scholarly journals Comparative Study of the Effect of Three Different Interocclusal Recording Materials on Reproducibility of Horizontal Condylar Registrations in Two Different Semiadjustable Articulators: A Clinical Study

2011 ◽  
Vol 1 (3) ◽  
pp. 155-162 ◽  
Author(s):  
Ajay Sharma ◽  
Lavanya Ajay Sharma ◽  
NS Azhagarasan ◽  
Chitra Shankar
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Clinical Studies ◽  
Signs And Symptoms ◽  
Mechanical Device ◽  
Jaw Movements ◽  
Recording Material ◽  
Custom Made ◽  
Healthy Female ◽  
Interocclusal Records

ABSTRACT Purpose Simulation of jaw movements in an articulator requires one of the important condylar parameters, i.e. horizontal condylar inclination (HCI) to be registered in the patient and transferred to a mechanical device (articulator). The most popular and commonly used technique to determine horizontal condylar inclination (HCI) is by use of interocclusal records. Clinical studies comparing the effects of different interocclusal recording materials on reproducibility of protrusive settings in semiadjustable articulators have not been studied much. Hence, the present clinical study was conducted to comparatively assess the effects of three commonly used interocclusal recording materials; namely wax, polyvinylsiloxane, polyether in obtaining HCI values in two commonly used semiadjustable articulators; namely Hanau Wide-Vue (arcon) and Dentatus ARH type (non-arcon). Materials and methods One healthy female patient with intact dentition and no signs and symptoms of TMJ problems was selected for the study. With the help of a custom-made protrusive guide, 10 individual protrusive records for each of the interocclusal recording materials were made. These records were used for programming the two articulators and the respective HCI values were noted. The results obtained were tabulated and subjected to statistical analysis. Results The HCI values obtained using each of the interocclusal recording materials in both the semiadjustable articulators was found to be statistically significant. Among the materials polyether gave the highest values with less variability and wax gave low values with greater variation. Conclusion The results of this study indicate that HCI values vary both according to the type of interocclusal recording material employed and the articulator selected.

scholarly journals A Comparative Evaluation of the Retention of Denture Bases fabricated using Selective Pressure, Massad's and Functional Impression Techniques: A Clinical Study

2014 ◽  
Vol 4 (3) ◽  
pp. 139-144
Author(s):  
Ragini Sudhakar Sanaye
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Comparative Evaluation ◽  
Selective Pressure ◽  
P Value ◽  
Denture Base ◽  
Significance Level ◽  
Impression Technique ◽  
Custom Made ◽  
The Difference

ABSTRACT Background Impression techniques have evolved considerably during the last decade. However, it needs to be assessed whether the retention achieved with these techniques is adequate enough to establish them as an alternative to the conventional techniques. Purpose This study was planned to evaluate the retention of denture bases fabricated using the selective pressure, functional and Massad's impression techniques. Materials and methods Twenty completely edentulous patients were selected and each of them was subjected to three definitive impression techniques: selective pressure, functional and Massad's techniques. The permanent bases were fabricated and checked for retention with a custom made retention checking apparatus. The load required to dislodge the denture base fabricated using each technique, from the maxillary foundation was recorded and this data was subjected to statistical analysis. Results The statistical analysis shows that the difference between the selective pressure and the functional impression technique is statistically significant (p = 0.046) However, this result needs verification by collecting more data or designing another study, since the observed p-value is closer to the significance level (i.e. 0.05). Though the difference between the means of Massad's and functional techniques is of 39 gm, it is statistically not significant (p = 0.09). The difference between means load to dislodge denture bases for selective pressure and Massad's techniques (5.5 gm) is not statistically significant (p = 0.95). Conclusion The three impression techniques yielded adequately retentive permanent denture bases. However, retention of the denture bases obtained from the selective pressure impression technique was best, followed by the Massad's and functional techniques. Clinical implication The results of this study indicated that the denture bases fabricated using selective pressure impression technique were more retentive than the Massad's and the Functional impression technique. How to cite this article Sanaye RS, Shah N, Ram SM. A Comparative Evaluation of the Retention of Denture Bases fabricated using Selective Pressure, Massad's and Functional Impression Techniques: A Clinical Study. J Contemp Dent 2014;4(3):139-144.

scholarly journals Clinical Study on the Effectiveness of Pippali Khanda in the Management of Amlapitta

2017 ◽  
Vol 8 (3) ◽  
Author(s):  
Richa Singh ◽  
Girish KJ ◽  
Yadu Narayana Mooss
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Gastrointestinal Tract ◽  
Ordinal Data ◽  
Signs And Symptoms ◽  
Dosage Forms ◽  
Dietary Habit ◽  
Bonferroni Correction ◽  
Signed Rank ◽  
Post Hoc

