scholarly journals Study on Dengue fever in children: A Tertiary care hospital during dengue out-break

2019 ◽  
Vol 1 (Number 1) ◽  
pp. 6-9
Author(s):  
Tamanna Begum ◽  
Sadika Kadir ◽  
Khayerul Islam ◽  
Rafiqul Islam ◽  
Romela Yeasmin ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Tertiary Care ◽  
Warning Sign ◽  
Care Hospital ◽  
Male Predominance ◽  
Dengue Outbreak ◽  
Test Kit ◽  
Wide Range ◽  
The Common ◽  
Body Ache

This is a prospective observational study conducted in the department of Paediatrics from June to August 2019 during the time of dengue outbreak. All children age up to 14 years with either positive NSI antigen or serological Gg, IgM test Kit or ELISA methods were taken into the study. Total 39 cases were enrolled in this study. Mean age was 7.2 ± 2 years, majority were in the age group of 5-10 years (51%) followed by <5 years (38%),> 10 years (35%) respectively. Male predominance was observed in this study (69.20%). Most of the patient admitted in August (73%), then July (33%) and June (15%) during dengue outbreak. The common symptoms were fever100%, rashes (6.8%), body ache (25% and warning sign like vomiting (45%) and others. Among the enrolled cases dengue fever was (75%) than DHF (7.5%), DSS (2.5%) respectively. About 75% were NSI positive and 2.5% were 1gM ±IgG. Thrombocytopenia present in100% cases, among them 38% with plate <15000.Lowest limit was >20-30 thousands (5%) cases. All patient was treated with IVF, platelet was transfused in 20%, FFP was given (20%). Dengue has wide range of symptoms mild to severe. Complication is rare platelet transfusion is not randomly required despite of thrombocytopenia. Supportive treatment and patient monitor are very important in management of Dengue.

scholarly journals Dengue Fever : Study of 100 Cases in a Tertiary Care Hospital in Dhaka City

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 3-7
Author(s):  
A H M Karnal ◽  
K H Mollah ◽  
A Begum ◽  
K Khoda ◽  
S Tanzeem ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Tertiary Care ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Care Hospital ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Body Ache

Dengue is a rapidly spreading mosquito-borne viral disease worldwide. The endemicity in Bangladesh is also increasing gradually. The study was a prospective observational one, documented the presenting features and outcome of management. It was carried out in Department of Medicine in Holy Family Red Crescent Medical College Hospital, Dhaka from June 2013 to December 2013. Total 100 admitted cases of both sera positive and sera-negative were included in this study. Detailed history was taken, clinical examination and relevant investigations were done. Out of 100 patients 54 (54%) were male and 46 (46%) were female. So male to female ratio was 1.7:1. The age of the patients ranged from 12-75 years. Among them 20-40 years age group was highest 63%. Patients of higher socio-economic group were (69%) more affected. Out of 100 cases 54 had classical dengue fever (DF), 46 had dengue hemorrhagic fever (DHF). Antibody was positive in 81% cases. All patients presented with high fever, headache in 90%, retro-orbital pain in 45%, body ache in 56%, and backache in 48%. Leucopenia found in 60, platelet count <100x1091L was in 57, HCT- normal 17, <20% rise in 48%, ?20% rise in 28%. With proper management all patients were recovered.

scholarly journals Clinico- Serological Profile and Geographical Distribution of Dengue Fever from a Tertiary Care Hospital, South India

2021 ◽  
Author(s):  
Morubagal Raghavendra Rao ◽  
Rashmi Padmanabha Mahale ◽  
Sowmya Shivappa ◽  
Vidyavathi B. Chitharagi ◽  
Ranjitha S. Gowda ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Geographical Distribution ◽  
Urban Areas ◽  
Tertiary Care ◽  
Control Measures ◽  
Care Hospital ◽  
Ns1 Antigen ◽  
Different Seasons ◽  
The Common ◽  
Geographical Maps

