ANALYSIS OF THE SAFETY LEVEL OF PHARMACOTHERAPY CHRONIC DISEASES OF THE MENTAL GROUP: REGIONAL ASPECT

2021 ◽  
pp. 73-86
Author(s):  
N. V. Ivanova ◽  
V. S. Belov ◽  
T. V. Kuzmina
Keyword(s):  
Chronic Diseases ◽  
Adverse Reactions ◽  
Single Subject ◽  
Type B ◽  
Safety Level ◽  
Regional Aspect ◽  
Pskov Region ◽  
The Russian Federation ◽  
Drug Provision ◽  
Regional Budgets

The article presents the issues of assessing the level of safety of pharmacotherapy of chronic diseases of the mental group in a single subject of the Russian Federation. It was found that in the Pskov region, when subsidized drug provision for mental illness is financed from the Federal and regional budgets, epilepsies and schizophrenia are the most expensive. The frequency analysis of the occurrence of side effects when taking psychotropic drugs and their systematization by type A — predictable and type B — unpredictable reactions were performed. It is established that adverse reactions are most often encountered when using anticonvulsants.

scholarly journals COMPARATIVE ANALYSIS OF INVESTMENT EXPENDITURES IN BUDGETS: REGIONAL ASPECT

2020 ◽  
pp. 166-173
Author(s):  
M. N. Solomko
Keyword(s):  
Russian Federation ◽  
Applied Research ◽  
Capital Investments ◽  
Investment Activity ◽  
Information Base ◽  
Regional Aspect ◽  
Regional Trends ◽  
The Russian Federation ◽  
High Level ◽  
Regional Budgets

The high level of differentiation of the constituent entities of the Russian Federation determines different approaches to the policy of budget investment. The purpose of the paper is to identify common regional trends in the implementation of capital investments at the expense of budget funds, interregional differences and interpret it. In the study, horizontal and vertical analysis of budget investments has been made, the lack of a significant relationship between the level of budgetary security of the constituent entity of the Russian Federation and the scales of its budget investments has been shown. It has been shown that the investment activity of the constituent entities of the Russian Federation is not a determining fac tor, but an important factor of their investment attractiveness. The materials of the article can be used as an information base for further theoretical and applied research on the expenditures of regional budgets in general and the problem of budget investment in particular.

MONITORING OF ADVERSE REACTIONS ON MEDICINES IN CHILDREN IN THE RUSSIAN FEDERATION

2017 ◽  
Vol 96 (3) ◽  
pp. 152-159
Author(s):  
A. R. Titova ◽  
◽  
I. L. Asetskaya ◽  
V. A. Polivanov ◽  
S. K. Zyryanov ◽  
...  
Keyword(s):  
Russian Federation ◽  
Adverse Reactions ◽  
The Russian Federation

Medical and economic analysis of the consequences of expanding the drug supply program for patients with chronic obstructive pulmonary disease in the Russian Federation

2019 ◽  
pp. 53-61
Author(s):  
Andrei Georgievich Maliavin ◽  
Alana Viktorovna Dzanaeva ◽  
Maria Vladimirovna Avxentyeva ◽  
Sergei Lvovich Babak
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Russian Federation ◽  
Chronic Obstructive ◽  
Outpatient Basis ◽  
Basic Drug ◽  
Obstructive Pulmonary Disease ◽  
Basic Therapy ◽  
The Russian Federation ◽  
The Cost ◽  
Drug Provision

