scholarly journals HOW DOES THE REDUCTION OF GLANDULAR TISSUE EFFECT THE FORCE AND BREAST THICKNESS IN MAMMOGRAPHY?

2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Manca Pišek ◽  
Pia Pšenič Pikelj ◽  
Nejc Mekiš ◽  
Erna Alukić ◽  
Keyword(s):  
Statistical Tests ◽  
Age Groups ◽  
Glandular Tissue ◽  
Compression Force ◽  
Oblique View ◽  
Average Glandular Dose ◽  
Left And Right ◽  
Larger Sample ◽  
Tissue Effect ◽  
Breast Thickness

Purpose: To determine whether breast thickness decreases with menopause after the reduction of glandular tissue. We also wanted to know how the decrease in breast thickness affects the compression force and the average glandular dose. Methods: In this project, we collected data regarding the compression force, breast thickness and mean glandular dose of 300 patients who had mammographic imaging in two views: CC (craniocaudal) and MLO (mediolateral oblique) view. The data were divided into three age groups: 100 patients aged 50 to 55, 100 patients aged 60 to 65 and 100 patients aged 70 to 75 years. We used basic statistical tests for measurement purposes, while we used the Shapiro–Wilk test to check normality and the Kruskal–Wallis test to compare the differences. Results and discussion: We presented the results and comparisons in the tables and box plot graphs for CC and MLO views of the left and right breast for compression force, breast thickness and MGD. In the CC view of the both breasts, we found that there were statistically signifi cant differences in thickness between groups 1 and 3, and differences in MGD between groups 1 and 2, and 1 and 3. In the MLO view of both breasts we found that compression force does not increase with the age of patients, which can be attributed to the different size and density of breasts, and different compression force. Higher compression force results in lower MGD and breast thickness. Conclusion: In the CC view of left and right breast, there is no statistically signifi cant differences in compression force, but thickness and MGD changed between some groups. In the MLO view, only MGD changed. For further research, we recommend taking measurements on a larger sample, and concurrently considering and examining other factors that may affect breast thickness, compression force and MGD.

Effectiveness of psychological interventions to improve emotion regulation in youth - a meta-analysis

2019 ◽  
Author(s):  
Bettina Moltrecht ◽  
Jessica Deighton ◽  
Praveetha Patalay ◽  
Julian Childs
Keyword(s):  
Emotion Regulation ◽  
Emotion Dysregulation ◽  
Psychological Intervention ◽  
Meta Analysis ◽  
Age Groups ◽  
Effect Sizes ◽  
What Works ◽  
Large Heterogeneity ◽  
Larger Sample

Background: Research investigating the role of emotion regulation (ER) in the development and treatment of psychopathology has increased in recent years. Evidence suggests that an increased focus on ER in treatment can improve existing interventions. Most ER research has neglected young people, therefore the present meta-analysis summarizes the evidence for existing psychosocial intervention and their effectiveness to improve ER in youth. Methods: A systematic review and meta-analysis was conducted according to the PRISMA guidelines. Twenty-one randomized-control-trials (RCTs) assessed changes in ER following a psychological intervention in youth exhibiting various psychopathological symptoms.Results: We found moderate effect sizes for current interventions to decrease emotion dysregulation in youth (g=-.46) and small effect sizes to improve emotion regulation (g=0.36). Significant differences between studies including intervention components, ER measures and populations studied resulted in large heterogeneity. Conclusion: This is the first meta-analysis that summarizes the effectiveness for existing interventions to improve ER in youth. The results suggest that interventions can enhance ER in youth, and that these improvements correlate with improvements in psychopathology. More RCTs including larger sample sizes, different age groups and psychopathologies are needed to increase our understanding of what works for who and when.

