Modelling the Soufrière Hills Volcano; Investigating the Montserrat magmatic system with co-analysis of EDM and GPS data

2021 ◽  
Author(s):  
Alexander Johnson ◽  
James Hickey ◽  
Karen Pascal ◽  
Ben Williamson ◽  
Racquel Syers
Keyword(s):  
Finite Element ◽  
Ground Deformation ◽  
Monitoring Network ◽  
Line Length ◽  
Gps Data ◽  
Magmatic System ◽  
Source Pressure ◽  
Wide Range ◽  
First Time ◽  
Electronic Distance Measurement

<p>Ground deformation offers vital insight into the activity of volcanoes, as well as the characteristics of the magmatic systems that feed them. The extended eruption of the Soufrière Hills Volcano (SHV) has allowed for the development of a comprehensive multi-disciplinary monitoring network, which has aided extensive research into the magmatic system underlying the volcano. The modern network comprises GPS, strainmeters, and cheaper Electronic Distance Measurement (EDM). However, the island’s EDM network has to date only being used for monitoring the SHV. Here, for the first time, we co-analyse the EDM dataset from 2010-19 with the GPS data from the same period. This study aims to delineate the modern magmatic system conditions by building 3D Finite Element Models, as well as assessing the best use of EDM data in modelling the SHV.</p><p>The island-wide deformation recorded over the past decade at the GPS network is broadly radial relative to the SHV dome, with a decreasing deformation rate. The EDM data shows line lengthening on the west and east flanks of the volcano, but minor line length shortening on the northern flank. We utilise Finite Element Modelling to model the SHV magmatic system as a single elongated prolate with 3D topography incorporated. We systematically test a wide range of parameters to explore how both EDM and GPS record perturbations to the magmatic system. Our preliminary results show that variations of certain parameters to the deeper magmatic system have an impact on both EDM and GPS timeseries, while some parameters (e.g., source pressure, source depth, and source location) have a more significant effect on EDM measurements than others (e.g., source shape).</p>

Safety assessment of biological raw materials in the system of medicines quality assurance

2020 ◽  
pp. 63-72
Author(s):  
Yu. Olefir ◽  
E. Sakanyan ◽  
I. Osipova ◽  
V. Dobrynin ◽  
M. Smirnova ◽  
...  
Keyword(s):  
Raw Materials ◽  
State Level ◽  
The State ◽  
Spongiform Encephalopathy ◽  
Safety Standards ◽  
Wide Range ◽  
The Russian Federation ◽  
Key Aspects ◽  
First Time ◽  
Medicines Quality

The entry of a wide range of biotechnological products into the pharmaceutical market calls for rein-forcement of the quality, efficacy and safety standards at the state level. The following general monographs have been elaborated for the first time to be included into the State Pharmacopoeia of the Russian Federation, XIV edition: "Viral safety" and "Reduction of the risk of transmitting animal spongiform encephalopathy via medicinal products". These general monographs were elaborated taking into account the requirements of foreign pharmacopoeias and the WHO recommendations. The present paper summarises the key aspects of the monographs.

Innovation in Byzantine Medicine

2020 ◽  
Author(s):  
Petros Bouras-Vallianatos
Keyword(s):  
Human Physiology ◽  
Medical Literature ◽  
Cultural Exchange ◽  
Significant Degree ◽  
Medieval Medicine ◽  
Medieval Latin ◽  
Main Thesis ◽  
Wide Range ◽  
Comprehensive Examination ◽  
First Time

Byzantine medicine is still a little-known and misrepresented field not only in the wider arena of debates on medieval medicine but also among Byzantinists. Byzantine medical literature is often viewed as ‘stagnant’ and mainly preserving ancient ideas; and our knowledge of it continues to be based to a great extent on the comments of earlier authorities, which are often repeated uncritically. This book presents the first comprehensive examination of the medical corpus of, arguably, the most important late Byzantine physician John Zacharias Aktouarios (c.1275–c.1330). The main thesis is that John’s medical works show an astonishing degree of openness to knowledge from outside Byzantium combined with a significant degree of originality, in particular, in the fields of uroscopy, pharmacology, and human physiology. The analysis of John’s edited (On Urines and On Psychic Pneuma) and unedited (Medical Epitome) works is supported for the first time by the consultation of a large number of manuscripts. The study is also informed by evidence from a wide range of medical sources, including previously unpublished ones, and texts from other genres, such as epistolography and merchants’ accounts. The contextualization of John’s works sheds new light on the development of Byzantine medical thought and practice, and enhances our understanding of the late Byzantine social and intellectual landscape. Finally, John’s medical observations are also examined in the light of examples from the medieval Latin and Islamic worlds, placing his medical theories in the wider Mediterranean milieu and highlighting the cultural exchange between Byzantium and its neighbours.