Background: Amlapitta (Acid peptic disorder) is disease of the Annavaha Srotas (gastrointestinal tract) which results primarily because of indulgence in Ahita Ahara Vihara Sevana (irregular dietary habit and day to day activity). Khanda (sugar granules) is widely acceptable dosage forms in the present scenario due its palatability, shelf life and easy administration. The selected drug Pippali Khanda possesses Deepana (enhances digestion), Pachana (digestive) and Vatanulomana (regulates Vata). Study has been undertaken to evaluate the effectiveness of Pippali Khanda in the management of Urdhvaga Amlapitta having dominance of Kapha and Pitta Dosha. Methods: Among the 32 registered patients 30 of them completed the course of treatment. Pippali Khanda was administered in a dose of three gram twice daily, fifteen minutes after food, for fifteen days. Patients were assessed before, end of first of week and 15th day of treatment. For statistical analysis, ordinal data were assessed by Friedman’s test and Wilcoxon signed rank as Post Hoc after applying Bonferroni correction. Results: There were statistically highly significant improvements in the signs and symptoms of Amlapitta. (p<0. 05) observed. Conclusion: Pippali Khanda is effective and useful in the management of signs and symptoms of Amlapitta besides improved the parameters of Agni and digestion.  

A Clinical Study to evaluate Pragbhakta and Adhobhakta Bhaishajya Kala in Janu Sandhigata Vata

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Yamuna S. Reddy ◽  
K Savitha R. Shenoy ◽  
Sri Nagesh KA
Keyword(s):  
Clinical Trial ◽  
Statistical Analysis ◽  
Clinical Study ◽  
Treatment Success ◽  
Signs And Symptoms ◽  
Therapeutic Effects ◽  
Important Principle ◽  
Group A ◽  
Group B

Bhaishajya Kala is an important principle in our classics, which is to be considered while treating a disease. During treatment, success can be achieved only when there is proper combination of Desha, Kala, Pramana, Satmya, Asatmya, Pathya and Apathya. [1] Among these seven, Kala is given second position which reflects importance of Kala in Chikitsa. The relation between Aushadha and Kala is well established in classics. Acharya Charaka states that “medicine administered at appropriate Kala is more efficacious than one given in inappropriate Kala. ”[2] To highlight its role in Chikitsa, there is a necessity to analyze this concept which is the need of the hour. With the intention of practically validating this concept “Janu Sandhigatavata” has been taken up for the study. Panchatikta Guggulu Ghrita which has been taken for the study is seen to have beneficial therapeutic effects on Sandhigatavata as evidently seen in the Phalashruti. [3] As Bhaishajya Kala is not specifically mentioned for any Vatavyadhi so also for Janu Sandhigatavata, this study intends to find the appropriate Bhaishajya Kala for the same. Among all the Bhaishajya Kalas, in the present study only two Kalas were taken up which were suitable for Janu Sandhigatavata. The clinical trial was carried out on 40 patients. They were divided into two groups Group A and Group B consisting of 20 patients each. The results were analyzed based on the signs and symptoms. Statistical analysis between Group A and Group B for the parameters Sandhi Shoola, Shotha, Prasaranaakunchanyo Vedana, ROM and VAS painscale found no significant changes in the group. Individually each Group had highly significant results. But in the observation parameter of Atopa there was a difference of value between the groups, Group A was higher than Group B.

scholarly journals A COMPARATIVE CLINICAL STUDY ON MATRA BASTI WITH BALA TAILA AND SAHACHARA TAILA

2021 ◽  
Vol 9 (11) ◽  
pp. 2644-2651
Author(s):  
Yadukrishnan V. P ◽  
Praveen B. S
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Pain Score ◽  
Lower Limb ◽  
Severe Pain ◽  
Signs And Symptoms ◽  
The Body ◽  
Lumbar Region ◽  
Comparative Clinical Study ◽  
Good Improvement