Dengue fever is one of the common viral illnesses linked with significant morbidity and mortality. Of late, there is rapid increase in dengue cases in India. The present study aimed to known dengue seropositivity in different seasons of a year, other laboratory parameters and its geographical distribution. During the study period of 15 months 4172 patients hospitalized with probable dengue fever were included. Dengue serology was done for all cases by ELISA(J. Mitra & Co). Demographic details were taken to create geographical maps of the disease. Of the 4172 suspected dengue cases, 817 had confirmed dengue illness. Of these 817 cases, 584 showed Ns1 antigen (71.4%), 150 IgM antibody (18.3%), and 38 had both Ns1 and Ig M (4.6%). Platelet count less than 1,00,000 were seen in 566 (69.27%) patients. Dengue was noticeably more during monsoon time (June to September) of a year. Through geographical maps major clusters were noticed urban areas of Mysuru and Krishnaraja Nagara , while few clusters were also observed in Periyapatna and T Narsipura taluks of Mysuru district. To minimize the load of dengue cases and its death rate better community awareness and vector control measures need to be strengthened during monsoon especially in areas where burden of the disease is more. This study helps in early preparedness of the authorities concerned in controlling possible epidemics in future.

scholarly journals EXPERIENCE OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS-2 (SARS-COV-2) - COVID-19 AT A TERTIARY CARE HOSPITAL IN QUETTA, BALUCHISTAN

2021 ◽  
Vol 71 (6) ◽  
pp. 2152-56
Author(s):  
Naveed Asif ◽  
Shahzeb Ahmed Satti ◽  
Alveena Younas ◽  
Mehwish Gilani ◽  
Waqas Shaikh ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Signs And Symptoms ◽  
Military Hospital ◽  
Nasopharyngeal Swab ◽  
Care Hospital ◽  
Male Predominance ◽  
Wide Range ◽  
Study Participants

Objective: To share the experience of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-COVID-19 at a tertiary care hospital in Quetta, Baluchistan. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pathology, Combined Military Hospital Quetta, from Mar to Dec 2020. Methodology: This study included 14,741 study participants presenting to CMH Quetta with signs and symptoms of Coronavirus Disease-19 (COVID-19) and others undergoing COVID-19 PCR for screening purpose. Nasopharyngeal swab collected from these study participants were tested for COVID-19 viral RNA by real-time Reverse Transcription Polymerase Chain reaction (RT-PCR) assay. Results: Out of these 14,741 study participants, 1886 (12.7%) were found to be SARS-CoV-2 PCR positive. Among 1886 study participants, 1503 (80%) were males while 383 (20%) were females. Mean age of the study participants was 36 ± 14 years. Most frequent clinical presentations were body aches (96.5%), fever (94.1%), cough (66.8%) and loss of appetite (68.2%). Around 67 (3.5%) positive study participants were asymptomatic. Conclusion: In this study, we observed male predominance but severity of signs and symptoms among female study participants. SARS-COVID-19 caused disease with wide range of clinical spectrum and disease can be fatal as well.

scholarly journals Clinical and laboratory profile of dengue fever in hospitalized children among South Indian population

2018 ◽  
Vol 5 (6) ◽  
pp. 2258
Author(s):  
Raghava Badabagni ◽  
Rajesh Kumar Sethi
Keyword(s):  
Pleural Effusion ◽  
Dengue Fever ◽  
Tertiary Care ◽  
Common Symptom ◽  
South Indian Population ◽  
Care Hospital ◽  
Male Predominance ◽  
South Indian ◽  
Ns1 Antigen ◽  
Laboratory Profile

Background: Dengue fever is currently regarded globally as one of the most important mosquito-borne viral diseases. Children suffering from dengue fever shows a large variation in clinical features and laboratory parameters.   This study was focused to evaluate the clinical presentation, associated laboratory and radiological profiles that may be useful to diagnose dengue fever.Methods: Prospective observational study including 500 children with serological positive dengue fever admitted in a tertiary care hospital in South India.Results: In this study mean age of presentation of children with dengue fever was 8.4±1.2 years with male predominance. The incidence of children presenting with DF, DHF and DSS was 61%, 23% and 16% respectively. The most common symptom was fever in 100% patients followed by vomiting in 69%, abdominal pain in 64.2%, bleeding manifestations in 43% and periorbital pain in 28.8% of patients. The NS1 was positive in 39.2% cases, dengue IgM in 29% of cases and IgG positive in 30.4% cases. By ultrasonography it was observed that 34% of patients had ascites, 28% with pericholecystic edema, 12% with bilateral pleural effusion, 10% with right sided Pleural effusion and hepatomegaly and 5% with splenomegaly. The most common cause of death was cardiorespiratory arrest secondary to DIC.Conclusions: Detection of Ns1 antigen to diagnose dengue is proposed to be superior when compared to antibodies detection. It is also concluded that diagnosis of dengue should be made comprehensively by clinical examination with supporting laboratory and radiological investigations.

