scholarly journals The use of botanical raw materials in hair dyeing

2021 ◽  
Vol 10 (6) ◽  
pp. 263-269
Author(s):  
Natalia Schäfer ◽  
◽  
Radosław Balwierz ◽  
Anna Krzeszewska-Zaręba ◽  
Zbigniew Skotnicki ◽  
...  
Keyword(s):  
Side Effects ◽  
Raw Materials ◽  
Full Range ◽  
Target Color ◽  
Short Term ◽  
Plant Materials ◽  
Natural Hair ◽  
Materials Used

The cosmetic market is rich in products that allow changing the color of hair. There are three options for chemical coloring, depending on the duration of the target color. Among them, there are short-term, semi-permanent, and long-term dyeing. Using synthetic ingredients, it is possible to obtain a full range of colors. Reports of undesirable side effects of chemical dyes on both the scalp and hair structure support a return to natural hair coloration and a development in this direction. The aim of the work was to draw attention to apply botanical raw materials in hair dyeing. The work presents the characteristics of the following plant materials used in hair dyeing: defenseless lawsonia, oxalic hibiscus, rhubarb, elderberry and chamomile.

Antimicrobial Applications of Nanoparticles

2022 ◽  
pp. 269-288
Author(s):  
Ayesha Kanwal ◽  
Zeeshan Ahmad Bhutta ◽  
Ambreen Ashar ◽  
Ashar Mahfooz ◽  
Rizwan Ahmed ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Side Effects ◽  
Antibacterial Agent ◽  
Antibacterial Agents ◽  
The Other ◽  
Drug Resistant ◽  
Short Term ◽  
Human Mortality ◽  
Recent Developments

Human mortality due to drug-resistant infections is becoming more prevalent in our society. Antibiotics are impotent due to abuse and/or misuse, leading to new, more expensive, and more effective medicines and treatments. Therefore, it causes many short-term and long-term side effects in the patient. On the other hand, nanoparticles have exhibited antibacterial activity against various pathogens due to their small size and ability to destroy cells by various mechanisms. Unlike antibiotics for the treatment of patients' diseases and infections, nanomaterials provide an exciting way to limit the growth of microorganisms due to infections in humans. This has led to the development of a number of nanoparticles as active antibacterial agents. Therefore, the authors have carefully reviewed the recent developments in the use of nanomaterials for antibacterial applications and the mechanisms that make them an effective alternate antibacterial agent.

Efficacy and safety of percutaneous administration of dihydrotestosterone in children of different genetic backgrounds with micropenis

2017 ◽  
Vol 30 (12) ◽  
Author(s):  
Dan Xu ◽  
Liangsheng Lu ◽  
Li Xi ◽  
Ruoqian Cheng ◽  
Zhou Pei ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Side Effects ◽  
Low Doses ◽  
Efficacy And Safety ◽  
Short Term ◽  
Term Study ◽  
Long Term Study ◽  
Percutaneous Administration ◽  
Open Prospective Study

AbstractBackground:Exogenous androgen supplement is an optional treatment for micropenis; however, its use in childhood is controversial due to potential side effects.Methods:Twenty-three children (mean age: 4.07±3.4 years) with micropenis of unknown causes harboring the 46,XY karyotype were recruited in an open prospective study. Androgen receptor (Results:Two patients were found withConclusions:Short term and local application of DHT at low doses in patients with micropenis could accelerate penile growth effectively without evident side effects; however, precautions still need be taken due to the paucity of long term study and the lack of ideal DHT dosage.

scholarly journals Short-term and long-term treatment with propafenone: determinants of arrhythmia suppression, persistence of efficacy, arrhythmogenesis, and side effects in patients with symptoms.

