Determinants of Iron Deficiency Anemia Among Pregnant Females Visiting Tertiary Care Hospitals, Lahore

Author(s):  
Anam Junaid ◽  
Iqra Masood ◽  
Ms Khansa ◽  
Shahnai Basharat ◽  
Morad Yaser Al Mostafa

Iron deficiency anemia refers to the anemia caused by insufficient iron stores within the body. The main cause of anemia in obstetrics is iron deficiency, which has a worldwide prevalence estimated between 20%–80% and constitutes mainly female population.  Objective: To find out the determinants of iron deficiency anemia amongst pregnant women visiting Tertiary Care Hospitals, Lahore. Methods: A cross-sectional study was conducted at Sir Ganga Ram Hospital, Lahore. A sample of 245 pregnant female patients was selected through non-probability convenient sampling technique. Data were collected with the pre-tested questionnaires. SPSS version 21.0 was used for data analysis. Results: Amongst social determinants, socioeconomic status had a signifcant effect on iron defciency anemia; as 82% women belonged to low socioeconomic status. Among dietary determinants, less consumption of red meat was a major factor affecting IDA as 95% women were not consuming red meat more than two times a day thus contributing to overall iron defciency. Amongst clinical factors, lack of thorough clinical checkup before conception was a major factor as 79% women did not have regular clinical checkup before pregnancy. Conclusions: Major determinants linked with IDA were dietary habits and practices such as preferring vegetables over meat, less overall consumption of red meat and excessive consumption of tea and coffee. Other determinants affecting IDA include low socioeconomic status, little or no gap between pregnancies and lack of knowledge and education concerning dietary practices during pregnancy.   

2017 ◽  
Vol 56 (5) ◽  
pp. 277 ◽  
Author(s):  
Henny Adriani Puspitasari ◽  
Endang Windiastuti ◽  
Aryono Hendarto

Background Preterm infants are vulnerable to iron deficiency (ID) due to lack of maternal iron stores, repeated phlebotomy, and the body’s increased demand for iron during growth. The risk of ID increases at 2 months of age, when hemoglobin (Hb) levels start to decrease. Adequacy of body iron level is assessed by ferritin, serum iron (SI), transferrin saturation (Tfsat), total iron-binding capacity (TIBC), and Hb measurements.Objective To describe iron profiles in preterm infants at 2 months of chronological age (CA).Methods This cross-sectional study was conducted in 2-month-old infants, born at 32-36 weeks of gestational age, and who visited the Growth and Development Clinics at Cipto Mangunkusumo, Fatmawati, or Budi Kemuliaan Hospitals. Parental interviews and medical record reviews were done during the clinic visits. Complete blood count, blood smear, SI, TIBC, Tfsat, and ferritin level tests were performed.Results Eighty-three subjects were enrolled in this study. Most subjects were male (51%) and born to mothers >20 years of age (93%). Subjects’ birth weights ranged from 1,180 g to 2,550 g. The prevalence of iron deficiency anemia (IDA) was 6% and that of ID was 10%. The lowest Hb level found in IDA infants was 6.8 g/dL, while the lowest ferritin level was 8.6 ng/mL. Median values for the other tests were as follows: SI 48 µg/dL, TIBC 329µg/dL, and Tfsat 17%. Subjects with IDA were all male (5/5), mostly achieved more than twice their birth weight (4/5), were non-iron supplemented (3/5), born to mothers with low educational background (3/5), and of low socioeconomic status (3/5).Conclusion The prevalence of IDA is 6% and that of ID is 10%. Most subjects with ID and IDA have low SI, high TIBC, low Tfsat, and low ferritin level. Most of the all-male IDA subjects weigh more than twice their birth weight, are non-iron supplemented, and born to mothers with low educational background and low socioeconomic status.


