Linfoma di Burkitt in età pediatrica

2021 ◽  
Vol 24 (6) ◽  
pp. 175-184
Author(s):  
Fabio Timeus ◽  
Matilde Piglione ◽  
Franca Fagioli ◽  
Aldo Ravaglia
Keyword(s):  
Late Effects ◽  
Well Being ◽  
Developed Countries ◽  
Primary Care Doctor ◽  
High Dose ◽  
Childhood And Adolescence ◽  
Myc Oncogene ◽  
Alternating Chemotherapy ◽  
Short Courses ◽  
Chemotherapy Agents

Sporadic Burkitt lymphoma (BL) accounts for about 80% of non-Hodgkin lymphomas in childhood and adolescence, with an incidence of 3-5 cases per million in developed countries. The hallmark of LB is the deregulation of MYC oncogene, usually caused by the [t(8;14)(q24;q32)] translocation, involving the gene of immunoglobulin heavy chain. BL is a very aggressive neoplasm, with a doubling time of 12-24 hours and its diagnosis and therapy are a true haematologic emergency. Abdomen, head and neck are the most frequent sites of presentation and the involvement of ileo-caecal area can cause an intussusception as first manifestation of the disease. <br> BL and mature B-cell acute leukaemia (the leukaemic manifestation of BL) share the same therapeutic approach, intensive short courses with multiple alternating chemotherapy agents, the use of high dose-methotrexate and intrathecal CNS prophylaxis. The outcomes are satisfactory: in Italy during the period 1997-2014 the children with BL were treated according to the AIEOP LNH-97 protocol, achieving more than 90% of 5 year-survival. <br> In the last decades, the prognosis for children and adolescents with cancer has dramatically improved and the increasing number of long-term survivors has focused the attention of clinicians on the late effects of cancer and its therapy. A multidisciplinary follow up and a correct transition from the paediatrician to the primary care doctor plays a central role not only in the early detection and therapy of late effects of cancer but also in supporting the patient to realize their physical, mental and social well-being as much as possible.

Growth and Social Capital: Empirical Analysis of the Relationship

2019 ◽  
pp. 128-134
Author(s):  
Ksenia V. Bagmet
Keyword(s):  
Economic Growth ◽  
Social Capital ◽  
Economic Development ◽  
Social Development ◽  
Empirical Analysis ◽  
Panel Data Analysis ◽  
Well Being ◽  
Developed Countries ◽  
International Institute ◽  
Level Of Economic Development

The article provides an empirical test of the hypothesis of the influence of the level of economic development of the country on the level of development of its social capital based on panel data analysis. In this study, the Indices of Social Development elaborated by the International Institute of Social Studies under World Bank support are used as an indicators of social capital development as they best meet the requirements for complexity (include six integrated indicators of Civic Activism, Clubs and Associations, Intergroup Cohesion, Interpersonal Safety and Trust, Gender Equality, Inclusion of Minorities), comprehensiveness of measurement, sustainability. In order to provide an empirical analysis, we built a panel that includes data for 20 countries divided into four groups according to the level of economic development. The first G7 countries (France, Germany, Italy, United Kingdom); the second group is the economically developed countries, EU members and Turkey, the third group is the new EU member states (Estonia, Latvia, Lithuania, Romania); to the fourth group – post-Soviet republics (Armenia, Georgia, Russian Federation, Ukraine). The analysis shows that the parameters of economic development of countries cannot be completely excluded from the determinants of social capital. Indicators show that the slowdown in economic growth leads to greater cohesion among people in communities, social control over the efficiency of distribution and use of funds, and enforcement of property rights. The level of tolerance to racial diversity and the likelihood of negative externalities will depend on the change in the rate of economic growth. Also, increasing the well-being of people will have a positive impact on the level of citizens’ personal safety, reducing the level of crime, increasing trust. Key words: social capital, economic growth, determinant, indice of social development.

Foundations of International Aid

1960 ◽  
Vol 329 (1) ◽  
pp. 137-143
Author(s):  
Jane M. Hoey
Keyword(s):  
Well Being ◽  
International Aid ◽  
Developed Countries ◽  
The United States ◽  
Moral Foundations ◽  
Economic Progress ◽  
Political Independence ◽  
The Developed Countries ◽  
The Individual

The newly developing countries desire not only political independence but also economic progress for their people—a progress which they can see, and are now aware of, in the rest of the world. The role of the developed countries is to extend aid to the needy. Moral foundations underlie the donor's contributions, but they are more than that, they are the means for acquiring support for international aid in the donor's country. The United States must assume the leader ship among' the free nations in granting aid; she must accept this role because of her economic achievements and technologi cal advantages. Donators of such aid should take cognizance of the complementary character and interrelatedness of economic and social development. For economic development, however much it is sought, is not an end in itself, rather the aim is the well-being and happiness of the individual. Such a goal neces sitates economic aid accompanied by social aid. Social welfare can also be a vehicle to achieve peace, inasmuch as people-to- people relationships generate brotherly love—the only lasting foundation for peace.—Ed.