Heart ◽  
1992 ◽  
Vol 67 (6) ◽  
pp. 491-497 ◽  
Author(s):  
M Zehender ◽  
S Hohnloser ◽  
A Geibel ◽  
A Furtwangler ◽  
M Olschewski ◽  
...  
Keyword(s):  
Side Effects ◽  
Term Treatment ◽  
Short Term ◽  
Long Term Treatment

The Shift towards Smart, Green and Integrated Raw Materials Efficiency

2014 ◽  
Vol 718 ◽  
pp. 105-109
Author(s):  
Eva Oravcová ◽  
Miroslav Zelko
Keyword(s):  
Decision Support ◽  
Raw Materials ◽  
Decision Makers ◽  
Short Term ◽  
Supervision System ◽  
Requirements Development ◽  
And Control ◽  
Term Data

Comprehensive environmental observation, eco-innovation and smartization are essential to ensure the delivery of the long-term data and information required to address the shift towards smart, green and integrated raw materials efficiency. For this reason we need the mine-wide digitalization and informatization base model, an advanced mine-wide decision support system and a smart supervision system to supervise and control the production, back to predefined short-term production targets with most likelihood and optimal approaches. There are three main steps to be taken: analysis, evaluation and determination of the shift requirements, development of the models as well as modeling of the scenarios and connection to the smart platform for the support of the decision makers. The paper aims to consider what would be required for a raw materials area to operate as a modern smart technology-supported business. It attempts to provide a vision of some future smart architectures scenarios.

Treatment of Acute Mania

CNS Spectrums ◽  
2003 ◽  
Vol 8 (12) ◽  
pp. 917-928 ◽  
Author(s):  
Paul E. Holtzheimer ◽  
John F. Neumaier
Keyword(s):  
Clinical Practice ◽  
Side Effects ◽  
Drug Administration ◽  
Mood Stabilizers ◽  
Acute Mania ◽  
Treatment Resistant ◽  
Short Term ◽  
The Past ◽  
Term Tolerability

AbstractMood stabilizers have evolved considerably over the past decade. Lithium, divalproex, and olanzapine are currently Food and Drug Administration-approved for the treatment of acute mania. A number of new and traditional medications have also been tested and are commonly used in clinical practice. Several strategies for managing treatment-resistant mania have been suggested, but few have been rigorously tested. Emphases on rapid stabilization and fewer side effects have raised the bar for what is expected from mood stabilizers and the successful treatment of mania involves a delicate balance between swiftness, short-term tolerability, and long-term safety.

N-Acetylcysteine’s Attenuation of Fatigue After Repeated Bouts of Intermittent Exercise: Practical Implications for Tournament Situations

2011 ◽  
Vol 21 (6) ◽  
pp. 451-461 ◽  
Author(s):  
James N. Cobley ◽  
Chris McGlory ◽  
James P. Morton ◽  
Graeme L. Close
Keyword(s):  
Side Effects ◽  
Muscle Fatigue ◽  
Intermittent Exercise ◽  
Adaptive Responses ◽  
Short Term ◽  
Treatment Dose ◽  
Gastrointestinal Side Effects ◽  
Matched Design ◽  
Over Time

Production of reactive oxygen species (ROS) during muscle contractions is associated with muscle fatigue and damage in the short term and adaptive responses in the long term. When adaptation is inconsequential acute antioxidant supplementation may be able to attenuate muscle fatigue and damage to enhance performance. This study aimed to determine the effects of acute oral N-acetylcysteine (NAC) supplementation on Yo-Yo Intermittent Recovery Test Level 1 (YIRT-L1) performance after repeated bouts of damaging intermittent exercise. In a pair-matched design, 12 recreationally trained men engaged in 6 d of either NAC (n = 6) or placebo (n = 6) supplementation. After a treatment-loading day, participants completed 3 testing sessions, on alternating days, consisting of a preexercise isokinetic dynamometry (IKD) test, a damaging intermittent-exercise protocol, YIRT-L1, and a postexercise IKD test. Another IKD test was completed on the 2 intervening d. NAC treatment resulted in a significant preservation of YIRT-L1 performance (p ≤ .0005). IKD performance significantly deteriorated over time at all contraction speeds, and this deterioration was not influenced by treatment group. Plasma creatine kinase values increased significantly over time (p = .002) and were significantly greater in the NAC group than in the placebo group (p = .029). NAC induced mild gastrointestinal side effects. NAC supplementation may be a useful strategy to enhance performance during short-term competitive situations when adaption is inconsequential. Titration studies to elucidate a treatment dose that enhances performance without inducing side effects are now required.