Abstract P603: Atrial Cardiopathy and Brain Infarction in Multiple Vascular Territories in the ARCADIA Trial

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Hooman Kamel ◽  
Keyword(s):  
Primary Outcome ◽  
Brain Infarction ◽  
Prevalence Ratio ◽  
Posterior Circulation ◽  
P Wave ◽  
Secondary Outcome ◽  
Vascular Territory ◽  
Brain Infarcts ◽  
Left And Right ◽  
Larger Sample

Introduction: Some embolic strokes of undetermined source (ESUS) are likely caused by occult cardiac embolism. One potential cardioembolic source is atrial cardiopathy without atrial fibrillation (AF). Patients with cardiac embolism more often have brain infarcts in multiple vascular territories than those with stroke mechanisms not involving a central embolic source. Hypothesis: In patients with ESUS, atrial cardiopathy is associated with brain infarction in multiple vascular territories. Methods: The ARCADIA trial is enrolling ESUS patients, screening them for atrial cardiopathy, and randomly assigning those with atrial cardiopathy to aspirin or apixaban. In the trial, atrial cardiopathy is defined as ≥1 of the following: P-wave terminal force >5,000 μV*ms in ECG lead V 1 , serum NT-proBNP >250 pg/mL, and left atrial diameter index ≥3 cm/m 2 on echocardiogram. Site investigators report whether the index CT or MRI showed brain infarction in the left carotid, right carotid, or posterior circulation, or some combination. In this analysis, our primary outcome was brain infarction in more than one of these three vascular territories. Our secondary outcome was infarction in both the left and right carotid territories. Results: Among 1,707 ESUS patients enrolled in ARCADIA, 679 (39.8%) met the trial’s randomization criteria for atrial cardiopathy and 213 (12.5%) had multi-territorial brain infarcts. The prevalence of brain infarction in more than one vascular territory was 14.0% in those with atrial cardiopathy versus 11.5% in those without (prevalence ratio, 1.22; 95% CI, 0.95-1.57). The prevalence of brain infarction in both the left and right carotid territories was 9.1% in those with atrial cardiopathy versus 7.4% in those without (prevalence ratio, 1.24; 95% CI, 0.90-1.70). Conclusions: These preliminary analyses from ARCADIA suggest a possible association between atrial cardiopathy and brain infarction in multiple vascular territories, but further analysis of a larger sample is needed to conclusively test whether our atrial cardiopathy definition is associated with the classic neuroimaging profile of cardiac embolism.

scholarly journals Standard reference values of weight and maximum pressure distribution in healthy adults aged 18–65 years in Germany

2020 ◽  
Vol 39 (1) ◽  
Author(s):  
D. Ohlendorf ◽  
K. Kerth ◽  
W. Osiander ◽  
F. Holzgreve ◽  
L. Fraeulin ◽  
...  
Keyword(s):  
Body Weight ◽  
Pressure Distribution ◽  
Reference Values ◽  
Effect Size ◽  
Weight Distribution ◽  
Age Groups ◽  
Healthy Adults ◽  
The Body ◽  
Maximum Pressure ◽  
Left And Right

Abstract Background The aim of this study was to collect standard reference values of the weight and the maximum pressure distribution in healthy adults aged 18–65 years and to investigate the influence of constitutional parameters on it. Methods A total of 416 healthy subjects (208 male / 208 female) aged between 18 and 65 years (Ø 38.3 ± 14.1 years) participated in this study, conducted 2015–2019 in Heidelberg. The age-specific evaluation is based on 4 age groups (G1, 18–30 years; G2, 31–40 years; G3, 41–50 years; G4, 51–65 years). A pressure measuring plate FDM-S (Zebris/Isny/Germany) was used to collect body weight distribution and maximum pressure distribution of the right and left foot and left and right forefoot/rearfoot, respectively. Results Body weight distribution of the left (50.07%) and right (50.12%) foot was balanced. There was higher load on the rearfoot (left 54.14%; right 55.09%) than on the forefoot (left 45.49%; right 44.26%). The pressure in the rearfoot was higher than in the forefoot (rearfoot left 9.60 N/cm2, rearfoot right 9.51 N/cm2/forefoot left 8.23 N/cm2, forefoot right 8.59 N/cm2). With increasing age, the load in the left foot shifted from the rearfoot to the forefoot as well as the maximum pressure (p ≤ 0.02 and 0.03; poor effect size). With increasing BMI, the body weight shifted to the left and right rearfoot (p ≤ 0.001, poor effect size). As BMI increased, so did the maximum pressure in all areas (p ≤ 0.001 and 0.03, weak to moderate effect size). There were significant differences in weight and maximum pressure distribution in the forefoot and rearfoot in the different age groups, especially between younger (18–40 years) and older (41–65 years) subjects. Discussion Healthy individuals aged from 18 to 65 years were found to have a balanced weight distribution in an aspect ratio, with a 20% greater load of the rearfoot. Age and BMI were found to be influencing factors of the weight and maximum pressure distribution, especially between younger and elder subjects. The collected standard reference values allow comparisons with other studies and can serve as a guideline in clinical practice and scientific studies.

