scholarly journals Possible association of stroke with higher whole blood viscosity: study in a high altitude (Cusco 3399 masl)

2021 ◽  
Author(s):  
Charles Huamani Saldaña ◽  
Franklin Miranda- Solis ◽  
Víctor Oré Montalvo ◽  
William Bayona ◽  
Carlos Perez ◽  
...  
Keyword(s):  
High Altitude ◽  
Blood Viscosity ◽  
Direct Methods ◽  
Cross Sectional Study ◽  
Plasma Viscosity ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Viscosity Study ◽  
The Difference ◽  
The City

Background. Risk factors for stroke have been extensively studied, however, few studies have been carried out in high-altitude cities. Objectives. To evaluate the difference in blood viscosity, using direct methods, in stroke patients versus patients without stroke to discover any possible association. Design and setting. A cross-sectional study was carried out in the city of Cusco, Peru (3399 m.a.s.l). Methods: Participants included stroke patients with less than three days of illness and controls without stroke. Viscosity levels were measured in all patients using a cone-plate viscometer. Blood viscosity was evaluated at 10, 20, 30 and 40 revolutions per minute (RPM) because blood is considered a nonNewtonian fluid. Plasma viscosity was evaluated at 100RPM. All viscosity units are expressed as means standard deviations (SD) in centipoises (cP). Results: A total of 204 patients were included (61 cases/143 controls). The mean age was 67.5 (SD:15.9), and 88 (43%) were women. The means of blood viscosity for 10, 20, 30RPM in the stroke cases were 5.85cP (SD:1.21), 5.22cP (SD:1.09), and 4.91cP (SD:1.02), and 4.81cP (SD:1.02) respectively. For the controls were of 5.57cP (SD:1.19), 4.89cP (SD:4.85), 4.63cP (SD:0.97), 4.56cP (SD:0.95), respectively. All measured means were tested with significant differences (p <0.01). Plasma viscosities were 1.43cP (SD:0.17) for the stroke cases and 1.49cP (SD:0.23) for controls (p=0.05). Conclusions: This study found that blood viscosity is 0.3cP higher in stroke patients. This suggests that blood viscosity could play a role in the etiology. The results presented are preliminary and the study is still under development.

Blood Viscosity, Glycaemic Control and Retinopathy in Insulin-Dependent Diabetes

1982 ◽  
Vol 63 (2) ◽  
pp. 211-216 ◽  
Author(s):  
P. Y. W. Poon ◽  
T. L. Dornan ◽  
C. Orde-Peckar ◽  
R. Mullins ◽  
A. J. Bron ◽  
...  
Keyword(s):  
Cell Volume ◽  
Blood Viscosity ◽  
Packed Cell Volume ◽  
Cross Sectional Study ◽  
Plasma Viscosity ◽  
Glycosylated Haemoglobin ◽  
Trend Test ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Low Shear

1. In a cross-sectional study, 32 insulin-treated diabetic patients had elevated low shear (27·1 vs 22·1 mPa s, P < 0·05) and high shear blood viscosity (5·4 vs 5·0 mPa s, P < 0·05) when compared with 10 non-diabetic controls. After correction to 45% packed cell volume, the abnormality had a tendency to be greater in patients with proliferative (mean low shear viscosity, 30·8 mPa s) than background (29·2 mPa s) or nil/minimal retinopathy (27·6 mPa s, 0·05 < P < 0·07, permutational trend test). 2. The fibrinogen levels were higher in the diabetic group (P < 0·05) and correlated with the low shear blood viscosity (rs = 0·38, P < 0·05). 3. In a prospective study, 74 insulin-treated diabetic patients with background retinopathy were randomized into two groups. Thirty-six patients were on attempted improved therapy (A group); in these the mean glycosylated haemoglobin (Hb A1c) fell within 1 year (11·6 to 10·1%, P < 0·001). Both the corrected low shear blood and plasma viscosity fell similarly (P < 0·001). The fall was greater than in those patients who were kept on usual therapy (U group) and whose glycosylated haemoglobin did not change significantly (11·7 to 11·4%) over the year. 4. The effect of diabetes on blood viscosity may not be a direct pathological factor, as the same increased viscosity would be produced by a mean increase of 1·7% in packed cell volume, compared with a population range of 14% packed cell volume.