scholarly journals AN UPDATE ON TOXICITY OF THERAPEUTIC RADIONUCLIDES

2021 ◽  
Vol 9 (4) ◽  
Author(s):  
Dilip Vallathol ◽  
Raghunadharao Digumarti
Keyword(s):  
Side Effects ◽  
Short Term ◽  
Targeted Radiotherapy ◽  
Myeloid Neoplasms ◽  
Strontium 90 ◽  
Gonadal Toxicity ◽  
Iodine 131 ◽  
The Many ◽  
Yttrium 90

Targeted radiotherapy is an evolving and promising modality of cancer treatment. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the possibility of assessing the uptake by the tumor prior to the therapy. A number of radionuclides, such as iodine-131 (131I), phosphorus-32 (32P), strontium-90 (90Sr), and yttrium-90 (90Y), have been used successfully for the treatment of many benign and malignant disorders. The toxicity to radionuclides has come into vogue with its increasing utilization for multiple indications. Short term hematological toxicities include cytopenias and long term hematological toxicities include myeloid neoplasms. Non hematological toxicities commonly include renal and hepatotoxicity and long term toxicities like gonadal toxicity. This review focuses on the toxicities which need to be monitored during use of therapeutic radionuclides.

scholarly journals The effects of phthalates on Nereis diversicolor

2016 ◽  
Author(s):  
Ashwaq Alnemari ◽  
Joerg Hardege
Keyword(s):  
Culture System ◽  
Phthalate Esters ◽  
Aquatic Organisms ◽  
Consumer Products ◽  
Short Term ◽  
Hediste Diversicolor ◽  
Materials Used ◽  
Dissolved Chemicals ◽  
The Impact

Animals are exposed, in the natural environment, to a range of human activity related dissolved chemicals that are potentially impacting on their fitness. The animals responses to such stress determines its fitness, physiology and in case of chemical signals also its behaviour. If physical or chemical changes in the ecosystem make the detection of such a chemical impossible, then it can be reasonably assumed that vital behaviours of the animal will be significantly altered. Plastics are lighter, more durable, stronger and cheaper than other materials used for the same purposes, making them most suitable for producing a very broad range of goods and products. However, these same properties also make them serious environmental hazards i.e. they are easily carried and dispersed by water over long distances, and stopped by barriers and settle in the form of sediments that can persist for centuries. Phthalate esters are widely used as additives to offer flexibility to polyvinyl chloride (PVC) resins (Graham, 1973). DEHP and DMP are the most frequently used plasticizer in PVC formulas in consumer products (Metcalf et al. 1973; Carnevali et al. 2010). In general phthalate esters harmful environmental and human health effects are well documented and a range of studies documented harmful effects on both land and aquatic organisms (Metcalf et al. 1973; Lithner, et al. 2009). Neanthes (Nereis, Hediste) diversicolor is a bio-indicator species to monitor levels of pollution in a particular environment i.e. to by quantify levels of contaminant presents in the worms. Measuring these in N. diversicolor makes it possible to estimate and monitor levels of contamination in marine environments. The worms are easy to keep in laboratory conditions and can be collected in large numbers in the field and used as model species since the 1950s (Scaps, 2002). The main aim of this study is to investigate and determine the fate of phthalates in a Nereis culture system and to assess the impact of phthalates upon fitness such as feeding behaviours. For this worms are exposed to different concentration of DEHP (0.05, 2, and 10 ug/mL) over short term (days) and long term (3 months / lifespan). The aim of short term of exposure was to determine the fate of phthalates in a Nereis culture system to examine if phthalate degradation takes place. GC-MS is used to measure the phthalates. Liquid: liquid extraction was used to extract phthalates from water and worm tissue whereas accelerated solvent extraction was used to extract phthalates from sediment. The aim of long term of exposure was to investigate and assess the impact of phthalates on animals’ functional traits (feeding response).

scholarly journals Central infusion of GLP-1, but not leptin, produces conditioned taste aversions in rats