Quality of life in long-term childhood cancer survivors and the relation of late effects and subjective well-being

2004 ◽  
Vol 13 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Sigrid Pemberger ◽  
Reinhold Jagsch ◽  
Eva Frey ◽  
Rosemarie Felder-Puig ◽  
Helmut Gadner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Late Effects ◽  
Well Being ◽  
Childhood Cancer Survivors ◽  
Subjective Well Being

From Piggy Banks to Significant Others: Associations Between Financial Socialization and Romantic Relationship Flourishing in Emerging Adulthood

2021 ◽  
pp. 0192513X2110575
Author(s):  
Ashley B. LeBaron-Black ◽  
Matthew T. Saxey ◽  
Toby M. Driggs ◽  
Melissa A. Curran
Keyword(s):  
Emerging Adulthood ◽  
Emerging Adults ◽  
Financial Distress ◽  
Romantic Relationship ◽  
Well Being ◽  
Childhood And Adolescence ◽  
Financial Socialization ◽  
Financial Outcomes ◽  
Financial Behaviors ◽  
Relationship Outcomes

While a plethora of research has found that parent financial socialization during childhood and adolescence is linked with financial outcomes in emerging adulthood, recent literature suggests that financial socialization may also impact romantic relationship outcomes in emerging adulthood. Utilizing a sample of 1,950 U.S. emerging adults, we test whether retrospectively recalled parent financial socialization is associated with romantic relationship flourishing and whether this association is mediated by financial behaviors and financial distress. We found that financial socialization was positively associated with financial behaviors and relationship flourishing and was negatively associated with financial distress. Further, financial behaviors partially mediated the association between financial socialization and relationship flourishing, while financial distress did not mediate the association. Together with previous literature, these findings provide useful information for therapists and educators in their pursuit to promote robust parent financial socialization in childhood and adolescence and both financial and relational well-being in emerging adulthood.

Macroeconomic conditions are only an illusion, not the solution, to firm sustainability: unveiling the new dimension of stakeholder well-being

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Zahid Irshad Younas ◽  
Mahvesh Khan ◽  
Mamdouh Abdulaziz Saleh Al-Faryan
Keyword(s):  
Well Being ◽  
Developed Countries ◽  
Macroeconomic Performance ◽  
Content Type ◽  
Macroeconomic Conditions ◽  
Us Economy ◽  
The Us ◽  
The Usa ◽  
Negative Impacts ◽  
The One

Purpose The purpose of the study is to explore the misconception that in developed countries, macroeconomic performance lead to sustainable firms or improves stakeholder well-being. The results may be the opposite or even worse. Design/methodology/approach This study examined this misconception using balanced panel data from 1,122 firms from different sectors of the US economy and data on macroeconomic performance from the World Bank. Findings The results of the one-step generalised method of moments indicate that most macroeconomic performance indicators had significant and negative impacts on firm sustainability and stakeholder well-being. Practical implications From a societal perspective, the results illustrate that the fruits of macroeconomic performance of the US economy do not reach stakeholders through firms’ sustainability. Thus, linking the economy’s macroeconomic performance with firm sustainability is vital for sustainably uplifting society and for stakeholder well-being. Originality/value From a policy perspective, this study reveals that the greater focus on macroeconomic performance in the USA over the past decades has resulted in lower firm sustainability because of the malfunctioning of social, economic, environmental and governance factors. This has negatively influenced stakeholder well-being in the country.

World Society, World Polity, and the Carbon Intensity of Well-Being, 1990–2011

2017 ◽  
Vol 3 (4) ◽  
pp. 403-435 ◽  
Author(s):  
Jennifer E. Givens
Keyword(s):  
Well Being ◽  
Developed Countries ◽  
World Society ◽  
Carbon Intensity ◽  
Global Integration ◽  
World Polity ◽  
Production And Consumption ◽  
Modeling Techniques ◽  
Developed Nations

Research on the carbon intensity of well-being (CIWB), a measure representing a country's development in terms of both environmental and human well-being, often explores the role of economic development, while the effects of other aspects of global integration remain under-explored. I use macro-comparative sociological perspectives to investigate the extent to which theories of global integration help explain variation in countries’ CIWB over time. I evaluate propositions drawn from neoinstitutional world society and world polity theories using longitudinal modeling techniques to analyze data from 81 countries from 1990 to 2011. I also examine subsets of more and less developed countries and compare production- and consumption-based measures of CIWB. I find that world society/world polity integration is associated with a reduction in CIWB only in more developed nations, and only when using the production measure for CO2 emissions, highlighting the complexities of sustainable development in an unequal global system.

