scholarly journals Classification of Childhood Glaucoma in Patients of a Government Tertiary Hospital in Manila, Philippines using the Childhood Glaucoma Research Network System

2021 ◽  
Vol 55 (1) ◽  
Author(s):  
Martin Joseph B. Babaran ◽  
Nilo Vincent DG. FlorCruz

Background. Childhood glaucoma is a rare multifactorial disease with limited information regarding the demographics and characteristics in the Filipino setting. It can be categorized via the Childhood Glaucoma Research Network Classification scheme. Objective. Determine the clinical classification of patients diagnosed with childhood glaucoma in the ophthalmology service of a government tertiary hospital in Manila, Philippines. Methods. Medical records of all patients ≤16 years-old referred to Glaucoma Section of Philippine General Hospital from January 2015 to December 2017 were reviewed retrospectively and classified. Results. One-hundred four (104) eyes in 77 children were classified. Glaucoma associated with acquired conditions was the most prevalent in 44.2% of the patients with trauma consisting of 19.5% of all patients. Primary childhood glaucoma consisted of 15.6% and juvenile open-angle glaucoma was diagnosed in 5.2%. Glaucoma following cataract surgery was noted in 7.8% of patients. Trabeculectomy was the primary surgical intervention in 22.2% of eyes, with 78.9% of eyes reaching an IOP control of <21mmHg on final follow-up. Conclusion. Glaucoma associated with acquired conditions was the most common childhood glaucoma in the patient population. Trabeculectomy was the most common surgery done. Trauma was the most prevalent cause of glaucoma from acquired conditions.

Author(s):  
Dagar Mona ◽  
Sharma Anamika

The diagnosis "Aggressive Periodontitis", defined by the International Workshop for Classification of Periodontal Diseases and Conditions in 1999, refers to the multifactorial, severe, and rapidly progressive form of Periodontitis, which primarily – but not exclusively – affects younger patients. Aggressive periodontitis have localized and generalized forms. It is currently believed that combination of bacteriologic, immunologic and hereditary factors are of major importance in the etiology of this disease. The case was of a 20 year old female and her clinical and radiographic findings were typical for generalized Aggressive Periodontitis. Treatment consisted of thorough scaling and root planing along with administration of tetracycline250 mg every six hours for three weeks, followed by surgical intervention. Keywords: Aggressive periodontitis, multifactorial disease, treatment


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e15631-e15631
Author(s):  
A. Sawaki ◽  
N. Mizuno ◽  
T. Takagi ◽  
K. Hara ◽  
T. Nakamura ◽  
...  

e15631 Background: Gastric Submucosal tumors (SMTs) were incidentally discovered esophagogastroduodenoscopy (EGD). However, they have not been studied in detail of epidemiology. Furthermore, no treatment strategy for SMTs has been established with few studies looking into long-term outcomes. The aim of this study is to clarify the clinical features and long-term outcomes of gastric SMT at a single institute for 10-year period. Methods: We performed a total of 5307 EGDs and detected 188 gastric SMTs during 1998. All clinical data including incidence, size and location in stomach were analyzed for the medical records. A retrospective review was conducted for 10-year period for 109 patients and 79 patients were excluded because of simultaneous surgery (3), disappear in follow- up EGD (27), lost of follow-up (49). Results: Gastric SMTs were detected 188 (81 males, 107 females) of 5307 patients (3.5%). Majority size of SMTs was less than 1cm (64%) and SMTs<2cm were 91%. 56% of SMTs located middle one third of stomach, and half (22%) of the remaining SMTs were detected at upper and lower one third, respectively. In 10-year follow-up, 83 of 109 patients were alive at December 2008. One patient was dead of SMT and the remaining 25 patients were dead of other disease till December 2008. Enlargement of SMT was observed in 2 of 109 SMTs (1.8%). Both of them underwent surgical resection and diagnosed as gastrointestinal stromal tumors (GIST). One patient was annually monitored by endoscopy, from 0.6cm to 1.5cm during 4 years, without recurrence for 6 years after surgical intervention. Another didn't undergo regular endoscopy, from 1.8cm to 8cm during 2 years, with recurrence, and consequently died of SMT. Conclusions: The incidence of SMTs is 3.5%, majority (91%) is small (<2cm), and frequent location is middle one third of stomach. Most of SMTs might be managed conservatively, but regular endoscopy is required. No significant financial relationships to disclose.


