicillin G ◽  
Diffusion Method ◽  
Piper Nigrum ◽  
Ripe Fruit ◽  
Ethanol Extracts ◽  
Agar Well Diffusion Method

Alimentary plants were screened for antibacterial activity against a penicillin G resistant strain of Staphylococcus aureus. Twenty-five samples of plant material corresponding to 21 species from 13 families were used. Both aqueous and ethanol extracts were obtained from them. Antibacterial activity was determined by the agar-well diffusion method, using cephazolin as a standard antibiotic. Seventeen ethanol extracts were found active. Eugenia caryophyllata (clavo de olor*) flowers, Myristica fragans (nuez moscada*) seeds, Theobroma cacao (cacao*) seed bark, Triticum sp (trigo*) fruit, Zea mays (maíz*) fruit and Piper nigrum (pimienta*) ripe fruit produced some of the more active extracts (*= Argentine vulgar names).

Synthesis and Antibacterial Activities of N-Phenylpyrazolines from Veratraldehyde

2017 ◽  
Vol 901 ◽  
pp. 124-132
Author(s):  
Artania Adnin Tri Suma ◽  
Tutik Dwi Wahyuningsih ◽  
Deni Pranowo
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacillus Subtilis ◽  
Bacillus Cereus ◽  
Shigella Flexneri ◽  
Inhibition Zone ◽  
Antibacterial Activities ◽  
Diffusion Method ◽  
Agar Well Diffusion Method

Some novel N-phenylpyrazolines were synthesized and investigated for their antibacterial activitiy. Chalcones 2-4 which were prepared from acetophenone and veratraldehyde derivatives were reacted with phenylhydrazine to give N-phenylpyrazolines 5-7. All of the synthesized compounds were characterized using FTIR, GC-MS, and NMR spectrometers. Further, antibacterial activity of N-phenylpyrazolines were evaluated by agar well-diffusion method against Staphylococcus aureus, Bacillus cereus, Bacillus subtilis, Escherichia coli, and Shigella flexneri. The highest activity (highest inhibition zone) of compound 5 was 2.6 mm (at 1000 ppm) against B. subtillis, compound 6 was 7.25 mm (at 1000 ppm) against S. aureus, and compound 7 was 6.75 mm (at 500 ppm) against S. aureus. The results indicated that compound 6 and 7 exhibited promising antibacterial activity.

scholarly journals Antioxidant, anti-bacterial activity of Perilla frutescens ethanol extract and induction of hairy roots by Agrobacterium rhizogenes

2020 ◽  
Vol 5 (1) ◽  
pp. first
Author(s):  
TRA DONG PHUONG ◽  
LE THI MONG VUONG ◽  
QUACH NGO DIEM PHUONG
Keyword(s):  
Antibacterial Activity ◽  
Agrobacterium Rhizogenes ◽  
Hairy Roots ◽  
Ethanol Extract ◽  
Secondary Compounds ◽  
Perilla Frutescens ◽  
Diffusion Method ◽  
Dpph Method ◽  
Specific Reactions ◽  
Agar Well Diffusion Method

Perilla frutescens, a plant of the Lamiaceae, is commonly used for traditional medicine to treat diseases (cold, headache, cough, tympanites, poisoning, ...) because it contains many secondary compounds with bioactivities. Roots, stems and leaves of P. frutescens have been extracted with ethanol. These extracts have also been investigated antioxidant by DPPH method and antibacterial by agar-well-diffusion method. The results showed that these extracts possess antioxidant and antibacterial activity. By specific reactions, we found that phenols, flavonoids, saponins, alkaloids and glycosides were contained in all extracts of P. frutescens, but triterpenoids were only found in leaf extract. These secondary compounds are involved in the antioxidant and antibacterial activity of P. frutescens. Next, hairy roots of P. frutescens were induced by Agrobacterium rhizogenes ATCC 15834. The results suggested that leaves were the highest-efficiency (67.67 ± 3.51 % of samples produced hairy roots). 20 minutes of immersion and 72 hours of co-culture are optimal for induction of hairy roots. These results are a pre-requisition for further studies related to hairy root cultures aimed production of bioactive compounds.

scholarly journals Antifungal Activity of Various Extracts of Seeds of the Plant Malva Parviflora (Linn)

2017 ◽  
Vol 14 (4) ◽  
pp. 1409-1412
Author(s):  
Jadhav Raina ◽  
Parihar Sangeeta
Keyword(s):  
Antibacterial Activity ◽  
Antifungal Activity ◽  
Antifungal Agent ◽  
Antifungal Agents ◽  
Diffusion Method ◽  
Dilution Method ◽  
Significant Activity ◽  
Water As Solvent ◽  
Malva Parviflora ◽  
Agar Well Diffusion Method

ABSTRACT: Development of more effective and less toxic antifungal agents is required for the treatment of various fungal disease.Plants and their extraction preparation have beenused as medicine against infectious diseases.The present study was aimed to study, the antifungal activity of the seeds of various seed abstract of plant Malva Parviflora (Linn). The antifungal activity of seeds extract of plant was determine by using agar well diffusion method,MIC(minimum inhibitoryconcentration) and MFC (minimum fungicidal count)by using micro dilution method . The seeds extract of the plant were examined using Methanol, Ethyl acetate ,Petroleum ether and water as solvent and tested against different fungi pathogens. From the result it can be concluded that the all the seeds extract shows the significant activity against the micro organism, hence these extract may be used as a source of antifungal agent obtained from herbal medicine and may be explore as new and effective antifungal agent. Various solvent extracts of the plant Malva parvifiora (Linn) have been found to possess enough antibacterial activity and may potentially be explored as human antifungal agent.

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