scholarly journals Experimental immunology Oral administration of Aloe vera gel, anti-microbial and anti-inflammatory herbal remedy, stimulates cell-mediated immunity and antibody production in a mouse model

2014 ◽  
Vol 2 ◽  
pp. 125-130 ◽  
Author(s):  
Barbara Joanna Bałan ◽  
Marcin Niemcewicz ◽  
Janusz Kocik ◽  
Leszek Jung ◽  
Ewa Skopińska-Różewska ◽  
...  
2020 ◽  
Vol 13 (11) ◽  
pp. 2371-2380
Author(s):  
Ahmed Kamr ◽  
Ali Arbaga ◽  
Amanallah El-Bahrawy ◽  
Ahmed Elsify ◽  
Hadeer Khaled ◽  
...  

Background and Aim: Staphylococcus pyoderma is a common problem in dogs that need a novel treatment rather than antibiotic therapy. The aim of this study was to investigate the therapeutic efficacy, anti-inflammatory, and antioxidative properties of Aloe vera (Aloe barbadensis) gel ointment on dogs' Staphylococcus pyoderma compared to gentamicin ointment. Materials and Methods: The inhibition zone of A. vera extract 20% and 40% and gentamicin 1% against Staphylococcus aureus was determined on well diffusion agar. Twenty Baladi local breed dogs were used as control negative group before intradermal inoculation with 105 CFU S. aureus. The animals were classified into four equal groups, control positive group without treatment (n=5), treated groups by 20% A. vera gel ointment (n=5), 40% A. vera gel ointment (n=5), and gentamicin ointment 1% (n=5). Topical application of A. vera and gentamicin ointments was carried out twice daily for 2 weeks until complete healing of dogs' pyoderma. Clinical evaluation was recorded. Inflammatory, oxidant, and antioxidant parameters were measured in serum. Results: The inhibition zone of A. vera extracts 20% and 40% was 19 mm and 23 mm, respectively, while gentamicin 1% was 18 mm. The half maximal inhibitory concentration (of A. vera 20% and 40% were 13.70 with R2=0.98. Dogs' pyoderma treated with A. vera gel ointment 20% and 40% were more likely to have low haptoglobin and tumor necrosis factor-α concentrations than gentamicin 1% ([odds ratio [OR]=4.6; 95% confidence interval [CI]=1.31-17.40; p<0.05]; [OR=5.2; 95% CI=1.04-22.30; p<0.05]), respectively. Conclusion: It seems evident that A. vera has therapeutic effect, antibacterial, and anti-inflammatory effects against dogs' staphylococcal pyoderma than gentamicin that would support its further use rather than antibiotics in one health arena.


Author(s):  
Farha Fatma ◽  
Anil Kumar

Aloe vera is one of the oldest medicinal plant ever known, commonly known as Ghrit Kumari. It is well known for its therapeutic potential. Some of its beneficial effects include anticancer, hypoglycemic, antifungal, anti-inflammatory, burn healing properties. Phytochemistry of Aloe vera gel has revealed presence of bioactive chemicals. In this review paper, properties of Aloe vera, its composition, its beneficial effects and pharmaceutical uses, its application in foods and cosmetics etc. have been summarized.


2016 ◽  
Vol 80 (7) ◽  
pp. 1416-1424 ◽  
Author(s):  
Marie Saito ◽  
Miyuki Tanaka ◽  
Eriko Misawa ◽  
Ruiquing Yao ◽  
Kazumi Nabeshima ◽  
...  

2014 ◽  
Vol 32 (4) ◽  
pp. 327-340 ◽  
Author(s):  
◽  
Nicole M. Kolacz ◽  
Mark T. Jaroch ◽  
Monica L. Bear ◽  
Rosanna F. Hess

Purpose: The purposes of this pilot study were to measure pain associated with dressing changes, assess the presence of infection, and document healing times of burn-injured Amish in central Ohio using an herbal therapy consisting of Burns and Wounds™ ointment (B&W) and burdock ( Arctium ssp.) leaves. B&W contains honey, lanolin, olive oil, wheat germ oil, marshmallow root, Aloe vera gel, wormwood, comfrey root, white oak bark, lobelia inflata, vegetable glycerin, bees wax, and myrrh. Design: A prospective, case series design guided the study within a community-based participatory research framework. Methods: Amish burn dressers provided burn care. Registered nurses monitored each case and documented findings. Pain scores were noted and burns were inspected for infection during dressing changes; healing times were measured from day of burn to complete closure of the skin. All cases were photographed. Results: Between October 2011 and May 2013, five Amish were enrolled. All had first- and second-degree burns. B&W/burdock leaf dressing changes caused minimal or no pain; none of the burns became infected, and healing times averaged less than 14 days. Conclusion and Implications: The use of this herbal remedy appears to be an acceptable alternative to conventional burn care for these types of burns. The trauma of dressing changes was virtually nonexistent. Nurses working in communities with Amish residents should be aware of this herbal-based method of burn care and monitor its use when feasible.


2014 ◽  
Vol 17 (1) ◽  
pp. 131-136
Author(s):  
P. Skopiński ◽  
S. Lewicki ◽  
B.J. Bałan ◽  
J. Kocik ◽  
R. Zdanowski ◽  
...  

AbstractLymphocyte-induced angiogenesis test (LIA) is a model of local graft-versus-host (GVH) reaction, marker of the earliest events resulting from activation of donor lymphocytes after contact with host semi-allogeneic histocompatibility antigens. The effect of in vivo oral administration of Aloe vera gel for 21 days to maternal strain (Balb/c) donor mice on the ability of their splenic lymphocytes to induce cutaneous angiogenesis (LIA test) in F1 Balb/c x C3H recipients, was studied.Results: Neovascular reaction evaluated 72 hours after cells grafting was significantly lower in F1 mice grafted with lymphocytes collected from Aloe- fed donors, than in recipients of lymphocytes collected from respective controls. Conclusions: This observation opens the promise of safe and ethically acceptable possibility of use of Aloe vera gel in human donors in prevention of GVHD in recipients of bone marrow grafts.


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