2018 ◽  
Vol 5 (4) ◽  
pp. 1631
Author(s):  
Inderpreet Santokh ◽  
Bablu Kumar Gaur ◽  
Raghvendra Narayan ◽  
Baljeet Maini ◽  
A. K. Bharadwaj

Background: Iron deficiency anemia is the most common nutritional deficiency disorder in the world. The present study was conducted to know the prevalence and severity of iron deficiency anemia among of 6 months to 60 months old children. A large proportion of iron deficiency is preventable with appropriate and timely intervention.Methods: This cross-sectional study was done on 100 children clinically suggestive of anemia with hemoglobin level less than 11gm/dl admitted in pediatrics ward of tertiary care hospital. 5 ml of blood sample was taken and complete hemogram, peripheral blood film and serum ferritin estimation was done. Case were studied in reference to history, age, clinical examination, hemoglobin level and confirmation of iron deficiency anemia was done by serum ferritin levels.Results: The prevalence of iron deficiency anemia in present study was 56%. It was most prevalent in the age group of 6 to 24 months. Exclusively breastfed children showed higher prevalence of iron deficiency anemia in present study, however no statistical correlation was found. Low Serum ferritin levels have statistically significant result with socioeconomic status, with as many as 69.4% suffering from iron deficiency anemia belonging to low socioeconomic status.Conclusions: Prevalence of iron deficiency anemia remains alarmingly high and major health problem in our country. All anemia are not iron deficiency anemia. Low socioeconomic status is a huge hurdle in child health and greatly influences prevalence of iron deficiency anemia. Serum ferritin is a most sensitive marker of iron deficiency anemia, helps diagnose it early in its course, which can be missed on clinical or routine blood investigations.


2020 ◽  
Vol 6 (2) ◽  
pp. 3-9
Author(s):  
Mazhar Khan ◽  
Irum Naz ◽  
Farida Shirazi ◽  
Rifayat Ullah Afridi ◽  
Aneela Ambreen ◽  
...  

ABSTRACT: OBJECTIVES: The purpose of this study was to know about the risk factors of malnutrition and the incidence of risk factors among known cases of malnutrition admitted in tertiary care hospitals of Peshawar. METHODOLOGY: A descriptive cross-sectional study was done. Study was conducted in tertiary care hospitals of Peshawar from March 2019 to July 2019. Study included 100 patients of protein calorie malnutrition less than five years of age. Internationally recognized Gomez classification was used to label patient as malnourished. Risk factors of primary malnutrition including socioeconomic status, ignorance of weaning, poverty, lack of immunization and primary care, maternal illiteracy and risk factors of secondary malnutrition including infections, congenital diseases, malabsorptive disorders and metabolic disorders were assessed. Data was collected through a questionnaire. Tables and graphs were used to determine the frequency of risk factors for protein calorie malnutrition. RESULTS: Among 100 patients of PCM 59 were male and 41 were females. After assessment of both genders, risk factors that show close association with protein calorie malnutrition were low socioeconomic status, maternal illiteracy, lack of family planning, poor weaning and repeated infections. Among these risk factors the most frequently observed risk factors for protein calorie malnutrition were low socioeconomic status and repeated infections. CONCLUSION: Low socioeconomic condition and repeated infections are the leading cause of protein calorie malnutrition. KEYWORDS: Malnutrition, Gomez Classification, Frequency, Risk Factors


2018 ◽  
Vol 7 (1) ◽  
pp. 1-5
Author(s):  
Rinku Joshi ◽  
Dhan Bahadur Shrestha ◽  
Drishti RL Shah ◽  
Sitaram Khadka

Background and aim: Iron deficiency refers to the reduction of iron stores that precedes overt iron deficiency anemia. Iron deficiency anemia (IDA) is the commonest nutritional deficiency around the globe. Though etiology of IDA is multifaceted, and results from the iron demands which is not met by iron absorption in the body, regardless of the reason. This study was aimed to observe the several hematologic parameters among IDA cases presented to a tertiary level referral hospital of Nepal army.Methods: This prospective hospital based study was conducted among cases of iron deficiency anemia presented to a hematology clinic for six-month duration. With the help of semi-structured questionnaire demographic variables, presenting complaints, baseline laboratory parameters, iron profile and etiology of iron deficiency anemia were recorded. The collected data were entered in SPSS version 22 and analyzed.Results: In the six-month study period, there were 175 IDA cases who presented to hematology clinic. IDA was more common in females accounting 78% of 175 cases while rest were male. Mean value of parameters of iron profile were all significantly lower than normal range except TIBC which was significantly raised clinching the diagnosis of IDA. Weakness was the commonest mode of presentation (83, 47.4%). Poor intake was the main culprit of IDA (88, 50.3%). Most of the cases (82, 46.9%) belonged to moderate anemia group. Severity of anemia was associated with platelet count and total leucocyte count (p<0.05) while it was not associated with iron profile values (p>0.05).Conclusion: In adult group, IDA is more common in women and non-specific symptoms like weakness is the commonest mode of presentation. Poor dietary intake is the main cause of IDA in our context. Among IDA cases, most of them belonged to moderate anemia.