scholarly journals A study to determine the severity based outcome of pediatric patients with dengue spectrum disorders in a tertiary care hospital

2019 ◽  
Vol 7 (1) ◽  
pp. 154
Author(s):  
Vijaysuryakiran K. M. ◽  
Mounesh Pattar ◽  
Sanjay Paida
Keyword(s):  
Dengue Fever ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Warning Signs ◽  
Severe Dengue ◽  
Warning Sign ◽  
High Morbidity ◽  
Care Hospital ◽  
Increased Risk ◽  
Spectrum Disorders

Background: Dengue Fever (DF) has become a major global public health problem. The majority of dengue viral infections are self-limiting, but complications may cause high morbidity and mortality. Dengue infection ranges from mild illness to a severe form of haemorrhagic fever and shock syndrome which may prove fatal. Objective of the study was to determine severity-based outcome in children with dengue spectrum disorder in a tertiary care centre in Mumbai.Methods: It was a prospective, non-interventional, observational, surveillance study conducted over 14 months (from September 2016 till October 2017). Children aged <18 years admitted to Nanavati Super Specialty Hospital, Mumbai diagnosed with dengue spectrum disorders according to WHO 2009 classification with clinical features and laboratory investigation confirming dengue were enrolled as study participants.Results: Out of 127 patients, 57(44.9%) were females and 70(55.1%) were males. 81(63.8%) were ward patients, 46(36.2%) required PICU admission. 17(13.4%) patients had dengue with warning signs, 100(78.7%) had dengue without warning signs and 10(7.9%) had severe dengue according to WHO 2009 case classification of dengue. 122(96.1%) were discharged home, 4(3.1%) died of dengue and dengue related complications all four deaths occurred in children with severe dengue.Conclusions: This study showed that commonest inpatient admission category among children with dengue according to WHO 2009 classification was dengue without warning signs Overall mortality in patients with dengue fever without warning sign as well those with warning sign remains very low. Children presenting with severe dengue associated with either organ failure or refractory shock are at increased risk of mortality.

scholarly journals Clinicopathological Profile and Outcome of Dengue Fever: A Tertiary Care Hospital Experience

2021 ◽  
Vol 39 (4) ◽  
pp. 213-219
Author(s):  
Md Anisur Rahman ◽  
Most Umme Habiba Begum ◽  
Hafez Md Nizam Uddin ◽  
Serazum Monira ◽  
Md Bodrul Millat
Keyword(s):  
Dengue Fever ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Acalculous Cholecystitis ◽  
Military Hospital ◽  
Care Hospital ◽  
Male Predominance ◽  
Study Results ◽  
Clinicopathological Profile ◽  
Age Range

Introduction: Diverse manifestation of recent dengue outbreak has posed a challenge to pre-existing nature of dengue virus infection and management. This study was designed to observe clinicopathological profile and analyze the diverse presentation and outcome of dengue syndrome in recent outbreak in Bangladesh. Methods: This was a hospital based observational study, carried out in Medicine department of Combined Military Hospital (CMH) Dhaka cantonment in between May and September 2019. Total 300 laboratory-confirmed dengue cases aged more than 11 years presenting within 7 days of symptom onset were studied. Patients who presented 7 days after the onset of symptoms or those who were transferred to other hospitals were excluded from study. Results: Total patients were 300 with male predominance (187, 62.3%) and mean age±SD was 37.6±7.5years with age range 12 to76 years; common presentations were fever (300, 100%),headache (265, 88.3%), skin rash (197, 65.7%), bodyache (186, 62.0%),vomiting (152, 50.7%), diarrhoea (65, 21.7%),abdominal pain (58, 19.3%), and bleeding manifestation (36, 12.0). Eighty four (28%) patient had classical dengue fever (DF), 61 (20.3%) had dengue haemorrhagic fever (DHF), 45(15%) had dengue shock syndrome (DSS) and 110(36.7%) had expanded dengue syndrome(EDS). Relevant investigations showed 157(52.3%) patients had leukopenia,18(6%) had leukocytosis, 254(84.7%) had thrombocytopenia with lowest platelet count 1x109/L,135(45%) had abnormal ALT, 110(36.7%) had abnormal AST, 84(28%) had hyponatraemia,43(14.3%) had AKI,125(41.7%) had pleural effusion with 36(12%) bilateral;102(34%) had ascites, 25(8.3%) developed acalculous cholecystitis;7(2.3%) patient developed cerebrovascular accident. Eighteen (6%) patients required mechanical ventilation and 15 (5%) patients required haemodialysis. Regarding outcome, 5 (1.7%) patients died and 295 (98.3%) patients survived. Conclusion: Dengue fever was presented with common as well as other features and involved a number of organs including liver, kidneys, brain, pleura, peritoneum, and gall bladder and had diverse manifestations and adverse outcome. J Bangladesh Coll Phys Surg 2021; 39: 213-219