Blood viscosity responses to maximal exercise in endurance-trained and sedentary female subjects

1985 ◽  
Vol 59 (2) ◽  
pp. 348-353 ◽  
Author(s):  
D. G. Martin ◽  
E. W. Ferguson ◽  
S. Wigutoff ◽  
T. Gawne ◽  
E. B. Schoomaker
Keyword(s):  
Blood Viscosity ◽  
Whole Blood ◽  
Cross Sectional Study ◽  
Plasma Viscosity ◽  
Physical Conditioning ◽  
Plasma Protein Concentration ◽  
Cross Sectional ◽  
Whole Blood Viscosity ◽  
Protein Pool ◽  
Female Subjects

To assess whether the rheological properties of blood might be altered by exercise, we measured whole blood viscosity, plasma viscosity, and its components in healthy female subjects before, immediately after, and 1 h after maximal upright exercise using the Bruce graded exercise protocol. Forty-seven female subjects (15 sedentary, 14 who ran 5–15 miles/wk, and 18 who ran greater than 50 miles/wk), ages 18–43 yr, were evaluated. Whole blood viscosity, measured with a cone and plate viscometer, increased an average of 12.6% with exercise. The increase was greater than can be attributed to the observed 8.9% increase in hematocrit alone due to a coincident increase in plasma protein concentration. However, plasma viscosity did not rise to the degree expected, likely due to a disproportionate observed loss of fibrinogen from the protein pool. These changes were independent of conditioning level or aerobic capacity. In this cross-sectional study, there appears to be no adaptive adjustment in females to physical conditioning that results in changes in blood viscosity.

scholarly journals Correlation between Acute Stroke and Concentration of Creatine Kinase Myocardial Band, Troponin T, Hemoglobin, and Electroyltes

2018 ◽  
Vol 14 (1) ◽  
pp. 71-80
Author(s):  
Destika Fahrina ◽  
Puji Pinta Sinurat ◽  
Aldy Sjarifuddin Rambe
Keyword(s):  
Creatine Kinase ◽  
Acute Stroke ◽  
Troponin T ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional ◽  
The Difference ◽  
Mean Concentration

Currently, there were only a few studies regarding the correlation between concentration of creatine kinase-myocardial band (CKMB), troponin T, hemoglobin, and electrolytes and acute stroke. This study aimed to understand the difference of mean concentration of CKMB, troponin T, hemoglobin, and electrolytes and their relationship with acute stroke. This was a cross sectional study using samples of 30 subjects who were selected with consecutive non random sampling. The subjects were acquired from acute stroke patients who were proven clinically and using computed tomography (CT) scan at Haji Adam Malik General Hospital. Demographic data were analyzed using descriptive statistic. The result showed that there were no difference in demographical characteristics between the subjects. In conclusion, there were no differences in mean of CKMB, troponin T, hemoglobin, and electrolytes in acute stroke. No correlation was found between acute stroke and concentration of CKMB, troponin T, hemoglobin, and electrolytes.

scholarly journals Zinc Serum Level Can Be a Risk Factor In Babol Stroke Patients?

2017 ◽  
pp. 10 ◽  
Author(s):  
Alijan AhmadiAhangar ◽  
Payam Saadat ◽  
Fatemeh Arab ◽  
Alireza Firozejahi ◽  
Mohamad Ali Biani ◽  
...  
Keyword(s):  
Risk Factor ◽  
Serum Level ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Stroke Patients ◽  
Cross Sectional ◽  
The Difference ◽  
And Control

