Effect of Targeted Nursing on Nutritional Status and Disease Recovery of Patients with Pulmonary Tuberculosis

2021 ◽  
2015 ◽  
Vol 55 (1) ◽  
pp. 7
Author(s):  
Fadilah Harahap ◽  
Ridwan M. Daulay ◽  
Muhammad Ali ◽  
Wisman Dalimunthe ◽  
Rini Savitri Daulay

Background Tuberculosis (TB) infection is highly prevalent in Indonesia. The source of transmission of TB to a child is usually via an adult with sputum smear-positive pulmonary tuberculosis. The Mantoux test is a diagnostic tool for tuberculosis infection. The BCG vaccine has been used for the prevention of TB, but its efficacy is still debated. Objective To assess for an association between Mantoux test results and BCG vaccination in children who had contact with adult pulmonary tuberculosis and to assess for differences in Mantoux test induration with regards to nutritional status, age, type of TB contact, and time duration since BCG vaccination in BCG-vaccinated and BCG-unvaccinated children. Methods A cross-sectional study was conducted in FebruaryMarch 2011 on infants and children (aged 3 months to five years), who had household contact with adult pulmonary TB. We performed tuberculin (Mantoux) skin tests to detect TB infection in the children. Subjects were consisted of two groups: BCG-vaccinated and BCG-unvaccinated. Results Subjects were 100 children (50 BCG-vaccinated and 50 BCG-unvaccinated subjects). Positive Mantoux test results were observed in 9 vaccinated subjects and 33 unvaccinated subjects. The mean diameters of induration in the vaccinated and unvaccinated groups were 7.6 mm and 9.6 mm, respectively (95%CI of difference -4.25 to 0.20; P=0.074). In children who had household contact with sputum smear-positive adult pulmonary TB, BCG vaccination was a protective factor against TB infection, with an odds ratio (OR) of 0.113 (95%CI 0.045 to 0.286; P=0.0001). There were no significant differences in Mantoux test induration associated with nutritional status, age, type of TB contact, and duration since BCG vaccination, between the two groups. Conclusion BCG vaccination has a protective effect on TBexposed children, based on Mantoux test results. However, there are no differences in Mantoux test induration associated with nutritional status, age, type of TB contact, or duration since BCG vaccination, between the BCG-vaccinated and BCGunvaccinated groups.


2021 ◽  
Vol 1 (2) ◽  
pp. 538-547
Author(s):  
Fitri Zulfa Hayati ◽  
Nurhapipa Nurhapipa ◽  
Nila Puspita Sari

Tuberkulosis Paru merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Kejadian penyakit Tuberkulosis Paru di Puskesmas Rejosari Kota Pekanbaru merupakan kasus tertinggi di kota pekanbaru sebanyak 798 kasus. Tujuan penelitian ini secara umum untuk mengetahui hubungan kondisi fisik rumah dan status gizi dengan insiden penyakit tuberkulosis paru. Penelitian ini adalah analitik kuantitatif dengan pendekatan Case Control. Populasi kasus dalam penelitian ini yaitu seluruh penderita Tuberkulosis Paru. Sampel penelitian yaitu 18 responden kelompok kasus dan 72 responden kelompok kontrol dengan menggunakan teknik Simple random sampling. Lokasi penelitian dilakukan di Wilayah Kerja Puskesmas Rejosari Kota Pekanbaru pada bulan Juli – Agustus 2020. Alat ukur yang digunakan yaitu kuesioner, roll meter, lux meter, dan timbangan berat badan. Analisis data dilakukan secara univariat dan bivariat menggunakan uji Chi Square. Hasil uji statistik hubungan dari setiap variabel semuanya berhubungan dengan insiden penyakit tuberkulosis paru, yaitu variabel luas ventilasi (p = 0,002, OR = 7,857), kepadatan hunian (p = 0,003, OR = 5,500), pencahayaan (p = < 0,05, OR = 8,500), dan status gizi (p = 0,001, OR = 10,818). Diharapkan kepada tim pencegah dan pengendalian penyakit tuberkulosis paru Puskesmas Rejosari meningkatkan penyuluhan atau pemahaman langsung kepada masyarakat penderita TB paru serta membentuk dan melatih kader – kader untuk penanggulangan Tuberkulosis Paru. Diharapkan masyarakat selalu membuka jendela agar udara dan cahaya dapat masuk ke dalam rumah serta menjaga pola makan yang seimbang dan sehat. Pulmonary Tuberculosis is an infectious disease caused by the bacteria Mycobacterium tuberculosis. The incidence of pulmonary tuberculosis in Rejosari Primary Health Center Pekanbaru City is the highest case in Pekanbaru city with 798 cases. The purpose of this study in general was to determine the relationship between the physical condition of the house and nutritional status with the incidence of pulmonary tuberculosis. This research is a quantitative analytic with a Case Control approach. The populations of cases were all patients with pulmonary tuberculosis. The research sample was 18 respondents in the case group and 72 respondents in the control group using the simple random sampling technique. The research location was carried out in the Rejosari Public Health Center, Pekanbaru City in July - August 2020. The measuring instruments used were questionnaires, roll meters, lux meters, and weight scales. Data analysis was performed univariate and bivariate using the Chi Square test. The statistical test results of the relationship between each variable were all related to the incidence of pulmonary tuberculosis, namely the variable area of ventilation (p = 0.002, OR = 7.857), occupancy density (p = 0.003, OR = 5,500), lighting (p =0.05, OR 8.5)and nutritional status (p = 0.001, OR = 10.818). It is hoped that the team for preventing and controlling pulmonary tuberculosis at the Rejosari Community Health Center will increase direct education or understanding to people with pulmonary tuberculosis and form and train cadres to control pulmonary tuberculosis. It is hoped that people will always open windows so that air and light can enter the house and maintain a balanced and healthy diet.


PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e77979 ◽  
Author(s):  
Anurag Bhargava ◽  
Madhuri Chatterjee ◽  
Yogesh Jain ◽  
Biswaroop Chatterjee ◽  
Anju Kataria ◽  
...  

2021 ◽  
Vol 4 (5) ◽  
pp. 20536-20548
Author(s):  
Bianca Oliveira Da Silva ◽  
Denise Karulynne de Sousa Silva ◽  
Fapríscia Gomes De Souza ◽  
Suele dos Santos Benício ◽  
Isameriliam Rosaulem Pereira Da Silva ◽  
...  

Biomedicine ◽  
2021 ◽  
Vol 41 (1) ◽  
pp. 36-41
Author(s):  
Aishwarya G. Warrier ◽  
Reshma Kumarchandra ◽  
Kuthethur Sudha ◽  
Bhat B. Jayashree ◽  
Yalla Durgarao

Introductionand Aim: Etiopathogenesis of Pulmonary tuberculosis(PTB), is well established. Yet, the mechanisms by which a treatment regimen brings about remodelling of the pulmonary tissue during recovery phase is not well understood. The involvement of matrix metalloproteinase in this regard is debated, due to its dual role, either in disseminating the disease due to lung cavitation or reducing the inflammation due to recruitment of macrophages to the lung granulomas. PTB is a disease also driven by undernourishment.This study focuses on the association of nutritional status of PTB patients in restoring healthy lung tissue, monitored by blood levels of albumin, iron and MMP9, during the course of intensive treatment. Materials and Methods: Serum levels of MMP9, iron, Total protein and albumin were estimated in 30 PTB patients who visited the Directly Observed Treatment Short course (DOTS) Centre at Government Wenlock Hospital, Mangalore, Karnataka,India. Twenty controls were enrolled for comparative statistics. Samples were collected at baseline and after two months of DOTS treatment in case of patients.Pre-treatment and post treatment values were compared by paired t test.Student’s ‘t’ test was used for comparing parameters in controls and patients. Correlation between parameters was done by Pearson’s correlation test.   Results: A significant increase was observed in serum iron (P=0.002) and total protein(P=0.01) levels post treatment but there was no significance in the levels of MMP9. Further, serum MMP9 correlatednegatively with body weight, BMI and serum total protein levels, post treatment, which was statistically significant. No other correlations were significant. Conclusion: We conclude that MMP9 neither seems to be a diagnostic marker nor a therapeutic target in the treatment of tuberculosis. Although serum iron appears to be a predictor of improved nutritional status post treatment, it probably may have a role in tissue remodelling independent of MMP-9.


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