scholarly journals Clinical-epidemiological profile of dengue fever in children admitted in a tertiary care hospital in Kolkata, West Bengal, India

2018 ◽  
Vol 5 (5) ◽  
pp. 1914 ◽  
Author(s):  
Suchi Acharya ◽  
Nupur Ganguly ◽  
Sumon Poddar ◽  
Apurba Ghosh
Keyword(s):  
Dengue Fever ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Severe Dengue ◽  
Warning Sign ◽  
Care Hospital ◽  
Atypical Manifestations ◽  
Epidemiological Profile ◽  
Clinical Records

Background: Dengue infection has been known to be endemic in India for centuries. In recent years, the disease has changed its course manifesting in its severe form as Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS), with increasing frequency of outbreaks. The objective of the present study was to study the clinical and epidemiological profile of dengue fever in children admitted in a tertiary care hospital.Methods: Clinical records of children aged 0-15 years with serologically confirmed dengue infection admitted at the Institute of Child Health, Kolkata during the Dengue outbreak (June 2016 to November 2016) were reviewed.Results: Out of 958 cases of Dengue fever majority were boys 565 (59%), with M: F ratio of 1.4:1, and among them majority (40%) were in the age group of 5-10 years. Maximum number of cases were seen in the month of September 282 (29.4%).   65.6% cases had dengue fever without warning sign, while 28.6% had dengue fever with warning sign and 5.7% had severe dengue. Among the severe dengue cases 72% were less than 5 years of age while only 28% were more than 5 years of age.  Out of 958 cases we had 63 (6.6%) cases of dengue with atypical manifestations. Seizure was the most common atypical manifestation. Six children expired with a Case Fatality Rate of 0.6%. Dengue shock syndrome was the leading cause of death.Conclusions: Dengue affects all age groups, but children less than 5 years are more prone for developing severe dengue. Atypical manifestations are becoming more common in dengue fever, which can delay the diagnosis so careful observation from the clinician side is required to prevent any serious morbidity or mortality.

scholarly journals A STUDY OF DEMOGRAPHIC AND CLINICAL PROFILE OF DENGUE FEVER PATIENTS IN A TERTIARY CARE HOSPITAL, RAJASTHAN

2021 ◽  
pp. 130-132
Author(s):  
Manoj Kumar Gupta ◽  
Raman Sharma ◽  
Sunil Kumar Mahawar ◽  
Shrikant Sharma ◽  
Arvind Palawat
Keyword(s):  
Dengue Fever ◽  
Urban Area ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Profile ◽  
Fluid Replacement ◽  
Severe Dengue ◽  
Warning Sign ◽  
Care Hospital ◽  
Early Management

BACKGROUND: Dengue fever is caused by dengue virus,belongs to Flaviviridae family, transmitted mostly in urban area by Aedes aegypti and in rural area by Aedes albopictus mosquitoes. Dengue still remains challenge for the treating physician due to non-specific clinical presentation such as fever, headache, rashes, myalgia which often overlaps with other endemic infections. Early identifications of warning signs, diagnosis, appropriate fluid replacement and supportive cares can reduce dengue associated mortality. OBJECTIVE: A study of demographic and clinical profile of dengue fever patients in a tertiary care hospital, Jaipur Rajasthan. MATERIAL AND METHOD: A descriptive, prospective,cross sectional,analytic sturdy conducted on dengue fever patient who were admitted in Medicine wards in the period of august 2019 to December 2019. A detailed history, general and systemic clinical examination with hematological profile and biochemical investigations were done. Signs of plasma leakage were assessed by chest rediograph and abdominal ultrasonography,hematocrit etc.patients wewe classified as dengue fever without warning sign,with warning sign and severe dengue. RESULT:Total 210 patients diagnosed as dengue fever based on detection of dengue non-structural protein 1 (NS1),dengue serology [anti-dengue IgM anti-body] in the blood sample.Most cases were males (72.86%),and fever was most common symptom present in all cases.Most affected cases were in 15-25 years age group (57.14%).Maximum patient were from urban area (71.43%).Thrombocytopenia,leucopenia,increased liver enzymes raised hematocrit and bleeding manifestations were found in 87.62%, 46.62%, 95.71%, 6.67% and 58.8% patients respectively. CONCLUSION: Dengue fever can have different clinical manifestations. No specific anti-viral therapy or vaccination available till now. Early diagnosis and early management are needed to reduce complications and mortality.