1997 ◽  
Vol 272 (2) ◽  
pp. R726-R730 ◽  
Author(s):  
T. E. Thiele ◽  
G. Van Dijk ◽  
L. A. Campfield ◽  
F. J. Smith ◽  
P. Burn ◽  
...  
Keyword(s):  
Side Effects ◽  
Food Intake ◽  
Consummatory Behavior ◽  
Central Administration ◽  
Short Term ◽  
Nonspecific Effects ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Ob Protein

Leptin (ob protein) and glucagon-like peptide-1-(7-36) amide (GLP-1) are peptides recently proposed to be involved in the regulation of food intake. Although the ability of exogenous leptin and GLP-1 to modulate consummatory behavior is consistent with the suggestion that these peptides are endogenous regulatory agents, central administration of these peptides may have aversive side effects, which could explain the anorexia. In the present experiment, exposure to a saccharine taste was immediately followed by central administration of leptin or GLP-1 to determine if these drugs could produce a conditioned taste aversion (CTA) in rats. At doses equated for producing comparable reductions in short-term food intake, GLP-1, but not leptin, generated a robust CTA. Although leptin caused no aversion, this peptide was the only drug to cause relatively long-term reductions in food consumption (16 h) and body weight (24 h). Hence, the results indicate that central GLP-1 produces aversive side effects, and it is argued that these nonspecific effects may explain the anorectic actions of GLP-1.

Natural Jerusalem artichoke syrups with prebiotic properties

2021 ◽  
pp. 15-21
Author(s):  
Сергей Леонидович Филатов ◽  
Марина Сергеевна Михайличенко ◽  
Сергей Михайлович Петров ◽  
Надежда Михайловна Подгорнова
Keyword(s):  
Weight Control ◽  
Raw Materials ◽  
Jerusalem Artichoke ◽  
Comparative Characteristic ◽  
Plant Materials ◽  
Low Calorie ◽  
Plant Raw Materials ◽  
High Fructose ◽  
Materials Used ◽  
Low Glycemic Index

Выполнен обзор коммерчески доступных сиропов из различного натурального растительного сырья, используемых в качестве альтернативных сахару подслащивающих веществ пониженной калорийности, здорового углеводного профиля, с пребиотическими свойствами. Приведена общая характеристика и отражен химический состав растительного сырья (топинамбур, цикорий) и сиропов (из сорго, якона, агавы, кленовый, пальмовый, кукурузный), минеральные вещества (макро- и микроэлементы), витамины. Предложена и в производственных условиях апробирована современная инновационная мембранная технология получения фруктозно-глюкозного и фруктоолигосахаридного биосиропов из топинамбура, направленная на наиболее полное использование и сохранение природного состава клеточного сока растения. Фруктоолигосахариды топинамбура обладают пребиотическими свойствами, являются низкокалорийными подсластителями, создают чувство сытости, способствуют контролю массы тела, облегчают пищеварение, имеют низкий гликемический индекс и не вызывают кариес. Для апробации использования в пищевой промышленности приведена сравнительная характеристика сиропов из сахарной свеклы и топинамбура, которые получены на промышленном предприятии. Биосиропы с высоким содержанием фруктозы и олигофруктозный сироп изучены по углеводному составу и протестированы в приготовлении безалкогольных напитков. A review of commercially available syrups from a variety of natural plant materials used as alternatives to sugar, low-calorie sweeteners with a healthy carbohydrate profile and prebiotic properties is reviewed. The general characteristics and the chemical composition of plant raw materials (Jerusalem artichoke, chicory) and syrups (sorghum, yacon, maple, agave, palm, corn) are given: minerals (macro- and microelements), vitamins. A modern innovative membrane technology for producing fructose-glucose and fructo-oligosaccharide biosyrups from Jerusalem artichoke has been proposed and tested in production conditions, aimed at the most complete use and preservation of the natural composition of the plant cell juice. Jerusalem artichoke fructo-oligosaccharides have prebiotic properties, are low-calorie sweeteners, create a feeling of satiety, promote weight control, facilitate digestion, have a low glycemic index and do not cause tooth decay. For approbation of use in the food industry, a comparative characteristic of sugar beet and Jerusalem artichoke syrups, which are obtained at an industrial enterprise, is given. High fructose biosyrups and oligofructose syrup have been studied for their carbohydrate composition and tested in the preparation of soft drinks.

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