2020 ◽  
Vol 15 ◽  
Author(s):  
Narin Nard Carmel Neiderman ◽  
Max Chason ◽  
Anat Wengier ◽  
Oshri Wasserzug ◽  
Oren Cavel ◽  
...  

Introduction: Several surgical procedures have been described for the treatment of respiratory distress secondary to vocal fold immobility (VFI), but the contribution of posterior cordotomy (PC) to tracheostomy weaning or prevention has not been studied in depth, particularly in the acute setting. The objective of this study was to show the effectiveness of PC to relieve dyspnea, prevent the need for tracheostomy, and enable decannulation in patients with VFI. Methods: We conducted a retrospective study and reviewed the medical records of all patients whose dyspnea warranted surgical intervention from January 2013 to January 2018. Data were retrieved on epidemiology, etiology, and duration of VFI, tracheostomy dependence, success in decannulation from tracheostomy or respiratory relief, number of procedures until decannulation, and complications. Results: Twelve suitable patients were identified of whom eleven had bilateral VFI and one had unilateral VFI. Five were tracheostomy-dependent. Ten patients underwent unilateral PC, and two patients underwent bilateral PC. All the patients experienced respiratory relief, eleven after a single PC and one after two PCs. All tracheostomy-dependent patients were decannulated. The mean follow-up after PC was 24.55 months during which none of the patients required a re-tracheostomy and three patients required revision of the PC. There were no surgical complications. Postoperatively, eight patients (67%) experienced a breathy voice and three patients (25%) had dysphagia for fluids. No patient had aspiration pneumonia. Conclusions: We conclude that PC is an easy, safe, and effective procedure for tracheostomy weaning and respiratory relief in patients with VFI. A revision PC may be indicated in some patients. A breathy voice is to be expected, and a few patients will experience dysphagia to fluids that may be addressed by instructing the patient to use a fluid thickener and take small sips.


2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandhya Swarnavel ◽  
Jim Collins ◽  
Corrine Miller

Michigan has been collecting chief complaint data from emergency departments statewide to support situational awareness activities related to communicable disease since 2004. We validated the syndromic system by comparing the chief complaint data to the electronic medical records (EMR) of a tertiary hospital in southeast Michigan to better understand the utility of the system for non-communicable disease situations.Findings of this study will help determine the accuracy of the automated classification of data based on chief complaints. This study can add confidence in planning for public health preparedness activities and situational awareness.


2021 ◽  
Vol 3 (3) ◽  
pp. 1-4
Author(s):  
Vanessa Rebelo dos Santos ◽  
◽  
Carlota Ramos ◽  
Rafael Cruz ◽  
◽  
...  

Insulinomas, although rare, are the most common pancreatic functioning neuroendocrine tumors. The diagnostic workup is commonly made late in time and surgical treatment is the only curative method. Our aim was to analyze the surgical approach to pancreatic insulinomas, through a 15-year series of patients who underwent surgery for this matter. From January 2006 to December 2020, we performed a retrospective review of the medical records of all the patients who underwent surgical treatment for insulinoma. Fourteen patients with insulinoma performed surgical intervention, 78,6% were of the female gender and the mean age was 48 years (19-86 years). Four (28,6%) of the tumors were located in the head of the pancreas, 5 (35,7%) in the body and 5 (35,7%) in the tail. Complications occurred in 4 patients (28,6%) following surgery. On follow-up, there was one (7,1%) case of local recurrence, thus necessitating a new surgical intervention [1-8].


Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Aichi Chien ◽  
Michelle Hildebrandt ◽  
Geoffrey Colby ◽  
Victor Chang ◽  
Gary Duckwiler ◽  
...  