scholarly journals Prevalence and pattern of neck masses in pediatric patient: in Aseer Central Hospital, KSA

2017 ◽  
Vol 3 (4) ◽  
pp. 791
Author(s):  
Jibril Yahya Hudise ◽  
Khalid Ali Alshehri ◽  
Radeif Eissa Shamakhey ◽  
Ali Khalid Alshehri
Keyword(s):  
Pediatric Patient ◽  
Histopathological Examination ◽  
Statistical Tests ◽  
Age Groups ◽  
Neck Mass ◽  
Anatomical Location ◽  
Histopathological Diagnosis ◽  
Central Hospital ◽  
Duct Cyst ◽  
Neck Masses

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Neck masses are a common complaint in children worldwide, and constitute a major indication for surgical consultation in many pediatric surgical centers. Most of the neck masses in children are benign in their nature and clinical course. The broad spectrum of etiology of neck masses that ranged from congenital benign to acquired neoplastic lesions is varied and related to multiple factors. This retrospective study was done with the objective to assess the distribution of neck masses related to gender, age, pathology, and anatomical location of neck masses in Aseer Central Hospital. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Medical records of 62 patients with neck masses were collected from the department of pathology at Aseer Central Hospital KSA. The cases were reviewed for data on gender, age, the type of origin tissue, the type of lesion, and the anatomical location. Comparison between genders, age groups, and tissue origins were performed. All statistical tests were performed with SPSS software. We exclude thyroid, parathyroid and salivary gland masses.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Over a period of 5 years, a total of 62 patients 53.2% and women 46.8% had neck masses resected for pathological assessments. The age of presentation was ranging from 1 to 14 years. 22.6% developed in (from 1 years to 5 years old), 38.7% developed in (6 to 10 years), and 38.7% developed, in (11 to 14 years). The histopathological diagnosis of the neck masses were congenital 40.3%, inflammatory 33.9%, and malignant tumor 25.8%. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The differential diagnosis of the pediatric neck mass includes a wide array of congenital, inflammatory, benign and malignant lesions. The exact diagnosis may only be obtained by histopathological examination. In our study the most common masses in pediatric patient thyroglossal duct cyst, all midline masses are congenital.</span></p>

scholarly journals Comparison of autocorrelation between CV-RISK independent variables in groups with and without history of cardiovascular diseases

2020 ◽  
Vol 7 (11) ◽  
pp. 1626
Author(s):  
Ivany Lestari Goutama ◽  
Hendsun . ◽  
Yohanes Firmansyah ◽  
Ernawati Su
Keyword(s):  
Cardiovascular Risk ◽  
Relative Risk ◽  
Cardiovascular Diseases ◽  
Statistical Tests ◽  
Age Groups ◽  
Density Lipoprotein ◽  
P Value ◽  
Cross Sectional ◽  
Independent Variables ◽  
History Of