scholarly journals Wealth Inequality as a Predictor of Subjective Health, Happiness and Life Satisfaction among Nepalese Women

2018 ◽  
Vol 15 (12) ◽  
pp. 2836 ◽  
Author(s):  
Zhifei He ◽  
Zhaohui Cheng ◽  
Ghose Bishwajit ◽  
Dongsheng Zou
Keyword(s):  
Economic Status ◽  
Wealth Inequality ◽  
Well Being ◽  
Developed Countries ◽  
Subjective Health ◽  
Household Wealth ◽  
The Body ◽  
Status Report ◽  
Wealth Status ◽  
Cross Sectional

Socioeconomic status has shown to be associated with subjective health, well-being, satisfaction with overall life and estimation of happiness. The body of research concerning the question of whether higher economic status leads to better health and well-being are mostly from developed countries. The present study was therefore conducted among women in Nepal with an aim to investigate whether household wealth status is associated with satisfaction about (1) self-reported health, (2) happiness, and (3) life overall. Methods: Subjects were 5226 Nepalese women aged between 15 and 24 years. Cross-sectional data were extracted from round 5 of the Nepal Multiple Indicator Cluster Survey (NMICS), conducted in 2014, and analyzed using chi-square tests of association, bivariate and multivariable regression methods. Results: Wealth status was significantly associated with satisfaction about health, estimation of happiness and satisfaction. Compared with women in the poorest households, the odds of positive estimation about overall happiness were respectively 30% higher for poorer (p < 0.0001; 95% CI = 1.653–3.190), 80% higher for middle (p = 0.001; 95% CI = 1.294–2.522), 64% higher for richer (p = 0.006; 95% CI = 1.155–2.326), and 40% higher for richest households. The odds of reporting satisfaction about life were respectively 97% higher for poorer (p < 0.0001; 95% CI = 1.680–2.317), 41% higher for middle (p < 0.0001; 95% CI = 1.165–1.715), 62% higher for richer (p < 0.0001; 95% CI = 1.313–2.003), and 31% higher for richest households (p = 0.043; 95% CI = 1.008–1.700). Conclusion: Our results conclude that women in households with lower wealth status report poorer subjective health, quality of life and happiness. However, the findings need to be interpreted in light of the existing sociocultural conditions mediating the role of household wealth status on women’s lives.

scholarly journals Foreign Economic Development: The Need and How Well It Is Being Met

1970 ◽  
Vol 2 (1) ◽  
pp. 53-59
Author(s):  
Ralph K. Davidson
Keyword(s):  
Quality Of Life ◽  
Economic Development ◽  
Gross National Product ◽  
Well Being ◽  
Developed Countries ◽  
Land Area ◽  
The People ◽  
Per Capita ◽  
Ultimate Objective

Today, the need for economic development is self-evident to the millions of people in Asia, Africa and Latin America who suffer from malnutrition, are ill-housed, poorly educated, and either unemployed or grossly underemployed. The ultimate objective of economic development is to raise the standard of life – the quality of life - for the mass of the people, to widen their area of choice, to open up new opportunities for human well-being. The less developed countries have two-thirds of the 3.5 billion people but receive only 12.5 percent of the world's gross national product. Life appears to be an economic treadmill with the future blighted by an excessive rate of population growth for millions of people. India provides a good illustration of the problem. With an estimated population of 525 million at mid-1968, India had 15 percent of the world's population, 2.4 percent of the world's land area, hardly 2 percent of the world's income, and an annual per capita income level of around $75.

Mindfulness and yoga self-care workshop for Northern Ugandan teachers: A pilot study

2020 ◽  
Vol 41 (4) ◽  
pp. 351-367
Author(s):  
M. Kyle Matsuba ◽  
Lenny Williams
Keyword(s):  
School Psychologists ◽  
Low Income ◽  
Teacher Stress ◽  
Self Care ◽  
Well Being ◽  
Developed Countries ◽  
Wait List ◽  
Post Conflict ◽  
Sub Saharan ◽  
European Counterpart

Teacher stress is evident in many developed countries; however, teacher stress is also evident in many low-income sub-Saharan countries such as Uganda where teachers face additional challenges compared to their North American/European counterpart. The goal of this study was to pilot test a mindfulness and yoga self-care workshop designed for teachers working in post-conflict Northern Uganda to help them cope with stress. Twenty teachers participated in the workshop and were compared to a group of matched wait-list teachers on psychological well-being measures. Results show that self-care teachers showed greater reductions in levels of anger, fear, sadness and perceived hostility, and greater increases in levels of emotional support and friendship compared to wait-list teachers. Moreover, longitudinal exploratory data analyses suggest that many of these effects gradually emerge over the course of the three-month school term. These finds are discussed in the context of how school psychologists can help teachers in developing countries through from yoga-based, mindfulness-type programs, and the need for more scaled-up research.

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