Background and Purpose: Stroke is the second leading cause of death worldwide. The role of zinc as a contributing factor in the pathogenesis of stroke was considered.Results: This cross-sectional study on 100 stroke patients in Ayatollah Rouhani Hospital and 100 control group from cohort master plan "Ageing and health projects Amirkola was conducted. Zinc levels Serum simultaneously with other blood tests in the early hours of hospitalization. Zinc serum level was defined 70 to 120 micrograms per deciliter.Findings: The difference in mean of zinc level in patients and control group was not significant (102.6±47.7 in control group vs 100.9±35.8 in patient, p=0.7). Difference in zinc Serum level had statically significant with IHD (under70 0 cases (0), 70 to120 8 cases (24), 120 and upper24 cases (75), p=0.003) and with type of stroke (under70 (3(3.3) hemorrhagic vs 0(0) ischemic), 70 to 120(19(21) vs6 (60)), 120 and upper68 (75.6) vs4 (40), p=0.025) and also with patient and control group (under70 (3(3) in patient's vs 20(20) control group), 70 to 120(25(25) vs54 (54)), 120 and upper72 (72) vs26 (26), p<0001). In patients group 72(73.5) of cases had zinc serum level above 120. HLP difference was significant in patient and control group (50(50) in control group vs 35(35) in patients, p=0.04). Regression logistic show that IHD (p<0001, OR=30, CI=6-152), HLP (p<0001, OR=4, CI=9.09-1.85), zinc serum level (p<0001, OR=15.5, CI=4-59.8) had significant role.Conclusions: Zinc serum levels, Ischemic Heart Disease, Hyperlipidemia were most risk factor that play role in Babol stroke patients.

scholarly journals Blood Pressure in Inhabitants of High Altitude of Western Nepal

2012 ◽  
Vol 52 (188) ◽  
Author(s):  
S Shrestha ◽  
A Shrestha ◽  
S Shrestha ◽  
D Bhattarai
Keyword(s):  
Blood Pressure ◽  
High Altitude ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Blood Pressures ◽  
Study Population ◽  
Low Altitude ◽  
The Difference ◽  
The Given ◽  
Permanent Residents

Introduction: Studies conducted amongst the inhabitants of high altitude suggested that systolic and diastolic blood pressures are lower in the high than in low altitude population. So a study was designed to look at the blood pressure values among permanent residents of high altitudes of rural Western Nepal. Methods: This is a descriptive cross sectional study conducted at two different altitudes (2670 and 2950 meters) of Humla District, Nepal, looking at the blood pressure values among the permanent inhabitants at these altitudes.  Results: Total number of 137 subjects with 73 (53.3%) from 2950 meters and 64 (46.7%) from 2670 meters altitude were enrolled. Mean age of the study population was 35.29 years. Male were 57 (41.6%) and female 80 (58.4%). The difference in systolic blood pressures (118.59 and 114.66 mmHg, P=0.01) and mean arterial pressures (92.0 and 89.5 mmHg, P=0.02) at the altitudes of 2670 and 2950 meters were statistically significant whereas the difference in diastolic BP at these altitudes were not statistically significant. There was no significant correlation of BMI with blood pressure values and no difference was noted in the blood pressure values among the two different ethnic groups at the given altitudes.  Conclusions: Lower rate of hypertension was observed among the inhabitants of high altitude of rural western Nepal. Blood pressure was found to decreases with increase in altitude among permanent inhabitants of high altitude.  Keywords: altitude; blood pressure; high altitude inhabitants; hypertension; physiological change.  

scholarly journals Exploration of the Relationships between Hazard Perception and Eye Movement for Young Drivers

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Jingshuai Yang ◽  
Chengxin Liu ◽  
Pengzi Chu ◽  
Xinqi Wen ◽  
Yangyang Zhang
Keyword(s):  
Eye Movement ◽  
Cross Sectional Study ◽  
Hazard Identification ◽  
Cross Sectional ◽  
Hazard Perception ◽  
Identification Time ◽  
Young Drivers ◽  
Complex Scenes ◽  
The Difference ◽  
The City

Aiming at young drivers’ hazard perception (HP) and eye movement, a cross-sectional study was conducted in the city of Xi’an, China. 46 participants were recruited, and 35 traffic scenes were used to test drivers’ hazard perception and eye movement. The difference analysis and correlation analysis were carried out for the acquired data. The results suggest that some indices of hazard perception and eye movement are significantly correlated. A higher saccade speed is in the direction of higher hazardous scenes. Higher complex scenes result in smaller saccade angle. The number of hazards unidentified is negatively influenced by complexity degree and hazardous degree of traffic scenes, and similar associations are found between hazard identification time, complexity degree, and hazardous degree. The hazard identification time and the number of hazards slowly identified are positively affected by the number of fixations and the number of saccades. Meanwhile, differences in the hazardous degree evaluation, hazard identification time, number of hazards unidentified, number of fixations, and number of saccades are found in different types of traffic scenes. The results help us to improve the design of road and vehicle devices, as well as the assessment and enhancement of young drivers’ hazard perception skills.

