Minimizing stress with remifentanil in a patient with Takotsubo undergoing ophthalmic surgery

2016 ◽  
Vol 12 (1) ◽  
pp. 86 ◽  
Author(s):  
Sbaraglia Fabio, MD ◽  
Garra Rossella, MD ◽  
De Riso Mariella, MD ◽  
Continolo Nicola, MD ◽  
Sammartino Maria, MD
Keyword(s):  
Anxiety Disorder ◽  
Preoperative Assessment ◽  
Protective Role ◽  
Respiratory Drive ◽  
Takotsubo Syndrome ◽  
Ophthalmic Surgery ◽  
Free Condition ◽  
Relative Rarity ◽  
Positive Effect

Anesthesiological management of patients with Takotsubo syndrome (TTS) is a challenge of questions related to physiopathology, prognosis, and trigger causes. Relative rarity of this disease and lack of wide literature do not allow to state any negative or positive effect of the variety of drugs available for anesthesia. The authors report a case of a woman with a clear diagnosis of TTS and anxiety disorder, who underwent to cataract extractions at both eyes at two different times. Clinical management is described, from preoperative assessment until discharge of the patient. In both cases, surgery was successfully performed using remifentanil Target Controlled Infusion sedation in spontaneous ventilation. In this article, the authors suggest the possible cardio-protective role of remifentanil in this kind of pathology, focusing on its advantageous sedating action that guarantees a stress-free condition, while maintaining control on respiratory drive.

Does caffeine improve respiratory rate during remifentanil target controlled infusion sedation? A case report in endoscopic sedation

2017 ◽  
Vol 13 (2) ◽  
pp. 125 ◽  
Author(s):  
Fabio Sbaraglia, MD ◽  
Mariella De Riso, MD ◽  
Maria Elena Riccioni, MD ◽  
Guido Costamagna, MD ◽  
Maria Sammartino, MD
Keyword(s):  
Respiratory Rate ◽  
Protective Role ◽  
Respiratory Center ◽  
Respiratory Drive ◽  
Remifentanil Infusion ◽  
Impaired Patient ◽  
Target Controlled Infusion ◽  
Therapeutic Colonoscopy ◽  
Positive Effect ◽  
Neonatal Apnea

Sedation for endoscopic procedures may be challenging when facing patients with high risk. Traditional techniques, as propofol or meperidine/midazolam administration, cannot ensure an adequate level of safety and efficacy for these patients. Remifentanil infusion is a common alternative, but the incidence of apneic events does not allow achieving safely a good level of analgesia. To overcome with this issue, the authors borrowed suggestions from other medical fields. The clinical practice has recognized a wide utility of methylxanthines (caffeine, theophylline, etc). The positive effect of caffeine on the airways function is known and in the treatment of neonatal apnea, it works as direct stimulant of central respiratory center. Furthermore, preclinical studies suggest that methylxanthines could have a protective role on the opioids inhibition of the bulbar-pontine respiratory center. As described in this report, the authors observed that, also when apnea has been induced by remifentanil, caffeine is able to restore the respiratory rate. The authors present the management of a respiratory impaired patient scheduled for a therapeutic colonoscopy. Our sedation was focused on the match between remifentanil in target controlled infusion and intravenous caffeine, like an “expresso to wake-up” the respiratory drive.

De invloed van geïdealiseerde mediabeelden op het zelfbeeld van jonge meisjes

2011 ◽  
Vol 39 (3) ◽  
Author(s):  
Frederieke S. van der Deen ◽  
Saskia A. Schwinghammer ◽  
Kirsten T. Verkooijen
Keyword(s):  
Protective Role ◽  
The Self ◽  
Media Images ◽  
Young Girls ◽  
Self Image ◽  
Beauty Ideal ◽  
Positive Effect ◽  
Moderating Role

The influence of idealised media images on the self-image of young girls: The positive moderating role of media awareness The influence of idealised media images on the self-image of young girls: The positive moderating role of media awareness This study examines the influence of idealised (extremely attractive) models appearing in beauty advertisements on the self-image of 10-13 year-old girls and investigates the possible protective role of media awareness. Model attractiveness (idealised vs. normally attractive) and media awareness (induced vs. not induced) were manipulated and self-image and internalisation of the Western beauty ideal were measured. Results show that after exposure to beauty advertisements with idealised models, girls with higher induced media awareness had a slightly more positive self-image than girls in whom media awareness was not induced. Moreover, this positive effect of media awareness was more pronounced within the group of girls who highly internalized the Western beauty ideal. It is concluded that media awareness can protect the self-image of young (vulnerable) girls who are exposed to idealised media images.

scholarly journals Ameliorative effect of vitamin C on cypermethrin-induced hepatotoxicity and renal malfunction of adult male rats.

2021 ◽  
Vol 14 ◽  
pp. 1-15
Author(s):  
Nessrin Kheirallah ◽  
Hussein K. Hussein ◽  
Horeya Abd El Gawad ◽  
Basma Youssef
Keyword(s):  
Vitamin C ◽  
Protective Role ◽  
Male Rats ◽  
Glucose Levels ◽  
Stress Markers ◽  
Ameliorative Effect ◽  
Liver And Kidney ◽  
Kidney Functions ◽  
Positive Effect

Cypermethrin is a widely used insecticide belongs to type II pyrethroids. It is highly used in developing countries to control many species of insects as it plays an important role in pest control. Vitamin C is an important intracellular antioxidant against insecticides. The aim of the present study is to analyze the toxic effects of cypermethrin (CYP) and the positive effect of vitamin C (VC) with graded doses (0 CYP, 200 VC, 12 CYP and 12 CYP+200 VC mg/kg body weight of male rats/day) for 30 days on liver and kidney functions. Moreover, antioxidant enzymes, oxidative stress markers, glycogen and glucose levels and also serum lipid profile were studied. Also, this study aimed to evaluate the possible protective role of vitamin C against cypermethrin toxicity

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

Parenting Behaviors and Anxiety in Young Adults

2015 ◽  
Vol 36 (3) ◽  
pp. 170-176 ◽  
Author(s):  
Erin N. Stevens ◽  
Joseph R. Bardeen ◽  
Kyle W. Murdock
Keyword(s):  
Effortful Control ◽  
Parenting Behaviors ◽  
Protective Role ◽  
Anxiety Symptoms ◽  
Interactive Effects ◽  
Parental Overprotection ◽  
High Control ◽  
Development Of Anxiety ◽  
The Relationship

Parenting behaviors – specifically behaviors characterized by high control, intrusiveness, rejection, and overprotection – and effortful control have each been implicated in the development of anxiety pathology. However, little research has examined the protective role of effortful control in the relation between parenting and anxiety symptoms, specifically among adults. Thus, we sought to explore the unique and interactive effects of parenting and effortful control on anxiety among adults (N = 162). Results suggest that effortful control uniquely contributes to anxiety symptoms above and beyond that of any parenting behavior. Furthermore, effortful control acted as a moderator of the relationship between parental overprotection and anxiety, such that overprotection is associated with anxiety only in individuals with lower levels of effortful control. Implications for potential prevention and intervention efforts which specifically target effortful control are discussed. These findings underscore the importance of considering individual differences in self-regulatory abilities when examining associations between putative early-life risk factors, such as parenting, and anxiety symptoms.

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