Rebels, Believers, Survivors

2020 ◽  
Author(s):  
Noel Malcolm
Keyword(s):  
Catholic Church ◽  
Religious Conversion ◽  
Late Nineteenth Century ◽  
Napoleonic Wars ◽  
Conversion To Islam ◽  
Wide Range ◽  
History Of ◽  
External Powers ◽  
First Time ◽  
Modern Myth

This book of essays covers a wide range of topics in the history of Albania and Kosovo. Many of the essays illuminate connections between the Albanian lands and external powers and interests, whether political, military, diplomatic or religious. Such topics include the Habsburg invasion of Kosovo in 1689, the manoeuvrings of Britain and France towards the Albanian lands during the Napoleonic Wars, the British interest in those lands in the late nineteenth century, and the Balkan War of 1912. On the religious side, essays examine ‘crypto-Christianity’ in Kosovo during the Ottoman period, the stories of conversion to Islam revealed by Inquisition records, the first theological treatise written in Albanian (1685), and the work of the ‘Apostolic Delegate’ who reformed the Catholic Church in early twentieth-century Albania. Some essays bring to life ordinary individuals hitherto unknown to history: women hauled before the Inquisition, for example, or the author of the first Albanian autobiography. The longest essay, on Ali Pasha, tells for the first time the full story of the role he played in the international politics of the Napoleonic Wars. Some of these studies have been printed before (several in hard-to-find publications, and one only in Albanian), but the greater part of this book appears here for the first time. This is not only a contribution to Albanian and Balkan history it also engages with many broader issues, including religious conversion, methods of enslavement within the Ottoman Empire, and the nature of modern myth-making about national identity.

Recycling and Reuse in the Roman Economy

2020 ◽  
Keyword(s):  
Building Materials ◽  
Computational Modelling ◽  
Late Antique ◽  
Roman Economy ◽  
Wide Range ◽  
The Status ◽  
Recent Developments ◽  
Methodological Approaches ◽  
First Time ◽  
Site Types

The recycling and reuse of materials and objects were extensive in the past, but have rarely been embedded into models of the economy; even more rarely has any attempt been made to assess the scale of these practices. Recent developments, including the use of large datasets, computational modelling, and high-resolution analytical chemistry, are increasingly offering the means to reconstruct recycling and reuse, and even to approach the thorny matter of quantification. Growing scholarly interest in the topic has also led to an increasing recognition of these practices from those employing more traditional methodological approaches, which are sometimes coupled with innovative archaeological theory. Thanks to these efforts, it has been possible for the first time in this volume to draw together archaeological case studies on the recycling and reuse of a wide range of materials, from papyri and textiles, to amphorae, metals and glass, building materials and statuary. Recycling and reuse occur at a range of site types, and often in contexts which cross-cut material categories, or move from one object category to another. The volume focuses principally on the Roman Imperial and late antique world, over a broad geographical span ranging from Britain to North Africa and the East Mediterranean. Last, but not least, the volume is unique in focusing upon these activities as a part of the status quo, and not just as a response to crisis.

scholarly journals A Virtual Telescope for the Open University Science Foundation Course

1998 ◽  
Vol 162 ◽  
pp. 100-105
Author(s):  
Andrew J. Norton ◽  
Mark H. Jones
Keyword(s):  
Social Science ◽  
Open University ◽  
Distance Teaching ◽  
The Arts ◽  
Wide Range ◽  
University Science ◽  
First Time ◽  
Degree Level ◽  
Selection Of

The Open University is the UK's foremost distance teaching university. For over twenty five years we have been presenting courses to students spanning a wide range of degree level and vocational subjects. Since we have no pre-requisites for entry, a major component of our course profile is a selection of foundation courses comprising one each in the Arts, Social Science, Mathematics, Technology and Science faculties. The Science Faculty's foundation course is currently undergoing a substantial revision. The new course, entitled “S103: Discovering Science”, will be presented to students for the first time in 1998.