Objective: Imaging technology for unruptured intracranial aneurysms (UIA) has improved detection of such aneurysms. However, there is limited information on UIA change over time, and how to predict the rate of enlargement. The objective of this study was to quantify the accuracy of the Predicted Aneurysm Trajectory (PAT) model recently developed by Chien et al. (J Neurosurgery. 2019; Mar 1:1-11). Methods: Patients diagnosed with UIA were prospectively enrolled at the UCLA Medical Center, and followed through serial imaging. 16 UIA cases exhibiting growth across multiple follow-ups were included in this study. Prior images and medical records were collected. Characteristics relevant to the PAT model (mean ± stdev), including initial UIA size (7.26 ± 6.38), patient age (67.4 ± 9.48 yrs.), sex (4 male), history of smoking (n=5), hypothyroidism (n=4), and follow-up duration (36.5 ± 50.0 mos.) were used to predict UIA size at each follow-up. Predicted and actual UIA sizes at follow-up were compared using symmetric mean absolute percentage error (SMAPE) with percentage error ranging from 0-100%. Results: The 16 UIA cases were split by initial UIA size. For UIA smaller than 7 mm (10 cases, 23 follow-up), SMAPE = 11.13%. For UIA greater than 7 mm (6 cases, 15 follow-up), SMAPE = 8.07%. For all UIA cases (16 cases, 38 follow-up), SMAPE = 9.92%. Conclusions: The PAT model predicts the rate of enlargement for UIA, as opposed to whether or not UIA will grow. With this new sample of data, we found the predicted UIA size at follow-up to be quite accurate, deviating in the range of 10% from the actual, measured size. Patient characteristics such as the demographics and behavior included in the model influence the growth of UIA, which allows prediction of growth to optimize treatment and management in future cases.


2001 ◽  
Vol 94 (6) ◽  
pp. 946-954 ◽  
Author(s):  
Alexandre C. Carpentier ◽  
R. Todd Constable ◽  
Michael J. Schlosser ◽  
Alain de Lotbinière ◽  
Joseph M. Piepmeier ◽  
...  

Object. Functional magnetic resonance (fMR) imaging of the motor cortex is a potentially powerful tool in the preoperative planning of surgical procedures in and around the rolandic region. Little is known about the patterns of fMR imaging activation associated with various pathological lesions in that region or their relation to motor skills before surgical intervention. Methods. Twenty-two control volunteers and 44 patients whose pathologies included arteriovenous malformations (AVMs; 16 patients), congenital cortical abnormalities (11 patients), and tumors (17 patients) were studied using fMR imaging and a hand motor task paradigm. Activation maps were constructed for each participant, and changes in position or amplitude of the motor activation on the lesion side were compared with the activation pattern obtained in the contralateral hemisphere. A classification scheme of plasticity (Grades 1–6) based on interhemispheric pixel asymmetry and displacement of activation was used to compare maps between patients, and relative to hand motor dexterity and/or weakness. There was 89.4% interobserver agreement on classification of patterns of fMR imaging activation. Displacement of activation by mass effect was more likely with tumors. Cortical malformations offer a much higher functional reorganization than AVMs or tumors. High-grade plasticity is recruited to compensate for severe motor impairment. Conclusions. Pattern modification of fMR imaging activation can be systematized in a classification of motor cortex plasticity. This classification has shown good correlation among grading, brain lesions, and motor skills. This proposal of a classification scheme, in addition to facilitating data collection and processing from different institutions, is well suited for comparing risks associated with surgical intervention and patterns of functional recovery in relation to preoperative fMR imaging categorization. Such studies are underway at the authors' institution.


PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245429
Author(s):  
Abhibol Inobhas ◽  
Sunee Chansangpetch ◽  
Anita Manassakorn ◽  
Visanee Tantisevi ◽  
Prin Rojanapongpun