Basti is said to be the best therapy for pacifying aggravated Vata Dosha. It is considered as Ardha Chikitsa due to the capacity to cure diseases of either Abhyantara, Bahya or Madhyama Roga Marga when used judiciously. It is broadly classified into Niruha, Anuvasana and Uttara Basti Anuvasana Basti believed to nourish the body and increase Bala (strength) and Varna (complexion). Matra Basti is a type of Anuvasana Basti in which the Sneha is administered in the lowest dosage. Gridhrasi is one among Vataja Nanatmaja Vikara characterised by Stabdhata (stiffness), Vedana (pain), Toda (pricking sensation) in the lumbar region radiating to the lower limb. Gridhrasi is of two types viz Vataja and Vata Kaphaja Gridhrasi. Vataja Gridhrasi is characterized by severe pain whereas, Vata Kaphaja Gridhrasi has symptoms viz Tandra (drowsiness), Gaurava (heaviness of body) and Aruchi (ano- rexia). Bala Taila contains Madhura Rasa, Snigdha, Vatahara, Balya, Brumhana properties. Sahachara Taila contains Madhura Tikta Rasa, Ushna Veerya and Vata-Kaphahara properties. This study was undertaken to com- pare the efficacy of Matra Basti with Bala Taila and Sahachara Taila in the management of Gridhrasi to ascer- tain a better modality. Statistical analysis showed that both groups showed good improvement in various parame- ters of Gridhrasi. When compared between the groups it revealed that there was not statistically difference except in S Lanss Pain Score (p<0.05). Hence it can be concluded that both Bala Taila Matra Basti and Sahachara TailaMatra Basti may be practiced in treating patients with Gridhrasi (Sciatica) to reduce both signs and symptoms successfully. Keywords: Matra Basti, Gridhrasi, Bala Taila, Sahachara Taila

Clinical Study of Shirishadi tablet in the management of Tamaka Shvasa w.s.r. to Bronchial Asthma

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Pankaj Chhayani ◽  
Hemang Raghavani ◽  
Dhananjay Patel
Keyword(s):  
Internal Medicine ◽  
Clinical Study ◽  
Side Effects ◽  
Bronchial Asthma ◽  
Medical Science ◽  
Signs And Symptoms ◽  
Effective Remedy ◽  
All Diseases

Tamaka Shvasa is described as a most difficult to cure (Yapya) among all diseases in Ayurveda. In present study Tamaka Shvasa is correlated with Bronchial Asthma because of its symptomatology is much similar with Tamaka Shvasa. In modern medical science, steroids and bronchodilators are mainly used for its management, but they cause certain side effects. Present study was undertaken to provide safe and effective remedy for Tamaka Shvasa through Ayurvedic medicaments. Shirishadi tablet was given as internal medicine for 30 days. Upto 60% relief was found in signs and symptoms of Tamaka Shvasa.

scholarly journals Robust Step Detection from Different Waist-Worn Sensor Positions: Implications for Clinical Studies

2020 ◽  
Vol 4 (1) ◽  
pp. 50-58
Author(s):  
Matthias  Tietsch ◽  
Amir Muaremi ◽  
Ieuan Clay ◽  
Felix Kluge ◽  
Holger Hoefling ◽  
...  
Keyword(s):  
Clinical Study ◽  
Clinical Studies ◽  
Neurological Diseases ◽  
Human Gait ◽  
Robust Solution ◽  
Step Detection ◽  
Study Protocols ◽  
Study Results ◽  
Wide Range ◽  
The Impact

Analyzing human gait with inertial sensors provides valuable insights into a wide range of health impairments, including many musculoskeletal and neurological diseases. A representative and reliable assessment of gait requires continuous monitoring over long periods and ideally takes place in the subjects’ habitual environment (real-world). An inconsistent sensor wearing position can affect gait characterization and influence clinical study results, thus clinical study protocols are typically highly proscriptive, instructing all participants to wear the sensor in a uniform manner. This restrictive approach improves data quality but reduces overall adherence. In this work, we analyze the impact of altering the sensor wearing position around the waist on sensor signal and step detection. We demonstrate that an asymmetrically worn sensor leads to additional odd-harmonic frequency components in the frequency spectrum. We propose a robust solution for step detection based on autocorrelation to overcome sensor position variation (sensitivity = 0.99, precision = 0.99). The proposed solution reduces the impact of inconsistent sensor positioning on gait characterization in clinical studies, thus providing more flexibility to protocol implementation and more freedom to participants to wear the sensor in the position most comfortable to them. This work is a first step towards truly position-agnostic gait assessment in clinical settings.

scholarly journals Development and content validity of the Barth Syndrome Symptom Assessment (BTHS-SA) for adolescents and adults

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Chad Gwaltney ◽  
Jonathan Stokes ◽  
Anthony Aiudi ◽  
Iyar Mazar ◽  
Sarah Ollis ◽  
...  
Keyword(s):  
Clinical Studies ◽  
Genetic Disorder ◽  
Signs And Symptoms ◽  
Symptom Assessment ◽  
Barth Syndrome ◽  
Therapeutic Area ◽  
Symptom Experience ◽  
Patient Reported ◽  
Adolescents And Adults ◽  
Syndrome Symptom