Background: Cardiovascular relative risk (CVRISK) is the latest cardiovascular relative risk score to evaluate the magnitude of cardiovascular risk in healthy people regardless of age and cardiovascular risk severity. The aim of the study is to determine the correlation between each independent variables of CVRISK score in individuals with and without history of cardiovascular diseases (CVD).Methods: The study design is cross-sectional study. We conducted it online through social media using Google forms from June to August 2020. Participants include all productive age groups from 16 to 60 years. The data were processed using excel and statistically tested. Descriptive data analysis uses tabulated data which is displayed in numbers or proportions (categorical) and single data distribution (numeric). Statistical association analysis uses the categorical-correlation test with 2 statistical tests that use eta on nominal-ordinal variables and contingency coefficients on nominal-nominal variables.Results: There is a strong autocorrelation between hypertension and high tryglyceride levels (p value 0.001; correlation 0.549; risks 30.14%), nutritional status and low-density lipoprotein cholesterol (LDL-C) levels in CVD group (p value 0.002; correlation 0.774; risks 59.90%) and non-CVD group (p value 0.000; correlation 0.757; risks 57.3%). Hypertension and risky LDL-C levels firmly proves a very strong correlations and significant relationship in CVD groups (p value 0.014; correlation 0.947; risks 89.68%).Conclusions: There is a correlation that varies from weak to very strong among the independent variables in the CVRISK scoring of the participants. Further research is needed to determine the potentiality of CVRISK as an early prevention in determining the cardiovascular risk of individuals with and without history of CVD.

scholarly journals Side Effects Following Administration of the First Dose of Oxford-AstraZeneca’s Covishield Vaccine in Bangladesh: A Cross-Sectional Study

2021 ◽  
Vol 13 (4) ◽  
pp. 888-901
Author(s):  
Nishat Jahan ◽  
Fahad Imtiaz Rahman ◽  
Poushali Saha ◽  
Sadia Afruz Ether ◽  
ASM Roknuzzaman ◽  
...  
Keyword(s):  
Side Effects ◽  
Rapid Development ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Post Vaccination ◽  
Long Term Follow Up ◽  
Larger Sample

In response to the raging COVID-19 pandemic, Bangladesh started its vaccine administration in early 2021; however, due to the rapid development and launch of the vaccines in the market, many people had concerns regarding the safety of these vaccines. The purpose of this study was to evaluate the side effects that were experienced by the Bangladeshi residents after receiving the first dose of the Oxford-AstraZeneca’s Covishield vaccine (ChAdOx1nCoV-19). The study was conducted using both online and printed questionnaires and the data were analysed using SPSS. The results included the responses of 474 vaccine recipients from March–April 2021. Pain at the site of injection, fever, myalgia, fatigue and headache were the most commonly reported symptoms, and the overall side effects were found to be significantly more prevalent in the younger population (p ≤ 0.05). These findings were consistent with the results indicated by the clinical trial of ChAdOx1nCoV-19. Logistic regression analysis further revealed that compared to people aged 70 years or above, the incidence of reported side effects was significantly higher in people aged 18–30 years (odds ratio (OR) = 8.56), 31–40 years, (OR = 5.05), 41–50 years (OR = 4.08), 51–60 years (OR = 3.77) and 61–70 years (OR = 3.67). In addition, a significantly higher percentage of female participants suffered from post-vaccination side effects compared to males (OR = 1.51). It was concluded that the Covishield vaccine was well-tolerated among people of different age groups. Nevertheless, further long-term follow-up study with a larger sample size is warranted to establish the long-term safety of the COVID-19 vaccine.

scholarly journals Performance in Nonword Repetition Tasks among Mandarin- English Bilingual Children in Malaysia

2020 ◽  
Vol 28 (4) ◽  
Author(s):  
Chai Ping Woon ◽  
Ngee Thai Yap ◽  
Hui Woan Lim
Keyword(s):  
Language Impairment ◽  
Short Term Memory ◽  
Age Groups ◽  
Nonword Repetition ◽  
Developmental Trend ◽  
Older Children ◽  
Development Delay ◽  
Qualitative Measure ◽  
Larger Sample ◽  
Better Than