Author(s):  
Kirtan Krishna ◽  
Achint Krishna ◽  
Divya Teja G. N.

Background: Postpartum iron deficiency anemia is common in India as a consequence of postpartum hemorrhage.  Recent studies have evaluated the use of parenteral iron as a better tolerated treatment modality. Compared with oral iron supplements, parenteral iron is associated with a rapid rise in serum ferritin and hemoglobin and improved maternal fatigue scores in the postpartum period.  Parenteral iron may be considered for the treatment of postpartum anemia. The objective of the study was to evaluate the efficacy, safety, and tolerability of intravenous ferric carboxymaltose, in women with postpartum anemia.Methods: A clinical observational study was undertaken in a tertiary care hospital,  50 women within six weeks of delivery with Hb ≥6 gm/dl and ≤10 gm/dl received 1000 mg/week,  over 15 minutes or less, repeated weekly to a calculated replacement dose (maximum 2500 mg) . Hemoglobin and serum ferritin levels were recorded prior to treatment and on day 21 after completion of treatment.Results: Ferric carboxymaltose-treated subjects achieved a hemoglobin greater than 12 gm/dL in a short time period (21 days), achieve a hemoglobin rise of ≥3 gm/dL more quickly, and attain higher serum ferritin levels. It is also associated with better patient compliance, and shorter treatment period. Drug-related adverse events occurred less frequently with ferric carboxymaltose. The only noted disadvantage was that it is more expensive when compared to other iron preperations.Conclusions: Intravenous ferric carboxymaltose was safe and well tolerated with good efficacy and better patient compliance in the treatment of postpartum iron deficiency anemia.


2012 ◽  
Vol 19 (1) ◽  
pp. 77
Author(s):  
Sri Budiarti Wongsohardjono

Background: Iron deficiency anemia is a microcytic anemia caused by chronic blood loss dueto such problems as excessive menstrual flow, gastrointestinal bleeding, gasterektomi or malabsorption that reduces the absorption of Fe. Predisposing factors that lead to the disruption of the ecology of oral candidiasis or oral microbiological changes can be due to malnutrition (iron deficiency, folic acid, vitamin B12) and the very old age. Objective: To report a case of iron deficiency anemia with oral candidiasis and its management. Case Report: A 69-year man in the reference by peer demonstrated swollen gums, mouth pain and difficulty in swallowing. A moth ago he was hospitalized and boarded for a week but no change, his body weight loss was 25kg. paleconjunctiva and face, droliing, looked weak. The body temperature was 370 C; the BP measurement was: 125/80mmHg; with body weight was 50kg; right and left submandibular  lymph nodes become enlarging and soreness palpatiom. Symmetrical face. Right and left lip corners are angular kheilitis, cheek mucosa, palate hyperemia, gingival stipling was disappeared, hyperemia, dorsal surface smooth tongue, hyperemia, depapilasi, OHI: bad; thick saliva, hypersalivation. A lot of dental caries and the remaining roots. Management: Examination of the saliva with KOH solution looked a hyphe. Routine blood tests and profile of fe all within normal limits except RBC was 3,37.106 / uL; HGB: 11.0 g / dl; HCT: 32.2%, Fe 29.00 u g / dl (below normal). Treatment with 3% perhidrol mouthwash, Nyistatin solution 3 x daily. Zegase tablet 2x daily. Paracetamol tablets if necessary. Conclusion sixteen days later the patient recovered.