Abstract Background Barth Syndrome (BTHS) is a rare genetic disorder that presents as a complex of debilitating symptoms and reduced life expectancy. Well-developed, BTHS-specific assessments measuring primary signs and symptoms of BTHS are not currently available, making it difficult to evaluate treatment effects in BTHS clinical studies. The objective of this research was to develop symptom-focused patient-reported outcome (PRO) measures for use in clinical studies with adolescents and adults with BTHS. Methods Concept elicitation interviews (CEIs) with pediatric (n = 18, age < 16 years) and adult (n = 15, age ≥ 16 years) individuals with BTHS and/or their caregivers were conducted to identify signs and symptoms relevant to BTHS and important to individuals with the condition. Based on CEI results, questionnaire construction activities were conducted to create unique adolescent and adult versions of the Barth Syndrome-Symptom Assessment (BTHS-SA). The questionnaires were evaluated in cognitive debriefing interviews (CDIs) with adolescents (n = 12; age 12- < 16 years) and adults (n = 12; age ≥ 16 years) with BTHS to assess relevance and readability of the tools. Results During the CEIs, a total of 48 and 40 signs and symptoms were reported by the pediatric and adult groups, respectively; 31 were reported by both age groups. Fatigue/tiredness and muscle weakness were the symptoms most frequently reported by both pediatric and adult patients with BTHS as important to improve with an effective treatment. The CEI results informed construction of a nine-item version of the BTHS-SA for adolescents and an eight-item version for adults. Developed for daily administration, each version asks respondents to rate symptom severity “at its worst” over the 24 h prior to administration. CDIs with both adolescents and adults with BTHS demonstrated that each BTHS-SA version was reflective of the disease experience and that respondents could interpret the questionnaire as intended and provide responses that accurately reflected their symptom experience. Conclusions The BTHS-SA adolescent and adult versions are content-valid PRO measures that can be used to evaluate severity of disease-specific symptoms in future clinical trials. Given the lack of available and well-developed assessments in this underserved therapeutic area, these tools fulfill a need for clinical researchers developing treatments for individuals with BTHS.

scholarly journals A Concise Review of Silver Diamine Fluoride on Oral Biofilm

2021 ◽  
Vol 11 (7) ◽  
pp. 3232
Author(s):  
Jingyang Zhang ◽  
Sofiya-Roksolana Got ◽  
Iris Xiaoxue Yin ◽  
Edward Chin-Man Lo ◽  
Chun-Hung Chu
Keyword(s):  
Clinical Study ◽  
Streptococcus Mutans ◽  
Bacterial Adhesion ◽  
Clinical Studies ◽  
Antibacterial Properties ◽  
Tooth Surface ◽  
Original Research ◽  
Laboratory Studies ◽  
Oral Biofilm ◽  
Silver Diamine Fluoride

Studies have shown that silver diamine fluoride (SDF) is an effective agent to arrest and prevent dental caries due to its mineralizing and antibacterial properties. While plenty of studies have investigated the mineralizing properties, there are few papers that have examined its antibacterial effect on oral biofilm. The objective of this study was to identify the effect of silver diamine fluoride on oral biofilm. Method: The keywords used were (silver diamine fluoride OR silver diammine fluoride OR SDF OR silver fluoride OR AgF AND biofilm OR plaque). Two reviewers screened the titles and abstracts and then retrieved the full text of the potentially eligible publications. Publications of original research investigating the effect of SDF on oral biofilm were selected for this review. Results: This review included 15 laboratory studies and six clinical studies among the 540 papers identified. The laboratory studies found that SDF could prevent bacterial adhesion to the tooth surface. SDF also inhibited the growth of cariogenic bacteria, including Streptococcus mutans, Lactobacillus acidophilus, Streptococcus sobrinus, Lactobacillus rhamnosus, Actinomyces naeslundii, and Enterococcus faecalis, thus contributing to its success in caries arrest. One clinical study reported a decrease in Streptococcus mutans and Lactobacillus sp. in arrested caries after SDF treatment, and another clinical study found that SDF inhibited the growth of periodontitis microbiota, including Porphyromonas gingivalis, Tannerella forsythia, and Prevotella intermedia/nigrescens. However, three clinical studies reported no significant change in the microbial diversity of the plaque on the tooth after SDF treatment. Moreover, one laboratory study and one clinical research study reported that SDF inhibited the growth of Candida albicans. Conclusion: Not many research studies have investigated the effects of SDF on oral biofilm, although SDF has been used as a caries-arresting agent with antibacterial properties. However, a few publications have reported that SDF prevented bacterial adhesion to the teeth, inhibited the growth of cariogenic and periodontal bacteria, and possessed antifungal properties.

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