Purpose of the study. Healthcare budget impact analysis in the Russian Federation of providing adult patients with chronic obstructive pulmonary disease (COPD) with basic therapy for outpatient treatment. Material and methods. The hypothesis of reducing costs for the treatment of exacerbations of COPD was tested while providing all patients with basic therapy on an outpatient basis. The model calculates the direct medical costs of drug provision and treatment of exacerbations in patients with COPD in the current situation and when all patients with COPD are covered with basic therapy as part of a program of preferential drug provision. The simulation period is 1 year. The analysis does not take into account social losses associated with disability, payment of disability certificates, reduced labor productivity and mortality. Results. The cost of providing all patients with COPD with the recommended basic drug therapy on an outpatient basis is substantially offset by a decrease in the cost of treating exacerbations: drug costs should increase by 14.1 billion rubles compared with the current situation, while the cost of providing medical care to patients with exacerbations is reduced by 9.7 billion rubles. As a result, the difference in direct medical costs, or the necessary additional investments, is 4.4 billion rubles. The price of drugs used for basic therapy has the greatest impact on the size of the required additional investments. Conclusion. Providing all patients with COPD with the recommended basic drug therapy on an outpatient basis, we can expect a decrease in the number of moderate exacerbations per year by 14.7% and severe exacerbations by 31.2%. Taking into account not only medical, but also socio-economic costs can not only offset additional investments, but also demonstrate significant savings. When implementing a pilot project of preferential drug provision for patients with COPD in a specific region of the Russian Federation, it is possible to reduce the cost of purchasing medicines when forming a municipal order.

Spatial Development of Innovation Systems in Russia

2014 ◽  
Vol 9 (4) ◽  
pp. 289-304 ◽  
Author(s):  
Lidija Sergevna Arkhipova
Keyword(s):  
Economic Development ◽  
Russian Federation ◽  
Chemical Industry ◽  
Innovation System ◽  
Machine Building ◽  
Competitive Advantages ◽  
Regional Aspect ◽  
Level Of Economic Development ◽  
The Russian Federation ◽  
Effective Development

While the development of the country's national innovation system as a whole is very important and should be prioritized, its regional aspect is even more important. The specifics of the Russian Federation's transition to an innovation-based economy is in that that, at the present time, prioritized is the need to ensure the effective development of those economy sectors that underlie the country's specialization and may provide regional and national competitive advantages. To such sectors belong the chemical industry, machine-building and power energetics. We would like to note that initial innovation awareness indicators in the regions are comparable and do not differ greatly but the growth of activity can be observed only in some of the regions. The problem of large differentiation among the constituent entities of the Russian Federation by their level of economic development remains important and has to be dealt with. 

Issues of co-financing of drug provision for the population: international and Russian practice

2020 ◽  
pp. 49-56
Author(s):  
Vasiliy Ryazhenov ◽  
Victoriya Andreyeva ◽  
Elena Zakharochkina
Keyword(s):  
Health Care ◽  
Life Expectancy ◽  
Health System ◽  
Health Care System ◽  
Russian Federation ◽  
High Quality ◽  
Russian President ◽  
The Russian Federation ◽  
Vladimir Putin ◽  
Drug Provision

Russian President Vladimir Putin defined increase in life expectancy from 72.7 to 78 years by 2024 as a national aim in the Decree № 204 of May 7, 2018. Achievement of this aim depends on drug provision system among other factors. Strategy of drug provision for the population of the Russian Federation for the period until 2025 sets the goal of increasing availability of high quality, effective and safe medicines to meet needs of the population and the health system based on the formation of a rational and balanced system of drug provision for the population of the country with available resources. The health care system should expand the possibilities of using modern and effective mechanisms to ensure the financing of drug provision for the population.

PROBLEMS OF THE FORMATION OF REVENUES OF REGIONAL BUDGETS IN THE RUSSIAN FEDERATION

2020 ◽  
Vol 2 (8) ◽  
pp. 83-87
Author(s):  
B. Kh. ALIYEV ◽  
Keyword(s):  
Russian Federation ◽  
Present Stage ◽  
Budget Planning ◽  
Budgetary Policy ◽  
Stage Of Development ◽  
The Russian Federation ◽  
The Republic ◽  
Regional Authorities ◽  
Regional Budgets

In the Russian Federation, the problem of budget planning becomes especially relevant when the pace of economic development slows down. The article examines the features of the formation of regional budgets, using the example of the budget of the Republic of Dagestan. The analysis of incomes to the budget is carried out. The role of regional taxes in the formation of budget revenues of the Republic of Dagestan is revealed. According to the results of the study, it can be concluded that the budgetary policy of the regions at the present stage of development of the Russian economies does not contribute to a further increase in the rates of economic growth. The article offers recommendations for improving the regional budgetary policy of the Russian Federation and increasing the responsibility of regional authorities.