2021 ◽  
pp. 32-39
Author(s):  
Н.А. САДИЕВА ◽  
А.Э. МАМЕДОВА

В публикации авторы представили теоретический обзор распространения анемии у детей во всем мире, в том числе и в Азербайджане, роли железа в организме, причинах возникновения железодефицитной анемии и его классификации, особенностях проведения ферротерапии у детей, классификации железосодержащих средств применяемых в Азербайджане, протоколах лечения ЖДА у детей во всем мире, в том числе и в Азербайджане. In the publication the authors presented a theoretical review of the spread of anemia in children worldwide, including Azerbaijan, the role of iron in the body, the causes of iron deficiency anemia and its classification, the peculiarities of ferrotherapy in children, the classification of iron-containing agents used in Azerbaijan, the treatment protocols for iron deficiency in children worldwide, including in Azerbaijan.


2012 ◽  
Vol 08 (02) ◽  
pp. 74
Author(s):  
Mark Janis ◽  

Anemia is highly prevalent, affecting approximately 40 % of cancer patients, and results in a significant decrease in health-related quality of life while also being associated with shorter cancer survival times. A recent survey of 15,000 cancer patients in Europe found that 39 % were anemic at the time of enrolment. In addition, anemia is a recognized complication of myelosuppressive chemotherapy, and it has been estimated that, in the US, around 1.3 million cancer patients who are not anemic at the time of diagnosis will develop anemia during the course of their disease. The etiology of anemia in cancer patients is variable and often multifactorial, and may be the result of an absolute or a functional iron deficiency. Cancer produces an enhanced inflammatory state within the body—causing hepcidin levels to increase and erythropoietin production to decrease—and results in a reduction in erythropoiesis due to impaired iron transport. This type of anemia is known as functional iron deficiency, where the body has adequate iron stores but there are problems with mobilization and transport of the iron. Absolute iron deficiency is when both iron stores and iron transport are low. The National Comprehensive Cancer Network (NCCN) treatment guidelines for cancer-related anemia recommend intravenous (IV) iron products alone for iron repletion in cancer patients with absolute iron deficiency, and erythropoiesis-stimulating agents (ESAs) in combination with IV iron in cancer patients (currently undergoing palliative chemotherapy) with functional iron deficiency. Although IV iron has been demonstrated to enhance the hematopoietic response to ESA therapy, the use of supplemental iron has not yet been optimized in oncology. Here we discuss the significance of iron deficiency anemia in cancer patients and the need to implement tools to properly diagnose this condition, and we provide an overview of the management strategies and recommendations for patients with iron deficiency anemia as outlined in the NCCN guidelines.


2007 ◽  
Vol 28 (3) ◽  
pp. 328-336 ◽  
Author(s):  
Prashanth Thankachan ◽  
Sumithra Muthayya ◽  
Thomas Walczyk ◽  
Anura V. Kurpad ◽  
Richard F. Hurrell

Background Anemia and iron deficiency are significant public health problems in India, particularly among women and children. Recent figures suggest that nearly 50% of young Indian women are anemic. Objectives Few studies have comprehensively assessed etiologic factors contributing to anemia and iron deficiency in India. Hence, this study assessed the relative importance of various factors contributing to these problems in young women of low socioeconomic status in Bangalore, India. Methods A random sample of 100 nonpregnant, nonlactating women 18 to 35 years of age, selected from among 511 women living in a poor urban settlement, participated in this study. Data were obtained on demography, socioeconomic status, anthropometry, three-day dietary intake, blood hemoglobin, hemoglobinopathies, serum ferritin, serum C-reactive protein, and stool parasites. Results The prevalence rates of anemia and iron deficiency were 39% and 62%, respectively; 95% of the anemic women were iron deficient. The mean dietary iron intake was 9.5 mg per day, predominantly from the consumption of cereals, pulses, and vegetables (77%). The estimated bioavailability of nonheme iron in this diet was 2.8%. Dietary intakes were suboptimal for several nutrients. Blood hemoglobin was significantly correlated with dietary intake of fat, riboflavin, milk and yogurt, and coffee. Serum ferritin was significantly correlated with intake of niacin, vitamin B12, and selenium. Parasitic infestation was low. Conclusions An inadequate intake of dietary iron, its poor bioavailability, and concurrent inadequate intake of dietary micronutrients appear to be the primary factors responsible for the high prevalence of anemia and iron deficiency in this population.


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