Assessing the Severity of Acute Pancreatitis with CT Severity Index and Other Conventional Methods in a Tertiary Care Hospital in Tamil Nadu, India – A Comparative Cross-Sectional Study

2021 ◽  
Vol 8 (41) ◽  
pp. 3541-3546
Author(s):  
Jayaprakash Subramani ◽  
Rajesh Prabhu ◽  
Jagadeesapandian Palpandi
Keyword(s):  
Computed Tomography ◽  
Acute Pancreatitis ◽  
Predictive Value ◽  
Tamil Nadu ◽  
Objective Assessment ◽  
Tertiary Care ◽  
Severity Index ◽  
Apache Ii ◽  
Care Hospital ◽  
Male Predominance

BACKGROUND Acute pancreatitis is not uncommon in surgical practice with variable clinical presentation. Because of its potential notable catastrophic complications, it is mandatory to assess the severity at the earliest. In recent times, the decision making in the management is quite difficult due to its complications and outcome. So, an objective assessment of severity based on clinical and laboratory scoring verses computed tomography (CT) severity is still debate, hence the need for study. The purpose of this study was to compare the efficiency of CT severity index verses APACHE II and Ranson criteria in predicting the severity of acute pancreatitis. METHODS A total number of 36 consecutive cases of acute pancreatitis who were admitted between January 2013 and December 2014 in Apollo Specialty Hospitals – Madurai were included in the study. Written informed consent was obtained from all study participants. RESULTS In our study, out of 36 patients, 30 (83.33 %) were males and 6 (16.66 %) were females. The sex distribution shows a clear male predominance. Most of the patients in the present study belonged to the middle age group. Alcohol was the most common cause accounting for 41.7 % of the cases followed by the billiary pathology. CT severity index was the superior tool for prediction of the prognosis and early complications. CONCLUSIONS When using contrast enhanced computed tomography, it was found that there was a significant correlation between the development of organ failure and severity of pancreatitis. The specificity, sensitivity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of Ranson and acute physiology and chronic health evaluation – II (APACHE II) at 48 hours of admission with acute pancreatitis does not correlate in determining the severity of acute pancreatitis. KEYWORDS Acute Pancreatitis, Severity Markers, CT Severity Index

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF STAPHYLOCOCCOUS AUREUS ISOLATED FROM VARIOUS CLINICAL SPECIMENS OF TERTIARY CARE HOSPITAL IN TIRUPATI.

2021 ◽  
pp. 14-15
Author(s):  
Indira Ananthapadmanab asamy ◽  
V. Pavani Sai Mounika ◽  
K. Vijayakumar ◽  
C.H. Srinivasa Rao
Keyword(s):  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Clinical Specimens ◽  
Antimicrobial Susceptibility Pattern ◽  
Wide Range ◽  
Life Threatening ◽  
Mrsa Infection ◽  
Systemic Infections

INTRODUCTION: Staphylococcus aureus causes a wide range of infections including skin and soft tissue infections to life-threatening systemic infections like sepsis, endocarditis. This study ais to evaluate the antimicrobial susceptibility pattern of S.aurues among various clinical specimens. METHODS: The study included 326 S.aurues, isolated from various clinical specimens which were subjected to antimicrobial susceptibility testing as per CLSI guidelines. RESULTS: Among the 326 isolates, the highest were from pus specimens (47.85%), and was from Orthopaedics department (28.53%). Among the isolates, 219 (67.17%) were Methicilin resistant. All isolates were sensitive to Vancomycin, and all urine isolates were sensitive to Nitrofurantoin. The highest resistance was towards Penicillin (87.42%), Erythromycin (85.28), and Ciprooxacin (83.13%). CONCLUSION: The most effective way to prevent MRSA infection in every hospital is by performing continuous surveillance of antibiotic resistance and by following an effetive antibiotic policy.

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