Purpose The effect of statins on wound healing is controversial, and their effect on trabeculectomy outcomes remains unclear. This study aimed to examine the relationship between oral statin use and trabeculectomy outcomes. Methods Medical records of patients who underwent primary mitomycin-C augmented trabeculectomy with 2 years of follow-up were reviewed. Pre- and postoperative intraocular pressures (IOP) and numbers of medications, subconjunctival 5-fluorouracil (5-FU) injections, and bleb-needling procedures were compared between statin users and nonusers. Failure was defined as an eye that failed to achieve a 20% lowering of IOP from baseline or had an IOP > 21 mm Hg, as well as an eye that required further surgical intervention, developed hypotony, or had no light perception visual acuity. Results In total, 158 subjects were enrolled, with 47 eyes from statin users and 111 eyes from statin nonusers. The 24-month cumulative probability of failure was 78.7% for statin users and 60.4% for nonusers (P = .013). Cox proportional-hazards modeling showed a significantly higher hazard risk in statin users (adjusted hazard ratio 1.61, P = .026). There were no significant between-group differences in mean IOPs or number of medications (both P > .05) at 24 months. Multivariable Poisson regression analysis that statin use was associated with increased numbers of 5-FU injections (P = .014) and bleb-needling procedures (P = .031). Conclusions This study demonstrated that oral statin use was associated with higher rates of trabeculectomy failure and increased numbers of 5-FU injections and bleb-needling procedures.


2021 ◽  
Vol 9 (07) ◽  
pp. 1068-1073
Author(s):  
Dhinakaran N. ◽  
◽  
Arul Sundaresh Kumar L. ◽  
Karthikeyan B.M. ◽  
Monisha R.M ◽  
...  

With increasing case reports of Rhino - Orbital - Cerebral Mucormycosis, a secondary infection to Post COVID condition, the present study aimed to find the occurrence of Mucormycosis across various age groups, its presence among vaccinated population, relation between hyperglycemia and mucormycosis, site of involvement of nasal/ sinus mucormycosis and the Culture based genus classification of fungal Mucormycosis. A total number of 250 patients diagnosed with either Confirmed/ Suspected Mucormycosis, a Post COVID infection were included in the study. For all the patients, their demographic data, comorbities, vaccination details, imaging findings and follow up information were obtained and statistically analyzed for the study. The results show that: a) A major of 36.4% of mucormycosis patients were found between the age range of 51 - 60 years. B) Vaccinated population is less vulnerable to COVID and its secondary infection - Mucormycosis. C) Site of involvement of Nasal/ Sinus Mucormycosis is found as a Combined Maxillary+Ethmoid+orbit involvement in 80.8% followed by Ehtmoidal involvement and palatal involvement. D) Presence of diabetes mellitus was present among 93.2% of the participants and E) The genus classification shows the occurrence of Rhizopus Arrhizus was the cause for mucormycosis found in many of the culture based fungal infection among the Post COVID patients involved in the study. The study concludes that patients treated for COVID in the age group of 30 years to 70 years are more vulnerable to acquire Mucormycosis. Glycemic control among the COVID treatment patients will grossly prevent the occurrence of Mucormycosis infection.


2005 ◽  
Vol 33 (4) ◽  
pp. 469-476 ◽  
Author(s):  
D. M. Roberts ◽  
J. F. Fraser ◽  
N. A. Buckley ◽  
B. Venkatesh

There is limited information regarding the management and outcomes of patients presenting with anticholinesterase pesticide poisoning in Australia. Patients presenting to a tertiary referral hospital with anticholinesterase exposures were identified by discharge coding. The medical records of each patient were retrospectively reviewed. Based on clinical outcome, patients were classified as severe or non-severe poisonings. Forty-one presentations were noted between 1990 and 2003. Eight patients (20%) had severe poisoning of which tachycardia, fasciculations with weakness and metabolic acidosis were common manifestations. The diagnosis was delayed in four patients due to the absence of a clear history, which did not influence patient outcomes or put hospital staff at risk of nosocomial poisoning. The median length of hospital stay was prolonged in severe poisonings (20 days) compared to 12 hours in other patients. Two cases of intermediate syndrome were attributed to fenthion and diazinon, and one case of delayed polyneuropathy to trichlorfon. Cholinesterase activities were performed in only 49% of presentations. The overall mortality was 2.4% (1 death) and the mortality in patients with severe poisoning was 12.5%. The incidence of anticholinesterase poisoning in Australia is low. These outcomes were favourable and comparable with other published data. Measures to enhance the knowledge of medical staff supplemented by validated treatment protocols should be developed. For less significant exposures, an emphasis on adequate documentation of cholinergic signs and cholinesterase activities is necessary for rapid triage and may also have potential forensic implications if not performed.


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