scholarly journals Autophagy Deficiency by Atg4B Loss Leads to Metabolomic Alterations in Mice

Metabolites ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 481
Author(s):  
Gemma G. Martínez-García ◽  
Raúl F. Pérez ◽  
Álvaro F. Fernández ◽  
Sylvere Durand ◽  
Guido Kroemer ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Amino Acids ◽  
Mammalian Cells ◽  
Tissue Homeostasis ◽  
In Vivo Studies ◽  
Protective Mechanism ◽  
Cardiac Damage ◽  
Wide Range ◽  
First Time

Autophagy is an essential protective mechanism that allows mammalian cells to cope with a variety of stressors and contributes to maintaining cellular and tissue homeostasis. Due to these crucial roles and also to the fact that autophagy malfunction has been described in a wide range of pathologies, an increasing number of in vivo studies involving animal models targeting autophagy genes have been developed. In mammals, total autophagy inactivation is lethal, and constitutive knockout models lacking effectors of this route are not viable, which has hindered so far the analysis of the consequences of a systemic autophagy decline. Here, we take advantage of atg4b−/− mice, an autophagy-deficient model with only partial disruption of the process, to assess the effects of systemic reduction of autophagy on the metabolome. We describe for the first time the metabolic footprint of systemic autophagy decline, showing that impaired autophagy results in highly tissue-dependent alterations that are more accentuated in the skeletal muscle and plasma. These changes, which include changes in the levels of amino-acids, lipids, or nucleosides, sometimes resemble those that are frequently described in conditions like aging, obesity, or cardiac damage. We also discuss different hypotheses on how impaired autophagy may affect the metabolism of several tissues in mammals.

scholarly journals Anatomy of a Paroxysmal Lava Fountain at Etna Volcano: The Case of the 12 March 2021, Episode

2021 ◽  
Vol 13 (15) ◽  
pp. 3052
Author(s):  
Sonia Calvari ◽  
Alessandro Bonaccorso ◽  
Gaetana Ganci
Keyword(s):  
Lava Flow ◽  
Ground Deformation ◽  
Monitoring Network ◽  
Lava Flows ◽  
Etna Volcano ◽  
Lava Fountain ◽  
Eruptive Episode ◽  
Lava Fountains ◽  
Borehole Strainmeter ◽  
Ash Plume

On 13 December 2020, Etna volcano entered a new eruptive phase, giving rise to a number of paroxysmal episodes involving increased Strombolian activity from the summit craters, lava fountains feeding several-km high eruptive columns and ash plumes, as well as lava flows. As of 2 August 2021, 57 such episodes have occurred in 2021, all of them from the New Southeast Crater (NSEC). Each paroxysmal episode lasted a few hours and was sometimes preceded (but more often followed) by lava flow output from the crater rim lasting a few hours. In this paper, we use remote sensing data from the ground and satellite, integrated with ground deformation data recorded by a high precision borehole strainmeter to characterize the 12 March 2021 eruptive episode, which was one of the most powerful (and best recorded) among that occurred since 13 December 2020. We describe the formation and growth of the lava fountains, and the way they feed the eruptive column and the ash plume, using data gathered from the INGV visible and thermal camera monitoring network, compared with satellite images. We show the growth of the lava flow field associated with the explosive phase obtained from a fixed thermal monitoring camera. We estimate the erupted volume of pyroclasts from the heights of the lava fountains measured by the cameras, and the erupted lava flow volume from the satellite-derived radiant heat flux. We compare all erupted volumes (pyroclasts plus lava flows) with the total erupted volume inferred from the volcano deflation recorded by the borehole strainmeter, obtaining a total erupted volume of ~3 × 106 m3 of magma constrained by the strainmeter. This volume comprises ~1.6 × 106 m3 of pyroclasts erupted during the lava fountain and 2.4 × 106 m3 of lava flow, with ~30% of the erupted pyroclasts being remobilized as rootless lava to feed the lava flows. The episode lasted 130 min and resulted in an eruption rate of ~385 m3 s−1 and caused the formation of an ash plume rising from the margins of the lava fountain that rose up to 12.6 km a.s.l. in ~1 h. The maximum elevation of the ash plume was well constrained by an empirical formula that can be used for prompt hazard assessment.