scholarly journals GAMBARAN GANGGUAN KADAR NATRIUM SERUM PADA PASIEN STROKE DI RSUP PROF. DR. R.D. KANDOU MANADO

2013 ◽  
Vol 5 (2) ◽  
Author(s):  
Mieke A. H. N. Kembuan
Keyword(s):  
Acute Stroke ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Negative Influence ◽  
Inclusion Criteria ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Chronic Disability ◽  
The Mean ◽  
The Difference

Abstract: World-wide, stroke is a main public health problem. It is one of the leading causes of chronic disability and death. Both hyponatremia and hypernatremia have a negative influence on the outcome of strokes. Hyponatremia is associated with increased mortality and complication rate, meanwhile hypernatremia is often found in the treatment of cerebral oedema in strokes. There are scarce data about natrium level disorders in acute strokes, especially from developing countries. This study aimed to describe the incidence of natrium disorders among acute stroke patients, and the difference of means of natrium based on the severity of the stroke and on GCS at admission. This was a hospital-based cross-sectional study. Samples consisted of 82 patients that met the inclusion criteria. The data of natrium levels were obtained from the hospital medical records. The results showed that the incidence of natrium disorders among acute stroke victims was 30%. The mean natrium level was 138.01 Meq/L (95% CI, 135.83-140.20). The incidence of hyponatremia was 28% while hypernatremia was 2%. There was no difference of mean-natrium-levels based on the severity of strokes (P > 0.05) and of GCS (P > 0.05). Conclusion: The incidence of natrium disorders among acute stroke patients was high but there was no difference between mean natrium levels based on the severity of strokes and of GCS. Keywords: natrium, natrium level disorders, acute stroke.     Abstrak: Stroke termasuk dalam masalah kesehatan utama di masyarakat dan merupakan penyebab utama kecacatan kronik dengan angka mortalitas tertinggi ke-2 di seluruh dunia. Baik hiponatremia maupun hipernatremia memberikan pengaruh negatif terhadap keluaran stroke. Hiponatremia meningkatkan angka kematian dan komplikasi, sedangkan hipernatremia sering terdeteksi bersamaan dengan penanganan edema serebral pada stroke. Data mengenai insidens gangguan kadar natrium pada stroke akut masih sangat kurang, terutama dari negara-negara berkembang. Penelitian ini bertujuan untuk mendapatkan insidens gangguan kadar natrium pada pasien stroke akut dan deskripsi perbedaan rerata kadar natrium pada berbagai derajat defisit neurologi dan GCS saat masuk rumah sakit. Penelitian ini bersifat potong lintang berbasis rumah sakit dengan jumlah sampel sebanyak 82 dan kriteri inklusi tertentu. Hasil penelitian memperlihatkan angka insidens gangguan kadar natrium pada stroke akut sebesar 30%. Rerata kadar natrium 138.01 Meq/L (95% CI, 135,83-140,20). Hiponatremia didapatkan pada 28% kasus sedangkan hipernatremia pada 2% kasus stroke akut. Tidak terdapat perbedaan bermakna antara rerata kadar natrium berdasarkan beratnya stroke dan GCS (P > 0,05). Simpulan: Insidens gangguan kadar natrium pada stroke akut tinggi. Tidak terdapat perbedaan bermakna antara rerata kadar natrium berdasarkan beratnya stroke dan GCS. Kata kunci: natrium, gangguan kadar natrium, stroke akut.