The nonword repetition (NWR) task has been used to measure children’s expressive language skills, and it has been argued to have potential as an early language delay/ impairment detection tool as the NWR task can be conducted rather easily and quickly to obtain a quantitative as well as a qualitative measure of children’s attention to lexical and phonological information. This paper reports the performance of two NWR tasks among thirty bilingual Mandarin-English preschoolers between the age of four through six. The study indicated that performance in the NWR tasks showed a developmental trend with older children performing better than younger children. Word length also had a significant effect on performance, possibly an effect from better short-term memory capacity as the child grew older. The children also performed better in the Mandarin NWR task compared to the English NWR task. These findings suggest potential clinical applications for diagnosis of children with language impairment or at risk of language development delay. However, further studies should improve on the tasks to verify its efficacy and to obtain norms for performance with a larger sample of children at various age groups.

scholarly journals Skull asymmetries in wild boar (Sus scrofa LINNAEUS, 1758)

2019 ◽  
Vol 56 (1) ◽  
pp. e150704
Author(s):  
Pere M. Parés-Casanova
Keyword(s):  
Environmental Factors ◽  
Wild Boar ◽  
Sus Scrofa ◽  
Age Groups ◽  
The Other ◽  
Directional Asymmetry ◽  
Two Dimensional ◽  
Entire Sample ◽  
Perfect Symmetry ◽  
Left And Right

Organisms can develop different kinds of asymmetry when deviations from expected perfect symmetry occur. Among others are fluctuating asymmetry (FA) and directional asymmetry (DA). FA represents small random differences between corresponding parts on the left and right sides of an individual in bilaterally paired structures. It is thought that FA reflects an organism’s ability to cope with genetic and environmental stress during growth. DA occurs whenever one side on the plane of symmetry develops more than the other side, and has a genetic component. In this research, we examined the expression of morphological symmetry in 38 skulls of different age groups of wild boar (Sus scrofa), on their ventral aspect, using two-dimensional coordinates of 27 landmarks. Analyses showed the presence of significant FA and DA in the entire sample, detecting also distinctive differences between age groups. The obtained results show that the shape differences in different age groups could reasonably be a consequence of a response to environmental factors for FA and a masticatory lateralization for DA.

scholarly journals Palm Creases Analysis in Students and Staff of a Teaching Hospital in Kathmandu

2019 ◽  
Vol 18 (1) ◽  
pp. 51-58
Author(s):  
Nirju Ranjit ◽  
Bidur Adhikari ◽  
Rajani Shrestha ◽  
Anusuya Shrestha ◽  
Rosha Bhandari ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Closed Type ◽  
Long Time ◽  
Left And Right ◽  
Palm Print ◽  
The Individual

Introduction: Palm creases have been studied for a long time and have been recently found to be helpful in tracking underlying medical and genetic conditions. Scientific study and typing of palm prints have been found to be lacking in the Nepalese population Methods: A cross sectional study was done on 252 subjects, 153 male and 99 females, from Kathmandu, Nepal. Subjects were selected by purposive sampling from different age groups. Demographic profile including age, sex, and handedness was collected. Palm print pattern was recorded by digital photography. Each photograph was analysed visually by single observer and pattern of palm crease was noted. Variation of each crease was also noted. Results: On the basis of relation between radial longitudinal crease and proximal transverse crease, 17.3% subjects had open type of palm crease which was significantly more in females while 76.6% subjects had closed type crease which was significantly more in males. Meeting type of palm crease was found in 5.7% of subjects. On the basis of relation between proximal and distal transverse crease, normal crease type was found in 90.1% of subjects, Simian type was found in 7.7% subjects and Sydney type was found in 1.4% of subjects. The concordance of this pattern in left and right palms was found statistically significant. Conclusions: This study presented data from 252 seemingly normal healthy subjects and found that most of them had the normal with no branching, that is normal 1 and closed crease types. Most of the individual major creases were seen to be branched type.  

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