Nonlinear dynamic behaviour of guy cables in turbulent winds

2001 ◽  
Vol 28 (1) ◽  
pp. 98-110 ◽  
Author(s):  
Bruce F Sparling ◽  
Alan G Davenport
Keyword(s):  
Finite Element ◽  
Dynamic Behaviour ◽  
Aerodynamic Drag ◽  
Numerical Study ◽  
Horizontal Displacement ◽  
Wind Loading ◽  
Second Phase ◽  
Nonlinear Coupling ◽  
Wide Range ◽  
Cable Vibrations

Large amplitude cable vibrations are difficult to predict using linear theory due to the presence of sag in the suspended profile. A numerical study was therefore undertaken to investigate the dynamic behaviour of inclined cables excited by imposed displacements. To model the nonlinear nature of cable response, a time domain finite element approach was adopted using nonlinear catenary cable elements. Two types of horizontal displacement patterns were enforced at the upper end of the guy. In the first phase of the study, harmonic displacement histories with a wide range of forcing frequencies were considered. In the second phase, random enforced displacements were used to simulate the motion of a guyed mast in gusty winds. The influence of aerodynamic drag and damping forces was investigated by performing analyses under still air, steady wind, and turbulent wind conditions. It was found that nonlinear coupling of related harmonic response components was significant at certain critical frequencies, particular when the excitation was harmonic and acted in the plane of the guy. Positive aerodynamic damping was shown to effectively suppress resonant and nonlinear coupling response.Key words: cables, structural dynamics, wind loading, finite element method, nonlinear analysis, guyed towers.

Local Hydrostatic Pressure Test for Cylindrical Vessels

2016 ◽  
Vol 139 (1) ◽  
Author(s):  
H. Al-Gahtani ◽  
A. Khathlan ◽  
M. Sunar ◽  
M. Naffa'a
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Hydrostatic Pressure ◽  
Cylindrical Vessel ◽  
Geometrical Parameters ◽  
The Finite Element Method ◽  
Wide Range ◽  
Pressure Test ◽  
Local Test ◽  
Alternative Test

The juncture of a small cylindrical nozzle to a large cylindrical vessel is very common in the pressure vessel industry. Upon fabrication, it is required that the whole structure is subjected to pressure testing. The test can be expensive as it necessitates pressurizing the whole structure typically having a large volume. Hence, it is proposed to make a “local test,” which is considerably simpler as it involves capping the small nozzle and testing only a relatively small portion of the structure. This paper investigates the accuracy and reliability of such an alternative test, using the finite-element method. Two different finite-element types are used in the study, specifically a shell-based element and a solid-based element. The verification of the finite-element results for two different cases shows that the models used in the study are valid. It also proves that the two element types yield very similar stress results. In addition, the study includes a numerical investigation of more than 40 different nozzle-to-vessel junctures with a wide range of parameters for the nozzle and vessel. The results indicate that the use of cylindrical caps that are slightly larger than the nozzle is not recommended as it produces stresses that are significantly different from those for the original required pressure test. As such, the study provides an estimate of the smallest size of the cap that may be used in the local test to generate stresses that agree with the full test. For most practical geometries, it is shown that the size of the cap needs to be at least 2–30 times larger than that of the nozzle, depending on the geometrical parameters of the juncture.

NOVEL COUPLING CONSTRAINT TECHNIQUE FOR EXPLICIT FINITE ELEMENT ANALYSIS

2004 ◽  
Vol 01 (02) ◽  
pp. 309-328
Author(s):  
R. J. HO ◽  
S. A. MEGUID ◽  
R. G. SAUVÉ
Keyword(s):  
Finite Element ◽  
Current Method ◽  
Explicit Integration ◽  
Rotation Tensor ◽  
Element Analysis ◽  
Explicit Finite Element ◽  
Explicit Finite Element Analysis ◽  
Wide Range ◽  
Large Rotations ◽  
Generalized Constraint

This paper presents a unified novel technique for enforcing nonlinear beam-to-shell, beam-to-solid, and shell-to-solid constraints in explicit finite element formulations. The limitations of classical multi-point constraint approaches are examined at length, particularly in the context of explicit solution schemes. Novel formulation of a generalized constraint method that ensures proper element coupling is then presented, and its computer implementation in explicit integration algorithms is discussed. Crucial in this regard is the accurate and efficient representation of finite rotations, accomplished using an incremental rotation tensor. The results of some illustrative test cases show the accuracy and robustness of the newly developed algorithm for a wide range of deformation, including that in which large rotations are encountered. When compared to existing works, the salient features of the current method are in evidence.

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