Perceived social support and burden of care of male and female caregivers of patient with schizophrenia

2017 ◽  
Vol 8 (1) ◽  
pp. 10
Author(s):  
Narendra Kumar Singh ◽  
Nishant Goyal
Keyword(s):  
Social Support ◽  
Perceived Social Support ◽  
Family Members ◽  
Well Being ◽  
Cross Sectional Study ◽  
Burden Of Care ◽  
Cross Sectional ◽  
Male And Female ◽  
The Social ◽  
The Difference

Background: Schizophrenia is associated with a high familial, social and economic burden. Schizophrenia is also associated with a high level of disability which may create impediments on the social and economic areas of the patients as well as on their respective family networks. Families with schizophrenia may encounter problems such as impairment of health and well being of other family members, restriction of social activities of the family members and shrinking of support from the social network. Aims: The present study examined the difference in perceived social support and burden of care between the male and female caregivers of patients with schizophrenia. Methods: This was a cross-sectional study examining the difference in perceived social support and burden of care between the male and female caregivers of patients with schizophrenia. The sample consisted of 60 (30 male and 30 female) caregivers of the patients with the diagnosis of schizophrenia as per ICD-10-DCR. Results and Conclusion: This study revealed that male caregivers perceived more social support and less burden of care as compared to female caregivers. Key words: Gender, social support, burden

Hepatitis A Seroprevalence Among Patients with Chronic Hepatitis B Infection: A Cross-Sectional Study in Iran During 2016-2017

2020 ◽  
Vol 20 (5) ◽  
pp. 748-751
Author(s):  
Seyed Ali Dehghan Manshadi ◽  
Neda Alijani ◽  
Mohammadreza Salehi ◽  
Omid Dadras ◽  
SeyedAhmad SeyedAlinaghi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatitis A ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Reasonable Approach ◽  
The Difference ◽  
Prevention Method

Introduction: The aim of this study was to determine the prevalence of exposure to hepatitis A by means of serologic markers in chronic hepatitis B patients, with the secondary aim of finding the best prevention method for hepatitis A infection in susceptible groups of our setting. Methods: During the period between 2016 and 2017, we recruited 403 hepatitis B patients aged more than 14 years and regularly attending the infectious diseases clinic at a referral university hospital, Tehran, Iran. A blood sample was collected from all the patients and tested for hepatitis A IgG. The data was analyzed by SPSS v.19. Results: Although none of the patients had previously received hepatitis A vaccine, the results for serologic level of hepatitis A IgG, demonstrated positive results in 379 (94%) cases. The mean age of patients with negative and positive IgG was 29.17 and 42.46 years, respectively; the difference was statistically significant (P≤0.001). The majority of seronegative patients were young adults aged < 25 years and 25 to 35 years (P <0.001). Conclusion: Seroprevalence of hepatitis A in chronic HBV patients in Iran is high. As HBV infected patients younger than 35 years could be seronagative for HAV infection, evaluation of these patients for HAV infection and vaccination of seronegative patients would be a reasonable approach.

Quality of life in Hungarian polio survivors

2021 ◽  
Author(s):  
Erika Viktória Miszory ◽  
Melinda Járomi ◽  
Annamária Pakai
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Sample Selection ◽  
Cross Sectional Study ◽  
Two Dimensions ◽  
Cross Sectional ◽  
Emotional Role ◽  
The Difference ◽  
Polio Survivors

Abstract Aim The number of Hungarian polio patients can be estimated at approximately 3000. Polio infection is currently affecting people 56–65 years of age. The aim of the study was to reveal the quality of life of patients living with polio virus in Hungary. Subject and methods The quantitative cross-sectional study was conducted in January–April 2017 among polyomyelitis patients living in Hungary. In the non-random, targeted, expert sample selection, the target group was composed of patients infected with poliovirus (N = 268). We have excluded those who refused to sign the consent statement. Our data collection method was an SF-36 questionnaire. Using the IBM SPSS Statistics Version 22 program, descriptive and mathematical statistics (χ2-test) were calculated (p < 0.05). Results The mean age of the members of the examined population is 63.5 years; 68.1% were women and 31.90% were men. The majority of the respondents were infected by the polyovirus in 1956 (11.9%), 1957 (24.3%), and 1959 (19.5%). Polio patients, with the exception of two dimensions (mental health, social operation), on the scale of 100 do not reach the “average” quality of life (physical functioning 23 points, functional role 36 points, emotional role 47 points, body pain 48 points, general health 42 points, vitality 50 points, health change 31 points). Conclusion The quality of life of polio patients is far below the dimensions of physical function, while the difference in mental health compared to healthy people is minimal. It would be important to educate health professionals about the existing disease, to develop an effective rehabilitation method.

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