Safety and Immunogenicity of a Combined Diphtheria, Tetanus, Pertussis and Haemophilus influenzae Type b Vaccine in Young Infants

PEDIATRICS ◽  
1993 ◽  
Vol 92 (6) ◽  
pp. 827-832
Author(s):  
Peter R. Paradiso ◽  
Deborah A. Hogerman ◽  
Dace Viceps Madore ◽  
Harry Keyserling ◽  
James King ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Adverse Reactions ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Young Infants ◽  
Tetravalent Vaccine ◽  
Combined Vaccine ◽  
To Receive ◽  
Number Of Injections

Objective. To study the safety and immunogenicity of a combined diphtheria-tetanus-pertussis (DTP)-Haemophilus influenzae type b (HbOC) vaccine (TETRAMUNE) in infants as young as 2 months of age as compared to separate administration of DTP and HbOC. Methods. Two-month-old infants were randomized to receive three doses 2 months apart of either DTP-HbOC as a single 0.5-mL injection or to receive 0.5 mL of DTP and HbOC concurrently in separate legs. Local and systemic adverse reactions were monitored within 72 hours of each immunization, and immunogenicity of each of the four vaccine components was measured. Results. The incidence of both local and systemic adverse events following the tetravalent vaccine was similar to the incidence following separate vaccine administration. After three doses of vaccine, the response to each of the vaccine components was higher in the combined vaccine when compared to separate administration. In the case of the Haemophilus influenzae type b component, this enhancement was also seen after two doses. The response to the combined vaccine was consistent among the three lots tested as was the enhancement over separate administration. Conclusions. The DTP-HbOC vaccine was safe and immunogenic in young infants and was generally more immunogenic than separate vaccination with DTP and HbOC. The use of such a combined vaccine reduces the number of injections given to young infants by half and is an important step toward improving vaccine delivery.

Moxalactam Treatment of Serious Infections Primarily Due to Haemophilus influenzae Type b in Children

PEDIATRICS ◽  
1983 ◽  
Vol 71 (2) ◽  
pp. 187-191
Author(s):  
Sheldon L. Kaplan ◽  
Edward O. Mason ◽  
Sally J. Kvernland ◽  
Elaine M. Loiselle ◽  
Ralph D. Feigin
Keyword(s):  
Haemophilus Influenzae ◽  
Adverse Reactions ◽  
Etiologic Agent ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Cns Infections ◽  
Serious Infections ◽  
Resistant Strains ◽  
Transient Elevation

Thirty-eight children completed therapy with moxalactam for a variety of non-CNS infections. Haemophilus influenzae type b (seven ampicillin-resistant strains) was the etiologic agent for 32 children. Doses of moxalactam ranged from 113 to 200 mg/kg/d in three or four divided doses administered parenterally. All children with infections due to H influenzae type b had excellent responses to moxalactam therapy. Children treated for infections due to other agents also responded satisfactorily to moxalactam therapy. Moxalactam concentrations in joint and pleural fluids greatly exceeded the minimal bactericidal concentrations of moxalactam for H influenzae type b. Adverse reactions included neutropenia, eosinophilia, thrombocytosis, and transient elevation of transaminase levels. Moxalactam administered parenterally, at a dose of 113 to 150 mg/kg/d in three or four divided doses is effective therapy for serious infections in children due to H influenzae type b and selected other organisms.

ASSESSMENT OF THE BUDGETARY POLICY IN THE FIELD OF EQUALIZING BUDGETARY PROVISION IN RUSSIA

2021 ◽  
Vol 2 (3) ◽  
pp. 75-82
Author(s):  
O. R. TEGETAEVA ◽  
◽  
L. V. BASIEVA ◽  
A. A. BALIKOEVA ◽  
◽  
...  
Keyword(s):  
Economic Growth ◽  
Russian Federation ◽  
Financial Resources ◽  
Budgetary Policy ◽  
Theoretical Approaches ◽  
The Russian Federation ◽  
Regional Budgets ◽  
The Impact

The article highlights theoretical approaches to defining the concepts of budgetary provision of the budgets of the constituent entities of the Russian Federation. In this regard, an analysis of changes in the levels of subsidization of regional budgets is carried out, taking into account changes in the methods of distributing subsidies to regions, an assessment is made of the impact of changes in the management of public financial resources on the economic growth of regions.

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